1.The effect of bacterial endotoxin on the synthesis and metabolism of prostaglandin E2 by human amnion cells.
Korean Journal of Obstetrics and Gynecology 1992;35(12):1810-1822
No abstract available.
Amnion*
;
Dinoprostone*
;
Humans*
;
Metabolism*
3.A case of giant cell tumor of tendon sheath.
Gil Ju YI ; Yong Sang KIM ; Chil Whan OH
Korean Journal of Dermatology 1993;31(3):416-420
Giant cell tumor of tendon sheath(GCTTS) is a benign mesenchymal lesion composed of cytologically bland mononuclear cells admixed with multinucleated giant cells. Our report describes the clinical and pathologic features of a 36-year-old female's tumor with a two years history over the lateral side of the left little finger, Especially, we could observe the characteristic thre types of cells in an electromicroscopic study, histiocyte-like cells, fibroblast-like cells and multinucleated giant cells. In lmmunohistochemical studies, we demonstrated that the tumor cells of GCTTS exhibit a phenotype consistent with histiocyte differentiated to Langerhan's cell.
Adult
;
Fingers
;
Giant Cell Tumors*
;
Giant Cells*
;
Histiocytes
;
Humans
;
Phenotype
;
Tendons*
4.Brodie's Abscess: A Case Report
Hyung Seok KIM ; Ki Sung HONG ; Sang Hoon GIL
The Journal of the Korean Orthopaedic Association 1982;17(6):1233-1236
Brodie's abscess is a primary subacute pyogenic osteomyelitis that has a thin wall of fibrous tissue and sclerotic bone. The authors have encountered a case of a Brodie's abscess that was developed in the same place of both tibia at the same time and treated the case with surgery and continuous closed irrigation.
Abscess
;
Osteomyelitis
;
Tibia
5.IS6110 based DNA Fingerprinting of Mycobacterium tuberculosis Isolated from The Nationwide Tuberculosis Prevalence Survey in 1995.
Sang Jae KIM ; Young Kil PARK ; Sang Hyun CHO ; Gil Han BAI ; Yeun KIM
Journal of the Korean Society for Microbiology 1998;33(5):475-484
One hundred and thirty-eight strains of Mycobacterium tuberculosis isolated from the 7th nationwide tuberculosis prevalence survey in 1995 were subjected to the restriction fragment length polymorphism (RFLP) analysis using IS6110 probe to define the representative fingerprinting patterns of Korean strains of M. tuberculosis and to evaluate the usefulness of DNA fingerprinting in tracing the transmission link of M. tuberculosis. Among 138 strains, 129 different IS6l10 RFLP types were identified. The number of bands in IS6110 RFLP types diversed from 1 to 20, and the majority (75%) was 9 to 14 bands. The RFLP patterns of 8 out of 15 strains isolated from the follow-up survey of one and half year later after the 7th national TB prevalence survey were unchanged when compared with previous RFLP patterns. Fifteen (11%) out of 138 strains were grouped in 6 IS6110 clusters; 2 with 10 copies, 2 with 12 copies, 1 with 14 copies, and 1 with 17 copies. These clusters were unable to be subclassified by IS1081 or (GTG) probes except one cluster by pTBN12 probe. The transmission links of 2 clusters were deducible; one from household and another from neighborhood, but those of remaining clusters were unclear because they had no contact one another. The results suggest that vigorous transmissions in tuberculosis are still progressing in Korea.
Dermatoglyphics
;
DNA Fingerprinting*
;
DNA*
;
Family Characteristics
;
Follow-Up Studies
;
Korea
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymorphism, Restriction Fragment Length
;
Prevalence*
;
Residence Characteristics
;
Tuberculosis*
6.Rapid Diagnosis of Isoniazid Resistance by Detection of Mutations in katG and inhA of Mycobacterium tuberculosis from Korea.
