No abstract available.
Animals ; Hindlimb Suspension* ; Hindlimb*

No abstract available.

No abstract available.
Animals ; Gene Expression* ; Hypothalamus* ; Immunohistochemistry* ; In Situ Hybridization* ; Rats* ; Vasopressins*

A subperiosteal ganglion has been very rarely reported, since Ollier reported first one in 1864. A subperiosteal ganglion is produced by mucoid degeneration and cyst formation within the periosteum, which results in cortical erosion. The characteristic plain radiolographic appearance of irregular cortical erosion and scalloping, with reactive periosteal bone spicules, has been considered pathognomonic of subperiosteal ganglion. Magnetic resonance imaging is performed to further characterize the soft tissue component of the mass. As in our patient, the characteristic signal intensities of magnetic resonance imaging are especially useful in identifying the lesion as a ganglion and in defining the lobular nature and the anatomical extent. We report here the case of a 35-year-old female who had a sudperiosteal ganglion of the distal radius.
Adult ; Female ; Ganglion Cysts* ; Humans ; Magnetic Resonance Imaging ; Pectinidae ; Periosteum ; Radius*

BACKGROUND: With increasing number of female pilots who fly high-performance aircraft, the gender specific factors have become one of the most important aeromedical considerations. It has been raised that the changes of serum female hormone levels by menstrual cycle may affect vasoregulation and female G-tolerance ultimately. However, the exact relationship between serum female hormone levels and G-tolerance is still unknown. Moreover, well-controlled subjects without taking oral contraceptives are needed to examine the possible effect of menstrual cycle on female G-tolerance. The purpose of this study was to determine how female hormones and menstrual cycle affect female relaxed G-tolerance. METHODS: Eight female subjects were studied to test their relaxed G-tolerance. Seven out of 8 subjects had regular menstrual cycle during the study period. Each subject were exposed to human centrifuge once a week for 4 weeks (one complete menstrual cycle) and blood samplings were performed twice at 2nd and 4th week just before exposure to human centrifuge. The profile of centrifuge training consisted of gradual-onset run (0.1 G/sec) acceleration to the visual endpoint. RESULTS: The changes of 4 different serum female hormone levels failed to show any trend related to relaxed G-tolerance including estrogen. There was no significant difference in relaxed G-tolerance in any menstrual cycle time points. CONCLUSION: We conclude that the changes of female hormone levels and the menstrual cycle have no effect on female relaxed G-tolerance.
Acceleration ; Aircraft ; Contraceptives, Oral ; Diptera ; Estrogens ; Female* ; Humans ; Menstrual Cycle*

A 4-year-old boy has had a solitary sclerotic depressed plaque on the right anterior chest since birth. The histopathologic findings are consistent with morphea profunda: thickening, hyalinization, and homogenization of collagen bundles in the dermis and subcutaneous tissues, admixture with a prominent lymphocytic and plasma cell infiltrate, and sweat glands en-trapped between the thickened collagen bundles. We report a case of congenital solitary morphea profunda.
Child, Preschool ; Collagen ; Dermis ; Humans ; Hyalin ; Male ; Parturition ; Plasma Cells ; Scleroderma, Localized* ; Subcutaneous Tissue ; Sweat Glands ; Thorax

Cytomegalovirus(CMV) retinitis is the most common opportunistic retinal in fection seen in patients with AIDS. It is almost always progressive and, if untreated, often leads to blindness. The authors report a case of unilateral CMV retinitis in 29-year-old female with AIDS, who complained of decreased vision in the left eye. Fundus examination showed areas of dense white retinal necrosis, scattered hemorrhages and perivascular sheathings. On urine culture CMV was also isolated. Treatment with ganciclovir was started and during the 2 mon ths of treatment, the retinitis was markedly resolved and visual acuity was improved to 0.7. CMV retinitis did not develop in the right eye.
Adult ; Blindness ; Cytomegalovirus Retinitis* ; Cytomegalovirus* ; Female ; Ganciclovir* ; Hemorrhage ; Humans ; Necrosis ; Retinaldehyde ; Retinitis ; Visual Acuity

