1.Utility of Lamellar Body Count in the Assessment of Fetal Lung Maturity.
Bong Gyu KWAK ; Sang Hoon LEE ; Moon Seok CHA ; Hyun Ho KIM
Korean Journal of Perinatology 2000;11(3):330-334
No abstract available.
Lung*
2.Transcatheter arterial embolization of Aneurysmal Bone Cyst in Pubic Bone: A Case Report
Jae Do KANG ; Kwang Yeul KIM ; Dong Gil KWAK ; Sang Hoon GO
The Journal of the Korean Orthopaedic Association 1994;29(1):300-305
Aneurysmal bone cyst uncommonly involves the pubic bone and tends to grow eccentrically and thin out overlying cortex. In the following case report, a 19-year-old male patient visited out hospital, because of dull pain in his left groin. He was diagnosed as aneurysmal bone cyst originated from the superior pubic ramus by CT guided needle biopsy. Transcatheter arterial embolization was effective in the treatment of this lesion such as complete consolidation after the procedure. At present, 2 years follow-up, no problem was noted at weight bearing as well as hip function or recurrence.
Aneurysm
;
Biopsy, Needle
;
Bone Cysts
;
Follow-Up Studies
;
Groin
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Hip
;
Humans
;
Male
;
Pubic Bone
;
Recurrence
;
Weight-Bearing
;
Young Adult
3.Normality Test in Clinical Research.
Sang Gyu KWAK ; Sung Hoon PARK
Journal of Rheumatic Diseases 2019;26(1):5-11
In data analysis, given that various statistical methods assume that the distribution of the population data is normal distribution, it is essential to check and test whether or not the data satisfy the normality requirement. Although the analytical methods vary depending on whether or not the normality is satisfied, inconsistent results might be obtained depending on the analysis method used. In many clinical research papers, the results are presented and interpreted without checking or testing normality. According to the central limit theorem, the distribution of the sample mean satisfies the normal distribution when the number of samples is above 30. However, in many clinical studies, due to cost and time restrictions during data collection, the number of samples is frequently lower than 30. In this case, a proper statistical analysis method is required to determine whether or not the normality is satisfied by performing a normality test. In this regard, this paper discusses the normality check, several methods of normality test, and several statistical analysis methods with or without normality checks.
Data Collection
;
Methods
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Normal Distribution
;
Statistics as Topic
4.A Case of Nanophthalmos.
Sang Wroul SONG ; No Hoon KWAK ; Warne HUH
Journal of the Korean Ophthalmological Society 1996;37(4):692-696
Nanophthalmos is a rare disease that results from arrested development of the globe after closure of the embryonic fissure and is characterized by a small eye with thickened sclera, uveal effusion, non-rhegmatogenous retinal detachment and narrow angle glaucoma. Treatments include medical, laser and surgical theraphy for glaucoma, and surgical treatments like scleral resection, anterior sclerotomy and vortex vein decompression surgery for the drainage of the uveal effusion, etc. We experienced a case of nanophthalmos with narrow angle glaucoma and choroidal effusion in 34 year-old male patients. Anterior sclerotomy for the drainage of the uveal effusion was performed and the scleral tissue obtained. Histopathologic study on the sclera showed abnormal collagen fibers.
Adult
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Choroid
;
Collagen
;
Decompression
;
Drainage
;
Glaucoma
;
Humans
;
Male
;
Rare Diseases
;
Retinal Detachment
;
Sclera
;
Veins
5.Importance of High-Frequency Vestibular Function in the Prognosis of Bilateral Vestibulopathy
Seong Hoon BAE ; Gi Sung NAM ; Sang Hyun KWAK ; Sung Huhn KIM
Clinical and Experimental Otorhinolaryngology 2021;14(2):192-199
Objectives:
. The aim of this study was to investigate whether preserved vestibular function in the high-frequency range influences the prognosis of patients with bilateral vestibulopathy (BVP) after vestibular rehabilitation.
Methods:
. Twenty-four patients followed up with vestibular rehabilitation were recruited. The enrolled patients were divided into two groups according to the preservation of the high-frequency vestibulo-ocular reflex (VOR) based on the video head impulse test (vHIT). The results of computerized dynamic posturography and the Dizziness Handicap Inventory (DHI) survey collected at baseline and at the 6-month follow-up after vestibular rehabilitation therapy were analyzed.
