No abstract available.
Carcinoma, Renal Cell* ; Neoplasm Metastasis*

No abstract available.
Carcinoma, Renal Cell* ; Neoplasm Metastasis*

The trematode Paramphistomum cervi empolyed in this experiment was obtained from the reticulum of cattle slaughtered at the local abbatoir. The worms were selected and washed several times in normal sterilized saline solution. Each about ten of intact worms were incubated in 50 cc volume of special incubation flasks with incubation mixture consisting of 50 cc of Krebs-Ringer phosohate buffer (pH 7.4) to which were added universally labeled C(14)-glucose and non-radioactive carrier glucose concentration of 200 mg per cent. The worms were allowed to incubate for 3 hours in the incubator at 38 C. After incubation period, respiratory CO(2) samples from central wall of incubation flask were analysed for total CO(2) production rate and their specific activity of respiratory CO(2). Glycogen samples isolated from worms were analysed for the tissue concentration and their radioactivities in order to determine the turnover rate of glycogen pool. The glucose uptake rate was determined by analysing the difference of the glucose concentration in a medium before and after incubation period. Radioactivities of these series of experiments were counted by an endwindow Geiger-Muller counter as an infinitely thin samples. The quantitative analysis of C(14)-glucose utilized by Paramphistomum cervi was summerized as the following. The glucose uptake rate by Paramphistomum was a mean value of 2.32+/-0.27 micro-mole/hr/g of wet wt. and total CO(2) production rate by the worms averaged 10.85+/-0.41 micro-mole/hr/g of wet wt. The relative specific activities of respiratory CO(2) averaged 49.72+/-13.20 per cent. Thus, a mean of 49.72 per cent of total CO(2) production rate was originated from the glucose in the medium, therefore the rate of CO(2) production derived from medium glucose was mean of 5.24+/-2.16 micro-mole/hr/g of wet wt. Thus, the average value of 37.46+/-5.28 per cent of glucose utilized by the worms from the medium glucose was oxidized to respiratory CO(2). The tissue concentration of Paraphismum was a mean of 41.56+/-5.82 micro-mole/hr/g of wet wt or 4.16+/-0.72 per cent/g , and the turnover rate of glycogen pool yielded with a mean of 0.12+/-0.014 percent/hr or 0.06+/-0.04 mg/hr/g of wet wt. Therefore, a mean value of 16.75+/-4.84 per cent of glucose was incorporated to the glycogen. These data account for that at least 54.21 per cent of the utilized glucose by the worms participated in furnishing the oxidation into respiratory CO(2) and the synthetic process into glycogen. According to the above data of the experiment, it is suggested in the metabolic process of glucose by the Paramphistomum that the synthetic process into the glycogen is less active than the oxidative process into the resppiratory CO(2).
parasitology-helminth-trematoda ; Paramphistomum cervi ; autoradiography ; biochemistry ; glucose ; metabolism ; CO(2) ; glycogen

Cystic lesions of the adrenal are extremely rare. Pseudocysts (39% of all adrenal cysts) are the most common clinically detected cysts and result from hemorrhage into normal adrenal gland due to severe infection and trauma or adrenal neoplasm. Histologically, the lining of adrenal pseudocyst is not covered with epithelium and is composed of connective tissue. We are presenting a case of infected adrenal pseudocyst suffering from right lower chest and upper abdominal pain in a 35-year-old woman with brief review of the literatures.
Abdominal Pain ; Adrenal Gland Neoplasms ; Adrenal Glands ; Adult ; Connective Tissue ; Epithelium ; Female ; Hemorrhage ; Humans ; Thorax

