1.Problems in Humeral Interlocking with Seidel Nail
Koing Woo KWUN ; Sin Kun KIM ; Sang Wook LEE ; Chang Hyuk CHOI ; Jin Kun LEE
The Journal of the Korean Orthopaedic Association 1996;31(2):199-204
Seidel nail is one of locked humeral nail and Seidel himself reported excellent result in his preliminary report using his nail. But our early experience showed disappointing result with high rate of complications, So we reviewed our 16 cases of humeral shaft fracture with polytrauma treated with Seidel nail and studied anatomical fitness of the nail within the distal medullary space using CT scan. The most frequent complication was intraoperative fracture of the proximal humerus < 4 cases> and this seemed to be due to lateral placement of pilot hole. There were 3 cases of nonunion and these cases showed insufficient distal anchorage, either primarily or postoperatively. Anatomical fitness study showed insufficient spreading of nail flanges in 5 cases of distal canal width below 9mm and nonunion cases were in this group. Other problems of Seidel nail were technical difficulties due to occasionally incorrect proximal targeting device and frequent breakage of adaptor screw. Study of more cases may be needed to confirm the design problem of Seidel nail.
Humerus
;
Multiple Trauma
;
Tomography, X-Ray Computed
2.A familial case of tricho-rhino-palangeal syndrome.
Kyong Ok KO ; Sang Hyun BYUN ; Jong Jin SEO ; Kun Su RHEE ; Young Hun CHUNG ; Yong Bae SIN
Journal of the Korean Pediatric Society 1992;35(8):1135-1140
No abstract available.
3.A Case of Neuromyelitis Optica with Paraneoplastic Syndrome in Hepatocellular Carcinoma.
Hyun Kyung KIL ; Gu Eun LEE ; Hyuk Jin HONG ; Sang Jong PARK ; Sang Kun SIN
Journal of the Korean Ophthalmological Society 2013;54(10):1630-1634
PURPOSE: We report a case of neuromyelitis optica (Devic's syndrome) with hepatocellular carcinoma. CASE SUMMARY: A 70-year-old male with hepatocellular carcinoma presented with bilateral visual loss. A relative afferent pupillary defect was not observed in either eye due to bilateral mydriasis. On brain MRI, there was no specific finding, however, on spine MRI, multiple and severe myelopathies were observed. After high-dose methylprednisolone pulse therapy, the visual acuity was 0.03 in the right eye and counting fingers at 30 cm in the left eye. CONCLUSIONS: We encountered a case of neuromyelitis optica involving bilateral optic neuropathy in hepatocelluar carcinoma. Therefore, in patients with an optic neuropathy of uncertain etiology, clinicians should consider performing a systemic evaluation.
Aged
;
Brain
;
Carcinoma, Hepatocellular*
;
Eye
;
Fingers
;
Humans
;
Male
;
Methylprednisolone
;
Mydriasis
;
Neuromyelitis Optica*
;
Optic Nerve Diseases
;
Optic Neuritis
;
Paraneoplastic Syndromes*
;
Pupil Disorders
;
Spinal Cord Diseases
;
Spine
;
Visual Acuity
4.A Case of Polymyositis associated with Hepatitis B infection.
Sang Kun SIN ; In Soo JOO ; Byung In HAN ; Ji Man HONG ; Seong Yul JOO ; Jang Hee KIM
Journal of the Korean Neurological Association 2002;20(3):315-317
Polymyositis(PM) is one of idiopathic inflammatory myopathy, characterized by proximal muscle weakness, myalgia and muscle enzyme elevation. Currently the main pathogenesis is well documented, the cell-mediated immunity. We experienced a case of polymyositis associated with hepatitis, developed after hepatitis B virus(HBV) infection. This virus-induced autoimmunity seems to result from the cross-reactivity between muscle protein and B-viral antigen, so called antigenic mimicry. This relation of PM and HBV is more significant in Korea because of the epidemicity of HBV infection.
Autoimmunity
;
Hepatitis B virus
;
Hepatitis B*
;
Hepatitis*
;
Immunity, Cellular
;
Korea
;
Molecular Mimicry
;
Muscle Proteins
;
Muscle Weakness
;
Myalgia
;
Myositis
;
Polymyositis*
5.Lethal Catatonia in the Right Middle Cerebral Artery Territory Infarction.
Ji Man HONG ; Sang Kun SIN ; Oh Young BANG ; Kyoon HUH ; In Soo JOO
Journal of the Korean Neurological Association 2003;21(3):307-310
Lethal catatonia is a rare and fatal clinical syndrome. It has diverse etiologies, both functional and organic. We experienced a man with left hemiplegia and striking catatonia. Brain imaging showed a large right hemispheric infarction and hypoperfusion. Symptoms and signs of catatonia were markedly improved after treatment of dopa-agonist and benzodiazepine. This case suggests that right hemispheric infarction could be a possible cause of lethal catatonia, and supports earlier clinical literature relating catatonia and the parietal lobe.
