Twenty-five patients with cerebrovascular diseases were administered Nicardipine, a calcium antagonist, in daily dose of 60 mg per orally for 8-12 weeks during the year of 1983, to evaluate the efficacy of the drugs clinically. The following results were obtained. 1) General improvement rating was 80%. 2) Marked improvement(88%) were noted in subjective symptoms, especially of tinnitus, paresthesia and headache. significant improvement were noted in psychiatric(74%) and neurologic(71%) symptoms e.g disturbance of sleep, emotion, memory, speech, swallowing and muscle power. 3) In 13 hypertensive patients, average blood pressure lowered from 163/96 to 138/83 mmHg in 4 weeks and maintained thereafter. 4) major adverse effect was facial flushing, noted in 4 patients(16%), which were transient and mild and allowed to contiume medication.
Blood Pressure ; Calcium ; Deglutition ; Flushing ; Headache ; Humans ; Memory ; Nicardipine ; Paresthesia ; Tinnitus

No abstract available.
Wilms Tumor*

No abstract available.
Twins, Conjoined*

Thirty patient with essential hypertension were administered Manidipine, a new calcium antagonist, 10~20mg once daily to evaluate the hypotensive efficacy and safety for 8 weeks. And the followings were the result. 1) Patients were consists of 14 male, 16 female, aged 53 in average and classified as mild in 21 and moderate in 9 patients. 2) Optimum intial dose was 10mg and 10 to 20mg were the doses recommended. 3) Blood pressure dropped after 8 weeks 24/13mmHg in average, rewarding 80% effectiveness and normalized in 87%. 4) Most frequent side reaction was facial flushing in 5 patiens followed by palpitation and dizziness, all of which did not disturb the continuation of medication. 5) Most of routine laboratory parameter were normal and unchanged between before and after the trial. 6) Overall rating of usefulness was 77%. In conclusion, Manidipine 10 to 20mg once daily regimen is well tolerated and effective in the treatment of mild to moderate essential hypertension.
Blood Pressure ; Calcium ; Dizziness ; Female ; Flushing ; Humans ; Hypertension* ; Male ; Reward

No abstract available.
Humans ; Infant, Newborn*

No abstract available.
Thanatophoric Dysplasia*

No abstract available.
Diskectomy*

Ocular toxocariasis in human is a rare disease, which occurs by ingesting infective ova accidentally. Clinically, patients with ocular toxocariasis are divided into 3 groups: group 1 consisted of those with diffuse destructive endophthalmitis, group 2 included those focal posterior pole granuloma, group 3 was made up of those with peripheral inflammatory masses in a relatively quiet eye. We experienced a 17 year-old female whose left eye exhibited a dense white elevated inflammatory mass over the macular area and connective-tissue strands extending from the mass to vitreous and surrounding retina. We report this case with a review of literature, but we couldn't get the aid of the ELISA test for antibody of Toxocara canis.
Adolescent ; Endophthalmitis ; Enzyme-Linked Immunosorbent Assay ; Female ; Granuloma ; Humans ; Ovum ; Rare Diseases ; Retina ; Toxocara canis ; Toxocariasis*

The antihypertensive effects and serial changes of serum lipids were observed in 17 patients with essential hypertension, administered daily 30-60mg dose of Tripamide(Tripamol(R)) for 8 weeks. The results were as follows ; 1) After 8 weeks treatment, there is no change of serum total cholesterol, serum triglyceride and HDL-cholesterol were decreased by 3.2mg/dl(-1.9%) and 0.9mg/dl(-2.8%) respectively. The changes were not significant statistically. 2) After 8 weeks treatment, mean systolic and diastolic blood pressure were decreased by 11.2mmHg(-6.8%) and 7.7mmHg(-7.3%). 3) No significant side effect was observed during treatment except of 2 patients of mild headache and insomnia.
Blood Pressure ; Cholesterol ; Headache ; Humans ; Hypertension* ; Sleep Initiation and Maintenance Disorders ; Triglycerides

No abstract available.