1.Retraction: Non-specific Immune Response of Rainbow Trout (Oncorhynchus Mykiss) by Dietary Heat-inactivated Potential Probiotics. Immune Network 2008;8(3):67-74..
Sang Hoon CHOI ; Taek Joon YOON
Immune Network 2011;11(5):307-307
I deeply regret but request a retraction of our paper published in Immune Network.
2.Retraction: Non-specific Immune Response of Rainbow Trout (Oncorhynchus Mykiss) by Dietary Heat-inactivated Potential Probiotics. Immune Network 2008;8(3):67-74..
Sang Hoon CHOI ; Taek Joon YOON
Immune Network 2011;11(5):307-307
I deeply regret but request a retraction of our paper published in Immune Network.
3.Detection of the Gonadotropin Releasing Hormone (GnRH) and Its Receptor in Cancer Cell HT-1197 and HT-1376, and Effect of GnRH on Cancer Cell Cycle.
Sang Hoon BAIK ; Myeong Ok KIM ; Jong Yoon BAHK
Korean Journal of Urology 2001;42(2):172-179
Gonadotropin releasing hormone (GnRH) is believed to be pivotal hormone in hypothalamo-pituitary gonadal axis and the hypothalamus is believed as the exclusive organ producing GnRH and pituitary is for GnRH re ceptor until recently. Some reported the exptra-hypothalamic GnRH or extra-pituitary GnRH receptors from decades ago. The aims of this study are to confirm the existence of the GnRH receptor in bladder epithelial cancer cell, HT-1197 and HT-1376, and evaluated the possible role of the GnRH on cell cycle. The GnRH and GnRH receptor were detected by immunohistochemical staining and the effect of GnRH on cell cycle change in both cell line were studied by fluorescence activated cell sorter (FACS). The control cells were cultured at media supplemented with normal serum, and experimental group were cultured at media supplemented with charcoal stripped serum (CSS) which excluding peptide hormones except exogenous GnRH with different concentration. The GnRHs and GnRH receptors were detected at both cell lines and the cell cycle analysis showed that there were little difference in proportion of cell cycle among examined 10,000 cells in both cell lines, neither control nor experimental groups. This study shows that the GnRHs and GnRH receptors exist in bladder cancer cells and GnRH did not influence on the cell cycle progression. With this study, we suppose that the bladder cancer cells produce the GnRH and GnRH receptors and the role of the GnRF produced from the bladder cancer cells might be the autocrine rather than endo-or paracrine factor.
Axis, Cervical Vertebra
;
Cell Cycle*
;
Cell Line
;
Charcoal
;
Fluorescence
;
Gonadotropin-Releasing Hormone*
;
Gonadotropins*
;
Gonads
;
Hypothalamus
;
Peptide Hormones
;
Receptors, LHRH
;
Urinary Bladder
;
Urinary Bladder Neoplasms
4.Prefabricated Muscle Flap for Difficult wound Around the Knee Joint.
Hoon Bum LEE ; Pil Dong CHO ; Sug Won KIM ; Sang Yoon KANG ; Yoon Kyu CHUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(5):917-922
The reconstruction of soft tissue defects with open fracture around the knee joint is limited by its unique location. Free tissue transfer is hindered by the selection of the recipient vessel and problems of microsurgery. The arc of rotation, defect size, and location must be taken into consideration in the use of regional muscle transfer such as gastrocnemius. According to Mathes et al, the flap survival can be enhanced by selective division of the dominant segmental pedicles, only a part of which can normally be transposed safely on its minor segmental pedicle. Neovascularization, vascular proliferation, and dilatation have also been produced by the delay procedure using silicone sheets. The authors have used the delay procedures with wrapping of the gracilis or sartorius muscle which enabled distally-based transposition of these muscles. The method showed satisfactory outcome in resurfacing the wound around the knee joint. The indictions for this procedure were defects of moderate size and those difficult to reach with conventional muscle flaps. The flap could reach the upper one-third of the lower leg. Other merits are relative simplicity and reliability without significant extension of hospital stay. The drawbacks are the two operative procedures necessary and the risk of infection due to silicone sheets.
