Malignant fibrous histiocytoma(MFH) is a high grade soft tissue sarcoma, commonly occur in the retroperitoneum, extremities, head and neck in the patient with old ages. But it is very uncommon that MFH primarily occurs in the lung, and uncommon in young ages. We experienced a young male patient with primary MFH of the lung. The patient had huge masses on both lungs which were diagnosed as MFH by thoracoscopy-guided wedge resection of mass, so we could not perform operative management. And we tried 6 cycles of chemotherapy using ifosfamide, doxorubicin, dacarbazine. After chemotherapy, masses still remained in spite of decreasing sizes.
Dacarbazine ; Doxorubicin ; Drug Therapy ; Extremities ; Head ; Histiocytoma ; Histiocytoma, Malignant Fibrous* ; Humans ; Ifosfamide ; Lung* ; Male ; Neck ; Sarcoma ; Thoracoscopy

OBJECTIVE: There has been a limited investigation looking into the correlation between pericardial fat and abdominal fat with coronary artery disease (CAD) as measured by coronary computed tomographic angiography (CCTA). We proposed that the volume of pericardial fat is larger in patients with CAD than in patients without CAD, and sought to determine which abdominal adiposity index best correlated with pericardial fat volume. METHODS: Participants were examined using CCTA between October 2007 and January 2008. All participants had no previous history of CAD. Pericardial adipose tissue (PAT) volume, abdominal total adipose tissue volume, abdominal subcutaneous adipose tissue volume, and abdominal visceral adipose tissue (AVAT) volume were measured using CCTA. RESULTS: Fifty patients (26.5%) demonstrated CAD, and 139 patients did not demonstrate CAD by CCTA. PAT volume in patients with CAD was larger than that of patients without CAD (173.2+/-64.2 cm3 vs. 147.6+/-50.4 cm3, p<0.01). However, indices of abdominal adiposity were not significantly different between the two groups. Using multivariable analysis, independent predictors of CAD were PAT volume (odds ratio [OR] 1.01, 95% confidence interval [CI] 1.00-1.02, p=0.04), coronary artery calcium score (OR 1.01, 95% CI 1.00-1.01, p<0.01), and typical chest pain (OR 4.88, 95% CI 1.47-16.21, p=0.01). AVAT volume showed a linear correlation with PAT volume. CONCLUSION: PAT volume was an independent predictor of CAD as measured by CCTA. PAT volume was also well correlated with the AVAT volume among the indices of abdominal adiposity.
Abdominal Fat ; Adipose Tissue ; Adiposity ; Angiography ; Calcium ; Chest Pain ; Coronary Artery Disease* ; Coronary Vessels ; Humans ; Intra-Abdominal Fat ; Subcutaneous Fat, Abdominal

PURPOSE: Completion thyroidectomy is the removal of any thyroid tissue that remains after less than total thyroidectomy. The purpose of the present study is to review the processes and pathologic results leading to completion thyroidectomy, and to determine the degree of increased morbidity with completion thyroidectomy. METHODS: The hospital records of 60 patients treated from January 1981 to December 2000 were retrospectively reviewed. RESULTS: The subjects were 48 women and 12 men with ages ranging from 17 to 72 years (mean 46.3 years). Initial pathologic results were 46 cases of papillary carcinoma (76.6%), 12 of follicular carcinoma (20%), one of medullary carcinoma and one of Hurthle cell carcinoma. Initial operations were lobectomy in 51 cases, bilateral subtotal thyroidectomy in 6 and enucleation in 3. Completion thyroidectomies were performed due to tumor recurrence in 32 cases, confirmed malignancy following permanent sections in 21 and others in 7. Twenty-one of the cases were performed within 6 months after initial operations. Residual or recurrent carcinoma was found in 36 cases of the completion thyroidectomy specimens (60%). Postoperative complications were as follows: transient and permanent recurrent laryngeal nerve palsy occurred in 1 (1.7%) and 2 (3.3%) cases, respectively, transient and permanent hypoparathyroidism occurred separately in 15 (25%) and 4 (6.7%) cases, respectively, and there was one case of hematoma (1.7%) and one of wound infection (1.7%). There was no correlation between complications and the interval between initial surgery and reoperation. CONCLUSION: Completion thyroidectomy could be performed with minimal morbidity and might prevent the development of regional recurrence by eliminating an unsuspected focus of cancer. The surgeon should not feel obligated to perform a total thyroidectomy if the diagnosis of cancer is not secure, because the second stage operation can be performed over a wide time interval, allowing the physician and patient considerable latitude for decision making.
Carcinoma, Medullary ; Carcinoma, Papillary ; Decision Making ; Diagnosis ; Female ; Hematoma ; Hospital Records ; Humans ; Hypoparathyroidism ; Male ; Postoperative Complications ; Recurrence ; Reoperation ; Retrospective Studies ; Thyroid Gland ; Thyroid Neoplasms* ; Thyroidectomy* ; Vocal Cord Paralysis ; Wound Infection

