1.Influence of weight gain to cardiovascular risk factors.
Dong Ho KANG ; Noh Won PARK ; Jeong Yeol OH ; Won Keun LEE ; In Sang YOO
Journal of the Korean Academy of Family Medicine 1997;18(7):722-730
BACKGROUND: The obese patients increased recently in Korea due to excessive energy intake and decreased physical activity. We are well known that obesity is associted with an increased risk of cardiovascular disease, angina pectoris, hypertension, but not known to influence of weight gain to change in cardio-vascular risk factors. Once, the study of obesity are many but the study of influence of weight gain are small in Korea. This study investigated to influence of weight gain in cardio-vascular risk factors. METHODS: We gatherd case and control group among persons who has taken twice medical examination except disease person from October 1990 to October 1995 at SungAe General hospital. In our study, total 167 case, compare weight gain group(>3kg) with control group to change in cardiovascular risk factor. RESULTS: Sex, age, smoking history, obesity index were not statistically significant difference between two group in the first medical examination. systolic blood pressure, diastolic blood pressure, fasting blood sugar, HDL, total cholesterol/HDL were not statistically significant difference between two group for weight gain. Total cholesterol and triglyceride, LDL were stastistically significant increased. CONCLUSIONS: Weight gain was increased of total cholestrol and triglyceride, LDL, so weight control was important.
Angina Pectoris
;
Blood Glucose
;
Blood Pressure
;
Cardiovascular Diseases
;
Cholesterol
;
Energy Intake
;
Fasting
;
Hospitals, General
;
Humans
;
Hypertension
;
Korea
;
Motor Activity
;
Obesity
;
Risk Factors*
;
Smoke
;
Smoking
;
Triglycerides
;
Weight Gain*
3.IL-10 is Predominantly Produced by CD19(low)CD5(+) Regulatory B Cell Subpopulation: Characterisation of CD19 (high) and CD19(low) Subpopulations of CD5(+) B cells.
Jae Ho LEE ; Joonyong NOH ; Geunwoong NOH ; Wahn Soo CHOI ; Sang Sun LEE
Yonsei Medical Journal 2011;52(5):851-855
IL-10 production by CD19(+)CD5(+) B cells was investigated, by determining the expression levels of CD19, a classical B cell marker. Peripheral mononuclear cells were stained with fluorescence-conjugated anti-CD5, anti-CD19, anti-IL-10, and Annexin V. Interestingly, IL-10-producing B cells were found to be localised within the CD19(low)CD5(+) B cell subset. Apoptotic changes were also observed mainly in CD19(low) cells among B cells. Thus, CD5(+) B cells should be classified as CD19(high) and CD19(low) cells, and the immunological significance of CD19 for the IL-10 production by CD5(+) B cells requires further studies.
Antigens, CD19/metabolism
;
Antigens, CD5/metabolism
;
Apoptosis/immunology
;
B-Lymphocyte Subsets/cytology/*immunology
;
Cell Separation
;
Flow Cytometry
;
Humans
;
Interleukin-10/*biosynthesis
4.Normal Glenoid Size of the Korean in 7th and 8th Decades.
Young Lae MOON ; Sang Ho HA ; Kyung Hwan NOH
Journal of the Korean Shoulder and Elbow Society 2008;11(1):37-40
PURPOSE: We wanted to evaluate the normal glenoid size of Koreans in their 7th and 8th decades by conducting Computed tomographic (CT) studies. MATERIALS AND METHODS: The CT images were obtained from the normal scapulae of the patients (mean age: 68.8) who had humeral fracture. A display workstation version 2.0.73.315 was used to measure the scans to determine the maximal superoinferior (SI) and anteroposterior (AP) diameters of the glenoid vault. RESULTS: The average diameters of curvature of the glenoid were 31.2 mm (range: 27 to 34 mm) in the superior-inferior direction and 26.1mm (range: 22 to 31mm) in the anterior-posterior direction. CONCLUSION: This study showed the normal glenoid size of Koreans and it is different from the size that the international literature reported. It should be an important factor for the treatment of fracture or in designing arthroplasty implants.
Arthroplasty
;
Humans
;
Humeral Fractures
;
Scapula
;
Shoulder
5.Sudden Death from Acute Epiglottitis and Epiglottic Abscess in Adult.
Korean Journal of Legal Medicine 2015;39(2):49-52
Acute epiglottitis is an inflammation of the epiglottis and adjacent structures. Although the incidence is extremely rare, acute epiglottitis is a life-threatening medical emergency and can cause sudden respiratory obstruction. Herein, we describe two cases of sudden death from epiglottitis and epiglottic abscess. A 39-year-old man and 66-year-old man died after suffering from shortness of breath. Autopsies revealed diffuse swelling and abscess formation in the epiglottis and neighboring structures. These cases emphasize the medicolegal importance of sudden death from acute epiglottitis and epiglottic abscess in adults.
