1.Cavernous Hemangioma of Lymph node: A case report with the review of literature.
Seong Nam KIM ; Sang Yong SONG ; Yong Il KIM
Korean Journal of Pathology 1992;26(5):496-499
Primary hemangioma of the lymph node is an extremely rare vascular neoplasm, and only four cases on the subject have been reported in the literature. We describe a case of cavernous hemangioma in an axillary lymph node that was incidentally found in 70-year-old woman who underwent a modified radical mastectomy for infiltrating duct carcinoma of the left breast. Brief review of the literature regarding vasoformative lesions occupying lymph node is made with special regard to differential diagnosis from reactive-proliferative processes and other true neoplasms.
Female
;
Humans
;
Diagnosis, Differential
;
Hemangioma
2.Electron Microscopic Study on Differentiation of Tracheal Epithelium in Human Fetus.
Sang Yong LEE ; Kwang Il NAM ; Sung Sik PARK ; Sang Yong LEE ; Kwang Il NAM ; Sung Sik PARK
Korean Journal of Physical Anthropology 1996;9(1):69-83
The human trachea is normally lined by a pseudostratified ciliated columnar epithelium where ciliated, goblet, intermediate and basal cells are mainly represented. However the fetal tracheal epithelium was found to be composed of ciliated, non-ciliated and basal cells. The present study was designed to characterize the development of ciliated cells in the fetal trachea at mid (19 weeks) and last (32 weeks) trimester of gestation. At 19 weeks of gestation, the tracheal epithelium, 35 µm in height, was composed of surface, intermediate and basal layers. The surface cells were subdivided into ciliated, immature ciliated, non-ciliated, granule containing and goblet cells. The ciliated cells covered approximately half of the luminal surface area. The immature ciliated cells contained basal bodies, but the apical membrane was not invested with cilia. The granule containing cells contained numerous dense granules, 0.3-0.7 µm in diameter, in the apical cytoplasm. The goblet cells contained less electron dense granules, 1-2 µm in diameter, in the apical cytoplasm. The cells in intermediate layer were relatively undifferentiated and contained poorly developed organelles. Submucosal gland were well differentiated and were composed of the mucous and serous cells. At 32 weeks of gestation, the tracheal epithelium, 50µm in height, was also composed of surface, intermediate and basal layer. The surface cells were composed of ciliated, non-ciliated and goblet cells. The ciliated cells, dominant type of surface cells, were subdivided into mitochondria-rich cells (type I) and smooth endoplasmic reticulum-rich cells (type II). The non-ciliated cell were of three subtypes : mitochondria-rich cells (type A), glycogen and microfilament-containing cells (type B) and cells with bulging apical surface into the lumen (type C). Small granule containing cell appeared in the basal layer. These cells contained clear vesicles, 50 ㎚m in diameter, and dense granules, 100-300 ㎚m in diameter. Submucosal gland were well developed and consisting of mucous, serous and myoepithelial cells. These results indicate that the cell populations of the tracheal epithelium at late stage of pregnancy have essential features similar to those of adult. and show that the different steps of ciliogenesis could be identified.
Adult
;
Basal Bodies
;
Cilia
;
Cytoplasm
;
Epithelium*
;
Fetus*
;
Glycogen
;
Goblet Cells
;
Humans*
;
Membranes
;
Organelles
;
Phenobarbital
;
Pregnancy
;
Trachea
3.Lymphokine-activated killer(LAK) cell activity in tumor-transplanted mice(I).
Sang Yun NAM ; Yun Tai LEE ; Young Il KIM ; Si Young KIM ; Kyung Sam CHO
Journal of the Korean Cancer Association 1991;23(2):218-229
No abstract available.
4.CT findings of orbital pseudotumor.
