This article reviewed the initial experiences of 73 cases of the magnetic resonance angiography (MRA) to evaluate its usefulness and limitaions as a screening examination. Among them 31 patients underwent correlative contrast angography (CA). MRA examinations were performed with 3-dimensional time of flight (TOF)acquisitions(carotid, intracranial vessels, abdomen & pelvis), 2-dimensional TOF (abdomen & pelvis), and 3-dimensional phase contrast (PC) method(intracranial vessels, lower extremity). In head and neck area, the success rates of MRA in visualization of normal vessels were 91% in the carotid artery and 89% in intracranial vessels. In comparison with correlative CA of 45 lesions in 23 patients, MRA show successful detection of abnormalities in 43 lesions. There was only one false positive case and one false negative case in differentiation of normal and abnormal cases. Among 43 lesions detected on MRA, 25 lesions were well correlated with CA but 18 lesions showed mild differences in degree of disease. In other areas, even thought for a limited number of cases, the abdominal aorta and proximal parts of its major branches were well visualized on MRA. In three cases of renal artery stenosis, MRA showed no visible renal artery in disease side. So the abnormality in renal artery could be suspected, but accurate stenotic site could not be detected. In three cases of arterial occlusion in pelvis and lower extremity, MRA were well correlated with CA. In conclusion, MRA can be used as an ideal safe screening examination method with high success rate and abnormality detection rate, especially in carotid artery, circle of Willis, main intracranial vessels, abdominal aorta and proximal portions of its major branches.
Abdomen ; Aorta, Abdominal ; Carotid Arteries ; Circle of Willis ; Head ; Humans ; Lower Extremity ; Magnetic Resonance Angiography* ; Mass Screening* ; Methods ; Neck ; Pelvis ; Renal Artery ; Renal Artery Obstruction

No abstract available.
Arthritis, Rheumatoid*

No abstract available.
Delivery of Health Care* ; Health Care Reform* ; Korea*

Peptide imaging is a new diagnostic modality in nuclear medicine. 111In-pentetreotide (OctreoscanR) is the first commercially available peptide radiopharmaceutical. This review article presents the RESULTS of previous studies using 111In-pentetreotide for several disease states, including neuroendocrine tumors, breast cancer and malignant lymphoma. The use of hand-held probe during surgery and the preliminary RESULTS of radiotherapy using radiolabeled somatostatin analogues are also reviewed. It can be concluded that somatostatin receptor scintigraphy is a promising diagnostic tool for localizing primary tumors that express receptors for somatostatin, staging secondary spread of tumor tissue, following up after therapy and identifying patients who may benefit from therapy with unlabelled or rediolabeled octreotide. The somatostatin receptor imaging will stimulate the development of new radiopharmaceuticals for other receptors and enhance the therapeutic use of radiolabeled peptides.
Breast Neoplasms ; Humans ; Lymphoma ; Neuroendocrine Tumors ; Nuclear Medicine ; Octreotide ; Peptides ; Radionuclide Imaging* ; Radiopharmaceuticals ; Radiotherapy ; Receptors, Somatostatin* ; Somatostatin*

Certine heavy metals which may lead peoples to poisonous status are widely used in industry and their used have been increasing along with rapid industrialization of this country. Such an increasement of metal uses aggravates the status of environmental pollution affecting foodstuffs which are the most important life supporting factor of animal and human being. Concerning the safety measures to minimize food-borne transmission of such hazardous metals, surveillance is the backbone of them and probably more so with a potential problem such as intoxication. Theoretically, this surveillance should include the determination of levels of heavy metal toxicants in foods, the determination of food consumption patterns and typical total diet, and the estimation of total load the metal contaminant from all sources of exposure including air, water, and occupational sources. In recent year, actually, such estimates on the total daily intake of some heavy metals from foods have been made in several developed countries and a wide variation of date by season, locality, and research method was recognized. Also in this country, this kind of research data is vitally needed to make up for the serious shortage or lack of references to estimate the total amount of heavy metal intake of the people. In this study, a modification model for estimation of the total daily intake of cadmium copper, nickel, zinc, and lead through foods was applied and concentrations of the above metals in crops cultivated in this country were measured with atomic absorption spectrophotometer to get the following results. 1.Level of heavy metal concentration in crops. Generally, the levels of such metals in essential crops such as rice, cucumber, radish, chinese cabbage, apple, pear, grape, and orange are similar or lower than those in Japan and other developed countries. By the way, a striking result on cadmium concentration was increasement of its concentration in rice from 0-0.035ppm in 1970 to 0.11ppm in this study. However, the value is still far below the Japanese Permissible Level of 1.0ppm. 2. Estimation of total daily intake per from foods. A new model for estimation was devised utilizing levels of metal concentration in food, amount of food consumed, and other food factors. Based on the above method, the daily intake of cadmium was estimate to be 70.53 microgram/man/day in average which was as high as the Limit Value of ILO/WHO(up to 71.4 microgram/man/day). Also, 3.89mg of Zinc, 1.65mg of cuppor, 0.32mg of lead were given as the total daily intake per capita by this research. 3. Efficacy of washing or skinning to decrease the amount of metals in crops. After washing the crops sufficiently with commercial linear alkylate sulfonate, the concentration of heavy metals could bae reduced to 50-80% showing decreasement rate of 20-50%. Also, after skinning the fruits, decreasement rate of the heavy metal concentration showed 0-50%.
Absorption ; Animals ; Asian Continental Ancestry Group ; Brassica ; Cadmium ; Citrus sinensis ; Copper ; Developed Countries ; Diet ; Environmental Pollution ; Fruit ; Humans ; Japan ; Metals ; Metals, Heavy ; Nickel ; Pyrus ; Raphanus ; Seasons ; Skin ; Strikes, Employee ; Vitis ; Water ; Zinc