A 27-year-old female visited outpatient clinic for the evaluation of palpitation and dyspnea on exertion. Echocardiographic examination including transthoracic and transesophageal echocardiography revealed coarctation of aorta, bicuspid aortic valve, mitral valve prolapse, and sealed-up ventricular septal defect. Further evaluation with computed tomography angiography revealed another combined congenital anomaly of left isomerism with polysplenism and interrupted inferior vena cava and pulmonary embolism with deep vein thrombosis. After corrective surgery for the coarctation, she received anticoagulation therapy for the treatment and the secondary prevention of pulmonary embolism.
Adult ; Ambulatory Care Facilities ; Angiography ; Aortic Coarctation* ; Aortic Valve ; Bicuspid ; Dyspnea ; Echocardiography ; Echocardiography, Transesophageal ; Female ; Heart Septal Defects, Ventricular ; Humans ; Isomerism* ; Mitral Valve Prolapse ; Pulmonary Embolism ; Secondary Prevention ; Vena Cava, Inferior* ; Venous Thrombosis

A primary thyroid lymphoma is rare among all types of thyroid malignancy. Usually, a thyroid lymphoma is associated with underlying chronic autoimmune thyroiditis. Recently, we experienced a primary thyroid mucosa-associated lymphoid tissue(MALT) lymphoma, with an incidental micropapillary thyroid carcinoma, but lacking evidence of autoimmune thyroiditis. A female patient visited our hospital for further evaluation of a rapidly enlarging, painless thyroid mass which had been stable for 8 years. Lymphocytic thyroiditis or a lymphoma was suspected from fine needle aspiration performed at another hospital. The thyroid function test and other routine laboratory tests were normal. The histopathological findings after a total thyroidectomy revealed a MALT lymphoma with a micropapillary thyroid carcinoma. There was no evidence of chronic autoimmune thyroiditis. This is, to the best of our knowledge, the first case report of a MALT lymphoma arising from the thyroid gland without evidence of chronic autoimmune thyroiditis in Korea
Biopsy, Fine-Needle ; Female ; Humans ; Korea ; Lymphoma ; Lymphoma, B-Cell, Marginal Zone* ; Thyroid Function Tests ; Thyroid Gland* ; Thyroid Neoplasms ; Thyroidectomy ; Thyroiditis, Autoimmune*

A primary thyroid lymphoma is rare among all types of thyroid malignancy. Usually, a thyroid lymphoma is associated with underlying chronic autoimmune thyroiditis. Recently, we experienced a primary thyroid mucosa-associated lymphoid tissue(MALT) lymphoma, with an incidental micropapillary thyroid carcinoma, but lacking evidence of autoimmune thyroiditis. A female patient visited our hospital for further evaluation of a rapidly enlarging, painless thyroid mass which had been stable for 8 years. Lymphocytic thyroiditis or a lymphoma was suspected from fine needle aspiration performed at another hospital. The thyroid function test and other routine laboratory tests were normal. The histopathological findings after a total thyroidectomy revealed a MALT lymphoma with a micropapillary thyroid carcinoma. There was no evidence of chronic autoimmune thyroiditis. This is, to the best of our knowledge, the first case report of a MALT lymphoma arising from the thyroid gland without evidence of chronic autoimmune thyroiditis in Korea
Biopsy, Fine-Needle ; Female ; Humans ; Korea ; Lymphoma ; Lymphoma, B-Cell, Marginal Zone* ; Thyroid Function Tests ; Thyroid Gland* ; Thyroid Neoplasms ; Thyroidectomy ; Thyroiditis, Autoimmune*