1.The clinical evaluation for children with orthostatic proteinuria.
Chan Sung LEE ; Chong Guk LEE ; Sang Woo KIM
Journal of the Korean Pediatric Society 1989;32(11):1520-1525
No abstract available.
Child*
;
Humans
;
Proteinuria*
2.Detection of Human Papillomavirus DNA 16/18 in Cervical Adenocarcinomas by Polymerase Chain Reaction.
Sang Sook LEE ; Nam Jo PARK ; Chong Guk YOON
Korean Journal of Pathology 1995;29(4):502-510
Twenty-five paraffin-embedded tumor tissues were analyzed for detection of HPV 16 and 18 in cervical adenocarcinoma by polymerase chain reaction with type specific primers and by non-radioactive Southern blot hybridization for confirmation . The suitability of paraffin-embedded tissue as PCR material was confirmed by successful amplification of 100% of cervical specimens with human -globin specific primer. Eighty four percent of the cervical adenocarcinoma tissues were positive for HPV 16 and/or 18. HPV 16 positive rate was 68%, HPV 18 was 60%. The double infection with HPV 16 and 18 was found in 44%. Three cases of the negative specimen in PCR for each type of HPV DNA 16 and 18 were positive in Southern blot hybridization. The total positive rate was 92% for HPV 16 and/or HPV 18, HPV 16 positive rate was 80%. HPV 18 was 72%. The double infection with HPV 16 and 18 was 60%. These results suggest that the pattern of HPV types 16 and 18 is closely associated with carcinogenesis of cervical cancers. HPV type 18 appears to be preferentially related to cervical adenocarcinoma and the poor prognosis of these patients. Therefore, determination of HPV DNA type in cervical carcinoma patients is important in treatment and prognosis.
Humans
;
Adenocarcinoma
3.A Case of Renal Tuberculosis in a Child.
Min Young CHA ; Se Yun EUN ; Chong Guk LEE ; Sang Il LEE ; Sang Woo KIM
Journal of the Korean Pediatric Society 1984;27(7):733-737
No abstract available.
Child*
;
Humans
;
Tuberculosis, Renal*
4.A Case of Hemolytic Uremic Syndrome.
Seung Cheol LEE ; Chong Guk LEE ; Seong Hwan KIM ; Sang Woo KIM ; Hyun Soon LEE
Journal of the Korean Pediatric Society 1990;33(8):1138-1145
No abstract available.
Hemolytic-Uremic Syndrome*
5.Factors Affecting Measurement Error of Vertebral Axial Rotation and Reduction of Measurement Error through Training.
Chong Suh LEE ; Sung Soo CHUNG ; Saeng GUK ; Dong Kook CHANG ; Sang Eun KIM
The Journal of the Korean Orthopaedic Association 1999;34(1):89-94
PURPOSE: To identify the changes of bony landmarks with rotation and to compare the reliability and accuracy of Perdriolle's method before and after training on the exact bony landmarks. MATERIALS AND METHODS: Simple A-P radiographs were taken with rotation from 5 degree to 50 degree at 5 degree interval using 10 dry human vertebrae (2 sets of T3, T6, T9 8 L3) with no bony abnormality. Axial rotation was measured before and after training on the exact bony landmarks by three observers, twice for each radiographs. Repeated measures of ANOVA were used for inter- < intraobserver variance and regression analysis for root mean square error and deviation of differences. RESULTS: Mamillary process, inner margin of lamina, proximal and distal costovertebral joints, upper margin of concave pedicle and tip of the transverse process on the convex side confused the exact outline of the pedicle, while neural foraminal margin was helpful in identifying the location of the indistinct convex pedicle and concave vertebral border. Of the 660 measurements before and after training 372 and 397 errors were made, respectively, of which 88.9% and 88.5% were within +/-5 degree(P > 0.05). Incidence of error greater than 5 degree was high at upper thoracic vertebra and 20 degree-40 degree of rotation regardless of training. The effects of training, however, was greatest at T3 and 20 degree-40 degree of rotation. Inter- < intraobserver variance was diminished at T3 and at the rotation between 20 degree-40 degree after training. CONCLUSIONS: We could conclude that training on the exact bony landmarks did not reduce the overall error incidence. Accuracy and reliability, however, was increased at T3 after training and the efficacy of training was more evident in moderate vertebral rotation than in small or large vertebral rotation.