Dilatation
;
Fractures, Open
;
Knee Joint*
;
Knee*
;
Leg
;
Length of Stay
;
Microsurgery
;
Muscles
;
Silicones
;
Surgical Procedures, Operative
;
Wounds and Injuries*
5.The Role of Absorbable Pins in the Treatment of Fractures
Moon Sang CHUNG ; Sang Hoon LEE ; Kang Sup YOON ; Jin Sup YEOM
The Journal of the Korean Orthopaedic Association 1990;25(3):753-763
Since 1954 when the first biodegradable polymer, polyglycolic acid(PGA), was synthesized, many different biodegradable and tissue-tolerant materials have been invested and studied for internal fixation devices. The use of biodegradable materials for the internal fixation of fractures would avoid the need for later removal of the implant. However, problems of a physical and chemical nature have delayed the development of biodegradable implants applicable to fracture management. The authors reviewed 17 cases in which the absorbable pins made of poly-p-dioxanone were used for internal fixation at Seoul National University Hospital between December, 1987 and September, 1989, and report on 11 patients who had at least 6 months follow-up(average 9.1 months). The results were graded as excellent(5 cases), good(4 cases), poor(0 case), and questionable(2 cases). In the 9 cases where the absorbable pins were used for internal fixation of the intraarticular fractures or defects, satisfactory(excellent or good) results were obtained. In the 2 cases where the absorbable pins were used for intramedullary nailing, the role of the pins was questionable. There were no complications such as wound sinus formation, secondary displacement of the fragemts and delayed union or nonunion.
Absorbable Implants
;
Fracture Fixation, Intramedullary
;
Humans
;
Internal Fixators
;
Intra-Articular Fractures
;
Polymers
;
Seoul
;
Wounds and Injuries
6.The Clinical Applicability of Power Spectral Analysis of Heart Rate Variability in the Initial Phase of Hemorrhagic Shock.
Sang Won CHUNG ; Yoo Sang YOON ; Yoo Sun KIM ; Seung Ho KIM ; Hahn Shick LEE ; Hoon Sang CHI
Journal of the Korean Society of Emergency Medicine 2000;11(1):44-53
No abstract available.
Heart Rate*
;
Heart*
;
Shock, Hemorrhagic*
7.Microvascular Free Tissue Transfers for Reconstruction of Irradiated Lesions in the Head and Neck.
Soo Wook CHAE ; Kyung Suck KOH ; Joo Bong KIM ; Sang Hoon PARK ; Sang Hoon HAN ; Taik Jong LEE ; Soon Yuhl NAM ; Sang Yoon KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(3):340-344
Radiation therapy is an effective cancer treatment modality as a primary treatment in early cancer and as an adjuvant treatment in advanced cancer, especially in head and neck lesions, but it also causes irreversible chronic damages to overlying normal tissues that may lead to wound complications. As well, at the microscopic level, radiation injury causes both stasis and occlusion of small vessels. Therefore, surgical reconstruction of previously-irradiated lesions in the head and neck poses a great problem. Fifth-six patients with head and neck lesions underwent 57 microsurgical reconstructions between 1990-1998. Thirteen patients were irradiated before surgery. The previous radiation dose was 30-75.6 Gy. The free tissue transfer was successful in 52 of the 57 microsurgical reconstructions(91.2%). The success rate was 92.3%(12/13) in previously-irradiated patients and 90.9%(40/44) in nonirradiated patients. Postoperative complications, such as flap loss, fistula, and infection, developed in 4 irradiated patients and 8 nonirradiated patients. Overall complication rate was 30.8%(4/13) in previously-irradiated patients and 18.2%(8/44) in nonirradiated patients. Although the failure rate of previously-irradiated patients was higher than that of nonirradiated patients, there was no statistically significant difference between them. Thus, free tissue transfers in patients with previously-irradiated head and neck lesions are suitable for one-stage reconstruction.
