The adult worms of cestodes, Moniezia expansa and Diphyllobothrium mansoni employed in this experiment. The worms were divided into three portions, i.e. immature , mature and gravid proglottids, and each proglottids were incubated in a certain incubation period, and the glucose uptake rate, total CO2 production rate, tissue concentration and their radioactivities were employed as previous reports(Rim et al., 1965). The glucose uptake rate by M. expansa was a mean value of 6.46+/-1.23 micromole per hour per gram of wet wt. and the rate by D. mansoni was a mean value of 18.8+/-0.8 micro-mole per hour per gram of wet wt. The higher rates were observed in the mature proglottid of M. expansa and in the immature proglottid of D. mansoni . The total CO(2) production rates by the worms averaged 14.0+/-2.37 micro-mole per hour per gram in M. expansa and 17.51+/-1.54 micro-mole per hour per gram of wet wt. The relative specific activities of respiratory CO(2)(R.S.A CO(2)) averaged 22.2+/-5.15 percent in M. expansa and 54.2+/-2.2 per cent in D. mansoni. In the both worms, the higher values were obtained in the mature proglottids. Therefore, the average value of 8.84+/-2.66 per cent of glucose utilized by M. expansa and 8.23+/-0.50 percent of glucose utilized by D. mansoni from the medium glucose was oxidized into respiratory CO(2). The tissue concentrations of glycogen were a mean of 2.21+/-0.46 percent per gram of wet wt. in M. expansa and 7.56+/-1.24 percent per gram of wet wt. in D. mansoni. The higher concentration of glycogen was observed in the gravid proglottids of M. expansa, however the gravid proglottids of D. mansoni showed lower concentration of glycogen than the other proglottids. The turnover rate of glycogen pool yielded with a mean of 0.04+/-0.01 miligram per hour per gram of wet wt. of M. expansa, whereas a mean of 1.66+/- 0.46 miligram per hour per gram wet wt. of D. mansoni. Therefore, a mean value of 2.58+/-0.93 per cent(R.G.D gly) of glucose utilized by M. expansa and 53.6+/-1.4 percent by D. mansoni was incorproated into the glycogen . These data account for that at least 11.42 per cent of the utilized glucose by M. expansa and 61.83 per cent of the utilized glucose by D. mansoni participated in furnishing the oxidation into respiratory CO2 and the synthetic process into glycogen.
parasitology ; helminth ; Moniezia expansa ; Diphyllobothrium mansoni ; metabolism ; glucose ; glycogen ; CO(2) ; biochemistry

A clinical observation was made on 143 cases of Intrascrotally impalpable testis seen in Department of Urology, Han Yang University Hospital during the period from May, 1972 to June, 1983. The following results were obtained. 1. Patient`s ranged in age from 10 months to 42 yrs. age. and only 33 cases (23.1%) visited our hospital under 4 yrs. age. 2. 105 cases(75.3%)had unil. involvement & right side was more frequently affected. Bilaterality was noted 34 cases(23.7%). 3. Among 177 exploration, most popular type was prepubic in 71 testes(40.1%) and also 4 cases of anarchism & vanished testis were noted. 4. Chromosomal study was done on 4 cases and all cases yielded 46XY, cytogenetically normal man. 5. Inguinal hernia sac was found in 151 cases(87.2%). 6. Semen analysis was performed on 7 post-pubertal cases and all 3 cases of bil. intrascrotally impalpable testis revealed azoospermia. 7. Pathologic findings of 13 cases were evaluated on the basis of presence of spermatogonia, spermatogenic activity, atrophy of seminiferous tubules, interstitial fibrosis, thickening of B. M. 8. Orchiopexy was performed on 166 cases(93.7%), orchiectomy on 7 cases(4%) and open & closure on 4 cases(2.3%). 9. 2 cases of wound infection & 1 case of testicular atrophy with necrosis was noted.
Atrophy ; Azoospermia ; Fibrosis ; Hernia, Inguinal ; Necrosis ; Orchiectomy ; Orchiopexy ; Semen Analysis ; Seminiferous Tubules ; Spermatogonia ; Testis* ; Urology ; Wound Infection

BACKGROUND: The severity of several chronic inflammatory diseases was reported to be associated with polymorphism of the IL-1 receptor antagonist gene(IL-lrn). OBJECTIVE: This study was performed to study the polymorphism of the IL-1rn in vitiligo and in the normal Korean population. METHODS: Thirty one cases of vitiligo and seventy nine normal Koreans as control were studied for the polymorphism of IL-1 rn. RESULTS: The frequency of allele 2 of the IL- I rn in 31 patients with vitiligo was compared with that of the 79 healthy controls. The frequency of allele 2 was 1.6% in vitiligo patients and 3.8% in the normal controls. CONCLUSION: There was no significant difference in the frequency of allele 2 between the vitiligo patients and normal controls.
Alleles ; Humans ; Interleukin-1* ; Vitiligo*