Diode laser photocoagulation with laser ophthalmoscope has been shown to be effective and safe for treatment of threshold ROP. The purpose of this study are to deternine whether diode laser photocoagulation is really effective in reducing the likelihood of unfavorable regults in threshold stage. The eyes of neonates with birthweight of 2,500g or less, gestational age of 37 weeks or less, or exposure to increased ambient oxygen between May 1994 and October 1995 were examined, 21 eyes of threshold level of ROP and 2 eyes of prethreshold stage received diode laser photocoagulation. Nineteen(83%) of the 23 eyes that underwent laser photocoagulation had a favorable respons. Retinopathy of prematurity, however progressed to stage 4 in 2 eyes and stage 5 in 2 eyes. Two eyes in stage 4 achieved retinal reattachment after retinal buckling operation, but two eyes in stage 5 did not achieved retina1 reattachment. Regarding complications, one eye had retinal hemorihagic spot and one had presumed Bruch's membrane rupture. All infants had been followed up for minimum of 6 months. The results suggest that diode laser photocoagulation is an effective method in treatment of ROP, technically easier to administer without significant complication.
Bruch Membrane ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Lasers, Semiconductor* ; Light Coagulation* ; Ophthalmoscopes ; Oxygen ; Retinaldehyde ; Retinopathy of Prematurity* ; Rupture

Diode laser photocoagulation with laser ophthalmoscope has been shown to be effective and safe for treatment of threshold ROP. The purpose of this study are to deternine whether diode laser photocoagulation is really effective in reducing the likelihood of unfavorable regults in threshold stage. The eyes of neonates with birthweight of 2,500g or less, gestational age of 37 weeks or less, or exposure to increased ambient oxygen between May 1994 and October 1995 were examined, 21 eyes of threshold level of ROP and 2 eyes of prethreshold stage received diode laser photocoagulation. Nineteen(83%) of the 23 eyes that underwent laser photocoagulation had a favorable respons. Retinopathy of prematurity, however progressed to stage 4 in 2 eyes and stage 5 in 2 eyes. Two eyes in stage 4 achieved retinal reattachment after retinal buckling operation, but two eyes in stage 5 did not achieved retina1 reattachment. Regarding complications, one eye had retinal hemorihagic spot and one had presumed Bruch's membrane rupture. All infants had been followed up for minimum of 6 months. The results suggest that diode laser photocoagulation is an effective method in treatment of ROP, technically easier to administer without significant complication.
Bruch Membrane ; Gestational Age ; Humans ; Infant ; Infant, Newborn ; Lasers, Semiconductor* ; Light Coagulation* ; Ophthalmoscopes ; Oxygen ; Retinaldehyde ; Retinopathy of Prematurity* ; Rupture

BACKGROUND: In a condition of microgravity, arteries of upper body part are exposed to relative hypertensive stress, which is induced by headward fluid shift. We already have reported the increase of monocyte adhesion and intercellular adhesion molecule-I (ICAM-I) expression in carotid artery and thoracic aorta in the simulated microgravity. The purpose of this study was to identify the evidence of hypertensive arterial change in hindlimb unloading rats. METHODS: A total of 16 Sprague-Dawley rats were divided into the 2 and the 4 weeks hindlimb unloading groups and their control groups, respectively. After experimental exposure, the carotid artery, the thoracic/abdominal aorta, and the femoral artery were obtained from each experimental and control groups. The degree of matrix metalloproteinase (MMP)-2, MMP-9, and tissue inhibitor of MMPs type 1 (TIMP-1) expression were analyzed by immunohistochemical stain. RESULTS: The increase of MMP-2, 9 expression was noted in the carotid artery and the thoracic aorta from the 4 weeks hindlimb unloading group. On the other hand, the MMP-2, 9 expression was negligible in the abdominal aorta and the femoral artery of this group. In general, the findings of the 2 weeks hindlimb unloading group were similar to those of the control group. The TIMP expression was not found in all groups. CONCLUSION: We found the evidence of hypertensive arterial change by increased shear stress on upper body part's arteries in simulated microgravity. Considering the possible development of this change into hypertensive arterial damage with other cardiovascular risk factors, our findings can be highlighted as an important medical concern, especially in a long-term spaceflight.
Animals ; Aorta ; Aorta, Abdominal ; Aorta, Thoracic ; Arteries ; Carotid Arteries ; Femoral Artery ; Hand ; Hindlimb Suspension* ; Hindlimb* ; Matrix Metalloproteinases ; Monocytes ; Rats* ; Rats, Sprague-Dawley ; Risk Factors ; Space Flight ; Weightlessness