1.Clinical study of arthrography in recent injuries of the lateral ligaments of the ankle.
Kwang Jin RHEE ; Sang Seug LIM ; Cyu Jong CHOI
The Journal of the Korean Orthopaedic Association 1992;27(7):1714-1723
No abstract available.
Ankle*
;
Arthrography*
;
Collateral Ligaments*
2.The Methods of Treatment in Estabilished Non-union of Femur Shaft
Bong Yeol LIM ; Sang Yo HAN ; Young An CHOI
The Journal of the Korean Orthopaedic Association 1982;17(2):366-375
The incidence of non-union in the shaft of femur is increasing gradually in spite of considerably improved methods of femoral fracture care. It is necessary that orthopaedic surgeon must draw attention to improve the method of treatment and to prevent the occurance of non-union. This paper presents the follow-up result of 27 cases among 30 established femoral shaft non-union cases, that were treated at the orthopaedic dept. of the National Medical Center from March 1971 to March 1980 by various methods. The study of this series shows the following. l. Amount 27 cases, male was predominant (82%), peak age group was 3rd & 4th decades (52%). 2. The causes of injury were auto-accident (56%), falling down accident (22%), direct blow (11%) & slipping down accident (11%). 3. The most common location was around the mid-shaft of femur (44.4%). 4. The probable causes of non-union were loosening of the implants & metal failure due to improper internal fixation (10 cases), incomplete reduction (7 cases), infection (5 cases) & inadenaute external immobilization (5 cases). 5. Excellent results were obtained by combined method of compression plate, screws & intramedullary nailing with additional autogenous bone graft.
Accidental Falls
;
Femoral Fractures
;
Femur
;
Follow-Up Studies
;
Fracture Fixation, Intramedullary
;
Humans
;
Immobilization
;
Incidence
;
Male
;
Methods
;
Transplants
3.A Case of Typhoid Fever Complicated with Empyema of Gall Bladder.
Sang Ho CHOI ; Jae You CHOI ; Byung Hak LIM ; Im Ju KANG ; Sang Hyup KIM
Journal of the Korean Pediatric Society 1988;31(3):386-390
No abstract available.
Empyema*
;
Typhoid Fever*
;
Urinary Bladder*
4.The Response of diabetic Rabbit Femoral Artey on the Electrical Stimulation and vasodilators.
Jin Soo LIM ; Youn Suk CHOI ; Sang Hun CHUNG ; Sok I YI ; Ho KWON ; Poong LIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(6):1125-1130
This experiment was aimed to investigate the contractile responses of the fermoral artery to the electrical stimulation and the inhibitory effects of verapamil and papaverine on the electrical stimulation of the fermoral artery in the control (n=46) and the diabetic rabbits(n=40). Diabetic rabbits were made by and administration of alloxan (100 mg/kg) intravenously and sacrified 8 weeks later. Femoral arterial rings 3 mm in length were taken and mounted on the force-displacement transducer for the measurements of isometric tension. All experiments were done in the aerated (95% O2 with 5% CO2)biological chamber filled with Kreb's solution and the initial tension of 1.5g was applied to the rings. After 1 hour of equilibrium of the rings, the contractile responses of the electrical stimulation on the femoral arterial rings were taken without vasoactive drugs and then, under verapamil and papaverine solution. And we compared the morphologic findings of the vessels in the two groups in relation to the functional changes by transmission electron miroscopy. The results are as follows: 1. The contractile responses in the presence of verapamil or papaverine solutions to the electrical stimulation were lowed significantly in the fermoral arterial rings of the diabetic rabbits compared with that of the control rabbits (verapamil; 10M~10M: p<0.01, papaverine; 10M & 10M: p<0.01). 2. Transmission electron microphotographs showed many morphological differences of the femoral arteries between the control and the diabetic rabbits. These were irregularities of the internal elastic lamina and the hypertrophy of the cytoplasms of the smooth muscle cells. And also, there were many vacuoles in the cytoplasm of the endothelial cells, lateral to the internal elastic laminaes, and between the smooth muscle cells in the diabetic rabbit femoral artery. By this study, we found that the contractile responses of the femoral arterial rings to the electrical stimulation were decreased in the diabetic rabbits, and the vasodiatory effects of verapamil and papaverine on the electrically stimulated femoral arterial rings were also lowered in the diabetic rabbits compared with the control rabbits. These changes of the vasular responses of the diabetic vessel may be associated with morphological changes manifested by transmission electron microscopy or any other functional derangement of the vessels.
Alloxan
;
Arteries
;
Cytoplasm
;
Electric Stimulation*
;
Endothelial Cells
;
Femoral Artery
;
Hypertrophy
;
Microscopy, Electron, Transmission
;
Myocytes, Smooth Muscle
;
Papaverine
;
Rabbits
;
Transducers
;
Vacuoles
;
Vasodilator Agents*
;
Verapamil
5.Comparison of Direct-labeling Method of Antibody with 99mTc and 188Re.
