Brodie's abscess is a primary subacute pyogenic osteomyelitis that has a thin wall of fibrous tissue and sclerotic bone. The authors have encountered a case of a Brodie's abscess that was developed in the same place of both tibia at the same time and treated the case with surgery and continuous closed irrigation.
Abscess ; Osteomyelitis ; Tibia

To investigate the effects of prostaglandin E1(PGX1) in prevention of proliferative scar formation, we cultured fibroblasts of normal skin (NS), hypertrophic scar (HS) and keloid (KL) tissues obtained from patients. We have compared type I collagenase production of cultured fibroblasts from normal skin, hypertrophic scar, and keloid tissues under various concentrations of PGE1. Our results demonstrate that type I collagenase production was significantly increased after addition of PGE1 in HS and KL, but not NS. Type I collagenase production of HS and KL fibroblasts were increased similarly in 10M and 10M of PGE1 and maximally increased in the concentration of 10M. This promotive effects of PGE1 on the production of type I collagenase was larger in KL than in HS. These results also suggest that PGE1 may play the promotive effects on type I collagenase production in dose-dependent manner. PGE1 may have a role in the prevention of hypertrophic scar and keloid by enhancing the production of type I collagenase of HS and KL fibroblasts. The promotive effects of PGE1 on type I collagenase production was variable depending on its concentration, and its effects was maximum in certain optimal condition. The maximally effective concentration of PGE1 in the prevention of proliferative scar formation should be searched in further investigations for clinical use.
Alprostadil ; Cicatrix ; Cicatrix, Hypertrophic* ; Collagenases* ; Fibroblasts* ; Humans ; Keloid* ; RNA, Messenger* ; Skin

No abstract available.
Apnea* ; Doxapram*

No abstract available.
Tonsillectomy*

No abstract available.
Lithotripsy* ; Salivary Gland Calculi* ; Salivary Glands* ; Shock*

No abstract available.

Aneurysmal bone cyst uncommonly involves the pubic bone and tends to grow eccentrically and thin out overlying cortex. In the following case report, a 19-year-old male patient visited out hospital, because of dull pain in his left groin. He was diagnosed as aneurysmal bone cyst originated from the superior pubic ramus by CT guided needle biopsy. Transcatheter arterial embolization was effective in the treatment of this lesion such as complete consolidation after the procedure. At present, 2 years follow-up, no problem was noted at weight bearing as well as hip function or recurrence.
Aneurysm ; Biopsy, Needle ; Bone Cysts ; Follow-Up Studies ; Groin ; Hip ; Humans ; Male ; Pubic Bone ; Recurrence ; Weight-Bearing ; Young Adult

External fixation is regarded as the treatment of choice for type 2 and 3 open tibial fractures. However, external fixation alone, especially of an unstable fracture, can be complicated by high incidence of malunion, delayed union, loss of reduction, refracture, and pin-tract infection. Some surgeons tried to treat such problems by secondary intramedullary nailing, but they came to different results. The purpose of the present study is to eveluate our experience with secondary intramedullary nailing after external fixation of 6 cases of type 3B open tibia fractures and 1 case of type 3B femur fracture. These cases were followed for more than 13 months and the following results were obtained. 1. The external fixation had been maintained for an average of 62 days. 2. The mean interval between removal of the external fixator and intramedullary nailing was 23 days. 3. Antibiotics was injected for 2 weeks after removal of external fixator. 4. Reamed intramedullary nailing with static interlocking were done in all 13 cases. 5. Deep infections developed in 2 cases, one case which had been pin-tract infection was around intramedullary nail and the other in fracture site. 6. All cases were healed ultimately and average union time after nailing was 9 months.
Anti-Bacterial Agents ; External Fixators ; Femur ; Fracture Fixation, Intramedullary ; Fractures, Bone ; Incidence ; Surgeons ; Tibia ; Tibial Fractures

Recently the use of hydrochloric acid as a toilet disinfectant has become more common, and the risk of its ingestion is though to be increasing. We experienced a case of 67 year-old man who accidentally ingested hydrochloric acid and as a result developed a postprandial epigastric fullness end pain 3 weeks thereafter, The patient underwent an UGI series, fiberoptic gastroscope and abdominal ultrasonography and was found to have a gastric midbody stricture. A total gastreetomy and Roux-en- Y esophagojejunostomy was performed. We report this case with brief review of the literature.
Aged ; Constriction, Pathologic ; Eating ; Gastritis* ; Gastroscopes ; Humans ; Hydrochloric Acid* ; Ultrasonography

PURPOSE: To assess the myotoxicity of local anesthetics and antibiotics which are considered as the main causes of diplopia and extraocular motility disturbance following cataract surgery. METHODS: A total of 48 rabbits were classified into 4 groups. The control group received an injection of 0.3 ml normal saline in the subconjunctival space above the superior rectus muscle. The first experimental group received an injection of the same amount of a local anesthetic (2% lidocaine) in the same manner as the control group. The second group received an injection of 0.3 ml of a local anesthetic directly into the extraocular muscle (superior rectus muscle), the third group received an injection of 0.3 ml of an antibiotic (gentamicin) in the subconjunctival space above the superior rectus muscle. Histologic and electron microscopic changes following injections were compared over time in each group. RESULTS: Light microscopic findings showed that subconjunctival injections of antibiotics caused the most severe inflammatory and fibrotic reactions of the muscular fascicle, whereas subconjunctival injections of local anesthetics led to the least damage of the muscular fascicle and less infiltration of inflammatory cells. Changes in histological findings showed that necrotic muscle fibers and inflammatory cell infiltration at 1 week following injections. Basophilic myogenous satellite cells indicating regeneration of the damaged muscles appeared thereafter. At 2 and 4 weeks, the group injected with antibiotic showed local and consistent infiltration of inflammatory cells and fibrosis, whereas the groups injected with anesthetics showed regeneration of most of the damaged fascicle. CONCLUSIONS: In terms of temporary or permanent diplopia following an injection of local anesthetics or antibiotics after cataract surgery, toxicity of anesthetics or antibiotics on extraocular muscle is the main cause from these Results.
Anesthetics ; Anesthetics, Local ; Anti-Bacterial Agents ; Basophils ; Cataract* ; Diplopia* ; Fibrosis ; Gentamicins ; Lidocaine ; Muscles ; Rabbits ; Regeneration