1.Bone Health Knowledge, Self-Efficacy, and Behaviors in Middle-Aged Korean Women.
Eui Geum OH ; Jae Yong YOO ; Jung Eun LEE ; Il Sun KO ; Sang Hui CHU
Korean Journal of Health Promotion 2012;12(2):90-99
BACKGROUND: With the rapid growth of the elderly population, osteoporosis has become a major health problem worldwide. Although health knowledge and self-efficacy are important assets to facilitate healthy behaviors and disease prevention, such information as it relates to individuals and their bone health is limited. The purpose of this study was to assess the levels of knowledge, self-efficacy, and health behaviors on promoting bone health in middle-aged Korean women. METHODS: This is a cross-sectional survey study. A convenience sampling of middle-aged women (> or =40 years) was done at a community health center in Korea. Bone mineral density was measured by dual energy X-ray absorptiometry with the DEXXUM T. The level of knowledge was measured with the Knowledge of Osteoporosis Scale, and self-efficacy with the Osteoporosis Self-efficacy Scale. A questionnaire for bone health behaviors was developed for this study. Collected data were analyzed through descriptive methods, independent t-test, analysis of variance, and Pearson's correlation analysis. RESULTS: A total of 150 middle-aged women whose mean age was 59.8+/-11.5 years participated in the study. Most (74%) were menopausal. Less than one-quarter of participants (22.7%) had osteoporosis and less than half (42%) had osteopenia based on the T-score at the left femur neck site. Level of knowledge (mean score, 10.35) and self-efficacy (mean score, 47.67) ranged from low to moderate. Intake of calcium and vitamin D-rich foods was insufficient in our subjects. Bone health behaviors had significant positive relationships with knowledge (r=0.22, P=0.008) and self-efficacy (r=0.29, P<0.001) on promoting bone health. CONCLUSIONS: These results indicate that educational interventions are needed to enhance knowledge and confidence and to encourage middle-aged women to engage in bone health behaviors.
Absorptiometry, Photon
;
Aged
;
Bone Density
;
Bone Diseases, Metabolic
;
Calcium
;
Community Health Centers
;
Cross-Sectional Studies
;
Female
;
Femur Neck
;
Health Behavior
;
Humans
;
Korea
;
Middle Aged
;
Osteoporosis
;
Self Efficacy
;
Vitamins
2.Immunogenicity and reactogenicity of a yeast recombinant DNA hepatitis B vaccine in healthy subjects.
Kyo Myong KIM ; Sang Eun CHU ; Hae Ran LEE ; Hae Sun YOON ; Kyu Man LEE ; Chang Hong MIN
Journal of the Korean Society for Microbiology 1991;26(6):493-498
No abstract available.
DNA, Recombinant*
;
Hepatitis B Vaccines*
;
Hepatitis B*
;
Hepatitis*
;
Yeasts*
3.Glucose/oxygen deprivation induces release of (3H)5-hydroxytryptamine associated with synapsin 1 expression in rat hippocampal slices.
Eun Mi PARK ; Sang Hui CHU ; Kyung Eun LEE
The Korean Journal of Physiology and Pharmacology 2000;4(5):347-353
It has been well documented that a massive release of not only glutamate but also other neurotransmitters may modulate the final responses of nerve cells to the ischemic neuronal injury. But there is no information regarding whether the release of monoamines is directly associated with synaptic vesicular proteins under ischemia. In the present study, it was investigated whether synapsin 1, syntaxin and SNAP-25 are involved in the release of 5-hydroxytryptamine ((3H)5-HT) in glucose/oxygen deprived (GOD) rat hippocampal slices. And, the effect of NMDA receptor using DL-2-amino-5-phosphonovaleric acid (APV) on ischemia-induced release of 5-HT and the changes of the above proteins were also investigated. GOD for 20 minutes enhanced release of (3H)5-HT, which was in part blocked by the NMDA receptor antagonist, APV. The augmented expression of synapsin 1 during GOD for 20 minutes, which was also in part prevented by APV. In contrast, the expression of syntaxin and SNAP-25 were not altered during GOD. These results suggest that ischemic insult induces release of (3H)5-HT associated with synapsin 1, synaptic vesicular protein, via activation of NMDA receptor in part.
