1.Memory Impairment in Dementing Patients.
Sleep Medicine and Psychophysiology 1997;4(1):29-38
Dementia is defined as a syndrome which is characterized by various impairments in cognitive functions, especially memory function, Most of the diagnostic criteria for dementia include memory impairment as no essential feature. Memory decline can be present as a consequence of the aging process, But it does not cause significant distress or impairment in social and occupational functionings while dementiadoes. Depression may also be associated with memory impairment. funcitionings while dementiadoes. Depression may also be associated with memory impairment. However, unlike dementia, depression dose not cause decrease in delayed verbal learning and recognition memory. In dementia, different features of memory impairment may be present depending on the involved area. Memory impairment in cortical dementia is affected by the disturbance of encoding of information and memory consolidation, while memory imparnene in subcrotical denentiy is affected y the disturbance of retrieval in subcortial dementia.
Aging
;
Dementia
;
Depression
;
Humans
;
Memory*
;
Verbal Learning
2.A case of preconceptional transabdominal cervicoisthmic cerclage.
Moon Il PARK ; Ho Sang SEO ; Jai Auk LEE
Korean Journal of Perinatology 1993;4(2):162-166
No abstract available.
3.Metabolism of C(14)-glucose by Paramphistomum cervi.
Byong Seol SEO ; Han Jong RIM ; Sang Il LEE ; Dae Kwan PARK ; Sang Chan MOON
The Korean Journal of Parasitology 1965;3(1):5-9
The trematode Paramphistomum cervi empolyed in this experiment was obtained from the reticulum of cattle slaughtered at the local abbatoir. The worms were selected and washed several times in normal sterilized saline solution. Each about ten of intact worms were incubated in 50 cc volume of special incubation flasks with incubation mixture consisting of 50 cc of Krebs-Ringer phosohate buffer (pH 7.4) to which were added universally labeled C(14)-glucose and non-radioactive carrier glucose concentration of 200 mg per cent. The worms were allowed to incubate for 3 hours in the incubator at 38 C. After incubation period, respiratory CO(2) samples from central wall of incubation flask were analysed for total CO(2) production rate and their specific activity of respiratory CO(2). Glycogen samples isolated from worms were analysed for the tissue concentration and their radioactivities in order to determine the turnover rate of glycogen pool. The glucose uptake rate was determined by analysing the difference of the glucose concentration in a medium before and after incubation period. Radioactivities of these series of experiments were counted by an endwindow Geiger-Muller counter as an infinitely thin samples. The quantitative analysis of C(14)-glucose utilized by Paramphistomum cervi was summerized as the following. The glucose uptake rate by Paramphistomum was a mean value of 2.32+/-0.27 micro-mole/hr/g of wet wt. and total CO(2) production rate by the worms averaged 10.85+/-0.41 micro-mole/hr/g of wet wt. The relative specific activities of respiratory CO(2) averaged 49.72+/-13.20 per cent. Thus, a mean of 49.72 per cent of total CO(2) production rate was originated from the glucose in the medium, therefore the rate of CO(2) production derived from medium glucose was mean of 5.24+/-2.16 micro-mole/hr/g of wet wt. Thus, the average value of 37.46+/-5.28 per cent of glucose utilized by the worms from the medium glucose was oxidized to respiratory CO(2). The tissue concentration of Paraphismum was a mean of 41.56+/-5.82 micro-mole/hr/g of wet wt or 4.16+/-0.72 per cent/g , and the turnover rate of glycogen pool yielded with a mean of 0.12+/-0.014 percent/hr or 0.06+/-0.04 mg/hr/g of wet wt. Therefore, a mean value of 16.75+/-4.84 per cent of glucose was incorporated to the glycogen. These data account for that at least 54.21 per cent of the utilized glucose by the worms participated in furnishing the oxidation into respiratory CO(2) and the synthetic process into glycogen. According to the above data of the experiment, it is suggested in the metabolic process of glucose by the Paramphistomum that the synthetic process into the glycogen is less active than the oxidative process into the resppiratory CO(2).
parasitology-helminth-trematoda
;
Paramphistomum cervi
;
autoradiography
;
biochemistry
;
glucose
;
metabolism
;
CO(2)
;
glycogen
4.A Case of Congenital Hyperextension of the Knee.
