2.Combined Treatment of Staghorn Calculi by Percutaneous Nephrolithotomy and Extracorporeal Shock Wave Lithotripsy.
In Gi SEOUNG ; Seung Chul YANG ; Moo Sang LEE
Korean Journal of Urology 1988;29(6):917-923
On the 59 cases of staghorn calculi treated at our institution with either ESWL monotherapy or initial percutaneous nephrolithotomy followed by ESWL between July 1987 and June 1988, 50 cases(22 complete and 28 partial staghorns) have adequate follow up. Using a retrospective cohort design, patients were matched for age, sex, stone size, stone complexity, renal function, urinary tract infection and urinary tract obstruction. Twenty five pairs of combination therapy and ESWL monotherapy patients with complete data were matched. The groups were not significantly different in the matching parameters. A significantly higher stone free rate follows combination therapy versus ESWL monotherapy for complete staghorns(25% vs. 0% in the case of 1 time ESWL treatment : 76% vs. 40% at 3 months follow up visit but the difference is slight for partial staghorns(54% vs. 47% in the case of 1 time ESWL treatment ; 85% vs. 73% at 3 months follow up visit). Both have similar length of hospital stay for complete staghorns(15 days vs. 14 days), but a significantly longer hospital stay follows combination therapy for partial staghorns(13 days vs. 6 days). The morbidity of the combination approach is not greater than that of ESWL monotherapy(40% vs. 36%), where as the need for axillary procedures is significantly lower in this group(16% vs. 36%). Our results indicate that virtually all staghorn calculi are best treated with initial percutaneous nephrolithotomy followed by ESWL. This approach allows for chemolysis and secondary procedures. But small volume partial staghorns in nondilated systems may be considered for ESWL monotherapy with ureteral stenting.
Calculi*
;
Cohort Studies
;
Follow-Up Studies
;
Humans
;
Length of Stay
;
Lithotripsy*
;
Nephrostomy, Percutaneous*
;
Retrospective Studies
;
Shock*
;
Stents
;
Ureter
;
Urinary Tract
;
Urinary Tract Infections
3.Bronchiectasis: HRCT vs bronchography.
Sang Hoon CHA ; Jung Gi IM ; Yang Min KIM ; Man Chung HAN ; Young Soo SHIM
Journal of the Korean Radiological Society 1991;27(5):632-636
No abstract available.
Bronchiectasis*
;
Bronchography*
4.Clinical analysis of rhinoplasty.
Yang Gi MIN ; Pil Sang CHUNG ; Keun Ho CHANG ; Jong Woo LEE
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(3):443-449
No abstract available.
Rhinoplasty*
5.The study of the left ventricular diastolic function in the patients with dilated cardiomyopathy.
Gi Sang KANG ; Il PARK ; Jung Ha PARK ; Chang Ho YANG ; Sun Taek KIM ; Jong Seong KIM
Korean Journal of Medicine 1993;45(2):220-227
No abstract available.
Cardiomyopathy, Dilated*
;
Humans
6.Primary Osteosarcoma of the Sphenoid Bone: Case Report.
Geun Jin YANG ; Mun Chul KIM ; Hoon CHUNG ; Sang Pyung LEE ; Gi Hwan CHOI ; Hyung Tae YEO
Journal of Korean Neurosurgical Society 2000;29(5):680-683
No abstract available.
Osteosarcoma*
;
Sphenoid Bone*
7.Clinical Roles of Continuous Lumbar Drainage in Acute Hydrocephalus Patients.
Geun Jin YANG ; Mun Chul KIM ; Hoon CHUNG ; Sang Pyung LEE ; Gi Whan CHOI ; Hyung Tae YEO
Journal of Korean Neurosurgical Society 2000;29(5):644-649
No abstract available.
Drainage*
;
Humans
;
Hydrocephalus*
8.A Case of Adrenal adenoma Associated with Pregnancy
Jung Gyn KIM ; Jang Sik CHOO ; Yang Kyu LEE ; Bung Chul HAN ; Seung Bum JIN ; Sang Gi YANG ; Chang Sup SONG ; Me Gyung SIN
Journal of Korean Society of Endocrinology 1994;9(1):39-45
We experienced a case of aldosterone and cortisol secreting adrenal adenoma associated with pregnancy in a 23 year old female patient.The patient complained of severe thoraco-lumbar pain, weight gain, sweating, anxiety, and mild abdominal discomfort. On physical findings, hypertension, tachycardia, facial plethora, moon face, buffalo hump and truncal obesity were found.