Animals
;
Glutamic Acid
;
Ischemia
;
N-Methylaspartate
;
Neurons
;
Neurotransmitter Agents
;
Qa-SNARE Proteins
;
Rats*
;
Serotonin
4.Antenatal Sonographic Diagnosis of the Amniotic Band Syndrome.
Nak Woon JUNG ; Hye Sung WON ; Hyung Sik CHU ; Sang Soo LEE ; Pyl Ryang LEE ; In Sik LEE ; Ahm KIM ; Jung Eun MOK
Korean Journal of Perinatology 1997;8(3):285-290
The amniotic band syndrome is a collection of fetal malformations caused by fibrous bands that appear to entangle or entrap various parts of fetus in utero, leading to deformation, malformation, or disruption involving the limbs, craniofacial region and trunk. The incidence of this syndrome is relatively rare. This syndrome often shows irreversible serious outcome. So, early diagnosis of amniotic band syndrome is important. Ultrasonography enables us to detect the amniotic band syndrome prenatally. In the second and third trimester of the pregnancy, it is relatively easy to detect major anomalies of amniotic band syndrome by its characteristic features, including amputation and/or constriction of the extremities, facial clefts, asymmetric encephaloceles and gastroschisis. Five cases of amniotic band syndrome which have been diagnosed prenatally by ultrasonography are discussed. The diagnosis was based on sonographic visualization of amniotic band and associated fetal deformation, malformations or disruption known to characterize the amniotic band syndrome.
Amniotic Band Syndrome*
;
Amputation
;
Constriction
;
Diagnosis*
;
Early Diagnosis
;
Encephalocele
;
Extremities
;
Female
;
Fetus
;
Gastroschisis
;
Humans
;
Incidence
;
Infant, Newborn
;
Pregnancy
;
Pregnancy Trimester, Third
;
Ultrasonography*
5.Female College Students' Knowledge, Self-efficacy and Health Behaviors related to Bone Health.
Eui Geum OH ; Il Sun KO ; Sang Hui CHU ; Jung Eun LEE ; Jae Yong YOO
Korean Journal of Women Health Nursing 2012;18(1):38-48
PURPOSE: This study described female college students' knowledge, self-efficacy and health behaviors related to bone health. METHODS: A descriptive cross-sectional survey design was used. A total of 214 students were conveniently recruited from a school of nursing in Korea. Participants (mean age=21.2, SD=1.9 years) bone mineral density (BMD) was measured using dual energy x-ray absorptionmetry. Participants also completed a questionnaire consisting of knowledge test, self-efficacy scale and health behaviors related to bone health. Data were analyzed using SPSS/WIN 17.0 program. RESULTS: The mean BMD at left femoral neck site was 0.86 g/cm2 and 6.1~12.6%. Results showed that participants were below the expected range of BMD. Level of knowledge (correct rate=54%) and self-efficacy were moderate (mean 54.8 out of 84). More than 84% of subjects drank alcohol more than once a month and 58.4% did participate in regular exercise. Only 7.9% participants took calcium and vitamin-D rich foods every day. There were significant positive correlations between knowledge and self-efficacy (r=.17), health behaviors (r=.14) and self-efficacy and health behaviors (r=.28, all p<.05). CONCLUSION: These results suggest that health care professionals need to provide effective interventions for young women in order to enhance knowledge, self-efficacy and health behaviors related to bone health.
Bone Density
;
Calcium
;
Cross-Sectional Studies
;
Delivery of Health Care
;
Female
;
Femur Neck
;
Health Behavior
;
Humans
;
Korea
;
Surveys and Questionnaires
6.The Scene Time Interval and Basic Life Support Termination of Resuscitation Rule in Adult Out-of-Hospital Cardiac Arrest.