Sang Chun LEE ; Hwan Il KIM ; Sang Ho BAEK ; Kil Seo KIM
Journal of the Korean Society of Neonatology 1998;5(1):72-76
Congenital dislocation of the knee is a very rare condition and was first described by Chatelaine in 1822. The etiology of this condition is unknown. It is generally subclassified as simple hyperextension, subluxation, and dislocation, depending on the degree of the joint displacement and the severity of disease. There are a large of associated conditions that have been described, the most common of which are congenital dislocation of the hip, club foot, arthrogryposis, and Larsen's syndrome. The mainstay of treatment is early serial rnanipulation and splinting. Operative treatment was indicated whenever conservative treatment did not lead to satisfactory reduction. The authors experienced a case of congenital hyperextension of left knee associated with the calcaneovalgus deformity of both foot. Early closed treatment obtanied a successful reduction and satisfactory knee motion.
Arthrogryposis
;
Congenital Abnormalities
;
Dislocations
;
Foot
;
Hip
;
Joints
;
Knee*
;
Splints
5.A Serial Rapist - Male Identification and Crime Scene Analysis in the Cases of a Serial Rapist.
Nam Soo CHO ; Seok Bean SONG ; Il Hyun PARK ; Sang Yong LEE ; Joong Seok SEO
Korean Journal of Legal Medicine 2005;29(1):47-51
The study presents the application of STR polymorphisms to male identification in the cases of a serial rapist in Korea. Since October 2000 a rapist from Cheongju city (a town located in central district) committed at least 36 rapes. DNA profiles obtained from semen stains, buccal cells and tongue tissue left at the scenes of crime and vaginal swabs of victims gave information that one and the same man had committed all the rapes. The Y-chromosome haplotype (12 loci) obtained was used for the identification process of rapist in mixed genotypes including victim's alleles. The crime scene data were referred from investigating police authorities described the relationship of victim to the offender, victim's age, time and place of sexual assault and rape locations. The behavioural analysis of crime scenes showed more similarities than differences for related crimes. These components were usually assessed in terms of proximity in time and space. Certain crime scene aspects of a serial rapist help identify components of offender spatial behaviour. As a result of this work, future research on the geography of rape and behavioural aspects of rapist will be directed towards those aspects of offences, which have been identified as relevant to the distance between an offender's base, and the site where he approached his victim.
Alleles
;
Chungcheongbuk-do
;
Coloring Agents
;
Crime*
;
Criminals
;
DNA
;
Genotype
;
Geography
;
Haplotypes
;
Humans
;
Korea
;
Male*
;
Police
;
Rape
;
Semen
;
Tongue
6.Case of rat mite dermatitis.
Hee Jae CHAE ; Sang Hyun CHO ; Baik Kee CHO ; Koo IL SEO ; Hee Chul EUN
Korean Journal of Dermatology 1993;31(1):99-104
We report three cases of rat mite dermatitis caused by Ornithonysus bacoti(Hirst, 1913), commonly referred to it as the tropicalrat mite. The first case, a 26-year old female had multiple pinhead sized vesicles with peripheral erythematous macule on the upper arms. The second case, a 34-year-old femal had multiple variable sized vesicles with erythematous base on the extremeties. The third case, a 43-year old male had multiple erythematous macules and papules with central punctum on the trunl: and extremities. Histopathologic sections from lesions of the first and second patient showed moderate perivascular lymphahistiocytic infiltration intermingled with some eosinophils. Causative mites, Ornithonyssus bacoti, female were collected around the skin lesion in rase 1, from the house dust in case 2 and furniture in case 3.
Adult
;
Animals
;
Arm
;
Dermatitis*
;
Dust
;
Eosinophils
;
Extremities
;
Female
;
Humans
;
Interior Design and Furnishings
;
Male
;
Mites*
;
Rats*
;
Skin
7.Treatment of Bone Tumor with Free Vascularized Bone Graft
Han Koo LEE ; Moon Sang CHUNG ; Sung Il BIN ; Byung Ho SEO ; Chong Suh LEE
The Journal of the Korean Orthopaedic Association 1987;22(2):493-504
In certain low-grade malignant tumors such as chondrosarcoma and giant cell tumor, radical treatments may provide a good chance for cure. And large bony defect after the radical treatment can be filled with the massive bone graft. Recent advances in clinical microsurgery have made free tissue transfer a clinical reality, and Taylor in 1975, first reported the technique of free vascularized fibula graft for the reconstruction of large tibial defects with excellent clinical results. We tried wide excision and free vascularized bone graft in 6 patients with malignant or aggressive bone tumor from April 1981 to November 1985 and followed up for more one year. Mean follow up of free vascularized bone graft is 26.4 months and that of devascularized bone graft is 22.6 months. The results of the free vascularized bone graft were compared with 10 patients who were treated with the wide excision and the devascularized bone graft. In this analysis, free vascularized bone graft is superior to devascularized bone graft in bony union, complications and functional results.