Adenoma
;
Aldosterone
;
Anxiety
;
Buffaloes
;
Female
;
Humans
;
Hydrocortisone
;
Hypertension
;
Moon
;
Obesity
;
Pregnancy
;
Sweat
;
Sweating
;
Tachycardia
;
Weight Gain
9.Chemical Constituents Identified from Fruit Body of Cordyceps bassiana and Their Anti-Inflammatory Activity.
Wonse SUH ; Gyeongsug NAM ; Woo Seok YANG ; Gi Ho SUNG ; Sang Hee SHIM ; Jae Youl CHO
Biomolecules & Therapeutics 2017;25(2):165-170
Cordyceps bassiana is one of Cordyceps species with anti-oxidative, anti-cancer, anti-inflammatory, anti-diabetic, anti-obesity, anti-angiogenic, and anti-nociceptive activities. This mushroom has recently demonstrated to have an ability to reduce 2,4-dinitrofluorobenzene-induced atopic dermatitis symptoms in NC/Nga mice. In this study, we further examined phytochemical properties of this mushroom by column chromatography and HPLC analysis. By chromatographic separation and spectroscopic analysis, 8 compounds, such as 1,9-dimethylguanine (1), adenosine (2), uridine (3), nicotinamide (4), 3-methyluracil (5), 1,7-dimethylxanthine (6), nudifloric acid (7), and mannitol (8) were identified from 6 different fractions and 4 more subfractions. Through evaluation of their anti-inflammatory activities using reporter gene assay and mRNA analysis, compound 1 was found to block luciferase activity induced by NF-κB and AP-1, suppress the mRNA levels of cyclooxygenase (COX)-2 and tumor necrosis factor (TNF)-α. Therefore, our data strongly suggests that compound 1 acts as one of major principles in Cordyceps bassiana with anti-inflammatory and anti-atopic dermatitis activities.
Adenosine
;
Agaricales
;
Animals
;
Chromatography
;
Chromatography, High Pressure Liquid
;
Cordyceps*
;
Dermatitis
;
Dermatitis, Atopic
;
Fruit*
;
Genes, Reporter
;
Luciferases
;
Mannitol
;
Mice
;
Niacinamide
;
Prostaglandin-Endoperoxide Synthases
;
RNA, Messenger
;
Transcription Factor AP-1
;
Tumor Necrosis Factor-alpha
;
Uridine
10.Toxicity of Polylactic Acid Polymer in the Treatment of Paranasal Sinusitis.
Yang Gi MIN ; Young Ki KIM ; Sea Young JEON ; Ki Sang RHA ; Seo Young JEONG
Journal of Rhinology 1997;4(2):104-110
The authors, after inducing acute sinusitis in rabbits, compared cases where we opened the natural ostium and a general dose of administered antibiotics and cases where we opened the natural ostium and locally administered dose of antibiotics using polymer, and found that the application of local antibiotics using polymer is the superior of the two in treating sinusitis. To be able to develop a treatment for sinusitis using antibiotics incorporating polymer, we first need to examine the toxicity of polymer. The purpose of this study was to examine the toxicity of polymer through a general toxicity test as well as a special toxicity test in experiments using animals. As a result of this study, we discovered that poly-L-lactic acid (PLA) polymer works as an intraperitoneal foreign body and causes adhesion of viscera, but nethier acute nor subacute toxicity of PLA polymer was detected, and no negative effect on reproductive function was observed. It was also observed to induce neither immune reaction such as hypersensitivity nor local toxicity to the maxillary sinus mucosa of rabbit. We conclude that the results of this study can provide basic information for developing antibiotics-incorporating PLA polymer for the treatment of sinusitis and for clinical experiments involving such antibiotics.
Animals
;
Anti-Bacterial Agents
;
Foreign Bodies
;
Hypersensitivity
;
Maxillary Sinus
;
Mucous Membrane
;
Polymers*
;
Rabbits
;
Sinusitis*
;
Toxicity Tests
;
Viscera