Chang Woon CHOI ; Sang Moo LIM ; Kwang Sun WOO ; Wee Sup CHUNG ; Tae Hyun CHOI ; Soo Jeong LIM
Korean Journal of Nuclear Medicine 1999;33(1):84-93
PURPOSE: We investigated the direct labeling method of antibody with 99mTc and 188Re and examined the stability and function of these labeled compounds in in vitro and in vivo. MATERIALS AND METHODS: Disulfide bond of nonspecific human IgG was reduced to -SH group by 2-mercaptoethanol. Stannous ion was used to reduce 99mTc and 188Re. The stability of 99mTc-IgG and 188Re-IgG was estimated upto 24 hrs. Biodistribution was evaluated in abscess bearing rats at 4 and 24 hr post-injection of 99mTc or 188Re labeled IgG. RESULTS: The number of -SH group per reduced IgG molecule was 2.34. The labeling yield of 99mTc-IgG and 188Re-IgG were 90% and 95%, respectively. The stability of 99mTc-IgG at 1, 4, 6 and 24 hr was 91%, 83%, 78%, 7% and that of 188Re-IgG, high uptake was found on kidney, blood, stomach and abscess (9.42+/-0.68, 1.43+/-0.24, 0.86+/-0.18, 0.72+/-0.10 %ID/g, respectively). The uptakes at 24 hr were kidney, abscess, stomach, and blood in descending order. In case of 188Re-IgG, high uptake at 4 hr post injection appeared on kidney, blood, abscess and stomach (3.92+/-0.62, 1.32+/-0.08, 0.88+/-0.01, 0.26+/-0.06, respectively). The upatkes at 24 hr were kidney, abscess, blood abd stomach in descending order. The abscess to blood uptake ratio of 99mTc-IgG was 0.5 at 4 hr and 2.02 at 24 hr and that of 188Re-IgG was 0.67 and 1.29. CONCLUSION: 99mTc-IgG and 188Re-IgG and 188Re-IgG canbe labeled efficiently with direct labeling method. However, 99mTc-IgG and 188Re-IgG, labeled with direct method, was unstable. Further study in needed to enhance the stability of the antibody labeling.
Abscess
;
Animals
;
Humans
;
Immunoglobulin G
;
Kidney
;
Mercaptoethanol
;
Rats
;
Stomach
6.Hypotensive Efficacy and Safety of Manidipine on the Patient with Essential Hypertension.
Won Sang YOO ; Young Bin JEON ; Sang Hyun PARK ; Chang Young LIM ; Suck Koo CHOI
Korean Circulation Journal 1991;21(2):350-355
Thirty patient with essential hypertension were administered Manidipine, a new calcium antagonist, 10~20mg once daily to evaluate the hypotensive efficacy and safety for 8 weeks. And the followings were the result. 1) Patients were consists of 14 male, 16 female, aged 53 in average and classified as mild in 21 and moderate in 9 patients. 2) Optimum intial dose was 10mg and 10 to 20mg were the doses recommended. 3) Blood pressure dropped after 8 weeks 24/13mmHg in average, rewarding 80% effectiveness and normalized in 87%. 4) Most frequent side reaction was facial flushing in 5 patiens followed by palpitation and dizziness, all of which did not disturb the continuation of medication. 5) Most of routine laboratory parameter were normal and unchanged between before and after the trial. 6) Overall rating of usefulness was 77%. In conclusion, Manidipine 10 to 20mg once daily regimen is well tolerated and effective in the treatment of mild to moderate essential hypertension.
Blood Pressure
;
Calcium
;
Dizziness
;
Female
;
Flushing
;
Humans
;
Hypertension*
;
Male
;
Reward
7.Nasal reconstruction with various flaps: case report.
Jong Woo CHOI ; Sang Hun CHUNG ; Chong Kun LEE ; Sang Tae AHN ; Poong LIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(2):265-273
No abstract available.
8.Synthesis of Substrates for Gene Therapy Monitoring of HSV1-TK System.
Soon Hyuk AHN ; Chang Woon CHOI ; Sang Moo LIM ; Ok Doo AWH ; Tae Hyun CHOI
Korean Journal of Nuclear Medicine 2002;36(2):102-109
No abstract available.
Genetic Therapy*
9.A Case of WilsonMikity Syndrome.
Jae You CHOI ; Sang Ho CHOI ; Byung Hak LIM ; Im Ju KANG
Journal of the Korean Pediatric Society 1988;31(2):241-245
No abstract available.
10.Transthoracic-Extrapleural Approach for Microsurgical Thoracic Discectomy with Video Assistance: Technical Report of Three Cases.
Sang Ho LEE ; Sang Hyeop JEON ; Jong Yeul CHOI ; Ho Yeon LEE ; Byung Joo JUNG ; Sang Rak LIM
Journal of Korean Neurosurgical Society 2000;29(12):1677-1681
No abstract available.
Diskectomy*