1.A Study on the Maternal and Child Health Status in a Rural Area.
Korean Journal of Preventive Medicine 1974;7(2):333-342
No abstract available.
Child
;
Child Health*
;
Child*
;
Humans
2.A Case of Remitted Lambert-Eaton Myasthenic Syndrome with Small Cell Lung Carcinoma Following Chemotherapy and Radiotherapy.
Sang Ahm LEE ; Il Nam SUNWOO ; Jae Kyoung RO ; Kee Duk PARK
Journal of the Korean Neurological Association 1992;10(3):401-406
In one case of cancer-associated Lambert-Eaton myasthenic syndrome (LEMS), treatment with cytotoxic chemotherapy and radiotherapy resulted in remission of both cancer and neuromuscular disorder. Serial repetitive nerve stimulation (RNS) findings showed that the typical RNS features of LEMS returned to normal in the orders of dramatic postexercise facilitation, an incremental response in high rate stimulation, and a decremental response in low rate stimulation with clinical improvement.
Drug Therapy*
;
Lambert-Eaton Myasthenic Syndrome*
;
Radiotherapy*
;
Small Cell Lung Carcinoma*
3.Clinical Result of Excimer Laser Photoastigmatic Refractive Keratectomy Using VISX 20/20 B VisionKeyTM with Version 4.01 Software.
Sang Bumm LEE ; Nam Gyu PARK ; Duk Kee HAHN
Journal of the Korean Ophthalmological Society 1998;39(2):255-269
Photoastigmatic refractive keratectomy (PARK) using VISX 20/20 B excimer laser with version 4.01 software was performed in 205 consecutive eyes of compound myopic astigmatism to assess the efficacy, predictability, and safety of excimer laser treatment of compound myopic astigmatism between September 1994 and June 1996. The mean preoperative manifest spherical equivalent refraction was -6.95+/-2.52D (range -1.13 to -15D) and the mean preoperative manifest cylindrical refraction was -1.25+/-0.76D (range -0.5 to -4.50D). The patients were followed from 6 months to 1 year (mean 9.19 months). At 1 year, 82(75.2%) of all 109 eyes receiving PARK were within 1D of plano refraction, and 88(80.7%) of all 109 eyes achieved uncorrected visual acuity of 20/30 or better. Postoperative refractions were stable after 3 months without significant early overcorrection. Mean postoperative astigmatism was -0.29+/-0.40D at 6 months and -0.24+/-0.42D at 12 months. Overall improvement of astigmatism was 75% at 6 months and 82% at 12 months by vector analysis using Alpins` method. In conclusion, PARK using VISX 20/20 B VisionKeyTM excimer laser with version 4.01 software appears to be effective in the treatment of compound myopic astigmatism with a relatively high degree of accuracy and safety. The predictability and stability of the postoperative refraction during the first 12 months seem to be quite reliable.
Astigmatism
;
Humans
;
Lasers, Excimer*
;
Visual Acuity
4.Clinical Predictors of Novel Influenza A (H1N1) Infection in Korea.
Choon Ok KIM ; Chung Mo NAM ; Duk Chul LEE ; Sang Hoon HAN ; Ji Won LEE
Yonsei Medical Journal 2010;51(6):895-900
PURPOSE: Pandemic influenza A (H1N1) virus has spread rapidly and prompt diagnosis is needed for successful treatment and prevention of transmission. We investigated clinical predictors, validated the use of previous criteria with laboratory tests, and evaluated the clinical criteria for H1N1 infection in the Korean population. MATERIALS AND METHODS: We analyzed clinical and laboratory evaluation data from outpatient clinics at Severance Hospital in Seoul, Korea between November 11 and December 5, 2009. RESULTS: This analysis included a total of 828 patients. Of these, 372 (44.9%) patients were confirmed with H1N1 infection by real-time reverse transcriptase-polymerase chain reaction (RT-PCR). The most common and predictive symptom was cough (90.3%, OR 8.87, 95% CI 5.89-13.38) and about 40% of H1N1-positive patients were afebrile. The best predictive model of H1N1 infection was cough plus fever or myalgia. The sensitivities, specificities, positive predictive values, and negative predictive values of our suggested criteria were 73.9%, 69.5%, 66.4%, and 76.6%, respectively. CONCLUSION: Cough was the most common independent symptom in patients with laboratory-confirmed H1N1 infection, and while not perfect, the combination of cough plus fever or myalgia is suggested as clinical diagnostic criteria. Health care providers in Korea should suspect a cough without fever to be an early symptom of H1N1 infection.