Benzodiazepines
;
Catatonia*
;
Hemiplegia
;
Infarction*
;
Middle Cerebral Artery*
;
Neuroimaging
;
Parietal Lobe
;
Strikes, Employee
6.Simultaneously Measured CO2 Reactivity in the Basilar and Middle Cerebral Artery: The Utilization of Power M-mode Doppler and Anterior-posterior Probes Fixating Device.
Ji Man HONG ; Dong Hoon SHIN ; Kyoon HUH ; In Soo JOO ; Sang Kun SIN ; Seung Nam LEE
Journal of the Korean Neurological Association 2007;25(1):75-80
BACKGROUND: Studies using a transcranial Doppler (TCD) to establish cerebral vasoreactivity (CVR) have mostly focused on the anterior circulation. The purpose of this study is not only to evaluate the feasibility of the power motion mode Doppler (PMD) with a probes fixating device, but also to simultaneously measure the CVR between the middle cerebral artery (MCA) and the basilar artery (BA) during hypercapnea simulated by the rebreathing technique. METHODS: Twenty eight healthy volunteers were enrolled. Baseline hemodynamic values (heart rate, blood pressure) were measured while volunteers sat in a comfortable position for 5 minutes. The TCD was performed in two steps. First, velocities and spectra of the MCAs were simultaneously monitored. Then, the velocities and spectra of the MCA and BA were simultaneously monitored by a headset that included an anterior-posterior probes fixating device. The equation for CVR was ([maximum mean velocity baseline mean velocity] x 100/baseline mean velocity). RESULTS: Baseline mean velocities were revealed as follows: (64.0+/-13.7, 65.0+/-11.9 cm/s in right and left MCA; p>0.05; 67.3+/-12.2, -45.3+/-7.6 cm/s in dominant MCA and BA). CVR did not differ between the dominant MCA and the BA (46.1+/-12.1, 46.0+/-15.1%; p>0.05), nor between the right and left MCAs (46.9+/-15.2, 46.4+/-14.8%; p>0.05). There was a positive linear correlation between the CVR of the dominant MCA and that of the BA (r=0.856; p<0.001). CONCLUSIONS: PMD with a probes fixating device for accurate insonation is a useful tool for evaluating the relative CVR between the MCA and BA. Our study suggests that CVR values of the BA are similar to those of the MCA.
Basilar Artery
;
Healthy Volunteers
;
Hemodynamics
;
Middle Cerebral Artery*
;
Volunteers
7.The Clue for Early Diagnosis and Prediction of Intracranial Involvement in Rhinocerebral Mucormycosis.
Ji Man HONG ; Byung In HAN ; Sang Kun SIN ; Oh Young BANG ; Jang Sung KIM
Journal of the Korean Neurological Association 2002;20(5):467-474
BACKGROUND: Rhinocerebral mucormycosis (RCM) is an uncommon and fatal clinical syndrome resulting from an opportunistic infection caused by a fungus of the order Mucorales in immunocompromized patients. The mortality and morbidity in the patients with intracranial involvement is invariably high, and it was reported that most survivors had early diagnosis and received aggressive treatment. Therefore, we retrospectively reviewed four patients of pathologically confirmed mucormycosis to find out the clues for early diagnosis of RCM and for prediction of fatal intracranial involvement. METHODS: The clinical, radiological features and histo-pathological involvement sites in the patients with intracranial involvement were compared to those without intracranial involvement. RESULTS: All the patients had uncontrolled diabetes and were admitted with orbital involvement. On the precise physical examination, mucosal involvement was found in all patients; three of them in only nasal mucosa and one in oral palatal mucosa. Despite the vigorous antifungal therapy, two patients had intracranial involvement and expired. MRI finding of extensive sphenoid sinusitis adjacent cavernous sinus preceded the intracranial involvement of RCM, which was not found in the patients without intracranial involvement. CONCLUSIONS: Our findings suggest that early observation of oral or nasal mucosal changes might be an important clinical clue for differentiation of RCM from other causes of rhino-oculo-cerebral symptoms in uncontrolled diabetic patients, and that extensive sphenoid sinusitis might be an important radiological feature for predicting the fatal intracranial involvement of RCM.
Cavernous Sinus
;
Diabetes Mellitus
;
Early Diagnosis*
;
Fungi
;
Humans
;
Magnetic Resonance Imaging
;
Mortality
;
Mucorales
;
Mucormycosis*
;
Mucous Membrane
;
Nasal Mucosa
;
Opportunistic Infections
;
Orbit
;
Physical Examination
;
Retrospective Studies
;
Sphenoid Sinus
;
Sphenoid Sinusitis
;
Survivors
8.A Case of Gliomatosis Cerebri; MRI and MR Spectroscopy Findings.