Fistula
;
Head*
;
Humans
;
Neck*
;
Postoperative Complications
;
Radiation Injuries
;
Wounds and Injuries
8.Exposure Incidence of Porous Orbital Implants.
Dong Su KIM ; Sang Hoon KIM ; Il Han YOON
Journal of the Korean Ophthalmological Society 2003;44(12):2711-2719
PURPOSE: We evaluated clinical results and incidence of exposures of orbital implants according to operative methods (enucleation or evisceration) and types of orbital implants. METHODS: We retrospectively reviewed the charts of 222 patients who underwent hydroxy apatite or Medpor(R) implantation after enucleation or evisceration and were followed up for more than 3 months from July, 1992 to November, 2001 at department of ophthalmology, Busan Paik hospital. RESULTS: In 222 eyes of 222 patients, who underwent hydroxyapatite and Medpor(R) implantaion, the exposure of implants occurred in 21 eyes (9.5%). In these cases, the exposure of implants occurred in 16 (12.8%) of 125 eyes with hydroxyapatite implantation and 5 (5.2%) of 97 eyes with Medpor(R) implantation. The exposure of implants occurred in 6 (7.1%) of 84 eyes after enucleation and in 15(10.8%) of 138 eyes after evisceration. The exposure of implants occurred in 12 (12.2%) of 98 eyes that used standard evisceration and in 3 (7.5%) of 40 eyes that used modified evisceration. CONCLUSIONS: The exposure of Medpor(R) implants was less than that of hydroxyapatite implants. But, it was influenced by types of orbital implants as well as operator and operative skill. There are few differences of exposure rate between the modified evisceration and enucleation.
Busan
;
Durapatite
;
Humans
;
Incidence*
;
Ophthalmology
;
Orbit*
;
Orbital Implants*
;
Retrospective Studies
9.New quantitative measuring technique for microleakage of the restored tooth through 3D reconstruction.
Journal of Korean Academy of Conservative Dentistry 2004;29(5):413-422
Established microleakage tests have their own disadvantages. In this study, 3D reconstruction method was tried to overcome these disadvantages. Four types of microleakage tests were used and relationships among them were estimated: penetrated dye volume; marginal adaptability; degree of dye penetration and relative penetrated length to cavity wall. Twenty-four Class V cavities were bulk filled with composite (Esthet X) following surface treatments: N group (no treatment); E group (etching only); T group (etching + Prime & Bond NT). 50% silver nitrate was used as a dye solution after thermocycling (5degrees C & 55degrees C, 1,000 times). Teeth were serially ground with a thickness of 0.2 mm. Volume of dye penetration was estimated from a three-dimensionally reconstructed image with a software (3D-DOCTOR). Percentage of margin without gap was estimated from SEM and degree of dye penetration and the relative length of dye penetration to overall cavity wall were also estimated. ANOVA and Scheffe test for dye volume, Kruskal-Wallis and Mann-Whitney test for marginal quality, Spearman's rho test for checking of relationships among methods were used. The results were as follows: 1. Dye penetration could be seen from several directions, furthermore, its volumetric estimation was possible. 2. Reverse relationship was found between dye volume and marginal quality (r = -0.881 / p = 0.004). 3. Very low relationship was seen between dye volume and two-dimensional tests (degree of dye penetration and relative length). However, 2D evaluation methods showed high relationship (p = 0.002-0.054) each other. 4. Three times vertical section could be recommended as a 2D test.
Silver Nitrate
;
Tooth*
10.An analysis of 26 consecutive cases of free flaps in head and neck.
Kyung Bo SIM ; Sang Hoon HAN ; Kyung Suk KOH ; Kun Chul YOON ; Bok Sung CHUNG
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1993;20(3):612-623
No abstract available.
Free Tissue Flaps*
;
Head*
;
Neck*