The authors experienced a case of juvenile type cervical arteriovenous malformation. It was apoplectic in onset and represented spastic quadriparesis, sensory impairment and voiding difficulty. The authors treated with total excision of voluminous malformed vessels with good results.
Arteriovenous Malformations* ; Muscle Spasticity ; Quadriplegia

Cerebral rete mirabile is an entity of particular disease which showed the specific angiographic findings. Many authors have been reported this disease with various discussion in opinion. It's exact pathogenesis and etiology were however unable to establish. Authors had experienced a total of 10 cases with cerebral rete mirabile from 3 period of 1973 to 1977, which were confirmed by cerebral angiography. We attempted to analyze it clinically and discussed with the review of literature. The result were summarized as following; 1) In age and sex distribution, 8 patients were over 20 years old age and 2 cases were below 20. 7 cases were female and 3 male. 2) Majority of cases(8 of 10 cases) were accompanied with subarachnoid hemorrhage and only 2 cases were non-hemorrhagic which all were over 20 years. 3) In 8 cases with subarachnoid hemorrhage initial symptoms were mainly impairment of consciousness and signs of meningeal irritation such as headache and vomiting etc. Other common initial symptoms in both non-hemorrhagic and hemorrhagic cases were hemiparesis, speech disturbance and seizure. 4) All cases disclosed the characteristic angiographic findings of cerebral rete mirabile. A patient showed nonfilling of left carotid system and anomaly of left vertebral artery. Aneurysm of anterior communicating artery was combined in other case. It is our consideration that vertebral angiography must be helpful in this disease to demonstrate the collateral circulation and an abnormal findings of vertebrobasilar system.
Aneurysm ; Angiography ; Arteries ; Cerebral Angiography ; Collateral Circulation ; Consciousness ; Female ; Headache ; Humans ; Male ; Paresis ; Seizures ; Sex Distribution ; Subarachnoid Hemorrhage ; Vertebral Artery ; Vomiting ; Young Adult

Eleven cases of paragonimus brain abscess which were surgically treated from 1975 to 1978 were reviewed. All patients received supplementary bithionol therapy. Ten patient's clinical condition improved. Only one patient died due to post operative wound infections.
Bithionol ; Brain Abscess* ; Brain* ; Humans ; Paragonimus* ; Wound Infection

OBJECTIVE: To compare the slot-scan digital radiography (SSDR) of the lower extremity region and the computed radiography (CR) method with respect to the image quality and radiation exposure. MATERIALS AND METHODS: We enrolled 54 patients who underwent both the SSDR and CR of the lower extremities. The study evaluated and statistically compared the image quality of four features (outer cortex, inner cortex, trabeculae and intermuscular fat) at six different levels (pelvis, hip, femur, knee, tibia and ankle) between each method. The image quality was evaluated using a visibility scale, and the entrance skin dose was measured using a dosimeter at three different levels of a phantom (hip, knee, and ankle). RESULTS: The mean image visibility scale values for the SSDR method were significantly higher than for the CR method. The entrance skin dose for the SSDR method was 278 micro Gy at each level, compared to the entrance skin doses of the CR method, which were 3,410 micro Gy for the hip, 1,152 micro Gy for the knee, and 580 microGy for the ankle. CONCLUSION: Both the image quality and patient entrance skin dose data suggest that the SSDR method is superior to the CR method for the lower extremity musculoskeletal examination.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Lower Extremity/*radiography ; Male ; Middle Aged ; Radiation Dosage ; *Radiographic Image Enhancement/methods ; *Tomography, X-Ray Computed/methods ; Young Adult

In this study, we observed the alteration of choline signal intensity in hippocampus region of the depressive rat model induced by forced swimming test (FST). The purpose of this study was to evaluate the antidepressant efficacy in the depressive animal model using MR spectroscopy. Fourteen experimentally naive male Sprague-Dawley rats weighting 160~180 g were used as subjects. Drug injection group was exposed to the FST except for control group. The drugs were administered subcutaneously (SC) in a volume equivalent to 2 ml/kg. And three injections were administered 23, 5, and 1 h before beginning the given test. 1H MR spectra were obtained with use of a point resolved spectroscopy (PRESS) localization sequence performed according to the following parameters: repetition time, 2500 ms; echo time, 144 ms; 512 average; 2048 complex data points; voxel dimensions, 1.5x2.5x2.5 mm3; acquisition time, 25 min. There were no differences in NAA/Cr and Cho/Cr ratio between the right and the left hippocampus both normal control rats and antidepressant-injected rats. Also, no differences were observed in NAA/Cr and Cho/Cr ratio between the normal control rats and the antidepressant-injected rats both the right and the left hippocampus. In this study, we found the recovery of choline signals in the depressive animal model similar to normal control groups as injecting desipramine-HCl which was antidepressant causing anti-immobility effects. Thus, we demonstrated that MR spectroscopy was able to aid in evaluating the antidepressant effect of desipramine-HCl.
Animals ; Choline ; Hippocampus ; Humans ; Magnetic Resonance Spectroscopy ; Male ; Models, Animal ; Protons ; Rats ; Rats, Sprague-Dawley ; Spectrum Analysis ; Swimming