Jae Hyuk LEE ; Sang Kun SIN ; Sung Yeol JOO ; Jae Ho HAN ; Oh Young BANG ; In Soo JOO ; Kyoon HUH
Journal of the Korean Neurological Association 2003;21(3):320-322
No abstract available.
Magnetic Resonance Imaging*
;
Magnetic Resonance Spectroscopy*
;
Neoplasms, Neuroepithelial*
9.Hepatic Intraarterial Chemotherapy in Unresectable Hepatic Metastases of Colorectal Cancer.
Jin Cheon KIM ; Han Il LEE ; Chang Sik YU ; Hee Won CHUNG ; Sang Wee KIM ; Jeong Sin LEE ; Kun Choon PARK
Journal of the Korean Cancer Association 1997;29(2):227-234
PURPOSE: Unresectable hepatic metastases of colorectal cancer does not seem to be amenable to the various treatment modalities. We modified hepatic intraarterial chemotherapy by different installation of port and regimen. MATERIALS AND METHODS: Between July 1989 to December 1995, 27 patients of colorectal cancer with unresectable liver metastases were randomly allocated into either hepatic intraarterial (HA, 11 patients) or systemic intravenous (IV, 16 patients) chemotherapy after primary tumor resection. Chemo-port was installed with preservation of hepatic arterial flow. One cycle of HA regimen included 5-fluorouracil (5-FU) and mitomycin-C (MMC) with or without leucovorin (LV) for 14 days every month. The IV regimen included 5-FU and LV for 5 days every month. Both HA and IV chemotherapy were continued from 6 to 12 cycles. RESULTS: The response exceeding partial remission was experienced in six patients (55%) among 11 patients in the HA group, while only two (13%) patients showed response among sixteen patients in the IV group. One year survival was not different between two groups. Although lethal toxicity was not found, patients showed marked increase of the performance scale (ECOG) in both groups. CONCLUSION: Although survival benefit was not prominent, higher response rate with tolerable complication was found in the HA group. Prudent selection of effective drugs and combination of systemic chemotherapy are needed to improve the survival with minimal complication.
Colorectal Neoplasms*
;
Drug Therapy*
;
Fluorouracil
;
Humans
;
Leucovorin
;
Liver
;
Mitomycin
;
Neoplasm Metastasis*
10.A Study for Incidence of Childhood Leukemia in Kyongnam Province, Korea.
Soon Yong LEE ; Kwang Yong PARK ; Geun Ha CHI ; Myung Jin KO ; Tae Jin YANG ; Sang Kyu PARK ; Byeung Kyu PARK ; Sang Duk KIM ; Ki Hong PARK ; Young Tak LIM ; Young Ho LEE ; Jae Sun PARK ; Hee Young SIN ; Chul Joo LYU ; Hacki Ki KIM ; Kun Soo LEE ; Jeong Ok HAH ; Heung Sik KIM ; Tai Ju WHANG ; Jin Ho CHUN
Korean Journal of Pediatric Hematology-Oncology 2001;8(1):27-34
PURPOSE: Of the cancers in childhood, leukemia is the most frequent one. For the desirable control of childhood leukemia, the basic data for the incidence has a great importance. The authors made a report about the incidence of leukemia in childhood, which analyzed the data from 126 cases in Kyongnam province, Korea, during 1991~1995. METHODS: The data were obtained from 126 new cases of childhood leukemia who had been living in the Kyongnam province and were diagnosed at the 26 university hospitals or general hospitals in the Kyongnam area and other cities from 1991 to 1995. RESULTS: The age-and-sex adjusted annual incidence rate per 100,000 population during 1991~1995 varied from 1.82 to 2.86, and cumulative annual incidence rate was 2.41 (male 2.26 and female 2.57 respectively). Male to female sex ratio was 1:1 in total cases. By the major types of childhood leukemia, the cases were composed of acute lymphocytic leukemia 70.6%, acute myelocytic leukemia 26.9% and chronic myelocytic leukemia 2.5%. The cumulative annual incidence rate per 100,000 population (crude rate) during 1991~1995 were 2.77 in Ulsan city, 2.62 in Chinju city and 2.34 in the whole area of Kyongnam province. CONCLUSION: It was concluded that the age-and-sex adjusted annual incidence rate per 100,000 of childhood in Kyongnam province was 2.41, which was lower than that in Pusan city in the same period. And, there was no significant difference of the cumulative annual incidence rate between Ulsan area and Chinju area in the same period.
Busan
;
Female
;
Gyeongsangnam-do*
;
Hospitals, General
;
Hospitals, University
;
Humans
;
Incidence*
;
Korea*
;
Leukemia*
;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
;
Leukemia, Myeloid, Acute
;
Male
;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
;
Sex Ratio
;
Ulsan