Adolescent
;
Adult
;
Aged
;
Aged, 80 and over
;
Female
;
Humans
;
Influenza A Virus, H1N1 Subtype/*metabolism
;
Influenza, Human/*diagnosis/*epidemiology/virology
;
Male
;
Middle Aged
;
Pandemics
;
Predictive Value of Tests
;
Republic of Korea
;
Reverse Transcriptase Polymerase Chain Reaction
;
Sensitivity and Specificity
5.Pheochromocytoma in pregnancy: A case report.
Jae Hyun CHO ; Sang Woon PARK ; Kyung Duk LEE ; Young Jung CHO ; Hong Woo NAM
Korean Journal of Medicine 2005;68(3):325-328
Pheochromocytoma during pregnancy is very rarely discovered, and this condition is life threatening to both mother and fetus. Maternal and fetal survival depend a lot on an early diagnosis, a correct medical therapy and a correct timing of delivery and surgery. We describe a case of pheochromocytoma during pregnancy. A patient was transferred to our hospital during gestational week 24 with severe hypertension, generalized edema. Pheochromocytoma caused by a left adrenal mass was diagnosed. The patient was treated with titrated dose of phenoxybenzamine, propranolol, and intravenous nicardipine, but intermittent severe hypertension was developed. At 33 weeks gestation, fetal distress was developed, and emergent cesarean section was done. Two weeks after delivery, she underwent a successful left adrenalectomy. Two months after surgery, all antihypertensive medications were discontinued and her blood pressure have remained normal range.
Adrenalectomy
;
Blood Pressure
;
Cesarean Section
;
Early Diagnosis
;
Edema
;
Female
;
Fetal Distress
;
Fetus
;
Humans
;
Hypertension
;
Mothers
;
Nicardipine
;
Phenoxybenzamine
;
Pheochromocytoma*
;
Pregnancy*
;
Propranolol
;
Reference Values
6.Extrusion of Gutta-Percha into the Nasal Cavity Causing Maxillary Fungal Sinusitis: A Case Report.
Myung Eun NAM ; Sang Duk HONG ; Jun Oh PARK ; Seung Kyu CHUNG
Journal of Rhinology 2013;20(2):127-129
There have been few reports about extrusion of endodontic obturation materials into the maxillary sinus and inducing fungal sinusitis. Endodontic materials and fungus balls both are seen as high attenuation in a CT scan so may be overlooked. We report such a case in which the surgeon and radiologist had missed the foreign materials on preoperative CT scans, and recognized the filling defect on the alveolar bone and a foreign body in the nasal cavity postoperatively.
Foreign Bodies
;
Fungi
;
Gutta-Percha*
;
Maxillary Sinus
;
Nasal Cavity*
;
Sinusitis*
;
Tomography, X-Ray Computed
7.Extrusion of Gutta-Percha into the Nasal Cavity Causing Maxillary Fungal Sinusitis: A Case Report.
Myung Eun NAM ; Sang Duk HONG ; Jun Oh PARK ; Seung Kyu CHUNG
Journal of Rhinology 2013;20(2):127-129
There have been few reports about extrusion of endodontic obturation materials into the maxillary sinus and inducing fungal sinusitis. Endodontic materials and fungus balls both are seen as high attenuation in a CT scan so may be overlooked. We report such a case in which the surgeon and radiologist had missed the foreign materials on preoperative CT scans, and recognized the filling defect on the alveolar bone and a foreign body in the nasal cavity postoperatively.
Foreign Bodies
;
Fungi
;
Gutta-Percha*
;
Maxillary Sinus
;
Nasal Cavity*
;
Sinusitis*
;
Tomography, X-Ray Computed
8.The Prevalence of Maturity Onset Diabetes of the Young(MODY) 3 in Children with Type 2 Diabetes Mellitus.