Humans
;
Incidence
;
Joints
;
Spine
6.The Use of Flexible Intramedullary Nails in Fracture of the Tibial Shaft
Jang Sung LEE ; Kyo Woong KIM ; Byung Guk KIM ; Seung Ki JEONG ; Sang Young KIM
The Journal of the Korean Orthopaedic Association 1990;25(1):70-77
Forty five cases of adult tibial shaft fractures were treated with flexible intramedullary nails under image intensifier at the department of orthopaedic surgery, Capital Armed Forces General Hospital during between April 1986 to July 1988. The results were summarized as follows: 1. 45 cases were all male, the average age was 24.3 years and the most common cause of fractures was sports injury(20 cases) and the second most common cause was traffic accident(18 cases). 2. 11 cases out of 45 cases were open fracture and 34 cases were closed fracture. Eight cases of open fraeture were grade I and three cases were grade II. Twenty eight cases were comminuted fracture. The most common level of the fracture was middle third of the tibial shaft. 3. Average interval from injury to Ender nailing was 13.5 days and the mean duration of permission to full weight bearing was 9.2 weeks. 4. Out of 2 cases of delayed union, the average time of clinical bone union was 9.7 weeks and that of roentgenological bone union was 14 weeks. 5. 11 cases of complication were noted among the 45 cases of tibial shaft fracture which were treated by PGP nailing such as angulation, rotation, ankle joint stiffness, delayed union, shortening, and soft tissue infection. 6. PGP nailing is considered to be a valuable method in treating tibial shaft fracture because of their relative ease of nailing, allowing early weight bearing and decreased complication.
Adult
;
Ankle Joint
;
Arm
;
Fractures, Closed
;
Fractures, Comminuted
;
Fractures, Open
;
Hospitals, General
;
Humans
;
Male
;
Methods
;
Soft Tissue Infections
;
Sports
;
Tibial Fractures
;
Weight-Bearing
7.Ketogenic Diet Trial for The Treatment of Minor Motor Seizures.
Sang Pok SUCK ; Jong Guk LEE ; Sang Hyeup KEM ; Hahn Woong CHOE
Journal of the Korean Pediatric Society 1978;21(8):579-586
A 3-years-old girl, diagnosed as infantile spasm and 5-years-old boy, diagnosed as akinetic seizure were subjected to ketogenic diet trial because of their poor responses anticonyulsant treatment After adding ketogenic diet trial, in the former infantile spasm case, her seizures were controlled satisfactorily and in the latter akinetic seizure case, the frequency of seizures decreasd fairly. It seemed to be beneficial to add kotogenic diet the anticonvulsant therapy for the treatment of minor motor seizure children. We report these results with some discussion and a brief review of related literature
Child
;
Diet
;
Female
;
Humans
;
Infant
;
Infant, Newborn
;
Ketogenic Diet*
;
Male
;
Seizures*
;
Spasms, Infantile
8.The Outcome of Percutaneous Intervention of the Superficial Femoral Artery and the Predictors of its Patency.
Sang Hak LEE ; Donghoon CHOI ; Young Guk KO ; Kihwan KWON ; Do Yun LEE ; Byung Chul CHANG ; Won Heum SHIM
Korean Circulation Journal 2003;33(7):607-613
BACKGROUND AND OBJECTIVES: Percutaneous intervention has become an established technique in the treatment of peripheral arterial obstructive disease. This study was performed to evaluate the procedural success and long-term outcome of percutaneous intervention of the superficial femoral artery (SFA), and to determine the factors that influence the long-term outcome. SUBJECTS AND MEHTODS: Eighty-eight consecutive lesions, in 76 subjects (mean age 65) with chronic lower limb ischemia and SFA obstruction, diagnosed with angiography were included in this study. The angiographic success was defined as residual stenosis <30% and the clinical success as an improvement by at least one clinical category. The clinical patency was defined as an absence of symptom recurrence and target lesion revascularization during the follow up period. The predictors of the outcome were also determined. RESULTS: Balloon angioplasty only was performed in 39 lesions and thrombolysis only in 2, whereas stenting was performed in 47 lesions. Seventy four of the 88 attempts (84%) at recanalization were angiographically successful, while 73 (83%) experienced clinical improvement. The twelve month patency was 67%. Critical ischemia (versus intermittent claudication)(relative risk 4.2, p=0.020) and renal failure (relative risk 4.1, p=0.016) were independent negative predictors of the patency. CONCLUSION: Percutaneous intervention of the SFA yielded a high procedural success rate, with an acceptable long-term outcome. Symptoms of critical ischemia and renal failure were predictive of a low long-term patency.
