1.Reconstruction of traumatic deficiency of forearm bone: report of Two Cases
Jung Man KIM ; Myung Sang MOON ; Han Joo KIM
The Journal of the Korean Orthopaedic Association 1980;15(2):346-349
Two cases of acquired absence of forearm bone secondary to compound comminuted fractures were treated by reconstructive surgery, which consist of surgical construction of one-bone forearm. The results of treatment were referred and the review of the literature was done concerning about surgical reconstruction of one-bone forearm.
Forearm
;
Fractures, Comminuted
2.Monoclonal antibody production and characterization for the measurement of plasma high density lipoprotein.
Journal of Korean Medical Science 1996;11(5):390-396
We prepared two monoclonal antibodies-A-I30 and A-I4 to HDL apo A-I-with the ultimate goals of expressing and overproducing the valuable immunodiagnostic single chain Fv by phage display libraries in E, coli. Monoclonal antibodies were produced by immunizing mice with apolipoprotein A-I, and purified from ascitic fluid by affinity chromatography on a Protein A Sepharose CL-4B column. The specificity of A-I30 and A-I4 was confirmed by ELISA and Western blotting. The dissociation constants(Kd) of antigen-antibody complex obtained by enzyme linked immunosorbent assay(ELISA) method were 2.25 x 10(-8) M for A-I30 and 2.15 x 10(-8) M for A-I4. The experimental values of Kd are shown to be close to those obtained by immunoprecipitation of the radiolabeled antigen. From the above results, it was shown that A-I30 and A-I4 could be provided as excellent reagents for the determination of plasma HDL concentrations in clinical specimens using ELISA.
Animal
;
Antibodies, Monoclonal/*immunology/isolation & purification
;
Antibody Affinity
;
Apolipoprotein A-I/*immunology
;
Blotting, Western
;
Hybridomas
;
Lipoproteins, HDL/immunology
;
Mice
;
Mice, Inbred BALB C
;
Tumor Cells, Cultured
3.The Internationalization of the Korean Radiological Society.
Young Goo KIM ; Kun Sang KIM ; Byung Ihn CHOI ; Man Chung HAN ; Seung Hyup KIM
Journal of the Korean Radiological Society 1995;33(3):333-337
Toward the beginning of the twenty-first century, the world experiences the dramatic changes in politics, economics and culture, and it is evident that the Korean medical field will not be able to survive provided it doesn't prepare ourselves to adapt to those changes. The Korean Medical Society held a forum for the active operation of the medical society, inviting several leading affiliated societies, to meet the needs of the times. This review describes the summary of the presentation that the authors made on behalf of the Korean Radiological Society in the forum, including the organization, current status of academic activity, current status of international communication, and problems encountered in the internationalization of the Korean Radiological Society.
Politics
;
Societies, Medical
4.Bronchiectasis: HRCT vs bronchography.
Sang Hoon CHA ; Jung Gi IM ; Yang Min KIM ; Man Chung HAN ; Young Soo SHIM
Journal of the Korean Radiological Society 1991;27(5):632-636
No abstract available.
Bronchiectasis*
;
Bronchography*
5.A Case of 9p-Syndrome due to a Balanced Maternal Translocation t(9;16) (p22;p13.2).
Kyeong Hee KIM ; Sang Dong SIN ; Jin Yeong HAN ; Jung Man KIM ; Lisa G SHAFFER
Korean Journal of Clinical Pathology 1997;17(4):676-680
The deletion 9p syndrome is a well characterized syndrome with about one hundred cases having been reported. Most patients have dysmorphic facial features, cardiac anomalies, and mental retardation. We report on a female infant with micrognathia, corneal opacity, cleft palace, cardiac anomaly, left polycystic kidney, and deletion 9p. Chromosome analysis and fluorescence in situ hybridization (FISH) showed her to have a derived chromosome 9 inherited from a maternal t(9;16) (p22;p13.2) by adjacent I segregation There are few reports of this particular chromosome rearrangement. We review deletion Sp syndrome.
Chromosomes, Human, Pair 9
;
Corneal Opacity
;
Female
;
Fluorescence
;
Humans
;
In Situ Hybridization
;
Infant
;
Intellectual Disability
;
Polycystic Kidney Diseases
6.The high resolution CT findings of sella in Korean hemorrhagic fever
Kee Hyun CHANG ; Man Chung HAN ; Suhng Gwon KIM ; Jung Sang LEE
Journal of the Korean Radiological Society 1984;20(3):424-429
It has been reported in autopsy that most of the patients with Korean hemorrhagic fever had necrotic areas inthe anterior lobe of the pituitary gland. The high resolution CT of sella was performed to demonstrate thepossible pituitary necrosis in consecutive 13 patients with Korean hemorrhagic fever. Only 3 patients demonstrate normal sellar findings. Ten (77%) out of 13 cases reveal abnormal findings; 2 patients show typical empty sellar and the rest (8 patients) reveal localized low denstiy area in the anterior portion of the sella turcica, which may be from partial empty sella, pituitary infarction or other unknown pathology. The low denisties within the sella will be discussed.
