1.Clinical evaluation of mitral valve replacement.
Sang Hyung KIM ; Jeong Gi JEONG
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(9):861-869
No abstract available.
Mitral Valve*
2.Function of bcl-X proteins in Nitric Oxide-induced Apoptosis in RAW 264.7 Macrophages.
Sang Gi PAIK ; Young Sang KIM ; Joo Young IM ; Jeong Heon YOON
Korean Journal of Immunology 1999;21(3):229-236
LPS and IFN-r induce nitric oxide synthase in macrophages and the resultant NO causes apoptotic cell death in the activated macrophages. NO production and apoptosis were inhibited by N-monomethyl L-arginine (NMMA), a competitive inhibitor of NO synthase. To study the role of BCL-X proteins, RAW 264.7 cells were transfected with the expression vectors with human bcl-Xl or bcl-Xs cDNAs, respectively. Stable transfectants were selected and confirmed by RT-PCR. NO production in response to LPS and IFN-r caused apoptosis in RAW 264.7 cells and vector transfected control cells within 24 hr. Both NO production and apoptosis were inhibited by N(G)-monomethyl L-arginine (NMMA). In contrast, bcl-Xs transfectant appeared slightly susceptible and bcl-X(L)< transfectant appeared slightly resistant, although NO production was similar to control cells. These results suggest that bcl-X proteins play roles in both positive and negative regulation of apoptosis induced by NO.
Apoptosis*
;
Arginine
;
bcl-X Protein*
;
Cell Death
;
DNA, Complementary
;
Humans
;
Macrophages*
;
Nitric Oxide
;
Nitric Oxide Synthase
3.EFFECT OF VARIOUS GROWTH FACTORS IN CULTURE OF EAR CHONDROCYTES OF RABBIT.
Sang Hoon HAN ; Jeong Hoon KANG ; Chang Gi SUNG ; Jae Dam LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1997;24(5):884-892
No abstract available.
Chondrocytes*
;
Ear*
;
Intercellular Signaling Peptides and Proteins*
4.The Smoking Status and Its Associated Factors of Some Army Soldiers.
Sang Jo JEONG ; Cheol Gab LEE ; So Yeon LYU ; Gi Sun KIM
Tuberculosis and Respiratory Diseases 2001;51(5):426-436
OBJECTIVE: This study was performed to determine the smoking status and its associated factors in military life among young Korean men to provide date for smoking prevention in military areas as a part of the health promotion program for soldiers. METHODS: 1,033 infantrymen serving in 17 military units, which are located in suburbs of K city, were enrolled in this study. A questionnaire on the soldiers smoking status and other various characteristics was obtained from October 2nd to 12th, 2000. Logistic regression analysis was performed on the various variables in order to determine the factors related to smoking. RESULTS: 1) 830(80.3%) out of 1033 subjects had smoked cigarettes and 759 persons(73.4%) were regular smokers. 2) Among the 734 soldiers who started smoking before their military service, 714 soldiers(97.2%) continued to smoke after, while 45 soldiers(15.0%) among the 299 non-smokers started smoking after joining the army. 3) Through the logistic regression analysis, the education level, specialty in the army, smoking amongst the friends they met before military service, smoking amongst soldiers in the army, dating girl friends, drinking, satisfaction with their army lives and the presence of convenient smoking places at the barracks were significant factors related to the prevalence of smoking in soldiers. CONCLUSION: the factors related with incidence of smoking in the army are the complicated interactions among the individuals personal background, general charcterisitcs of the solider and the special environment in the barracks. Therefore, to improve national soldiers' health, an active non-smoking campaign and education should be pushed to discourage smoking in the barracks.
Drinking
;
Education
;
Female
;
Friends
;
Health Promotion
;
Humans
;
Incidence
;
Logistic Models
;
Male
;
Military Personnel*
;
Prevalence
;
Smoke*
;
Smoking*
;
Tobacco Products
5.Clinical and Histological Analysis of 126 Cases of Gastric Polyps.
Jung Myung CHUNG ; Sang Hyuk LEE ; Sang Yong SEOL ; Gi Jeong CHO ; Hyoung Gyu SHIN ; Kil Hyon CHO
Korean Journal of Gastrointestinal Endoscopy 1995;15(1):40-45
The gastrointestinal polyp is a premalignant lesion in varying degree. According to the size, the pathology and the location of polyps, it should be removed. Polyps in the gastrointestinal tract can be removed by surgical excision, electrosurgery, cryotherapy, regional radiotherapy and laser therapy with some limitations. Considerable advance in therapeutic endoscopy as well as in diagnostic endoscopy along with newly developed instruments has now made it possible to excise gastrointestinal polyps by means of high frequency generator. We have underwent endoscopic polypectomy, strip biopsy and "O" ring ligation on gastric polyps in 112 patients who visited in this hospital from July l988 to January 1994, and the clinical characteristics including histopathology has been evaluated. Removed polyps were variable in size from less than 0.5 cm up to 4cm. Finally, we concluded that endoscopic polypectomy is a safe and relativly simple procedure and postpolypectomy complication can be considerably reduced by conservative antiulcer therapy.
Biopsy
;
Cryotherapy
;
Electrosurgery
;
Endoscopy
;
Gastrointestinal Tract
;
Humans
;
Laser Therapy
;
Ligation
;
Pathology
;
Polyps*
;
Radiotherapy
6.Treatment of Cerebral Arteriovenous Malformations by Preoperative Embolization and Microsurgery.
