No abstract available.
Irritable Bowel Syndrome*

No abstract available.
Irritable Bowel Syndrome*

BACKGROUND AND OBJECTIVES: Coronary collateral circulation is known to have beneficial effects in patients with angina pectoris and myocardial infarction. The purpose of this study is to determine the predictors of collateral vessels development, the pathways of collateral circulation and the changes in collateral flow after coronary intervention and its functional significance in patients with total occlusion. MATERIALS AND METHODS: One hundred thirty five patients who underwent coronary angiogram between Jan '97 and Dec '97 in Chonnam University Hospital (out of 3,264 cases) had total occlusion of one coronary artery were classified into two groups: angina pectoris (Group I:50 M, 19 F, 62.4+/-11.0 years) and acute myocardial infarction (Group II: 47 M, 19 F, 62.0+/-9.5 years). RESULTS: Among 135 patients, 123 patients had collateral circulation. Collaterals were more frequently observed and better developed (grade 2 or 3) in Group I than Group II. Proximal and ostial lesions were associated with well developed collaterals. Collateral circulation was more frequently observed and well developed in proportion to the duration of angina in Group I. In 123 patients with collateral circulation, 247 collateral circulations were observed. Right coronary artery (RCA) and Left circumflex coronary artery (LCX) were more frequent recipient arteries than left anterior descending coronary artery (LAD)(RCA:2.20+/-1.02, LCX:1.88+/-0.94, LAD:1.29+/-0.8 respectively, RCA vs. LAD:p<0.001, LCX vs. LAD:p=0.014). Coronary interventions were performed in 50 out of 135 patients, collateral flow of Group II decreased much more than Group I after intervention (Group I: 5/14, Group II: 24/36, p=0.046). The wall motion score was lower in patients with well developed than poorly developed collaterals (20.7+/-4.91 vs. 23.7+/-6.22, p=0.015). CONCLUSION: Proximal or ostial lesion and duration of angina are major predictive factors for the development of collateral circulation. Collateral circulation is associated with preserved myocardial contractility.After coronary intervention in patients with acute myocardial infarction, recruitment of preexisting collaterals may be more important mechanism rather than neoangiogenesis.
Angina Pectoris ; Arteries ; Collateral Circulation* ; Coronary Vessels* ; Humans ; Jeollanam-do ; Myocardial Infarction

No abstract available.
Korea*

This is a statistical observation based on data of deaths occurred in the first army group(1A) of Republic of Korea Army (ROKA) and data brought to Wonju Army Hospital for medicolegal autopsy by all of Military Police Corps (MPC) in 1A during the year of 1996. The report aims to reveal facts on various causes of death of military members in attempt to analyse 70 cases statistically and differences between military members and civillians. The following are the summary of results ; 1. The total numbers of death in 1A were 70 cases and autopsy rate was 17.1%(12 cases). All cases were males. 2. The violent deaths were 60 cases(85.7%) and the natural deaths were 10 cases(14.3%). 3. The percentage of deaths of soldiers was 81.4%(the most), sergeants was 8.6%, officers was 5.7%, others was 4.3%. The group of the private (25.7%) and the private first class (25.7%) was the leading group of death by the rank. 4. For deaths due to injuries, the percentage of deaths due to gunshut injury was 51.2%, traffic accident was 30.1%, explosion of bomb was 7.0%, fall was 7.0% and blunt injury was 4.7%. 6. For the natural deaths, 10 cases were recorded and death due to neoplasm was taking the most of the total percentage with 40%. 7. For the violent deaths, the percentage of accidental death was 42.4%, suicide was 40.7% and homicide was 16.9%. These results suggest that suicide by firearm and traffic accident including military owned vehicle could be the major cause of death in army, and intensive management for group of the private and the private first class could be important to reduce the number of death.
Accidents, Traffic ; Autopsy ; Bombs ; Cause of Death ; Explosions ; Gangwon-do ; Homicide ; Hospitals, Military ; Humans ; Male ; Military Personnel ; Police ; Republic of Korea ; Suicide ; Wounds, Nonpenetrating

