PURPOSE: This study was performed to analyze the clinical characteristics of urologic patients who visited emergency center and provide a fundamental data for further study, and to add some help in the management of the patients. Materials and Methods: Among the total 99,935 patients who visited the emergency center from July 1, 1993 to June 30, 1995, the clinical data of 3,063 urologic patients was reviewed retrospectively. RESULTS: The most common group of age was 4th decade, and male predominated over female by 2.6 : 1. The peak time of patient's entrance to emergency center was between 20 : 00 and 24 : 00 (24.4%) and second peak was 00 : 00 and 04 : 00 (18.5%). Flank pain (57.5%) was the most common symptom and urinary retention (10.3%), gross hematuria (9.7%), irritative voiding symptoms (7.5%) followed that. The common diseases or injury were urinary stone (56.4%) and benign prostatic hyperplasia (8.0%), renal injury (4.0%), acute cystitis (3.7%) respectively. The admission rate was 23.3% and the ratio between urologic department and other departments was 4 : 1. Trauma was occupied 12.5% in all urologic patients and common disease or injuries that needed emergent operation were bladder rupture (23.5%), testicular torsion (18.5%), and renal trauma (16.0%). 7 patients with multiple injury were expired due to 1 urologic cause (renal trauma) and 6 non-urologic causes. CONCLUSIONS: The most common cause that brings the urologic patients to the emergency center is flank pain associated with urinary stone and the factors related to increased occurrence are male, age of 4th decades and midnight.
Cystitis ; Emergencies* ; Female ; Flank Pain ; Hematuria ; Humans ; Male ; Multiple Trauma ; Prostatic Hyperplasia ; Retrospective Studies ; Rupture ; Spermatic Cord Torsion ; Urinary Bladder ; Urinary Calculi ; Urinary Retention

The prognosis of malignant ovarian tumor is poorer than that of borderline malignant ovarian tumor, Therefore an accurate diagnosis and estimation of the biologic behavior of the tumor are necessary for proper management of the patient. The histologic investigation of the tumor may provide information on the estimation of the malignant potential of tumor cells, but it may be a questionable method because of the subjective determination of tumor grade. Quantification of proliferative activity of tumor cells may play a role as an objective method to provide an estimation of the malignant potential of tumor cells. An evaluation of histologic findings was done on 84 cases of ovarian mucinous and serous tumors that were surgically resected and diagnosed during the period from January 1981 through July 1992. The proliferating cell nuclear antigen (PCN A) labelling index estimated from the immunohistochemical stain for PCN A and the Sphase fraction and porliferative index obtained from flow cytometric DN A analysis were assessed each other with histologic findings. The results are as follows: The presence of aneuploidy in malignant tumors was statistically significant as compared with benign tumors. The borderline malignant tumors showed no significant difference between the number of diploidy and aneuploidy. The PCNA labelling index, S-phase fraction and proliferative index tended to increase as the histologic grade of tumors went up. They were higher in malignant tumors than in others. The PCN A labelling index, S-phase fraction and proliferative index were higher in tumors with aneuploidy than in those with diploidy. In contrast to borderline malignant tumors, the PCNA labelling index in malignant tumors revealed a significant relation with the mitotic index. The S-phase fraction and proliferative index showed, in malignant tumors, a close correlation with the architectural grade and nucleolar grade, but not in borderline malignant tumors. Considering these results, the presence of aneuploidy, PCNA label.