In Kyoung CHOI ; Duk Hee KIM ; Ho Seong KIM ; Nam HUH ; Sang Hyun PAEK ; Seoung Young JUNG
Korean Journal of Pediatrics 2004;47(6):641-646
PURPOSE: Maturity-onset diabetes of the young(MODY) is a subtype of type 2 diabetes defined by autosomal dominant mode of inheritance, onset of diabetes usually before the age of 25 yrs, and a primary defect in the function of the beta cells of the pancreas. MODY3 is known as the most common form and is caused by mutations in hepatocyte nuclear factor(HNF)-1alpha. We examined the prevalence of MODY3 in children with type 2 diabetes mellitus(DM). METHODS: Children with type 2 DM(N=17) and their family members with type 2 DM(N=5) were enrolled. Inclusion criteria for the children were fasting C-peptide and postprandial C-peptide more than 1.0 ng/mL and 1.5 ng/mL respectively, familial type 2 DM in at least two generations, and body mass index(BMI)(kg/m(2)) less than 95th percentile. Genomic DNA was extracted from blood samples. We analyzed HNF-1alpha for mutation by DNA microarray method and direct sequencing. RESULTS: We found one case with a mutation of the promoter region of HNF-1alpha(5'-ctaGGCTAGTGGGGTTTTGCGGGGGCAGTGGGTGCAAGG-3') in one child's family member among 22 children and adult subjects with type 2 DM. CONCLUSION: Although we found a mutation of HNF-1alpha in an adult family member with type 2 DM, we did not find this mutation in a child with type 2 DM. The further investigation of MODY in children, including other types, is required.
Adult
;
C-Peptide
;
Child*
;
Diabetes Mellitus, Type 2*
;
DNA
;
Family Characteristics
;
Fasting
;
Hepatocyte Nuclear Factor 1-alpha
;
Hepatocytes
;
Humans
;
Oligonucleotide Array Sequence Analysis
;
Pancreas
;
Prevalence*
;
Promoter Regions, Genetic
;
Wills
9.Cliaical Characteristics of Benign Focal Amyotrophy.
Keun Ho CHEONG ; Phil Za CHO ; Il Nam SUNWOO ; Young Kwan PARK ; Sang Ahm LEE ; Ki Whan KIM ; Kee Duk PARK
Journal of the Korean Neurological Association 1992;10(4):447-456
A discription is given of 24 patients with the benigen focal amyotrophy; Nineteen had upper-limb and five had lower-limb involvement. The characteristic clinca! Features were insidious onset in the second and third decades, male predominance. Sporadic occurance, wasting and weakness confined to one limb, relatively good prognosis and absence of involvement of the cranial nerves, cerebrum, brainstem, and sensory syetem. The nerve conduction studies, electromyographic pattems, somatosensory evoked potential studies, and CTMM or MR findings suggested anterior horn cell disorders. In nine cases we were able to demonstrate focal atrophy in the lower cervical cord limited to the ipsilateral anterior horn region, and two cases segmental cord atrophy in the lower cervical cord in MR or CTMM studies. The benign focal amyotrophy, for which no causes been described, is benign and self-limiting, unlike most motor neuron diseases.
Animals
;
Anterior Horn Cells
;
Atrophy
;
Brain Stem
;
Cerebrum
;
Cranial Nerves
;
Evoked Potentials, Somatosensory
;
Extremities
;
Horns
;
Humans
;
Male
;
Motor Neuron Disease
;
Neural Conduction
;
Prognosis
10.Cliaical Characteristics of Benign Focal Amyotrophy.
Keun Ho CHEONG ; Phil Za CHO ; Il Nam SUNWOO ; Young Kwan PARK ; Sang Ahm LEE ; Ki Whan KIM ; Kee Duk PARK
Journal of the Korean Neurological Association 1992;10(4):447-456
A discription is given of 24 patients with the benigen focal amyotrophy; Nineteen had upper-limb and five had lower-limb involvement. The characteristic clinca! Features were insidious onset in the second and third decades, male predominance. Sporadic occurance, wasting and weakness confined to one limb, relatively good prognosis and absence of involvement of the cranial nerves, cerebrum, brainstem, and sensory syetem. The nerve conduction studies, electromyographic pattems, somatosensory evoked potential studies, and CTMM or MR findings suggested anterior horn cell disorders. In nine cases we were able to demonstrate focal atrophy in the lower cervical cord limited to the ipsilateral anterior horn region, and two cases segmental cord atrophy in the lower cervical cord in MR or CTMM studies. The benign focal amyotrophy, for which no causes been described, is benign and self-limiting, unlike most motor neuron diseases.
Animals
;
Anterior Horn Cells
;
Atrophy
;
Brain Stem
;
Cerebrum
;
Cranial Nerves
;
Evoked Potentials, Somatosensory
;
Extremities
;
Horns
;
Humans
;
Male
;
Motor Neuron Disease
;
Neural Conduction
;
Prognosis