The adult trematode, Fasciola hepatica and Eurytrema pancreaticum, employed in this experiment were obtained from the cattle slaughtered at the local abbatoir. The worms were selected and washed several times in normal sterilized saline solution. Each ten of intact F. hepatica and about thirty to fifty of E. pancreaticum were incubated in 50 cc volume of special incubation flasks with incubation medium consisting of 50 cc of Krebs-Ringer phosohate buffer (pH 7.4). The incubation medium was added C(14)-lactate and non-radioactive carrier Na-lactate so as to contain lactate concentration of 32 mg per cent. The worms were allowed to incubate for 3 hours in the Dubnoff metabolic shaking incubator at 38 C. After incubation period, respiratory CO(2) samples from central wall of incubation flask were analysed for total CO(2) production rate and their specific activity of respiratory CO(2). The lactate uptake rate was determined by analyzing the the difference between lactate concentration in a medium before and after the incubation period, and the pyruvate appearance rate was dertermined by analyzing the pyruvate concentration in a medium after incubation. The glycogen samples isolated from worms were analyzed for the tissue concentration and their radioactivities in order to determine the turnover rate of glycogen pool. Radioactivities of these serise of experiment were counted by an endwindow Geiger-Muller counter as an infinitely thin samples. The quantative analysis of C(14)-lactate utilized by F. hepatica and E. pancreaticum were summerized and compared as following. In F. hepatica the lactate uptake rate was a mean value of 1.04+/-0.15 micromole/hr/g of wet wt. and pyruvate apperance rate was a mean value of 0.132+/-0.005 micro-mole/hr/g of wet wt. The total CO(2) production rate by the flukes averaged 13.82+/-0.75 micro-mole/hr/g of wet wt. The relative specific activities of respiratory CO(2) showed a mean value of 9.93+/-0.62 per cent. The rate of CO(2) production derived from medium C(14)-lactate was a mean of 1.38+/-0.13 micro-mole/hr/g of wet wt. Therefore the averge value of 55.27+/-5.78 per cent (R.L.D. CO(2)) and 15.35+/-1.90 per cent (R.L.D. pyr) of lactate was oxidized into respiratory CO(2) and pyruvate respectively. On the other hand, in E. pancreaticum the lactate uptake rate was a mean value of 0.61+/-0.18 micromole/hr/g of wet wt, and pyruvate appearance rate was a mean of 0.023+/-0.001 micromole/hr/g of wet wt. The total CO(2) production rate by the E. pancreaticum averaged 4.29+/-0.85 micromole/hr/g of wet wt. The relative specific activity of respiratory CO(2) (R.S.A CO2) showed a mean value of 9.20+/-0.34 per cent. Thus, a mean value of 9.20 per cent of total CO(2) production rates was originated from C14-lactate in a medium, therefore the rate of CO(2) production derived from medium C(14)-lactate was a mean value of 0.40+/-0.10 micromole/hr/g of wet wt. The average value of 23.93+/-7.11 per cent(R.L.D. CO(2)) and 3.86+/-0.45 per cent(R.L.D. pyr) of lactate was oxidized into respiratory CO(2) and pyruvate respectively. The tissue concentration of glycogen in F. hepatica was a mean of 2.63 per cent/g of wet wt, while in E. pancreaticum was a mean of 4.06 per cent/g of wet wt. The turnover rate of glycogen pool in F. hepatica yielded a value of 0.073+/-0.008 micromole/hr/g of wet wt whereas in E. pancreaticum yielded only a mean of 0.006+/-0.002 mg/hr/g of wet wt. Therefore, the half time of glycogen turnover, which is the time interval required to replace the half of glycogen pool with medium C(14)-lactate, gave value of a mean of 10.73+_0.76 days in F. hepatica. However, incorporation of C(14)-lactate into glycogen was negligible in the E. pancreaticum. Theses data impressed that the carbohydrate such as lactate may play a role of major part of their oxidative metabolism in F. hepatica, whereas minor part of lactate participates in the oxidative metabolism in E. pancreaticum.
parasitology-helminth-trematoda ; Fasciola hepatica ; Eurytrema pancreaticum ; autoradiography ; biochemistry ; pyruvate ; lactate ; glycogen ; metabolism ; Krebs-Rigner phosphate buffer

BACKGROUND: The purpose of this study was to assess the prevalence of orthostatic hypotension(OH) and its associations with demographic characteristics, body mass index, medications, disease and activities of daily living. METHODS: Orthostatic hypotension was assessed at 1 minutes after the patients arose from a supine position among the 183 elderly patients aged 60 years or older in a mental hospital. RESULTS: The prevalence of orthostatic hypotension defined by changes in systolic or diastolic blood pressure was 41.0% and the prevalence of systolicorthostatic hypotension was 13.1%. Body mass index and serum sodium concentration were lower in women with orthostatic hypotension than those without orthostatic hypotension, but there were no differences among men. Orthostatic hypotension was significantly associated with the level of supine systolic and diastolic blood pressure. Through multiple logistic regression analysis, orthostatic hypotension seerned to be associated with factors such as body mass index, supine diastolic blood pressure and serum sodium concentration. There was no association between orthostatic hypotension and factors such as sex, age and medications. CONCLUSIONS: Orthostatic hypotension was common in the long-term hospitalized elderly patients. It was associated with hypertension, hyponatremia and low body weight.
Activities of Daily Living ; Aged* ; Blood Pressure ; Body Mass Index ; Body Weight ; Female ; Hospitals, Psychiatric ; Humans ; Hypertension ; Hyponatremia ; Hypotension ; Hypotension, Orthostatic* ; Logistic Models ; Male ; Prevalence ; Risk Factors* ; Sodium ; Supine Position

BACKGROUND: The purpose of this study was to assess the prevalence of orthostatic hypotension(OH) and its associations with demographic characteristics, body mass index, medications, disease and activities of daily living. METHODS: Orthostatic hypotension was assessed at 1 minutes after the patients arose from a supine position among the 183 elderly patients aged 60 years or older in a mental hospital. RESULTS: The prevalence of orthostatic hypotension defined by changes in systolic or diastolic blood pressure was 41.0% and the prevalence of systolicorthostatic hypotension was 13.1%. Body mass index and serum sodium concentration were lower in women with orthostatic hypotension than those without orthostatic hypotension, but there were no differences among men. Orthostatic hypotension was significantly associated with the level of supine systolic and diastolic blood pressure. Through multiple logistic regression analysis, orthostatic hypotension seerned to be associated with factors such as body mass index, supine diastolic blood pressure and serum sodium concentration. There was no association between orthostatic hypotension and factors such as sex, age and medications. CONCLUSIONS: Orthostatic hypotension was common in the long-term hospitalized elderly patients. It was associated with hypertension, hyponatremia and low body weight.
Activities of Daily Living ; Aged* ; Blood Pressure ; Body Mass Index ; Body Weight ; Female ; Hospitals, Psychiatric ; Humans ; Hypertension ; Hyponatremia ; Hypotension ; Hypotension, Orthostatic* ; Logistic Models ; Male ; Prevalence ; Risk Factors* ; Sodium ; Supine Position

No abstract available.
Dementia* ; Primary Health Care*

No abstract available.
Hypertension, Pulmonary*