Chondrosarcoma
;
Fibula
;
Follow-Up Studies
;
Giant Cell Tumors
;
Humans
;
Microsurgery
;
Transplants
8.Hepatobiliary Manifestation of Inflammatory Bowel Disease
The Korean Journal of Gastroenterology 2019;73(5):248-259
The hepatobiliary system is one of the most common sites of extraintestinal manifestation in patients with inflammatory bowel disease (IBD). The progression of IBD can lead to a primary hepatobiliary manifestation and can occur secondary to multiple drugs or accompanying viral infections. Primary sclerosing cholangitis is the representative hepatobiliary manifestation of IBD, particularly in ulcerative colitis. Although most agents used in the treatment of IBD are potentially hepatotoxic, the risk of serious hepatitis or liver failure is low. The prevalence of HBV and HCV in IBD is similar to the general population, but the clinical concern is HBV reactivation associated with immunosuppressive therapy. Patients undergoing cytotoxic chemotherapy or immunosuppressive therapy with a moderate to high risk of HBV reactivation require prophylactic antiviral therapy. On the other hand, HCV has little risk of reactivation. Patients with IBD are more likely to have nonalcoholic fatty liver disease than the general population and tend to occur at younger ages. IBD and cholelithiasis are closely related, especially in Crohn's disease.
Cholangitis, Sclerosing
;
Cholelithiasis
;
Colitis, Ulcerative
;
Crohn Disease
;
Drug Therapy
;
Drug-Induced Liver Injury
;
Hand
;
Hepatitis
;
Hepatitis Viruses
;
Humans
;
Inflammatory Bowel Diseases
;
Liver Failure
;
Non-alcoholic Fatty Liver Disease
;
Prevalence
9.Hepatobiliary Manifestation of Inflammatory Bowel Disease
The Korean Journal of Gastroenterology 2019;73(5):248-259
The hepatobiliary system is one of the most common sites of extraintestinal manifestation in patients with inflammatory bowel disease (IBD). The progression of IBD can lead to a primary hepatobiliary manifestation and can occur secondary to multiple drugs or accompanying viral infections. Primary sclerosing cholangitis is the representative hepatobiliary manifestation of IBD, particularly in ulcerative colitis. Although most agents used in the treatment of IBD are potentially hepatotoxic, the risk of serious hepatitis or liver failure is low. The prevalence of HBV and HCV in IBD is similar to the general population, but the clinical concern is HBV reactivation associated with immunosuppressive therapy. Patients undergoing cytotoxic chemotherapy or immunosuppressive therapy with a moderate to high risk of HBV reactivation require prophylactic antiviral therapy. On the other hand, HCV has little risk of reactivation. Patients with IBD are more likely to have nonalcoholic fatty liver disease than the general population and tend to occur at younger ages. IBD and cholelithiasis are closely related, especially in Crohn's disease.
Cholangitis, Sclerosing
;
Cholelithiasis
;
Colitis, Ulcerative
;
Crohn Disease
;
Drug Therapy
;
Drug-Induced Liver Injury
;
Hand
;
Hepatitis
;
Hepatitis Viruses
;
Humans
;
Inflammatory Bowel Diseases
;
Liver Failure
;
Non-alcoholic Fatty Liver Disease
;
Prevalence
10.Isolated avuision fracture of the tibial attachment of the posterior cruciate ligament
Chil Soo KWON ; Kwang Yoon SEO ; Kil Dong CHANG ; Il Sang LEE
The Journal of the Korean Orthopaedic Association 1978;13(4):661-666
Five patients with isolated avulsion fracture of the tibial attachment of the posterior cruciate ligament were treated in our hospital from September, 1975 to May, 1978. Among the five patients. one was treated conservatively and the others by surgical repair using catgut suture, cancellous bone screw fixation and staple fixation. Four patients were followed from 4 to 10 months poatoperatively. Satisfactory results were obtained in four patients (one was loat in follow up).
Bone Screws
;
Catgut
;
Humans
;
Posterior Cruciate Ligament
;
Sutures