The number of patients with tinea corporis diagnosed on the clinical findings and KOH examination was 1,709 during the five yea.rs between January 1976 and December 1980, representing l.5% of the total dermatologic out-patients of 105,267 examined at Chilgok Catholic Dermatological Clinic, Daegu, Korea. The annual number of patients with tinea corporis was 84 (0.47% of the total outpatients) in 1976,115 (0.6%) in 1977, and 263 (1.30%) in 1980, but the figure increased markedly in 1976 reaching 616 (2.51%) and 631 (2.89%) in 1980. Of the 1,709 patients, males numbered 793 and females 916. Although the age of peak incidence was in the third decade in both sexes, males outnumbered females slightly before age 19 and, as age advanced, female predominance became marked. The seasonal distribution of patients was interesting: in summer between June and September when the climate is very humid and hot, the incidence was markedly high. From the 1, 709 patients, 1,293 organisms composms of 6 species were isolated and identified. The species isolated were, in order of decreasing frequency, Trichophyton rubrum (622 organisms, 48. 1% of total organisms isolated), T. mentagrophytes (486 organisms, 36. 2%), Microsporum canis (147 organisms, 11. 4%), Epidermophyton floccosurn (29 organisms, 2.2%), M. gypseum (23 organisrns, l.8%) and T. ferrugineum (4 organisms, 0. 3%).
Climate ; Daegu ; Epidermophyton ; Female ; Humans ; Incidence ; Korea ; Male ; Microsporum ; Outpatients ; Seasons ; Tinea* ; Trichophyton

No abstract available.
Hepatitis B virus* ; Hepatitis B* ; Hepatitis*

No abstract available.
Hepatitis B virus* ; Hepatitis B* ; Hepatitis*

No Abstract Available.

PURPOSE: To evaluate the effect and safety of subconjunctival bevacizumab injection immediately after primary pterygium surgery. METHODS: From October 2010 to June 2011, 54 patients (54 eyes) with primary pterygium who had received pterygium excision with the bare sclera technique were evaluated. Twenty-seven patients (27 eyes) in the bevacizumab group received a subconjunctival injection of 5 mg (0.2 ml) bevacizumab and 27 patients (27 eyes) in the control group received a subconjunctival injection of 0.2 ml balanced salt solution immediately after surgery. At the 6-month follow-up, the degree of fibrovascular tissue proliferation, the recurrence rate of pterygium and the effect of wound healing were analyzed prospectively. RESULTS: One month after the surgery, the degree of fibrovascular tissue proliferation was inhibited in the bevacizumab group compared to the control group (p = 0.028). However, 3 to 6 months after surgery, there was no significant difference between the 2 groups. In addition, there was no significant difference between the 2 groups in the recurrence rate of pterygium and wound healing after surgery. CONCLUSIONS: Subconjunctival bevacizumab injection after primary pterygium surgery inhibited the degree of fibrovascular tissue proliferation for 1 month and safe for wound healing. Subconjunctival bevacizumab injection has the potential for adjunctive therapy after pterygium surgery.
Follow-Up Studies ; Humans ; Prospective Studies ; Pterygium* ; Recurrence ; Sclera ; Wound Healing ; Bevacizumab

Hyperkeratosis of the nipple and areola is a rare condition. We report a case of hyperkeratosis of the nipple and areola occurrinp in man with no underlying endocrirop thy or synthetic estrogenic drug therapy. The patient was not associated with epidermal nevus orichthyosis and so fitted into the nevoid form of hyperkeratosis of the nipple and areola. The clinical appearance and histological findings of the lesion were the same as those reported before. He showed a slight improvement in the color and hyperkeratcsis of the nipple and areola with 6 months use of a topical keratolytic agent and corticosteroid crearn.
Drug Therapy ; Estrogens ; Humans ; Nevus ; Nipples*

BACKGROUND: Many physiologic, pharmacologic and immunologic abnormalities were reported in atopic dermatitis but the cause and pathogenesis of the disease remain obscure. OBJECTIVE: This study was done to investigate the systemic immunologic abnormalities in atopic dermatitis. METHOD: To evaluate the cell mediated immunity, me quantified pei ipheral blood T lymphocytes and their subsets, using flow cytometery, and assessed plasma neopteiin levels by means of radioimmunoassay. To evaluate the abnormal humoral immunity, we assessed the serum IgE levels by means of enzyme-immunoassay. RESULTS: Mean proportions of peripheral blood T lymphocytes and, heir subsets in atopic Dermatitis patients were within normal limits. Hut the suppvessor/cytotoxic T lyrphocytes(T8) were significantly decreased in the group of se"ere atopic dermatitis compared with the group of mild atopic dermatitis(P<0.05). Plasma neopterin lervels in the group of atopic dermatitis were found to be significantly elevated as compared vith the control group(P<0.01), but no significant cifference was found between the mild and severe group of atcpic dermatitis(P>0.05). Mean serum IgE levels in the patients with atopic dermatitis were higher than reference value. But there was no significant difference between the mild and severe atopic dermatitis group. Serum IgE levels ivere negatiiely correlated with T8(r=-0.3774, P<0.05) and positively with T4/T8 ratio(r =0.5007, P<0.05). Conclusions : These data;uggest that the atopic der matitis has abr ormalities in cell mediated immunity as well as elevated IgE level.
Dermatitis, Atopic* ; Humans ; Immunity, Cellular ; Immunity, Humoral ; Immunoglobulin E ; Neopterin* ; Plasma* ; Radioimmunoassay ; Reference Values ; T-Lymphocyte Subsets* ; T-Lymphocytes

No abstract available.
Adult ; Biopsy ; Brain ; Child ; Deception ; Dermis ; Facial Bones ; Female ; Hair ; Humans ; Melanins ; Neurofibromatoses* ; Scalp ; Skin ; Temporal Muscle ; Zygoma

Two cases of clear cell syringoma are reported in the women who were 39 ad 54 years old, respectively. They had had asymptomatic, ricegrain-sized skin colored to yellowish pink papules on the face, particularly on he lower eyelid for several years. Interestingly, both of them had suffered from diabetes mellitus for more than a decade and been placed on irregular antidiabetic medications. Routine laboratory findings in the elder patient(case 2), unfortunately not checked in the younger patient(cases 1) due to her refusal, were within normal limits except marked glucosuria. Histologic examination revealed numerous various-sized, well-defined tumor nests composed largely of clear cells with polygonal cellular boundary and eccentric nucleus. Special stain with Periodic acid-Schiff disclosed existance of glycogen in the clear cells, but other special stains such as alcian blue showed negative findings. Electron microscopic examination of the elder patient revealed many multivesicular bodies suggestive of lysosomes, and numerous droplets of glycogen dispersed between them in villi-rich periluminal cell.
Alcian Blue ; Coloring Agents ; Diabetes Mellitus ; Disulfiram ; Eyelids ; Female ; Glycogen ; Humans ; Lysosomes ; Middle Aged ; Multivesicular Bodies ; Skin ; Syringoma*

We report two cases of proliferating trichilemmal cyst in a 61-ear-old woman and a 44-year-old woman who had a solitary tumor, on the left temporal area of the scalp and right flank, respectively. Histologically, the tumors were localized in the dermis and corisised of multilobulated cysts. The cyst walls were composed of liquamous epithelium showing trichilemmhl keratinization. Some of the cells had clear cytoplasm and were positive on PAS staining. Individiial cell keratinization, mild nuclear atypia were also found in the cyst walls. For the treatment, surgical excision was performed with sufficiert margin.
Adult ; Cytoplasm ; Dermis ; Epithelium ; Female ; Humans ; Scalp