Kyu Hong KIM ; Myung Ho RHO ; Woon Gi LEE ; Jeong Hoon CHOI ; In Chang LEE ; Sang Do BAE
Journal of Korean Neurosurgical Society 2000;29(4):500-506
No abstract available.
Intracranial Arteriovenous Malformations*
;
Microsurgery*
7.Role of PET Scan in Gastric Cancer as a Diagnostic Tool.
Gi Jeong CHEON ; Byung Il KIM ; Sang Moo LIM
Journal of the Korean Gastric Cancer Association 2002;2(4):184-190
Clinical application of positron emission tomography (PET) is rapidly increasing for the detection and staging of cancer at whole-body studies performed with the glucose analogue tracer 2-[fluorine-18]fluoro-2-deoxy-D-glucose (FDG). Although FDG PET cannot match the anatomic resolution of conventional imaging techniques in gastrointestinal and abdominal organs, it is particularly useful for identification and characterization of whole body at the same time. FDG PET can show foci of metastatic disease that may not be apparent at conventional anatomic imaging and can aid in the characterization of indeterminate soft-tissue masses. Most gastrointestinal cancer need to surgical management. FDG PET can improve the selection of patients for surgical treatment and thereby reduce the morbidity and mortality associated with inappropriate surgery. FDG PET is also useful for the early detection of recurrence and the monitoring of therapeutic effect. The gastrointestinal cancers, such as gastroesophageal cancer, colorectal cancer, liver cancer and pancreatic cancer, are common malignancies in Korea. PET is one of the most promising and useful methodology for the management of gastric cancer as well as other gastrointestinal cancers.
Colorectal Neoplasms
;
Gastrointestinal Neoplasms
;
Glucose
;
Humans
;
Korea
;
Liver Neoplasms
;
Mortality
;
Pancreatic Neoplasms
;
Positron-Emission Tomography*
;
Recurrence
;
Stomach Neoplasms*
8.FDG-PET/CT Complements Bone Scan with Respect to the Detection of Skip Metastasis of Osteosarcoma: A Case Report.
Gi Jeong CHEON ; Jae Gol CHOE ; In Jung CHAE ; Dae Hee LEE ; Sang Heon SONG ; Myo Jong KIM ; Jong Hoon PARK
The Journal of the Korean Bone and Joint Tumor Society 2012;18(1):45-49
Skip lesion is not uncommon feature in osteosarcoma and considered to be importantly associated with poor prognosis factor, and thus, should be excised with the main mass. The accurate pre-operative evaluation of the intramedullary extent of osteosarcoma is essential, because it determines the level of bone resection. Among the reliable detection methods, bone scan has a drawback of high rate of false negative results and regional MRI has a difficulty to cover the whole involved lesions without clinical suspicion. The authors report a case of osteosarcoma of the distal femur with a proximal skip lesion that was not detected by either regional MR imaging or by bone scan, but which was visualized by FDG-PET/CT.
Complement System Proteins
;
Femur
;
Neoplasm Metastasis
;
Osteosarcoma
;
Prognosis
9.A clinical study of the unstable pelvic bone fracture using slatis trapezoid compression frame.
Yong Girl LEE ; Sang Su DO ; Seung Gi JEONG ; Hyung Joo KIM ; Byung Guk KIM ; Heung Seek PARK
The Journal of the Korean Orthopaedic Association 1991;26(1):317-323
No abstract available.
Pelvic Bones*
10.Cardiac Magnetic Resonance Imaging Findings and Clinical Features of COVID-19 Vaccine-Associated Myocarditis, Compared With Those of Other Types of Myocarditis
Sang Gyun KIM ; Jeong Yeop LEE ; Won Gi JEONG ; Jong Eun LEE ; Yun-Hyeon KIM
Journal of Korean Medical Science 2024;39(4):e42-
Background:
To compare the clinical and cardiac magnetic resonance (CMR) imaging findings of coronavirus disease 2019 (COVID-19) vaccine-associated myocarditis (VAM) with those of other types of myocarditis.
Methods:
From January 2020 to March 2022, a total of 39 patients diagnosed with myocarditis via CMR according to the Modified Lake Louise criteria were included in the present study. The patients were classified into two groups based on their vaccination status:COVID-19 VAM and other types of myocarditis not associated with COVID-19 vaccination.Clinical outcomes, including the development of clinically significant arrhythmias, sudden cardiac arrest, and death, and CMR imaging features were compared between COVID-19 VAM and other types of myocarditis.
Results:
Of the 39 included patients (mean age, 39 years ± 16.4 [standard deviation]; 23 men), 23 (59%) had COVID-19 VAM and 16 (41%) had other types of myocarditis. The occurrence of clinical adverse events did not differ significantly between the two groups. As per the CMR imaging findings, the presence and dominant pattern of late gadolinium enhancement did not differ significantly between the two groups. The presence of high native T1 or T2 values was not significantly different between the two groups. Although the native T1 and T2 values tended to be lower in COVID-19 VAM than in other types of myocarditis, there were no statistically significant differences between the native T1 and T2 values in the two groups.
Conclusion
The present study demonstrated that the CMR imaging findings and clinical outcomes of COVID-19 VAM did not differ significantly from those of other types of myocarditis during hospitalization.