Abscess*
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Adult*
;
Aged
;
Airway Obstruction
;
Autopsy
;
Death, Sudden*
;
Dyspnea
;
Emergencies
;
Epiglottis
;
Epiglottitis*
;
Humans
;
Incidence
;
Inflammation
6.Bilateral Juvenile Retinoschisis in four Brothers of a Family.
Byung Bae NOH ; Sang Joon LEE ; Ho Kyung LEE
Journal of the Korean Ophthalmological Society 1993;34(10):1060-1067
Juvenile retinoschisis is a vitreoretinal dystrophy with X-linked recessive mode of transmission that shows microcystic degeneration of the macula associated with splitting of the sensory retina, predominantly within the nerve fiber layer. We experienced X-linked juvenile retinoschisis, in four borthers within a family in which were the onset of visual disturbance between second decades and third decades, and all showed maculopathy, RPE atrophy, vitreous veils extended to vitreous, partial optic atrophy, specific electroretinographic findings.
Atrophy
;
Humans
;
Nerve Fibers
;
Optic Atrophy
;
Retina
;
Retinoschisis*
;
Siblings*
7.Sudden Cardiac Death from Acute Myocardial Infarction Caused by Unruptured Ascending Aortic Aneurysm Involving the Sinus of Valsalva: An Autopsy Case
Yu Ra JANG ; Ho LEE ; Sang Jae NOH
Korean Journal of Legal Medicine 2023;47(4):171-173
Ascending aortic aneurysm of the thorax is a condition characterized by an increase in the diameter of the ascending aorta between the aortic valve and the brachiocephalic artery. Most patients with ascending aortic aneurysm are asymptomatic and do not require treatment; the rates of dissection, rupture, and mortality are also low. In this report, we describe the autopsy findings in a case of sudden death due to acute myocardial infarction secondary to the previously asymptomatic, unruptured, and undissected aortic aneurysm of the thoracic ascending aorta extending to the sinus of Valsalva. The findings in this case emphasize the importance of preventive management of asymptomatic ascending aortic aneurysms, and possible mechanisms of sudden cardiac death in patients with uncomplicated ascending aortic aneurysm is also discussed.
8.Three Cases of Vitiligo Showing Response to Application of Latanoprost.
Seongmin NOH ; Tae Gyun KIM ; Sang Ho OH
Korean Journal of Dermatology 2010;48(4):350-353
Vitiligo, which is characterized by depigmentation of skin and mucosa is a common skin disease, affecting 1-4% of population. Although the pathogenesis is not clear, the basic defect lies in a decrease or absence of melanocytes. Vitiligo causes cosmetic disfiguration and exerts negative effects on quality of life. Phototherapy and topical agents such as corticosteroids, calcineurin inhibitors, and vitamin-D derivatives are basic treatment modalities. Recently, prostaglandin analogues have been reported to be effective on pigmentation of vitiligo lesions. We present three patients with periorbital vitiligo, who did not respond to established treatments such as tacrolimus and excimer laser, responding to application of latanoprost, a prostaglandin F2alpha analogue.
9.Traumatic ossicular disruption.
Sun O CHANG ; Chong Sun KIM ; Phil Sang CHUNG ; Hong Ryul JIN ; Keun Ho CHANG ; Kwan Taek NOH
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):861-868
No abstract available.
10.A cephalometric study on correlation between mandibular symphysis and craniofacial skeleton.
Sang Ho NOH ; Ki Soo LEE ; Yong Kuk PARK
Korean Journal of Orthodontics 1997;27(1):119-127
The configuration of mandibular symphysis is likely to be dependent upon the genetic predeterminants and/or compensatory adjustments onto functional demands. The interrelation of morphological distinctives of symphysis in conjunction to the craniofacial skeleton had been scarcely anecdotal, therefore, the objective was to determine the correlation of morphological modifications between the mandibular symphysis and craniofacial complex. Lateral cephalometric headfilms of 212 subjects were employed for the conventional measurements. The proportion of chin height against chin depth length was referred as chin ratio, then, Low Symphysis (IS) and High Symphysis (HS) groups were turned out by means of the chin ratio. These samples yielded 35 in LS and 35 in HS groups. The data per capita were statistically analyzed and the following results were drawn ; 1. Overall characteristics of the craniofacial skeleton in HS group manifested hyperdivergence and LS group showed hypodivergence. 2. Gonial angle increased as chin ratio increased and was highly correlated to the chin ratio. 3. The chin ratio presented high correlation to the vertical face height, especially in terms of the chin height to anterior face height and the chin depth to posterior face height. 4. The morphological configuration of chin was hardly correlated with hyoid bone position.
Chin
;
Hyoid Bone
;
Skeleton*