PURPOSE: This study aims to investigate the actual compliance with chemotherapy and analyze several factors affecting the compliance in patients with gastric cancer. METHODS: From February 2012 to December 2014, we collected data of patients with gastric cancer who received adjuvant chemotherapy (TS-1 monotherapy or XELOX: capecitabine/oxaliplatin) in Korea. RESULTS: We collected data of 1,089 patients from 31 institutions. The completion rate and dose reduction rate by age (≥60 years vs. <60 years) were 57.5% vs. 76.8% (P < 0.001) and 17.9% vs. 21.3% (P = 0.354); by body mass index (BMI) (≥23 kg/m2 vs. <23 kg/m2) were 70.2% vs. 63.2% (P = 0.019) and 19.2% vs. 19.9% (P = 0.987), respectively. The compliance by American Society of Anesthesiologists physical status (ASA PS) classification was as follows: completion rate was 74.4%, 62.8%, and 60% (P = 0.001) and the dose reduction rate was 18.4%, 20.7%, and 17.8% (P = 0.946) in ASA PS classification I, II, and III, respectively. The completion rate of TS-1 and XELOX was 65.9% vs. 70.3% (P = 0.206) and the dose reduction rate was 15.7% vs. 33.6% (P < 0.001). Furthermore, the completion rate of chemotherapy by surgical oncologists and medical oncologists was 69.5% vs. 63.2% (P = 0.028) and the dose reduction rate was 17.4% vs. 22.3% (P = 0.035), respectively. CONCLUSION: The compliance was lower in patients who were older than 60 years, had BMI <23 kg/m2, and had higher ASA PS classification. Furthermore, the patients showed higher compliance when they received chemotherapy from surgical oncologists rather than from medical oncologists.
Body Mass Index ; Chemotherapy, Adjuvant ; Classification ; Compliance ; Drug Therapy ; Humans ; Korea ; Stomach Neoplasms

Purpose: To compare long-term disease-free survival (DFS) between patients receiving tegafur/gimeracil/oteracil (S-1) or capecitabine plus oxaliplatin (CAPOX) adjuvant chemotherapy (AC) for gastric cancer (GC). Materials and Methods: This retrospective multicenter observational study enrolled 983 patients who underwent curative gastrectomy with consecutive AC with S-1 or CAPOX for stage II or III GC at 27 hospitals in Korea between February 2012 and December 2013. We conducted propensity score matching to reduce selection bias. Long-term oncologic outcomes, including DFS rate over 5 years (over-5yr DFS), were analyzed postoperatively. Results: The median and longest follow-up period were 59.0 and 87.6 months, respectively. DFS rate did not differ between patients who received S-1 and CAPOX for pathologic stage II (P=0.677) and stage III (P=0.899) GC. Moreover, hazard ratio (HR) for recurrence did not differ significantly between S-1 and CAPOX (reference) in stage II (HR, 1.846; 95% confidence interval [CI], 0.693–4.919; P=0.220) and stage III (HR, 0.942; 95% CI, 0.664–1.337; P=0.738) GC. After adjustment for significance in multivariate analysis, pT (4 vs. 1) (HR, 11.667; 95% CI, 1.595–85.351; P=0.016), pN stage (0 vs. 3) (HR, 2.788; 95% CI, 1.502–5.174; P=0.001), and completion of planned chemotherapy (HR, 2.213; 95% CI, 1.618–3.028; P<0.001) were determined as independent prognostic factors for DFS. Conclusions S-1 and CAPOX AC regimens did not show significant difference in over-5yr DFS after curative gastrectomy in patients with stage II or III GC. The pT, pN stage, and completion of planned chemotherapy were prognostic factors for GC recurrence.