No abstract available.
Candida albicans* ; Candida* ; Dentures* ; Detergents*

The ultraviolet radiation (UVR) is known to be a potent modulator of many host immune functions and the exposure of experimental animals to the inflammatory effects of UVR induces depressions in their ability to initiate and effectuate various types of cellular immune responses. In this study, the effects of UV-B (280 320 nm) radiation on resistance to a facultative intracellular bacterium, Listeria monocytogenes (LM), were examined at the cellular level. The numbers of cultivable LM recovered from the spleens of UV-B-irradiated mice were decreased at 2 days postinfection compared with those of untreated control mice. However, the acquired immunity, developed 7 days after immunization with streptomycin (SM)-sensitive LM, in either UV-irradiated, LPS- or IL-1-pretreated mice was less stronger than that developed in untreated, control mice. To elucidate the possible mechanisms underlying the observation that UVR did increase innate immunity but decreased acquired immunity of mice to the infection with LM, the effects of UVR of mice on the production of IFN-r by activated splenocytes and TNF-a by peritoneal macrophages were assessed. Activated splenocytes from UV-irradiated mice exhibited a reduced capacity to produce IFN-r and cultured peritoneal macrophages produced more TNF-a in the presence of LPS during 24 hours after UV radiation. Though TNF-r activity was not detected in the sera of LM-infected mice, intravenous LPS injection induced TNF-r production and UVR decreased TNF activity in sera obtained from LM-infected mice with LPS induction 9 days after irradiation. Although Ia-negative macrophages were predominant in the peritoneal macrophages from untreated control mice, the infection of mice with LM caused a marked increase in Ia expression on peritoneal macrophages. However, UVR resulted in decreased expression of Ia molecule on the peritoneal macrophages during the LM infection. These findings suggest that the dual effects of UVR on the innate and acquired immunity of mice to the LM infection may be associated with altered capacities of splenocytes and peritoneal macrophages of the mice to produce cytokines, in addition to decrease of la molecule expression on the macrophages.
Adaptive Immunity ; Animals ; Cytokines ; Depression ; Immunity, Cellular ; Immunity, Innate ; Immunization ; Listeria monocytogenes* ; Listeria* ; Macrophages ; Macrophages, Peritoneal ; Mice* ; Spleen ; Streptomycin ; Tumor Necrosis Factor-alpha*

No abstract available.
Durapatite* ; Radionuclide Imaging*

The measurement of the intraocular pressure were made with the Mackay-Marg electronic applanation tonometer, as compared with standard Goldmann tonometer and Schiotz tonometer in Korean 114 normal eyes. The results were as follows: 1. The mean intraocular pressure of 114 normal eyes was 16.61 +/- 3. 77 mmHg with a Mackay-Marg tonometer. 2. There was significant differances between the Mackay-Marg tonometer and Goldmann tonometric values(p<0.005). The corelation coefficent(r) was 0.975, the linear regression was Y = 1.37 + 1.06X. 3. The standard deviation for Mackay-Marg tonometer was greater thandoldmann readings, and it was about 1.37 mmHg higher than Goldmann's. 4. There was significant differances between the Mackay-Marg tonometer and Schiotz tonometric values(p<0.005). The corelation coefficent(r) was 0.938, the linear regression was Y = 0.82X - 0.07.
Intraocular Pressure* ; Linear Models ; Reading

PURPOSE: This study was to identify the effect of hand massage on comfort in women with gynecologic cancer undergoing chemotherapy. METHODS: A nonequivalent control group pretest-posttest design was used for this study. Hand massage was provided to the experimental group for 5 min (2.5 min for each side) once on admission day, twice from the second day until the day before discharge, and once in the morning on discharge day. RESULTS: Findings showed no significant differences in pre and post levels of general, physical, psycho-spiritual, social and environmental comfort. However, women's comfort levels in all domains were increased after the chemotherapy in the experimental group. CONCLUSION: Although there were some increases in women's comfort levels on all domains after the treatment, hand massage was not proved as a statistically useful nursing intervention in comforting women with gynecologic cancer. The results suggest that hand massage could be effective if it is applied longer than it was in this study. The future implications of hand massage in patients with various cancers are discussed.
Female ; Hand ; Humans ; Massage