Angiography
;
Angioplasty
;
Angioplasty, Balloon
;
Arterial Occlusive Diseases
;
Constriction, Pathologic
;
Femoral Artery*
;
Follow-Up Studies
;
Ischemia
;
Lower Extremity
;
Outcome Assessment (Health Care)
;
Recurrence
;
Renal Insufficiency
;
Stents
9.The Influence of the Various Configurations of Lower Lumbar and Lumbosacral Spine on the Disc Degeneration: Multifactorial Analysis.
Chong Suh LEE ; Sung Soo CHUNG ; Saeng Guk LEE ; Min Sup JI ; Yeon Kwon JEONG ; Sang Eun KIM
The Journal of the Korean Orthopaedic Association 1998;33(7):1640-1647
There are some controversies on the mechanism of the lumbar disc degeneration and disc prolapse. But,it is clear that many factors are related to the disc degeneration. Configurations of the lower lumbar and lumbosacral spine have long been proposed as one of the important factors of disc degeneration in these areas. To look for the configurational risk factors and the probability of disc degeneration by the combinations of these factors, we analyzed simple radiographs and MRI of 73 patients who complaints of low back pain and are between 20 years and 39 years of age. We performed chi-square test and multivariate logistic regression analysis: L4-5 disc degeneration and L5-Sl disc degeneration as dependent variables and lumbar lordosis, sacral inclination, height of intercrest line, transitional vertebra and facet joint asymmetry as independent variables. We could not find any of these variables significantly related to the L4-5 intervertebral disc degeneration. For L5-S1 disc degeneration, only the presence of transitional vertebra was signicantly related. When there is no transitional vertebra, the probability of disc degeneration is 9 times(8.889) as large as that of presence of transitional vertebra. The probability of L4-5 disc degeneration without the degeneration of L5-S1 is 3 times as large as that of degeneration of both of L4-5 and L5-S1 disc in case of the presence of transitional vertebra.
Animals
;
Humans
;
Intervertebral Disc Degeneration*
;
Logistic Models
;
Lordosis
;
Low Back Pain
;
Magnetic Resonance Imaging
;
Prolapse
;
Risk Factors
;
Spine*
;
Zygapophyseal Joint
10.Evaluation of Random Urine Sodium and Potassium Compensated by Creatinine as Possible Alternative Markers for 24 Hours Urinary Sodium and Potassium Excretion.
Hyunmin KOO ; Sang Guk LEE ; Jeong Ho KIM
Annals of Laboratory Medicine 2015;35(2):238-241
Sodium and potassium intake was assessed on the basis of its respective excretion levels in 24 hr urine samples. However, owing to the inconvenience of collection, we evaluated random spot urine for alternative sodium and potassium excretion markers. We included 250 patients who submitted 24 hr- and spot urine for clinical tests. However, 22 patients who showed 24 hr urine creatinine excretion levels <500 mg/day were excluded, because these samples possibly resulted from incomplete urine collection. Moreover, 24 patients were excluded because of their use of diuretics during the urine collection period. We observed significant correlations between 24 hr urine sodium excretion and both the sodium/creatinine (r=0.34, P<0.0001) and the sodium/specific gravity unit (SGU) ratios (r=0.19, P=0.007) in random urine samples. Similarly, 24 hr urine potassium excretion and both the spot urine potassium/creatinine (r=0.47, P<0.0001) and potassium/SGU ratios (r=0.28, P<0.0001) were significantly correlated. Although the estimated sodium/creatinine and potassium/creatinine ratios showed a significant correlation with 24 hr urine sodium and potassium excretion, respectively, further studies are required to develop a spot urine test for individualized monitoring of sodium and potassium excretion.
Biomarkers/urine
;
Creatinine/*urine
;
Humans
;
Hypertension/pathology/urine
;
Potassium/*urine
;
Sodium/*urine
;
Urinalysis
;
Urine Specimen Collection