29 isoniazid (INH) resistant isolated strains and INH sensitive reference strain (H37Rv) of Mycobacterium tuberculosis were analysed by polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) and NciI restriction mapping for the detection of mutations in katG gene and inhA gene. The katG gene was divided into 3 parts (Akat, Bkat, Ckat; each part is about 800 bp) and amplified, inhA gene was amplified as a whole. Each of the amplified 800 bp DNA was digested into small fragments of less than 400 bp with restriction enzymes for the direct PCR-SSCP analysis. Firstly, 10 strains were analysed. All the 10 isolates showed clearly distinct SSCP patterns in Bkat from that of the reference strain, but only two isolates showed distinct SSCP patterns in Akat, and no isolated strain showed any distinct SSCP patterns in Ckat. 10 isolates also showed distinct SSCP patterns in inhA. NciI restriction mapping of Bkat showed mutation in codon 463 in 7 strains among 10 isolated strains. With these results an early detection strategy for the INH resistant M. tuberculosis was applied to the rest of 19 isolated INH resistant strains. Firstly, isolates were screened by Ncsl mapping in Bkat, and 13 strains showed mutations in codon 463. Secondly, the rest of 6 INH resistant isolates were analysed by PCR-SSCP with restriction enzyme digestion (PCR-SSCP-RE) in Bkat, and all the strains showed distinct SSCP patterns from that of the INH sensitive reference strain. This proved our strategy as effective and economic and time saving method in early detection of INH resistant M. tuberculosis.
Codon ; Diagnosis* ; Digestion ; DNA ; Isoniazid* ; Korea* ; Mycobacterium tuberculosis* ; Mycobacterium* ; Polymorphism, Single-Stranded Conformational ; Restriction Mapping ; Tuberculosis

Emphysematous urinary tract infection is a rare, life-threatening necrotizing infection characterized by gas generation, and usually occurs in patients with diabetes and/or urinary tract obstruction. We herein report a unique case of emphysematous renal infection occurred in. an old diabetic man with renal cell carcinoma. This case suggests that renal cell carcinoma should be also considered a rare cause of emphysematous renal infection showing mass contour.
Carcinoma, Renal Cell* ; Humans ; Urinary Tract ; Urinary Tract Infections

33 cases of prostatic carcinoma admitted during the 10 years period from August 1970 through July 1980, were observed clinically 1. The age distribution ranged from 48 to 85 years with the common age groups in the 7th and 8th decades. 2. Prostatic biopsy was performed transurethraIly in 14 cases, and transperineal needle biopsy followed by transurethral resection was performed in 10 cases. 3. Serum acid phosphatase activity was elevated in 14 cases and 8 cases were found to have distant metastasis. 4. Orchiectomy was done in 15 cases immediately following biopsy report of adenocarcinoma, estrogen therapy was done in 7 cases, and radiation therapy was done in 3 cases of in the cases of distant metastasis. 5. Observation was followed up in 18 cases from 1 month through 57 months clinically.
Acid Phosphatase ; Adenocarcinoma ; Age Distribution ; Biopsy ; Biopsy, Needle ; Estrogens ; Humans ; Neoplasm Metastasis ; Orchiectomy

Bartter's syndrome is a rare tubular disorder characterized by hypokalemic, hypochloremic metabolic alkalosis, hyperreninemic hyperaldosteronism, hyporesponsiveness to pressor agents, and juxtaglomerular apparatus hyperplasia. We report here a case of Bartter's syndrome in a 5 month-old male infant who improved with potassium supplements. In addition to a case report, brief review of related literatures was done.
Alkalosis ; Bartter Syndrome* ; Humans ; Hyperaldosteronism ; Hyperplasia ; Infant ; Juxtaglomerular Apparatus ; Male ; Potassium

A Clinical observation was made of 20 cases of testicular tumor admitted to the Department of Urology, Kei-myung University Medical College and Hospital during the period from May 1971 through July 1982. Among the 20 cases, 4 cases were transferred to this department for further treatment and tumor recurrence following orchiectomy. The results of clinical observation are summarized as below: 1. Age distribution was between 9 months and 57 years old, showing the highest incidence below 10 years old (65%). 2. There were 7 cases of teratoma, 5 cases of seminoma, 5 cases of embryonal carcinoma, 1 case of teratocarcinoma and 2 cases of metastatic neoplasm. 3. Stages of primary germ cell tumors; stage A 6 cases, stage B 2 cases and stage C 3 cases. 4. These patients were managed by surgery, radiation therapy and chemotherapy according to the histologic findings and clinical stages.
Age Distribution ; Carcinoma, Embryonal ; Child ; Drug Therapy ; Humans ; Incidence ; Middle Aged ; Neoplasms, Germ Cell and Embryonal ; Orchiectomy ; Recurrence ; Seminoma ; Teratocarcinoma ; Teratoma ; Urology