PURPOSE: There are a variety of open surgical and endoscopic methods to the treatment of urethral injuries. The objective of our study is to evaluate the efficacy of primary endoscopic urethral realignment according to the injury site. MATERIALS AND METHODS: Twenty eight patients with urethral injuries(23 anterior and 5 posterior) were treated by primary endoscopic urethral realignment from March 1990 to August 1997. According to the injury site, age distribution, etiology of injury, associated injuries, time to operation, operating time, duration of urethral Foley catheterization, maximal flow rate, postoperative complications and treatment of post-realignment stricture were reviewed. RESULTS: The age range of our patients was from 20 to 86 years(mean 45.0). Among the 28 patients, 23 were anterior and 5 were posterior urethral injuries. Pelvic bone fracture was associated in 1 patient(20.0%) in the anterior urethral injury group, while 5 patients(100%) in the posterior urethral injury group. The mean time after injury to realignment was 1.9 days (range 0 to 9) and the mean operating time was 53.9 minutes in the anterior urethral injury group(range 20-190) and 79.0 minutes in the posterior urethral injury group(range 25-170). The mean duration of urethral Foley catheterization was 24.5 days in the anterior urethral injury group and 61.4 days in the posterior urethral injury group. The mean maximal flow rate after catheter removal was 31.4ml/sec in the anterior urethral injury group and 24.6ml/sec in the posterior urethral injury group. Of the 23 patients, 9 patients(39.1%) had post-realignment strictures in the anterior urethral injury group and 8 were treated with visual urethrotomy, and only one patient was required open urethroplasty. Of the 5 patients, 4 patients(80.0%) had post-realignment strictures in the posterior urethral injury group and treated with visual urethrotomy. CONCLUSIONS: Primary endoscopic urethral realignment is a safe and simple technique with minimal mobidity regardless of injury site. The stricture formation, impotence and incontinence rates of this technique are comparable to those reported for open surgical methods. Finally, most post-realignment strictures can be treated successfully with visual internal urethrotomy with or without occasional sound dilation.
Age Distribution ; Catheters ; Constriction, Pathologic ; Erectile Dysfunction ; Humans ; Male ; Pelvic Bones ; Postoperative Complications ; Urinary Catheterization

Diastasis of the ankle joint was associated with extensive ligamentous rupture and resulted from external rotation or abduction injuries at the ankle. It might occur without associated fracture but was more frequently seen in cases of bimalleolar fracture in which there was fracture of the medial malleolus or rupture of the deltoid ligament with fracture of the lower third of the fibula. Thirty patients of diastasis of the ankle joint were admitted and treated by internal fixation with screw and bolt from January 1978 to December 1981. The following results were obtained: 1. The main cause of the injuries was falling from a height and the other causes were slipping down and sports injury in order. 2. The most common type by Lauge-Hansen classification was supination-external rotation type (20 cases, 67%). 3. Partial diastasis of the ankle joint or anterior type was 14 cases (47%) and complete diastasis or total type was 16 cases (53%). 4. In all cases, mixed oblique fibular fracture and medial instability were seen. 5. The good results were achieved in 24 patients (80%).
Accidental Falls ; Ankle Fractures ; Ankle Joint ; Ankle ; Athletic Injuries ; Classification ; Clinical Study ; Fibula ; Humans ; Ligaments ; Rupture

PURPOSE: Premature ejaculation is the most common male sexual disorder, affecting perhaps as many as 75% of men, but its cause has not been well established. The objective of this study is to evaluate whether alcohol injection on the dorsal aspect of the penis can induce a desensitization of penile sensory nerve fiber in rats. MATERIALS AND METHODS: Forty-four male Sprague-Dawley rats were divided into 4 groups. Group I of 4 rats, the control group, did not undergo any procedure. Group II of 8 rats, received only an alcohol injection without electrical stimulation. In group III of 4 rats, only electrical stimulation was performed without alcohol injection. In group IV of 28 rats, all rats received an alcohol injection on the dorsal aspect of the penis, and groups of four rats were sacrificed after electrical stimulation on the glans penis at 1, 2, 4, 7, 10, 14, and 21 days after alcohol injection. Spinal cords were sectioned and processed for immunohistochemical staining for c-Fos protein. RESULTS: No c-Fos protein was detected in the normal control group, and either none or few c-Fos protein positive neurons were seen in the alcohol injection only group. The number of c-Fos protein positive neurons in the electrical stimulation only group was 30.25+/-3.53 cells/section. Four days after alcohol injection, the level of c-Fos protein positive neurons was reduced significantly compared with the control group (p<0.05), and was very close to the control group at 10 days after alcohol injection. CONCLUSIONS: Our study demonstrates that alcohol injection in the dorsal aspect of the penis reduces c-Fos protein positive neurons in the spinal cord segment through desensitization of penile sensory nerve fibers.
Animals ; Electric Stimulation ; Humans ; Male ; Nerve Fibers ; Neural Conduction* ; Neurons ; Penis ; Premature Ejaculation ; Rats* ; Rats, Sprague-Dawley ; Spinal Cord