Seperation anxiety disorder(SAD) is characterized by excessive anxiety about being apart from the individuals to whom a child is most attached. We noticed a case of a 13 year old boy's SAD with symptoms of nausea/vomiting, stomachache, school refusal, and severe weight loss. His mother was overanxious and overdependent but her'dependency was frustrated due to family problem. We investigated this case from a point of developmental aspect and family dynamics and tried to attempt therapeutic approach.
Anxiety Disorders* ; Anxiety* ; Child* ; Disulfiram* ; Humans ; Mothers ; Weight Loss*

One hundred ninety seven metatarsals of Korean adults were studied macroscopically for the number, position and direction of the diaphysial nutrient foramen. Most metatarsals had on diaphysial nutrient foramen which was situated in the middle third of the shaft with average foraminal index ranging from 43 to 51, but 73% of first metatarsals had two or more foramina. No foramen was observed in 3% of total metatarsals studied. Nutrient foramen was present most frequently on the lateral surface in the first and second metatarsals and on the medial surface in the fifth, but it was present about the same the rate on both medial and lateral surfaces in the third and forth. The direction of the foramen was toward the head in the first metatarsals and toward the basis in the rest being always away from the growing end, thus favoring the growing end theory.
Adult ; Head ; Humans* ; Metatarsal Bones*

No abstract available.
Carcinoma, Papillary* ; Thyroid Gland* ; Tretinoin*

M-mode echocardiography has been demonstrated to be a sensitive indicator of the sequential changes occurring in the heart in systemic arterial hypertension. The changes in function as well as anatomic features have been recorded. Previous analysis has focused on the anatomy and systolic function of the left ventricle, analysed in hypertensive heart disease. 13 normal subjects(Group I), 14 hypertensive patients without evidence of cardiac involvement(Group II) and 13 hypertensive patients with echocardiographic evidence of left ventricular hypertrophy(Group III) were compared using M-mode echocardiographic data and clinical. findings. The results are as follows : 1) Mean age are; Group I : 41 years(19-62), Group II : 49 years(25-67) and Group III : 53 years(30-83). There are no significant age difference between Group I and II. Sex ratio are 4:9, 8:6 and 7:6 respectively. 2) Mean arterial pressure are; Group I : 98+/-5mmHg, Group II : 126+/-7 mmHg and Group III : 131+/-101mmHg. 3) Left ventricular posterior wall thickness are; Group I : 0.87+/-0.12cm, Group II : 0.89+/-0.12cm and Group III : 1.32+/-0.18cm(p>0.05 in I vs II). 4) Left atrial dimension are; Group I : 2.77+/-0.68cm, Group II : 2.96+/-0.44cm and Group III: 3.12+/-0.60cm. 5) Left ventricular mass arel Group I : 194+/-51gm, Group II : 192+/-51gm and Group III : 318+/-77gm(p>0.05 in I vs II, p<0.001 in I vs II and II vs III). 6) Ejection fraction are; Group I : 0.57+/-0.09, Group II : 0.60+/-0.01 and Group III : 0.52+/-0.01)p>0.05). 7) Mitral valve EF solpe are; Group I : 113.70+/-23.26mm/sec, Group II : 81.14+/-17.22mm/sec and Group III : 69.92+/-22.70mm/sec(p<0.05 in I vs II, p<0.001 in I vs III and II vs III). 8) AEI are; Group I : 0.70+/-0.04, Group II : 0.56+/-0.07 and Group III: 0.48+/-0.07)p<0.001 in I vs II, I vs III and II vs III). From the above results, the atrial emptying index seems to be an early indicator of abnormalities of left ventricular diastolic compliance in hypertensive patients.
Arterial Pressure ; Compliance ; Echocardiography* ; Heart ; Heart Diseases ; Heart Ventricles ; Humans ; Hypertension ; Mitral Valve ; Sex Ratio

No abstract available.
Quality of Life*