External fixation is regarded as the treatment of choice for type 2 and 3 open tibial fractures. However, external fixation alone, especially of an unstable fracture, can be complicated by high incidence of malunion, delayed union, loss of reduction, refracture, and pin-tract infection. Some surgeons tried to treat such problems by secondary intramedullary nailing, but they came to different results. The purpose of the present study is to eveluate our experience with secondary intramedullary nailing after external fixation of 6 cases of type 3B open tibia fractures and 1 case of type 3B femur fracture. These cases were followed for more than 13 months and the following results were obtained. 1. The external fixation had been maintained for an average of 62 days. 2. The mean interval between removal of the external fixator and intramedullary nailing was 23 days. 3. Antibiotics was injected for 2 weeks after removal of external fixator. 4. Reamed intramedullary nailing with static interlocking were done in all 13 cases. 5. Deep infections developed in 2 cases, one case which had been pin-tract infection was around intramedullary nail and the other in fracture site. 6. All cases were healed ultimately and average union time after nailing was 9 months.
Anti-Bacterial Agents ; External Fixators ; Femur ; Fracture Fixation, Intramedullary ; Fractures, Bone ; Incidence ; Surgeons ; Tibia ; Tibial Fractures

Popliteal pterygium syndrome is rare, with 60 cases described in the literature. The syndrome includes a popliteal web extending from the ischium to the heel and other abnormalities including toenail dysplasia, deformities of the foot and toes, and oral cavity abnormalities. The main orthopedic problem is a flextion contracture of the knee and an equinus foot. We experienced a six-month-old girl with popliteal pterygium, in whom resection of abnormal fibrotic muscle belly, Achilles tendon legnthening, and Z-plastic lengthening of the skin resulted in partial correction of flexion deformity of the knee and equines contracture of the foot at one year follow-up.
Achilles Tendon ; Congenital Abnormalities ; Contracture ; Female ; Follow-Up Studies ; Foot ; Heel ; Humans ; Ischium ; Knee ; Mouth ; Nails ; Orthopedics ; Pterygium ; Skin ; Toes

Allergic rhinitis is chronic disorder of nose which is evoked by IgE-mediated inflammation mostly triggered by contact between nasal mucosa and inhalant allergen. Allergic rhinitis can be classified according to seasonality (seasonal or perennial), continuity (intermittent or persistent), and severity (mild, moderate, or severe). Allergic rhinitis is relatively common, and the prevalence of allergic rhinitis has increased in Korea like other countries. As well as the prevalence of allergic rhinitis, the indoor and outdoor concentration of inhalant allergens and the sensitization to inhalant allergens were systematically investigated in Korea. As a result, house dust mite, pollens, fungal spores, cockroach, and animal hairs were found to be common inhalant allergens. Moreover, the concentration of tree pollens and grass pollens and sensitization to those pollens increased because of global warming, which may consequently increase the prevalence of pollen-induced allergic rhinitis. With regard to socioeconomic burden of allergic rhinitis, the direct medical cost including herbal and alternative medicine was as high as 1.78 million Korean won per year. Direct nonmedical cost as well as indirect cost including unproductivity, absenteeism, and medical cost for associated diseases such as asthma worsened the socioeconomic burden of allergic rhinitis.
Absenteeism ; Allergens ; Animals ; Asthma ; Classification* ; Cockroaches ; Complementary Therapies ; Epidemiology* ; Global Warming ; Hair ; Inflammation ; Korea ; Nasal Mucosa ; Nose ; Poaceae ; Pollen ; Prevalence ; Pyroglyphidae ; Rhinitis* ; Rhinitis, Allergic, Perennial ; Seasons ; Spores, Fungal