1.IS6110 based DNA Fingerprinting of Mycobacterium tuberculosis Isolated from The Nationwide Tuberculosis Prevalence Survey in 1995.
Sang Jae KIM ; Young Kil PARK ; Sang Hyun CHO ; Gil Han BAI ; Yeun KIM
Journal of the Korean Society for Microbiology 1998;33(5):475-484
One hundred and thirty-eight strains of Mycobacterium tuberculosis isolated from the 7th nationwide tuberculosis prevalence survey in 1995 were subjected to the restriction fragment length polymorphism (RFLP) analysis using IS6110 probe to define the representative fingerprinting patterns of Korean strains of M. tuberculosis and to evaluate the usefulness of DNA fingerprinting in tracing the transmission link of M. tuberculosis. Among 138 strains, 129 different IS6l10 RFLP types were identified. The number of bands in IS6110 RFLP types diversed from 1 to 20, and the majority (75%) was 9 to 14 bands. The RFLP patterns of 8 out of 15 strains isolated from the follow-up survey of one and half year later after the 7th national TB prevalence survey were unchanged when compared with previous RFLP patterns. Fifteen (11%) out of 138 strains were grouped in 6 IS6110 clusters; 2 with 10 copies, 2 with 12 copies, 1 with 14 copies, and 1 with 17 copies. These clusters were unable to be subclassified by IS1081 or (GTG) probes except one cluster by pTBN12 probe. The transmission links of 2 clusters were deducible; one from household and another from neighborhood, but those of remaining clusters were unclear because they had no contact one another. The results suggest that vigorous transmissions in tuberculosis are still progressing in Korea.
Dermatoglyphics
;
DNA Fingerprinting*
;
DNA*
;
Family Characteristics
;
Follow-Up Studies
;
Korea
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymorphism, Restriction Fragment Length
;
Prevalence*
;
Residence Characteristics
;
Tuberculosis*
2.A Case Report of Primary Aldosteronism with Sustained Hypertension After Adrenalectomy.
Sang Yung SUL ; Sang Kil PARK ; Won Rak CHOI ; Ki Hyun KIM ; Jong Seong KIM
Korean Circulation Journal 1986;16(3):411-415
We experienced a case of primary aldosteronism due to adrenal adenoma. The patient was 45-year old female, whose main complaints were weakness, headache, and fatigue. By use of abdominal CT scan, ultrasonogram, adrenal angiogram and by result of clinical laboratory findings, we conculuded the diagnosis of adrenal adenoma, and confirmed it by surgical and pathologucal findigs. The clinical sympyoms disappeared after left adrenalectomy, and laboratory findings of renin, aldosterone, electrolutes were normalized but hypertension persisted, so she has been managed by antihypertensives.
Adenoma
;
Adrenalectomy*
;
Aldosterone
;
Antihypertensive Agents
;
Diagnosis
;
Fatigue
;
Female
;
Headache
;
Humans
;
Hyperaldosteronism*
;
Hypertension*
;
Middle Aged
;
Renin
;
Tomography, X-Ray Computed
;
Ultrasonography
3.Primer directed amplification of mycobacterium tuberculosis DNA in clinical specimens I. primers and reaction conditions.
Sang Jae KIM ; Young Kil PARK ; Sang Hyun CHO ; Myung Sup SHIM
Journal of the Korean Society for Microbiology 1992;27(1):35-44
No abstract available.
DNA*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
4.Primer directed amplification of mycobacterium tuberculosis DNA in clinical specimens I. primers and reaction conditions.
Sang Jae KIM ; Young Kil PARK ; Sang Hyun CHO ; Myung Sup SHIM
Journal of the Korean Society for Microbiology 1992;27(1):35-44
No abstract available.
DNA*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
5.The size comparison of the diameter of anterior segmental bronchus and that of anterior segmental artery.
Sang Jin KIM ; Yeon Hyeon CHOE ; Kil Sun PARK ; Dae Young KIM
Journal of the Korean Radiological Society 1992;28(4):541-544
It is thought to be reliable roentgenologic sign of pulmonary plethora that the diameter of anterior segmental artery(d-ASA) is larger than that of anterior segmental bronchus(d-ASB). To evaluate the reliability of this sign, we compared d-ASA with d-ASB on chest rentgenograms of 100 normal adults. Of the total 105 cases. d-ASA was larger than d-ASB in 40 cases (38.1%), smaller than d-ASB in 34 cases(32.4%) and equal to (d-ASA and) d-ASB in 31 cases(29.5%). The ratio(ABR) and difference between d-ASA and d-ASB ranged from 0.70 to 1.58(mean, 1.05±0.30) and from -1.85mm to +2.45mm(mean of absolute value, 0.75mm±0.57). These results showed that the relationships between d-ASA and d-ASB were variable. Conclusively, d-ASA may be larger than d-ASB in even normal adults and mild degree of pulmonary plethora cannot exectly evaluated with this findings only.
Adult
;
Arteries*
;
Bronchi*
;
Humans
;
Thorax
6.Antituberculosis Drug Resistance in Korea , 1998-1999.
Gill Han BAI ; Young Kil PARK ; Hyang Kyu LEE ; Sang Jae KIM
Journal of the Korean Society for Microbiology 2000;35(5):368-368
No Abstract Available.