Min Yun CHOI ; Sang Hwa NAM ; Kun Il KIM ; Chang Hyo SOL ; Byung Soo KIM
Journal of the Korean Radiological Society 1992;28(3):327-331
To evaluate characteristic CT findings of orbital pseudotumor and to define differentialpoints from other pathology, the authors retrospectively reviewed CT of 19 patients who were prooen to have orbital pseudotumor by clinical course and, in some cases, biopsy. A variety of CT findings including extraocular muscle thickening(11 cases), streaky infiltration of retroorbital fat(11 cases), mass formation(10 cases), optic nerve thickening (6 cases), conjunctival thickening (5 cases), scleral thickening(4cases), enlarged lacrimal gland(4 cases) and destruction of orbital bone (2 cases) were observed. Thickening of the anterior portion and irregular margin were characteristic findings of extraocular muscle and optic nerve lesions. Mass formation predominantly occurs in the anterior portion of the orbit. In most cases more than two orbital structures are involved by lesion.
Biopsy
;
Humans
;
Optic Nerve
;
Orbit*
;
Orbital Pseudotumor*
;
Pathology
;
Retrospective Studies
5.A Case of Inherited Thymic Dysplasia Associated with Disseminated Cytomegalovirus Infection.
Seung Yeon NAM ; Mee Ae KANG ; Kang Mo AHN ; Young Jae KOH ; Sang Il LEE
Pediatric Allergy and Respiratory Disease 2000;10(2):171-176
No abstract available.
Cytomegalovirus Infections*
;
Cytomegalovirus*
6.Electrophysiological Studies in a Case of Friedreich's Ataxia.
Sang Am LEE ; Il Nam SUNWOO ; Ki Whan KIM
Journal of the Korean Neurological Association 1986;4(1):137-141
Observing a 16 years old male of classical Friedreich's ataxia with progressive ataxia, dysarthria, areflexia, loss of vibration and proprioception, Babinski sign, pes cavus, scoliosis, hyperglycemia, optic atrophy and hearing deficits, the nerve conduction studies and several evoked potential studies are performed. The sensory nerve potentials are markedly decreased in amplitude and the average technique has to be used to get the potentials, worse distally. The motor nerve functions, however, are normal. There is no consistent waves recorded on BAEP even with maximal stimulation bilaterally. VEP reveals prolonged latencies bilaterally but with normal amplitudes. On median nerve SEP stimulated at wrist, the amplitudes of potentials at Erb's point look decreased and no definite evoked potentials are recored at contralateral scalp. In contrast, the cervical evoked potentials are normal in amplitudes and latencies.
Adolescent
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Ataxia
;
Dysarthria
;
Evoked Potentials
;
Foot Deformities
;
Friedreich Ataxia*
;
Hearing
;
Humans
;
Hyperglycemia
;
Male
;
Median Nerve
;
Neural Conduction
;
Optic Atrophy
;
Proprioception
;
Reflex, Babinski
;
Scalp
;
Scoliosis
;
Vibration
;
Wrist
7.Diagnostic Sensitivity of Repetitive Nerve Stimulation Test in Myasthenia Gravis.
Sang Ahn LEE ; Ki Han KWON ; Il Nam SUNWOO
Journal of the Korean Neurological Association 1993;11(2):195-201
Repetitive nerve stimulation (RNS) test was systematically performed in proximal and distal muscles of 142 cases with myasthenia gravis (MG) and 45 norrnal controls and then analyzed qualitatively. Diagnostic sensitivity was 75% based on abnorrnal decremental response in at least one muscle. The sensitivity increased from 56% in ocular MG to 96% in type Iib MG according to severity of disease. Higher diagnostic yield was noted in the orbiculans oculi in ocular MG and in the trapezius in gereralized MG. RNS test on proximal muscle showed a higher positive rate than that on distal muscles. When distal muscle testing was negative, there was an additional increase of 24% in proximal muscle testing. The posttetanic exhaustion (PTE) enhanced diagnostic sensitivitY as much as 8% in generalized MG. The posttetanic facilitation(PTF) and PTE were observed in 50% and 38% of generalized MG and were most prominent in MG with moderate severity. Five patterns on RNS findings were classified according to test paramcters. The most common response was the pattern which showed normal arnplitude of compound muscle action potential, decremental response at low rate stimulation, and PTF without PTE.