Results:
. Both groups showed significantly increased composite and DHI scores after follow-up with vestibular rehabilitation. The group with preserved high-frequency VOR showed a better composite score (p=0.064) and vestibular score (p= 0.008) than the group with lost high-frequency VOR at the 6-month follow up. The DHI score significantly decreased only in the group with lost high-frequency VOR (p=0.047). Among the three vestibular function tests (caloric test, rotary chair test, and vHIT) used to diagnose BVP, only vHIT showed a significant correlation (p=0.015) with a favorable prognosis (composite score ≥70).
Conclusion
. Better treatment outcomes are likely in patients with BVP with preserved vestibular function in response to high-frequency stimulation, as measured by the vHIT.
6.Importance of High-Frequency Vestibular Function in the Prognosis of Bilateral Vestibulopathy
Seong Hoon BAE ; Gi Sung NAM ; Sang Hyun KWAK ; Sung Huhn KIM
Clinical and Experimental Otorhinolaryngology 2021;14(2):192-199
Objectives:
. The aim of this study was to investigate whether preserved vestibular function in the high-frequency range influences the prognosis of patients with bilateral vestibulopathy (BVP) after vestibular rehabilitation.
Methods:
. Twenty-four patients followed up with vestibular rehabilitation were recruited. The enrolled patients were divided into two groups according to the preservation of the high-frequency vestibulo-ocular reflex (VOR) based on the video head impulse test (vHIT). The results of computerized dynamic posturography and the Dizziness Handicap Inventory (DHI) survey collected at baseline and at the 6-month follow-up after vestibular rehabilitation therapy were analyzed.
Results:
. Both groups showed significantly increased composite and DHI scores after follow-up with vestibular rehabilitation. The group with preserved high-frequency VOR showed a better composite score (p=0.064) and vestibular score (p= 0.008) than the group with lost high-frequency VOR at the 6-month follow up. The DHI score significantly decreased only in the group with lost high-frequency VOR (p=0.047). Among the three vestibular function tests (caloric test, rotary chair test, and vHIT) used to diagnose BVP, only vHIT showed a significant correlation (p=0.015) with a favorable prognosis (composite score ≥70).
Conclusion
. Better treatment outcomes are likely in patients with BVP with preserved vestibular function in response to high-frequency stimulation, as measured by the vHIT.
7.Update on Medical Management of Acute Peripheral Facial Palsy
Sang Hoon KIM ; Min Young KWAK
Journal of Audiology & Otology 2025;29(1):1-7
Acute facial nerve palsy, particularly Bell’s palsy, is a common neurological disorder with an annual incidence of 20-30 cases per 100,000 individuals. It is characterized by sudden or gradual facial muscle palsy and is caused by viral reactivation, inflammation, or ischemia of the facial nerve. Prognosis varies widely, depending on the severity of nerve damage and timeliness of the intervention. Steroid therapy remains the cornerstone of Bell’s palsy treatment because it reduces inflammation and facilitates recovery. Early administration, preferably within 72 hours of symptom onset, considerably improves outcomes. However, the efficacy of combination therapy remains controversial. Current guidelines recommend oral steroids as the primary treatment for Bell’s palsy and suggest the selective use of antiviral agents in severe cases or when viral involvement is strongly suspected. For severe facial palsy, such as Ramsay Hunt syndrome or varicella-zoster virus-induced cases, combination therapy may improve outcomes and reduce sequelae; however, high-quality evidence is limited. Steroid therapy is the main treatment of Bell’s palsy and antiviral therapy can be added in severe cases to improve prognosis. Additional research is required to develop standardized guidelines, concerning the use of antiviral therapies in conjunction with steroids.
