1.Therapeutic Equivalence and Bioequivalence.
Sang Goo SHIN ; Dong Ryul SOHN
Journal of the Korean Medical Association 1999;42(8):775-780
No abstract available.
Therapeutic Equivalency*
3.A Case of Lichen Nitidus Coexisted with Molluscum Contagiosum.
Deok Yong SHIN ; Sang Dong KIM ; Dae Won KOO
Korean Journal of Dermatology 1999;37(1):125-127
Lichen nitidus is an uncommon chronic dermatosis characterized by its typical clinical and histopathologic findings and has rarely been described in association with other diseases. We observed a patient with an association of lichen nitidus and molluscum contagiosum, which to the best of our knowledge has not been previously reported in the literature. It remains to be further studied about a possible pathogenesis of lichen nitidus secondary to some viral infections such as molluscum contagiosum, etc.
Humans
;
Lichen Nitidus*
;
Lichens*
;
Molluscum Contagiosum*
;
Skin Diseases
4.The Study of Sweat and Serum Carcinoembryonic Antigen Values in Healthy Subjects.
Ho Cheol SHIN ; Sang Won KIM ; Dong Seok KIM
Korean Journal of Dermatology 1994;32(6):1005-1010
BACKGROUND: The positive reactions of carcinoembryonic antigen(CEA) show varying degrees in the tissue of all sweat gland neoplasms by immunohistochemistry. The CEA secreted from sweat glands presents a high value, compared with that of serum. OBJECTIVE: The study was to evaluate the sweat CEA value in relation to serum CEA value by sex, smoking status and blood type in healthy subjects. METHOD: Fifty-two healthy subjects(M : 43, F :9) aged 21-30, participated in the study. 2ml sweat was collected from the face and chest after intense exercises and 3ml blood was collected from their antecubital veins. Roche Core CEA enzyme immunoassay was used for the measurement of sweat and serum CEA. RESULTS: Sweat CEA values were 102.0+4100.5ng/ml in males and 70.6+458.5ng/ml in females, with their mean valueof 96.6+/-94.9ng/ml. Sweat CEA values were 108.3+/-103.5ng/ml in 27 smokers and 83.9+/-84.8ng/ml in 25 nonsmokers(p>0.05, t-test). Sweat CEA values were higher among the males and the smokers. Serum CEA values were 2.5+/-1.7ng/ml in males and 1.6+/-0.8ng/ml in females, with its mean value of 2.4+/-1.6ng/ml. There was no difference between serum values of smokers and nonsmokers. Sweat CEA values were about 40 times higher than those of serum, with no correlation of sweat and serum CEA(correlation coefficient=-0.16, P>0.05). In the blood type study, sweat CEA values were 123.1+/-131.8ng/ml in A type and 66.1+/-55.0ng/ml in B type(P>0.05), whereas serum CEA values were higher in AB type and lower in O type(P<0.05, ANOVA). CONCLUSION: Sweat CEA values are extraordinarily high in contradistinction to serum. Sweat CEA values are not affected by sex, smoking status and blood type. There seems to be no association between CEA values of sweat and serum.
Carcinoembryonic Antigen*
;
Exercise
;
Female
;
Humans
;
Immunoenzyme Techniques
;
Immunohistochemistry
;
Male
;
Smoke
;
Smoking
;
Sweat Gland Neoplasms
;
Sweat Glands
;
Sweat*
;
Thorax
;
Veins
5.Diagnostic peritoneal larvage versus computerized axial tomgraphy in evaluating the abdominal trauma.
Hoi Dong GHU ; Sang Young CHUNG ; Shin Kon KIM
Journal of the Korean Surgical Society 1993;44(4):490-496
No abstract available.
6.The Effects of Doxapram on the Pulmonary Function during Total Intravenous Anesthesia with Propofol According to Nalbuphine Pretreatment.
Sang Wook SHIN ; Dong Hee KANG ; Seung Wan BAIK
Korean Journal of Anesthesiology 1997;33(5):883-889
BACKGROUND: Total intravenous anesthesia with propofol can cause respiratory depression and apnea especially during induction of anesthesia. To study the possibility of reversal of respiratory depression during anesthesia with propofol, pretreated with nabuphine or not, the respiratory effects of doxapram to spontaneously ventilating patients were investigated. METHODS: Patients were divided into 4 groups - saline-propofol-saline group (SPS), saline-propofol- doxapram group (SPD), nalbuphine-propofol-saline group (NPS), and nalbuphine-propofol-doxapram group (NPD). After saline or nalbuphine pretreatment, anesthesia was induced with propofol and then doxapram or saline was intravenously injected. Apneic time interval, blood pressure, heart rate, respiratory rate, minute ventilation, end tidal CO2 partial pressure and oxygen saturation were measured in every minutes during induction of anesthesia. Percent changes of each values were compared. RESULTS: There is no differences in apneic time intervals in each groups. The percent change of first minute ventilation in SPD group after doxapram injection unchanged significantly compared with those depressions of SPS, NPS and NPD group (p<0.05). Respiratory rates increased in SPD and SPS groups after laryngeal mask insertion. There is no differences in minute ventilation, respiratory rate and end-tidal CO2 concentration between nalbuphine pretreated groups regardless of doxapram injection. CONCLUSIONS: Doxapram has effect in increasing minute ventilation after propofol induction within first few minutes, but it cannot reverse respiratory depression during propofol induction pretreated with nalbuphine.