Midtrimester genetic amniocentesis has been a gold standard for prenatal diagnosis in antenatal care since last 25 years. After the triple serum marker test was introduced as a prenatal screening method for Down syndrome, the frequency of genetic amniocentesis was increased. OBJECTIVE: To determine the complication, risk of amniocentesis and detection rate of chromosomal abnormality. MATERIAL AND METHODS: A retrospective clinical analysis of 1,064 midtrimester genetic amnicentesis in IL Sin Christian Hospital antenatal clinic from Jan 1995 to Dec 1997. Chi square test was used for the statistical analysis and p value < 0.05 was considered significant. RESULTS: Amnicentesis were significantly increased in the age of 35-39 yrs and 40yrs over. And also the incidence of chromosomal abnormality was higher than younger age group. The indications of amnicentesis were screen positive of triple marker test(43%), advanced maternal age(20.8%), abnormal beta-hCG level, past history of chromosome abnormality or malformed baby and abnormal alpha-FP level in order. Total number of chromosomal abnormalities was 30 and the incidence of chromosomal abnormalities was 2.8%(30/1,064). The complications were developed in 13 cases and fetal loss rate was 0.78%(9/1,064). CONCLUSION: The detection rate of chromosomal abnormality in midtrimester amnicentesis for prenatal diagnosis was high and relatively safe procedure but, we should be attention to more careful manipulation.
Amniocentesis ; Biomarkers ; Chromosome Aberrations ; Down Syndrome ; Female ; Humans ; Incidence ; Pregnancy ; Pregnancy Trimester, Second* ; Prenatal Diagnosis ; Retrospective Studies

PURPOSE: This study aimed to assess the prevalence of asthma, allergic rhinitis, and atopic dermatitis in elementary school students according to thebody mass index. METHODS: This study was conducted as cross-sectional descriptive research using a structured questionnaire. Data were collected from 6,398 students at 15 elementary schools located in Y City in Korea. The cross-sectional survey used the Korean version of International Study of Asthma and Allergies in Childhood questionnaire. Logistic regression analysis was performed to estimate the odds ratios of body mass index. RESULTS: The symptom prevalence of asthma, allergic rhinitis, and atopic dermatitis in the last 12 months was 12.4%, 49.5%, and 24.5%, respectively. The symptom prevalence of asthma was significantly higher in the obesity group. The number of those without any asthma symptom in lifetime was significantly smaller in the overweight (OR=0.70, p=.004) and obesity (OR=0.57, p=.005) groups than in the healthy weight group. CONCLUSION: These results suggest that asthma, allergic rhinitis, and atopic dermatitis prevention programs for elementary school students should include weight control intervention.
Asthma* ; Body Mass Index* ; Cross-Sectional Studies ; Dermatitis ; Dermatitis, Atopic* ; Humans ; Hypersensitivity ; Korea ; Logistic Models ; Obesity ; Odds Ratio ; Overweight ; Prevalence* ; Rhinitis*

OBJECTIVES: This study aimed to identify the individual and regional characteristics that influence suicidal ideation among the Korean elderly population. METHODS: Using data collected from the 2013 Korea Community Health Survey, a multilevel analysis was performed to establish an understanding of individual behavioral patterns and regional influences on suicidal ideation. RESULTS: Among the 77,407 individuals sampled, 11,236 (14.5%) elderly people over 60 years of age experienced suicidal ideation. Among individual factors, age, frequency of communication with friends, religious activity, social activity, leisure activity, trust in neighbors, subjective stress level, depressive symptoms, and subjective health status were significantly associated with suicidal ideation. The results showed that the lower the regional deprivation level, the higher the suicidal ideation odds ratio. In terms of regional size, the most significant effects were found in rural areas. CONCLUSIONS: This study suggested that suicidal ideation in the elderly is associated with community factors, such as the regional deprivation index, as well as personal factors.
Age Factors ; Aged ; Depression ; Diagnostic Self Evaluation ; Friends ; Health Surveys ; Humans ; Korea ; Leisure Activities ; Multilevel Analysis ; Odds Ratio ; Socioeconomic Factors ; Suicidal Ideation

OBJECTIVES: This study aimed to identify the individual and regional characteristics that influence suicidal ideation among the Korean elderly population.METHODS: Using data collected from the 2013 Korea Community Health Survey, a multilevel analysis was performed to establish an understanding of individual behavioral patterns and regional influences on suicidal ideation.RESULTS: Among the 77,407 individuals sampled, 11,236 (14.5%) elderly people over 60 years of age experienced suicidal ideation. Among individual factors, age, frequency of communication with friends, religious activity, social activity, leisure activity, trust in neighbors, subjective stress level, depressive symptoms, and subjective health status were significantly associated with suicidal ideation. The results showed that the lower the regional deprivation level, the higher the suicidal ideation odds ratio. In terms of regional size, the most significant effects were found in rural areas.CONCLUSIONS: This study suggested that suicidal ideation in the elderly is associated with community factors, such as the regional deprivation index, as well as personal factors.
Age Factors ; Aged ; Depression ; Diagnostic Self Evaluation ; Friends ; Health Surveys ; Humans ; Korea ; Leisure Activities ; Multilevel Analysis ; Odds Ratio ; Socioeconomic Factors ; Suicidal Ideation

No abstract available in English.
Arthroscopy ; Knee Joint ; Knee