Tae Han KIM ; Sang Do SHIN ; Yu Jin KIM ; Chu Hyun KIM ; Jeong Eun KIM
Journal of Korean Medical Science 2015;30(1):104-109
We validated the basic life support termination of resuscitation (BLS TOR) rule retrospectively using Out-of-Hospital Cardiac Arrest (OHCA) data of metropolitan emergency medical service (EMS) in Korea. We also tested it by investigating the scene time interval for supplementing the BLS TOR rule. OHCA database of Seoul (January 2011 to December 2012) was used, which is composed of ambulance data and hospital medical record review. EMS-treated OHCA and 19 yr or older victims were enrolled, after excluding cases occurred in the ambulance and with incomplete information. The primary and secondary outcomes were hospital mortality and poor neurologic outcome. After calculating the sensitivity (SS), specificity (SP), and the positive and negative predictive values (PPV and NPV), tested the rule according to the scene time interval group for sensitivity analysis. Of total 4,835 analyzed patients, 3,361 (69.5%) cases met all 3 criteria of the BLS TOR rule. Of these, 3,224 (95.9%) were dead at discharge (SS,73.5%; SP,69.6%; PPV,95.9%; NPV, 21.3%) and 3,342 (99.4%) showed poor neurologic outcome at discharge (SS, 75.2%; SP, 89.9%; PPV, 99.4%; NPV, 11.5%). The cut-off scene time intervals for 100% SS and PPV were more than 20 min for survival to discharge and more than 14 min for good neurological recovery. The BLS TOR rule showed relatively lower SS and PPV in OHCA data in Seoul, Korea.
Adult
;
Advanced Cardiac Life Support/*mortality
;
Cardiopulmonary Resuscitation/*mortality
;
Critical Care/statistics & numerical data
;
Decision Support Techniques
;
Electric Countershock/*mortality
;
Emergency Medical Services
;
Female
;
Hospital Mortality
;
Humans
;
Male
;
Out-of-Hospital Cardiac Arrest/*epidemiology/*mortality/therapy
;
Refusal to Treat
;
Republic of Korea/epidemiology
;
Retrospective Studies
;
Survival Rate
;
Time Factors
;
Time-to-Treatment
;
Treatment Outcome
7.A Case of Ameloblastic Fibrodentinoma in Nasal Floor.
Sun Ki KIM ; Sang Won YOON ; Jong Eun CHU
Korean Journal of Otolaryngology - Head and Neck Surgery 2008;51(8):755-757
Ameloblastic fibrodentinoma is an extremely rare benign tumor composed of odontogenic epithelium and stroma with dentin. It usually arises in the posterior mandible (maxilla-mandible ratio 1:3) and is commonly associated with the unerupted molar teeth of young adults, adolescents and children. It mainly affects people younger than 4th decades of age and is found more commonly in males than in females. Ameloblastic fibrodentinoma usually grows slowly without any symptoms, but sometimes it may grow rapidly. Radiographically, it shows well-delineated radiolucency, but it may be seen as a radiopaque mass in its mature stage. Ameloblastic fibrodentinoma of nasal floor is an extremely rare entity and no document in the literature was found. Recently, we experienced a case of ameloblastic fibrodentinoma of nasal floor which was confirmed by excisional biopsy. Thus, for the first time in Korea, we report a case of ameloblastic fibrodentinoma of the nasal floor with a review of literature.
Adolescent
;
Ameloblasts
;
Biopsy
;
Child
;
Dentin
;
Epithelium
;
Female
;
Floors and Floorcoverings
;
Humans
;
Korea
;
Male
;
Mandible
;
Molar
;
Nasal Cavity
;
Odontogenic Tumors
;
Tooth
;
Young Adult
8.Glycochenodeoxycholic acid induces cell death in primary cultured rat hepatocyte: Apoptosis and necrosis.
Sang Hui CHU ; Wol Mi PARK ; Kyung Eun LEE ; Young Sook PAE
The Korean Journal of Physiology and Pharmacology 1999;3(6):565-570
Intracellular accumulation of bile acids in the hepatocytes during cholestasis is thought to be pathogenic in cholestatic liver injury. Due to the detergent-like effect of the hydrophobic bile acids, hepatocellular injury has been attributed to direct membrane damage. However histological findings of cholestatic liver diseases suggest apoptosis can be a mechanism of cell death during cholestatic liver diseases instead of necrosis. To determine the pattern of hepatocellular toxicity induced by bile acid, we incubated primary cultured rat hepatocytes with a hydrophobic bile acid, Glycochenodeoxycholate (GCDC), up to 5 hours. After 5 hours incubation with 400 muM GCDC, lactate dehydrogenase released significantly. Cell viability, quantitated in propidium iodide stained cells concomitant with fluoresceindiacetate was decreased time-and dose-dependently. Most nuclei with condensed chromatin and shrunk cytoplasm were heavily labelled time- and dose-dependently by a positive TUNEL reaction. These findings suggest that both apoptosis and necrosis are involved in hepatocytes injury caused by GCDC.