Usually in the subtotal gastrectomy, the left and the right gastric arteries, as well as the left and the right gastroepiploic arteries are ligated. Thus, to avoid a blue stomach surgeons preserve the spleen and the short gastric arteries. When a radical subtotal gastrectomy with splenectomy is performed, meticulous caution is necessary; otherwise, the subtotal gastrectomy might have to be changed to a total gastrectomy to prevent a blue stomach. We report the case of a 67-year-old woman who had distal stomach cancer with a splenic solitary mass, for which splenic meatastasis could be excluded. We planned and performed a laparoscopy-assisted radical subtotal gastrectomy with splenectomy as the diagnostic and therapeutic option. In this case, to avoid a remnant stomach infarction or total gastrectomy we saved the left gastric artery and vein with clearing perivascular soft tissue, lymphatics, and lymph nodes. Thus the radical therapeutic goal was reached, and serious complications were avoided.
Aged ; Arteries ; Female ; Gastrectomy* ; Gastric Stump ; Gastroepiploic Artery ; Humans ; Infarction ; Lymph Nodes ; Spleen ; Splenectomy* ; Stomach Neoplasms* ; Stomach* ; Veins

Transcatheter closure of secundum atrial septal defect(ASD) with a "buttoned" double-disk device is feasible, effective and safe method as an alternative to surgical closure. Stretched diameter of ASD, determined by balloon sizing is generally used as a guide to prediction of success or selection of device size used for transcatheter closure of ASD. To test whether other non-invasive assessment of ASD size can provide an alternative method for a stretched diameter, we studied the relationship between various measures of ASD in 22 adult patients with ASD. Although transthoracic echocardiographic horizontal or vertical diameter of ASD, the maximal diameter of ASD measured at operation and pulmonary-to systemic flow ratio(Qp : Qs), the stretched diameter had no significant correlation with other measurements. It is conclused that other assessments of ASD size can not be used as adjuncts in the estimation of the stretched ASD diameter, which in turn can be used for prediction of success or selection of device size for occlusion of the ASD.
Adult* ; Echocardiography ; Heart Septal Defects, Atrial* ; Humans

PURPOSE: The superficial spreading type of early gastric cancer (SSE) has unique features such as its growth pattern and histologic aggressiveness. But its incidence rate is very low, so the clinicopathologic features of SSE are not well known. The aim of this study is to clarify the clinicopathologic features of the superficial spreading type of gastric cancer and we propose an appropriate treatment strategy with the proper treatment modality. METHODS: A retrospective study was conducted on 894 surgically resected patients with early gastric cancer. The superficial spreading type was defined as a lesion more than 20 cm(2). The demographic features and histopathological features were analyzed by using the hospital records. The survival rate was analyzed by the Kaplan-Meier method and the other statistics were analyzed using the chi-square test. RESULTS: For the superficial and common groups, there were no significant differences in the rates of submucosal layer invasion, the histologic types and differentiation and the tumor location. But the ratio of lymph node metastasis was significantly different (P<0.05). There were some differences concerning the operative methods between the groups. For the superficial spreading type, the portion of total gastrectomy was greater than that of the common type. The average distance between the upper portion of the tumor and the proximal resection margin was shorter for the superficial spreading type than that for the common type (3.78+/-2.79 cm vs 5.58+/-2.79 cm, respectively). The 5 year survival rate and the recurrence rate between the two types were not significantly different. CONCLUSION: Because of the higher rate of lymph node metastasis and the higher rate of an indistinct tumor margin, wide resection with adequate lymph node dissection (D1+beta or more) seems to be a proper operative method for the superficial spreading type of early gastric cancer.
Gastrectomy ; Hospital Records ; Humans ; Incidence ; Lymph Node Excision ; Lymph Nodes ; Neoplasm Metastasis ; Recurrence ; Retrospective Studies ; Stomach Neoplasms ; Survival Rate