8.Update on Medical Management of Acute Peripheral Facial Palsy
Sang Hoon KIM ; Min Young KWAK
Journal of Audiology & Otology 2025;29(1):1-7
Acute facial nerve palsy, particularly Bell’s palsy, is a common neurological disorder with an annual incidence of 20-30 cases per 100,000 individuals. It is characterized by sudden or gradual facial muscle palsy and is caused by viral reactivation, inflammation, or ischemia of the facial nerve. Prognosis varies widely, depending on the severity of nerve damage and timeliness of the intervention. Steroid therapy remains the cornerstone of Bell’s palsy treatment because it reduces inflammation and facilitates recovery. Early administration, preferably within 72 hours of symptom onset, considerably improves outcomes. However, the efficacy of combination therapy remains controversial. Current guidelines recommend oral steroids as the primary treatment for Bell’s palsy and suggest the selective use of antiviral agents in severe cases or when viral involvement is strongly suspected. For severe facial palsy, such as Ramsay Hunt syndrome or varicella-zoster virus-induced cases, combination therapy may improve outcomes and reduce sequelae; however, high-quality evidence is limited. Steroid therapy is the main treatment of Bell’s palsy and antiviral therapy can be added in severe cases to improve prognosis. Additional research is required to develop standardized guidelines, concerning the use of antiviral therapies in conjunction with steroids.
9.Update on Medical Management of Acute Peripheral Facial Palsy
Sang Hoon KIM ; Min Young KWAK
Journal of Audiology & Otology 2025;29(1):1-7
Acute facial nerve palsy, particularly Bell’s palsy, is a common neurological disorder with an annual incidence of 20-30 cases per 100,000 individuals. It is characterized by sudden or gradual facial muscle palsy and is caused by viral reactivation, inflammation, or ischemia of the facial nerve. Prognosis varies widely, depending on the severity of nerve damage and timeliness of the intervention. Steroid therapy remains the cornerstone of Bell’s palsy treatment because it reduces inflammation and facilitates recovery. Early administration, preferably within 72 hours of symptom onset, considerably improves outcomes. However, the efficacy of combination therapy remains controversial. Current guidelines recommend oral steroids as the primary treatment for Bell’s palsy and suggest the selective use of antiviral agents in severe cases or when viral involvement is strongly suspected. For severe facial palsy, such as Ramsay Hunt syndrome or varicella-zoster virus-induced cases, combination therapy may improve outcomes and reduce sequelae; however, high-quality evidence is limited. Steroid therapy is the main treatment of Bell’s palsy and antiviral therapy can be added in severe cases to improve prognosis. Additional research is required to develop standardized guidelines, concerning the use of antiviral therapies in conjunction with steroids.
10.Short-term Follow-up Results of Medial Epicondylar Osteotomy for the Varus Knee in TKA.
Jae Ang SIM ; Ji Hoon KWAK ; Sang Hoon YANG ; Joon Yub KIM ; Beom Koo LEE
Journal of the Korean Knee Society 2009;21(3):197-204
PURPOSE: We wanted to evaluate the results of medial epicondylar osteotomy for the varus knee when performing total knee arthroplasty. MATERIALS AND METHODS: We reviewed 32 cases of medial epicondylar osteotomy for treating varus deformity, and these cases underwent operation from December 2004 to December 2007. The average age of the patients was 71.0-years-old and the average follow-up period was 23.5 months. The clinical outcomes were measured, including the Knee Society score (KSS), the function score (FS) and the range of the motion (ROM). The radiological outcomes were measured by anteroposterior simple radiographs for assessing the union state of the osteotomy site, and the valgus stress radiographs and the whole extremity radiographs were used for assessing the femorotibial angle, the mechanical axis angle and the alignment. RESULTS: The KSS improved from 46.5+/-7.6 to 89.1+/-5.9 points (p<0.001) and the FS increased from 39.5+/-9.2 to 84.2+/-8.5 points (p<0.001). The range of motion increased from 101.5+/-28.2degrees to 116.0+/-10.8degrees (p=0.006). Bony union occurred in 22 knees and fibrous union occurred in 10 knees. The femorotibial angle was corrected from varus 8.2+/-5.0degrees to valgus 5.6+/-1.5degrees (p<0.001) and the mechanical axis angle was revised from varus 13.9+/-4.5degrees to varus 0.7+/-1.6degrees (p<0.001). There were 27 neutral, 4 varus and 1 valgus alignment. On the valgus stress radiographs, the difference compared with the opposite side was 1.0+/-0.6degrees and there was no significant difference between the bony union group and the fibrous union group (p=0.175). CONCLUSION: Medial epicondylar osteotomy for the varus knee when performing total knee arthroplasty could be a useful ligament balancing technique for achieving medial stability of the knee.
Arthroplasty
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Axis, Cervical Vertebra
;
Congenital Abnormalities
;
Extremities
;
Follow-Up Studies
;
Humans
;
Knee
;
Ligaments
;
Osteotomy
;
Range of Motion, Articular