Animals
;
Apoptosis*
;
Bile
;
Bile Acids and Salts
;
Cell Death*
;
Cell Survival
;
Cholestasis
;
Chromatin
;
Cytoplasm
;
Glycochenodeoxycholic Acid*
;
Hepatocytes*
;
In Situ Nick-End Labeling
;
L-Lactate Dehydrogenase
;
Liver
;
Liver Diseases
;
Membranes
;
Necrosis*
;
Propidium
;
Rats*
9.Snoring as a Risk Factor of Fall in the Community Elderly.
Juho PARK ; Woo Jung KIM ; Yoosik YOUM ; Hyeon Chang KIM ; Yeong Ran PARK ; Sang Hui CHU ; Kee NAMKOONG ; Eun LEE
Journal of Korean Geriatric Psychiatry 2018;22(1):7-12
OBJECTIVE: Fall is one of major causes of morbidity and mortality in the elderly. It is known that sleep is associated with quality of life in the elderly. Snoring is one of the factors affecting sleep quality. The aim of the study was to examine whether snoring affect fall in the community elderly. METHODS: This survey was performed as a part of the Korean Social Life, Health, and Aging Project, which studied the elderly living in Ganghwa-gun. Fall was defined as any history of fall in the last year through face-to-face interview. We examined the following variables: age, sex, snoring, insomnia, hypertension, diabetes, stroke, bone disease, vision problems, depression, alcohol intake, mini-mental state examination, and body mass index. The data was analyzed by multiple logistic regression to determine the association of fall with the risk factors. RESULTS: In the multivariate analysis of 516 participants, the adjusted odd ratios (95% confidence interval) of simple snoring affecting fall was 1.70 (1.10–2.63). In addition, sex (female), age, and diabetes were significantly predicted the fall. CONCLUSION: Our result suggested that snoring could be a risk factor of fall. A more comprehensive study of the relationship between snoring and fall is needed to improve the quality of life of the community elderly.
Aged*
;
Aging
;
Body Mass Index
;
Bone Diseases
;
Depression
;
Humans
;
Hypertension
;
Logistic Models
;
Mortality
;
Multivariate Analysis
;
Quality of Life
;
Risk Factors*
;
Sleep Initiation and Maintenance Disorders
;
Snoring*
;
Stroke
10.A Case Report of Human Thelaziasis.
Yoo Jung CHO ; Jong Phil CHU ; Eun Ju KIM ; Moo Sang KIM ; Woo Ho NAM ; Kyung Hyun JIN
Infection and Chemotherapy 2006;38(2):104-107
The authors report a case of infection with Thelazia callipaeda in a Korean man. The patient was a 47 year-old man. He experienced epiphora and foreign body sensation of the right eye since 3 weeks ago. Total of 2 worms were removed from the conjunctival sac; one by himself 1 day prior to examination and the other by an ophthalmologist. The worm was slender creamy white in color which was fixed in a 10% formaline solution. The worm was 17.38 mm in length, 0.45 mm in body width, 0.026 mm in length of buccal cavity, 0.63 mm in length of anterior end to vaginal opening, 0.76 mm in length of anterior end to the esophagointestinal junction and 0.06 mm in length of posterior end to the anus. There were numerous striations on surface of worms and vaginal opening was located anterior to the esophagointestinal junction. Based on aforementioned findings, it was confirmed as a female worm of Thelazia callipaeda, and the authors report it with literature.
Anal Canal
;
Female
;
Foreign Bodies
;
Formaldehyde
;
Humans*
;
Lacrimal Apparatus Diseases
;
Middle Aged
;
Sensation
;
Thelazioidea