Sang Jae KIM ; Seok Yong KIM ; Ji Youn LEE ; Sang Ryeol RYU ; Gil Han BAI
Journal of the Korean Society for Microbiology 1997;32(5):569-576
29 isoniazid (INH) resistant isolated strains and INH sensitive reference strain (H37Rv) of Mycobacterium tuberculosis were analysed by polymerase chain reaction-single strand conformational polymorphism (PCR-SSCP) and NciI restriction mapping for the detection of mutations in katG gene and inhA gene. The katG gene was divided into 3 parts (Akat, Bkat, Ckat; each part is about 800 bp) and amplified, inhA gene was amplified as a whole. Each of the amplified 800 bp DNA was digested into small fragments of less than 400 bp with restriction enzymes for the direct PCR-SSCP analysis. Firstly, 10 strains were analysed. All the 10 isolates showed clearly distinct SSCP patterns in Bkat from that of the reference strain, but only two isolates showed distinct SSCP patterns in Akat, and no isolated strain showed any distinct SSCP patterns in Ckat. 10 isolates also showed distinct SSCP patterns in inhA. NciI restriction mapping of Bkat showed mutation in codon 463 in 7 strains among 10 isolated strains. With these results an early detection strategy for the INH resistant M. tuberculosis was applied to the rest of 19 isolated INH resistant strains. Firstly, isolates were screened by Ncsl mapping in Bkat, and 13 strains showed mutations in codon 463. Secondly, the rest of 6 INH resistant isolates were analysed by PCR-SSCP with restriction enzyme digestion (PCR-SSCP-RE) in Bkat, and all the strains showed distinct SSCP patterns from that of the INH sensitive reference strain. This proved our strategy as effective and economic and time saving method in early detection of INH resistant M. tuberculosis.
Codon
;
Diagnosis*
;
Digestion
;
DNA
;
Isoniazid*
;
Korea*
;
Mycobacterium tuberculosis*
;
Mycobacterium*
;
Polymorphism, Single-Stranded Conformational
;
Restriction Mapping
;
Tuberculosis
8.Clinical analysis of contact Nd:YAG laser tonsillectomy.
Hang PARK ; Seok Kyung HONG ; Byung Sang HAN ; Young Ho HONG ; Hoon KIM ; Chun Gil KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(3):372-380
No abstract available.
Tonsillectomy*
9.Experimental study of salivary gland stone fragmentation byextracorporeal shock wave lithotripsy.
Seok Kyung HONG ; Byung Sang HAN ; Hang PARK ; Young Ho HONG ; Hoon KIM ; Chun Gil KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(5):626-631
No abstract available.
Lithotripsy*
;
Salivary Gland Calculi*
;
Salivary Glands*
;
Shock*
10.Clinical Significance of MRI in Hypoxic-Ischemic Encephalopathy During Neonatal Period.
Dong Joon KIM ; Sang Hee KIM ; Kye Hwan SEOL ; Gil Hyun KIM ; Hak Soo LEE
Journal of the Korean Pediatric Society 1997;40(12):1731-1736
PURPOSE: Hypoxic-ischemic encephalopathy is a major neurologic problem and one of the most important perinatal causes of neurological morbidity. Evaluation of the presence, extent, and subsequent evolution of hypoxic-ischemic lesions may be very important. We studied the significance of imaging modality through the analysis of brain MRI findings of hypoxic-ischemic encephalopathy during neonatal period and comparison with findings of brain ultrasonography. METHODS: We analysed the forty-seven infants retrospectively who were diagnosed as hypoxic-ischemic encephalopathy and underwent brain MRI and ultrasonography from Jan. 1992 to May 1996. RESULTS: 1) The mean gestational age and birth weight of the twenty-seven infants who were premature were 32.8+/-2.08weeks and 1.97+/-0.44kg respectively. The mean gestational age and birth weight of twenty infants who were fullterm were 39.3+/-1.04weeks and 2.98+/- 0.93kg respectively. The primary hypoxic-ischemic insults occurred during antenatal, intrapartum and postnatal period. 2) The findings of brain MRI were classified into periventricular leukomalacia, encephalomalacia, basal ganglia lesion, focal parenchymal hemorrhage, ventriculomegaly without other lesion and normal finding. 3) Three infants among twenty-five infants with periventricular leukomalacia, four infants among seven infants with basal ganglia lesion and six infants among seven infants with focal parenchymal hemorrhage were not diagnosed by brain ultrasonography. 4) All of ten infants with encephalomalacia and four infants with ventriculomegaly without other lesion were diagnosed by brain ultrasonography. CONCLUSIONS: MRI can diagnose the hypoxic-ischemic lesions which would not be possible by brain ultrasonography. Therefore MRI is the imaging modality of choice for diagnosis in infants with hypoxic-ischemic encephalopathy. We believe that the benefits of MRI outweigh its somewhat higher cost, lack of portability and monitoring difficulties.
Basal Ganglia
;
Birth Weight
;
Brain
;
Diagnosis
;
Encephalomalacia
;
Gestational Age
;
Hemorrhage
;
Humans
;
Hypoxia-Ischemia, Brain*
;
Infant
;
Infant, Newborn
;
Leukomalacia, Periventricular
;
Magnetic Resonance Imaging*
;
Retrospective Studies
;
Ultrasonography