Neurilemmoma is usually a solitary nerve sheath tumor, most often seen in adults. Tl: neurilemmomas of the oral cavity have been reported to develop on the tongue, buccal m7; Cosa, palate, gingiva, floor of the mouth, and lower lip, in order of frequency. We describe 7-year-old boy witlf an asymptomatic, solitary neurilemmoma on his upper lip with a brit: review of the literature. Neurilemmoma should be considered as one of the tumors that ca develop on children's lips.
Adult ; Child ; Gingiva ; Humans ; Lip* ; Male ; Mouth ; Neurilemmoma* ; Palate ; Tongue

A 2-month-old female infant presented with a bluish-black, flat, hairy patch, 1.2cm in diameter, on the posterior aspect of her neck since birth. Histologic sections from the lesion showed numerous diffusely scattered dermal melanocytes throughout the dermis. The histopathologic and clinical findings were not fully oonsistent with any other known dermal melanocytosis. The diagnosis of “hairy blue nevus” was proposed for this unique lesion.
Dermis ; Diagnosis ; Female ; Humans ; Infant ; Melanocytes ; Neck ; Nevus, Blue* ; Parturition

Solitary morphea profunda is a rare form of scleroderma, characterized clinically by a solitary sclerotic plaque, and histologically by marked dermal and subcutaneous fibrosis with an inflammatory infiltrate. We describe another case of this entity presented with an ulcerative, indurated plaque on the left iliac crest, which histologically revealed a focal incidental acantholysis in the overlying epidermis and a marked eosinophilic infiltration through the dermis to the sub-cutaneous tissue.
Acantholysis* ; Dermis ; Eosinophils ; Epidermis ; Fibrosis ; Scleroderma, Localized* ; Ulcer

By light and scanning electron microscopy, the morphologies of Korean pubic louse(Phthirus pubis) were described and measured. Especially, electron microscopic structures of palpus, tuft organ, sensilla basiconicum and palpal lobe were reviewed in detail. The variations were obserbed in the number of dorsal setae and the setae of membranous processes of abdomen. And also, the importance of public health and epidemiological aspects was discussed.
Abdomen ; Microscopy, Electron, Scanning* ; Phthiraptera* ; Phthirus* ; Public Health ; Sensilla

We report herein a case of lymphomatoid papulosis in a 23-year-old female who had recurrent erythematous pinhead to pea sized papules and nodules on the both inner thighs and forearms for 4 years. Some lesions showed central hemorrhagic necrosis or scale formation. Individual lesions persisted for several months and showed spontaneous regression leaving pigmentation or depigmented atrophic scar. Histopathologically, there was marked cell infiltration, especially in the dermoepiderrnal junction and perivascular area. Infiltraled cells consisted of sorne ncutrophils and numerous atypical cells that had variable sized and irregular shaped nuclei. Electronmicroscopically, some atypical cells had cerebriform nuclei with marked peripheral condensation of chromatin and cytoplasm contained a few organelles, many polyribosomes and some dense bodies.
Chromatin ; Cicatrix ; Cytoplasm ; Female ; Forearm ; Humans ; Lymphomatoid Papulosis* ; Necrosis ; Organelles ; Peas ; Pigmentation ; Polyribosomes ; Thigh ; Young Adult

Acrokeratoelastoidosis of Costa is a rare palmoplantar keratoderma with autosomal dominant inheritance. It is clinically charaeterized by small, firm, yellowish, shiny, translucent papules occumng over the dorsal hands, the knuckles, and the lateral margine of the palms and soles. Histologically, the characteristic features are hyperkeratosis, aeanthosis, and most strikingly, fragmentation of coarse elastic fibers within the dermis. The lesions usually begin in early childhood and progress slowly. We herein report two familial cases of acrokeratoelastoidosis of Costa showing typical clinic1 and histopathological features.
Dermis ; Elastic Tissue ; Hand ; Keratoderma, Palmoplantar ; Wills*

Tegafur is a fluoropyrimidine structurally similar to 5-fluorouracil, used in the treatment of advanced gastrointestinal neoplasms. Mucocutaneous side reactions induced by this agent are rare and include photosensitivity of lichenoid and eczematous types, acral erythema, hyperpigmentation and palmoplantar keratoderma. However, to our knowledge, there has been no report of concurrent development of eruptions of two types in a patient. We describe a female patient with breast cancer, presented with combined features of acral erythema and hyperpigmentation due to oral tegafur.
Breast Neoplasms ; Erythema* ; Female ; Fluorouracil ; Gastrointestinal Neoplasms ; Humans ; Hyperpigmentation* ; Keratoderma, Palmoplantar ; Tegafur*

Anetoderma is loose and wrinkled skin lesions that show the characteristic histopathological feature of focal loss of elastic fibers in the dermis. The primary type of anetoderma arises in clinically normal skin and the secondary type replaces the lesions of associated disorders including various infections, infiammatory diseases and tumors. However, anetoderma due to pilomatricoma is very rare. Our patient, a 21-year-old female, presented with a soft and wrinkled skin overlying a firm, pedunculated tumor on her left upper arm. The histopathological examination showed anetodermic cutaneous changes which were associated with the underlying pilomatricoma.
Anetoderma* ; Arm ; Dermis ; Elastic Tissue ; Female ; Humans ; Pilomatrixoma* ; Skin ; Young Adult

Fifty-two cases of neurilemmoma, which occurred in the skin and soft tissue and filed at the Department of Clinical Pathology, Catholic University Medical College from 1974 to 1984, were included for the clinical study. Forty four cases whose microscopic slides were available were reviewed for the histopathologic observation. The results were as follows : Clinical observations 1) The average age of the patients was 42.8% years old, and the average duration of tlie tumor was 3.9 years. 2) Eight cases were acompanied with tenderness and cases with tingling sensation. Clinica] signs described prior to biopsy were palpable mass(15), slow growing mass (8), palpable cystic mass(6) and hard mass(4). 3) The mean diameter was 2.6m (0.45cm-8cm), and the frequent sites were head and neck (32.7%), upper extremities(28.8%), lower extremities (23.11%) and trunk (15.4%) in decreasing orders. Histopathologic observations 1) 33 cases were composed of both Antoni A and type B with variable composition, but only Antoni type A was observed in 6 cases and Antoni type B in 5 Cases. 2) On the areas of Antoni type B, there were several degenerative changes including cystic change (52.3%), hemorrhage(50%), hyalinization(27.3%), necrosis(25%), and calcification(4.5%). 3) In 3 cases out of 44, the tumor was observed in the dermis and the tumors composed of Antoni A only occurred on the tongue, neck, and upper arm.
Arm ; Biopsy ; Dermis ; Head ; Humans ; Lower Extremity ; Neck ; Neurilemmoma* ; Pathology, Clinical ; Sensation ; Skin ; Tongue

Eccrine spiradenoma is a txnign, painful tumor of the skin, which probably originates in the coil of the eccrine sweat glands and presents a characteristic clinical and pa.hological picture. However recently, the weakness and inconsistency of the enzymes histochemican, actions and electron microscopic findings, and the presence of numerous undifferentiated and indetirn, inate cells suggest a rather low degree of differentiation. We present herein four cases of eccrine spiradenoma which show livrse histopat.hologic characteristics including typical rosette-like structure, ductal structure, vacuar structure and mixed type, respectively. This report may support the premise that eccrine spiridinoma is defived not only from the eccrine duct but also from pluripotential stem cells.
Skin ; Stem Cells ; Sweat Glands