Autopsy
;
Hemorrhagic Fever with Renal Syndrome
;
Humans
;
Infarction
;
Necrosis
;
Pathology
;
Pituitary Gland
;
Sella Turcica
7.A study on the radiation effect on microvasculature of N-methyl-N-Nitrosourea-induced mammary carcinoma in rats
Sang Hoon BAE ; Kyoung Hwan KOH ; Chung Kie IM ; Sung Hwan HA ; Man Chung HAN
Journal of the Korean Radiological Society 1985;21(3):357-367
Mammary carcinoma was induced in rats by itravenous injection of N-methy-N-Nitrosourea. Microangiography was perfromed to evaluate the microvascular alterations in mammary carcinoma after irradiation. The tumors were givena single dose of 1.400 rads using Co-60 telethrapy unit with field size of 4 x 4 cm at 40 cm SSD. The dose ratewas 147.5 rads per minute. Microangiography was performed prior to irradiation and at one, two, and four weeksfollowing irradiation. The results are as follows: 1. Before irradiation, mammary carcinoma in rats tended to formlobules and the basic vasculature consisted of peripheral vascular pattern with central penetrating vessels. Theperipheral vascular pattern was always richer than that of the center. Irregular and tortuous vessles stretchedfrom the periphery into the center of lobule. 2. One week following irradiation, an increase in the number ofsmaller, tortuous vessels and decreased intervasular distance were obseved in the central portion of each lobule.This finding seems to be due to an improved filling of some previously existing but unfilled vessels. This maylead to improved metabolic changes and reoxygenation. 3. Later's changes of microvasculature after irradiation aretortuosity, irregularity, narrowing, abrupt tapering, fragmentation, and extravasation. These findings progressedafter a lapse of time. 4. The results can be considered as the microangiographic demonstration of the fact that reoxygenation after irradiation is mainly due to dilatation of the collapsed tumor vessels.
Animals
;
Dilatation
;
Microvessels
;
Radiation Effects
;
Rats
;
Silver Sulfadiazine
8.The Surgical Management of the Brachial Pleuxs Injuries
Sang Soo KIM ; Hyung Soon KIM ; Sung Man ROWE ; Ki Soo HAN
The Journal of the Korean Orthopaedic Association 1984;19(5):811-818
Microsurgery offers a more effective approach to the brachial plexus lesions than any treatments previously available. The authors have performed operation to the injured plexus by microsurgical techniques since 1980. We selected 15 patients whom we could follow more than one year and had results as follow. 1. The causes of injuries were traffic accident(7 cases), gun-shot injury(4 cases), stab wound(3cases), and belt injury (1 case). 2. Two patients had preganglionic lesion and 13 patients had postganglionic lesions, among which seven cases were supraclavicular and six cases were infraclavicular. Most frequently injured site was in upper two roots and upper trunk (7 cases). 3. All of them were treated by surgical intervention, 12 cases by interfascicular nerve graft using autogenous sural nerve, one case by intercostal neurotization, one case by neurolysis, and one case by exploration only. 4. Elbow flexor and deltoideus were involved easily by injury than other muscles, but they had best prognosis to the microsurgical treatment. 5. The recovery of wrist and finger function was poor but they were frequently preserved from injury.
Brachial Plexus
;
Elbow
;
Fingers
;
Humans
;
Microsurgery
;
Muscles
;
Nerve Transfer
;
Prognosis
;
Sural Nerve
;
Transplants
;
Wrist
9.An experimental study on radionuclide imaging of bowel infarction using (99m)Tc-pyrophosphate
Sang Hoon BAE ; Man Chung HAN ; Bo Yeon CHO ; Chang Soon KOH
Journal of the Korean Radiological Society 1981;17(1):149-156
99m Tc-pyrophosphate was investigated for use as an indicator of intestinal infarction in intussusceptedbowel. Irreducible intussusceptions were created in 18 rabbits by surgery. 99mTc-pyrophosphate was then injectedintravenously 6-12, 18, 24 and 30-40 hours later for external scanning. In 15 of the rabbits, infaractiondeveloped with intussusception, and 13 of them demonstrated increased uptake of 99m Tc-pyrophosphate on externalinvivo scintiscans. The remained 2 of them showed no evidence of increased uptake. So false negative cases were2(sensitivity 86.7%). The 3 rabbits without infarction showed no increased uptake of radionuclide. Specimenscanning confirmed increased uptake of radionuclide in the infarcted segments. These observations suggest that 99mTc-pyrophosphate is a reliable indicator of the intestinal infarction that sometimes occures with intestinal intussusception.
Infarction
;
Intussusception
;
Rabbits
;
Radionuclide Imaging
;
Technetium Tc 99m Pyrophosphate
10.Radiological evaluation of tricuspid atresia: an analysis of cineangiography in 11 cases
Hong Sik BYUNG ; Seung Ro LEE ; Sang Hook BAE ; Jae Hyung PARK ; Man Chung HAN
Journal of the Korean Radiological Society 1982;18(1):89-94
Total 11 cases of tricuspid atresia were diagnosed radiographically at Seoul National University Hospital in recent two years since 1979. Some characteristic radiological findings were analyzed in chest P-A view and cineangiographies of right atrium and left ventricle. The results are as follows; 1. Among the 11 cases, 4 cases were male and 7 cases were female. Age distribution was from 2 months to 19 years and mean age was 3 1/2 years. 2. Anatomaic types of those cases according to Keith's classification were as follows; type Ia in 2 cases, type Ib in7 cases, type Ic 1 case and type IIb in 1 case. 3. The cineangiographic features of tricuspid atresia are sequential filling of contrast media in the order of right atrium, left atrium, and left ventricle, and triangular filling defect at the base of the heart in all cases, and right atrial dimple in two cases. 4. It is essential for the diagnosis of tricuspid atresia to undertake cineangiographies of right atrium and left ventricle, and the interrelationship of great arteries.
Age Distribution
;
Arteries
;
Cineangiography
;
Classification
;
Contrast Media
;
Diagnosis
;
Female
;
Heart
;
Heart Atria
;
Heart Ventricles
;
Humans
;
Male
;
Seoul
;
Thorax
;
Tricuspid Atresia