Drug Resistance*
;
Korea*
7.PNS CT in Symptomatic Patients without Mucosal Abnormality: The Relationship between Anatomic Variations and Symptomas.
Hyun Yang LIM ; Noh Kyoung PARK ; Kil Jun LEE ; Seok TAE ; Sang Chun LEE
Journal of the Korean Radiological Society 1994;30(3):459-464
PURPOSE: The purpose of the study is to investigate the correlation between the symptoms and the incidence of anatomical variant without mucosal abnormality. MATERIALS AND METHODS: Out of 892 patients with CT performed for the evaluation of sinus disease symptoms between March 1991 and March 1993, we observed the anatomic variations in 82 symptomatic patients without mucosal abnormality(male:female=43:39, mean age 36. 4 years). The control group included 88 patients with facial bone CT performed for the evaluation of trauma during the same period while patients with recent paranasal sinusitis were excluded. (male:female=76:12, mean age 22. 4 years). The scouis were performed with 5-ram section thickness from posterior margin of sphenoid sinus to anterior margin of posterior ethmoid and then with 3 mm thickness from anterior margin of posterior ethmoid to anterior margin of frontal sinus. The artatomic variations included nasoseptal deviation, concha bullosa, Hailer cells, Agger nasi cells, etc. RESULTS: The anatomic variations were demonstrated in 71 our of 82 symptomatic patients(86. 5%), whereas they were seen 26 of 88 patients(29. 5%) in control group. CONCLUSION: Our data suggest that there is a possible causal relationship between anatomic variations and symptomas. Even though without accompaning mucosal abnormalities, anatomic variations could contribute simply to its symptomas. ^natomic variants may obstruct or narrow the airway, leading to turbulating air flow or interrupting ucociliary movement, and finally may produce a series os symptoms.
Facial Bones
;
Frontal Sinus
;
Humans
;
Incidence
;
Sinusitis
;
Sphenoid Sinus
8.A Case Report of Slipped Capital Femoral Epiphysis Associated with Hypogonadism and Diabetes Insipidus
Keun Woo KIM ; Sang Lim KIM ; Chong Wha PARK ; Kil Yeong AHN
The Journal of the Korean Orthopaedic Association 1988;23(3):911-916
The slipped capital femoral epiphysis is the condition in which the femoral head slips downward and backward on the femoral neck at the epiphyseal plate. The underlying cause of this disease is unknown. In general, it is believed that endocrine factors may play a part as shown in experimental work. But few endocrine abnormalities have been proved. It is rare in Korea and eight cases have been reported and only one case was associated with diabetes insipidus in hypogonadal Turner mosaicism. Authors report a case of mild, acute on chronic slipped capital femoral epiphysis in a 19 year old male with hypogonadism and diabetes insipidus. It was treated by internal fixation with three Steinmann pins and the result was good.
Diabetes Insipidus
;
Femur Neck
;
Growth Plate
;
Head
;
Humans
;
Hypogonadism
;
Korea
;
Male
;
Mosaicism
;
Slipped Capital Femoral Epiphyses
9.Computed tomographic findings of intracranial tuberculoma
Sang Kil LEE ; Young Keun PARK ; Seung Ro LEE ; Heung Suk SEO ; Chang Kok HAHM
Journal of the Korean Radiological Society 1984;20(2):226-232
Intracranial tuberculomas have been reported occasionally, especially in Asia, though much decreased in recentyears. Those lesions can be diagnosed more easily and acurately using CT than conventional method, including angiography. Authors analysed CT findings of 21 cases, confirmed as tuberculoma, at Hanyang University Hospital from May 1979 to June 1983. The resuslts were as follows; 1. Of all 21 cases, multiple lesions were seen in 14 cases (67%) and single in 7(33%). 2. Of all 21 cases, lesions located only at supratentorial were in 19 cases(90%) and remained 2(10%) had lesions at both supra and infratentorial area. And temporal and parietal lobes were common location (65%) of all lesions. 3. In precontrast scan, density of tuberculoma showed largely isodense (68%)and others were slight high (29%) and low(3%). 4. All lesions were enhanced showed as homogeneous nodular (68%),ring-shaped(29%) and target shaped(3%). 5. All rings were continuous and thickness was largely uniform(67%), anddensity of center of the ring was mainly low(67%). 6. Edema was seen in 58% of all lesions: comparing with thesize of tuberculoma, edema size was smaller in 50%, lager in 33% and almost the same in 17%.
Angiography
;
Asia
;
Edema
;
Methods
;
Parietal Lobe
;
Tuberculoma
;
Tuberculoma, Intracranial
10.Gastroesophageal Reflux Disease
The Korean Journal of Gastroenterology 2019;73(2):70-76
Gastroesophageal reflux disease (GERD) is a condition that develops when reflux of stomach contents causes troublesome symptoms and/or complications. The prevalence of GERD is increasing worldwide and in Asia-Pacific. The latest Korean guidelines for GERD were published in 2012, and several international guidelines and consensus statements for the management of GERD have also been recently published. Here, we review these guidelines and consensus statements in order to provide a better understanding of the diagnosis and treatment of GERD.
Consensus
;
Diagnosis
;
Gastroesophageal Reflux
;
Gastrointestinal Contents
;
Prevalence