Action Potentials
;
Muscles
;
Myasthenia Gravis*
;
Superficial Back Muscles
8.Lymphokine-activated killer(LAK) cell activity in tumor-transplanted mice(II).
Sang Yun NAM ; Yun Tai LEE ; Young Il KIM ; Si Young KIM ; Kyung Sam CHO
Journal of the Korean Cancer Association 1992;24(3):365-377
No abstract available.
9.A Serial Rapist - Male Identification and Crime Scene Analysis in the Cases of a Serial Rapist.
Nam Soo CHO ; Seok Bean SONG ; Il Hyun PARK ; Sang Yong LEE ; Joong Seok SEO
Korean Journal of Legal Medicine 2005;29(1):47-51
The study presents the application of STR polymorphisms to male identification in the cases of a serial rapist in Korea. Since October 2000 a rapist from Cheongju city (a town located in central district) committed at least 36 rapes. DNA profiles obtained from semen stains, buccal cells and tongue tissue left at the scenes of crime and vaginal swabs of victims gave information that one and the same man had committed all the rapes. The Y-chromosome haplotype (12 loci) obtained was used for the identification process of rapist in mixed genotypes including victim's alleles. The crime scene data were referred from investigating police authorities described the relationship of victim to the offender, victim's age, time and place of sexual assault and rape locations. The behavioural analysis of crime scenes showed more similarities than differences for related crimes. These components were usually assessed in terms of proximity in time and space. Certain crime scene aspects of a serial rapist help identify components of offender spatial behaviour. As a result of this work, future research on the geography of rape and behavioural aspects of rapist will be directed towards those aspects of offences, which have been identified as relevant to the distance between an offender's base, and the site where he approached his victim.
Alleles
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Chungcheongbuk-do
;
Coloring Agents
;
Crime*
;
Criminals
;
DNA
;
Genotype
;
Geography
;
Haplotypes
;
Humans
;
Korea
;
Male*
;
Police
;
Rape
;
Semen
;
Tongue
10.Quantitative Change of Repetitive Nerve StimulationTest in Myasthenia Gravis.
Ki Han KWON ; Sang Am LEE ; Il Nam SUNWOO
Journal of the Korean Neurological Association 1992;10(4):420-427
Repetitive nerve stimulation test (RNS) is an easy and non-invasive test which provides objective for the presence of a myasthenic neuromuscular defect and for monitoring possible improvement through various therapeutic measures, and makes the differentiation of neuromuscular junction disorders. Analysing the RNS test of 45 normal controls and 146 patients with myasthenia gravis quantitatively, the following results obtained. 1. At low rate stimulation, the decremental response upto 2 standard deviation in normal control are 7.1% in orbicularis oculi(~), 7.6% in flexor carpi ulnaris (FCU) and 5.4% in abductor digiti guinti muscle(ADQ). There are two kinds of facilitation noticed: incremental responses at repetitive low stimulation (13.3-14.9%) immediately after tetanic stimulationy and increased mean amplitudes of compound muscle action potentials after exercise(l3-17%). Four minutes after the tetanic stimulation, the decremental responses at low rate stimulation become accentuated slightly even in normal control group. 2. At low rate stimulation. There are singificant decremental decremental responses in patients with myasthenia gravis, but statistically no significant differences are seen in the quantity of decremental responses among 2, 3 and 5/sec rate of stimulation. 3. The pattern and severity of decremental responses at low rate stimulation are depending on the clinical type of generalized myasthenia gravis. There are no decremental responses in FCU or ADQ in ocular type. The decremental responses of oo are greater than that of FCU in mild generalize myasthenia, but the reverse is true in moderate generalized type. 4. Statistically significant post-tetanic facilitation and exhaustion are noticed in patients with generalized myasthenia gravis.
Action Potentials
;
Humans
;
Myasthenia Gravis*
;
Neuromuscular Junction Diseases