Anesthesia
;
Anesthesia, Intravenous*
;
Apnea
;
Blood Pressure
;
Depression
;
Doxapram*
;
Heart Rate
;
Humans
;
Laryngeal Masks
;
Nalbuphine*
;
Oxygen
;
Partial Pressure
;
Propofol*
;
Respiratory Insufficiency
;
Respiratory Rate
;
Ventilation
7.Intraoperative Technical Errors and Postoperative Complications of Bone Patellar Tendon Bone ACL Recostruction.
Dong Min SHIN ; Jun Young LEE ; Sang Ho HA
Journal of the Korean Knee Society 1997;9(2):168-172
The most commonly used graft source for anterior cruciate ligament reconstruction is the autogenous bone- patellar tendon-bone graft unit. Despite a good success record, intraoperative technical errors and postoperative complications have been known. Author analyzed intraoperative technical errors and postoperative complications, in 44 patients who were treated at the department of orthopaedic surgery, chosun university hospital from Jan. 1994 to Jun. 1996. The most common intraoperative technical errors was screw graft divergency in 5 cases. Other intraoperative technical errors were too anteriorly location of femoral tunnel in 1 case, too anteriorly location of tibial k femora) tunne.l both in 1 case, graft tunnel mismatching in 1 case, graft pullout in 1 case and partial destruction of posterior cortex of femoral tunnel in 1 case, fracture of the bone plug in 1 case. The most common postoperative complication was patellar tendinitis in 20 cases (45.5%). Other postoperative complications were anterior knee pain in 14 case. (31.8%), patellar crepitation in 12 cases (27.3%), quadriceps atrophy in 9 cases (20.5%), arthrofibrosis in 3 cases and graft failure in 2 cases. Author concluded the causes of intraoperative complications were technical errors, and anteriorly location of graft tunnel is most influenced factor to final fuctional results. To eliminate the postoperative complications, intraoperative technical errors should be avoided and also accelerated rehabilitation should be done.
Anterior Cruciate Ligament Reconstruction
;
Atrophy
;
Humans
;
Intraoperative Complications
;
Knee
;
Patellar Ligament*
;
Postoperative Complications*
;
Rehabilitation
;
Tendinopathy
;
Transplants
8.Comparative Analysis for the Patellar Bony Defect Using by Autogenous Bone: Patellar Tendon - Bone ACL Reconstruction - Donor Site Morbidity & Morphological Change Between the Group of Non - replaced Bony Defect and the Group of Replaced Bony Defect Using.
Dong Min SHIN ; Sang Ho HA ; Hong Moon SOHN
Journal of the Korean Knee Society 1997;9(1):19-22
Arthroscopic anterior cruciate ligament reconstruction with bone-patella tendon-bone has been commonly using for ACL insufficient patients. Bone-patellar tendon-bone graft is a strong intra-articular substitute, which allows, by means of its bony end, a rigid fixation with early bone to hone healing. As a counterpart, potentially serious cornplications & donor site morbidity has been reported, such as patella fracture & patella tendon avulsion, anterior knee pain, patella tendinitis, dcmor site pain and bone defect. We suppose tightly packing the donor site bony defect with hetrograft (Lubboc) may be also useful. So, we analyzed the morphological change in bony defect and donor site morbidity between the group of non-replaced bony defect and the group of replaced bony defect using by heterograft (Lubboc). We replaceJ hetrograft into the patellar side bony defect in 15 knees and left alone in l5 knees. The average follow up period was 17 months. The results werc as follows: 1. Nearly norma1 appearance on the bony defect showed at the long tenn follow up roentgenogram in the group of replaced hetrograft, but scalloping on the pateltar bomp defect was seen in non-replaced group. 2. Donor site morbidity (pain or patellai tendinitis) was developed 8 knees in the replaced group, and 7 knees in the non-rep)aced group. 3. We conclude that the filled in the bony defect hy hone graft (heterografl:) can not decrease the donor site morbidi ty.
Anterior Cruciate Ligament Reconstruction
;
Bone-Patellar Tendon-Bone Grafts
;
Follow-Up Studies
;
Heterografts*
;
Humans
;
Knee
;
Patella
;
Patellar Ligament*
;
Pectinidae
;
Tendinopathy
;
Tissue Donors*
;
Transplants
9.Treatment of the type III fractures of the intercondylar eminence of the tibia.
Dong Min SHIN ; Sang Ho HA ; Min HEO
The Journal of the Korean Orthopaedic Association 1993;28(6):2103-2110
No abstract available.
Tibia*
10.Isolated avulsion fracture of the tibial attachment of the posterior cruciate ligament.
Dong Min SHIN ; Sang Ho HA ; Byoung Kwan AHN
The Journal of the Korean Orthopaedic Association 1992;27(7):1738-1744
No abstract available.
Posterior Cruciate Ligament*