We report a 72-year-old female patient with spontaneous rupture of the left external iliac vein. She visited our hospital for abdominal and back pain. She had the abnormal finding of hemoperitoneum. We performed an emergency operation with diagnosis of left ovarian cyst rupture though she suffered from spontaneous rupture of the left external iliac vein. This case provides insight to the experience of spontaneous rupture of the left external iliac vein.
Aged ; Back Pain ; Emergencies ; Female ; Hemoperitoneum ; Humans ; Iliac Vein ; Ovarian Cysts ; Rupture ; Rupture, Spontaneous

Of the bronchographic findings of 408 patients, performed in our hospital for recent 5 years, 108 cases showed definite bronchial obstruction, and 61 cases of those were selected and their obstructive findings were evaluated. All that not confirmed were abandoned. For evaluation of the reliability of 9 bronchographic obstruction signs onappplying to diagnose malignant or benign pulmonary diseases, each sign was identified and applied to each of the61 confirmed cases. In addition, obstructed bronchi, distance of obstruction from the bifurcation site, and thedirection of meniscus, if peresent, were evaluated. The reuslts were follows; 1. The most frequent cause ofbronchial obstruction was lung cancer (59.0%), and that of the benign obstruction was pulmonary tuberculosis(13.1%). 2. Amputation, asymmetric narrowing, thumbprint indentation, rat-tail narrowing and encasement signs werethe most accurate signs of malignancy and were practically diagnostic ones, 3, The most frequent sign in lungcancer was sharp cut off one, but it could be seen in lung abscess and in unresolved pneumonia, too. 4. Circumferential symmetric narrowing and regular concavity with a small central profection signs were specific onesto benignancy. 5. The most frequent obstruction sign in benign lung disease was gradual tapering sign, but it alsocould be seen inbronchogenic epidermoid and alveolar cell carcinoma. 6. Of all bronchial obstructions, 55.4% occurred at lobar bronchus and 77.4% of those were caused by lung cancer. 7. 77.2% of those obstruction which located within 3 times distance of the bronchial diameter at the nearest proximal bifurcation site, were lungcancer, but 75.0% of those located at over 3 times distance were benign pulmonary diseases. 8. There were nocorrelation of the direction of the meniscus at the obstructing and in differential diagnosis between benign andmalignant pulmonary diseases.
Adenocarcinoma, Bronchiolo-Alveolar ; Amputation ; Bronchi ; Bronchography ; Diagnosis, Differential ; Humans ; Lung Abscess ; Lung Diseases ; Lung Neoplasms ; Pneumonia

The incidence of primary lung cancer is increasing in our country. This presentation is an attempt to correlate a useful diagnosis with radiological findings of primary lung cancer. Histologically proved 210 cases of primary lung cancer are as follow: Epidermoid Ca. 65%, Adeno Ca. 18%, Small cell Ca. 9.5%, Large cell Ca. 2%, Unclassified Ca. 3.3%, Mucoepidermoid Ca. 2.4%, Mixed Ca. 0.5%. 3. In smoking history; 91% of epidermoid Ca, 17%of small cell Ca. 30% of adeno Ca. has smoking history. 4. In mass size; Average diameter of mass was most was5.3cm. Hilar mass was seen in 48 cases. Hilar mass was most frequent finding in small cell Ca. and the peripheral mass in adeno Ca. 5. Cavitary lung Ca. was 26 cases (12.4%) and most cases had relative thick wall and its mean thickness was 3.6mm. 6. Coexistence of pulmonary tuberculosis and lung cancer was 22 cases (10.5%), and most common in epidermoid cell Ca. as 16 cases. 7. Other findings include metastasis to lymph node, bone and other organ, and pleural effusion.
Diagnosis ; Incidence ; Lung Neoplasms ; Lung ; Lymph Nodes ; Neoplasm Metastasis ; Pleural Effusion ; Smoke ; Smoking ; Tuberculosis, Pulmonary

The glucose uptake rate by plerocercoid of Diphyllobothrium sp. was a mean value of 5.35+/-0.80 micro-mole/hr/g of wet wt, and total CO(2) production rates by the plerocercoid larva averaged 7.54+/-0.73 micro-mole/hr/g of wet wt. The relative specific activity into respiratory CO(2) showed a mean value of 7.30 +/-0.90 per cent. The rate of CO(2) production derived from medium C(14)-glucose was a mean of 0.58+/-0.13 micro-mole/hr/g of wet wt. Therefore, the average value of 1.92+/-0.38 per cent of glucose utilized by the larvae from the medium C(14)-glucose was oxidized to respiratory CO(2). The tissue concentration of glycogen in plerocercoid larva was a mean of 46.28 +/-2.23 mg/g or 4.63+/-0.22 per cent/g of wet wt., and the turnover rate of glycogen pool was a mean of 0.049 +/- 0.012 %/hr or 0.010 +/- 0.003 mg/hr/g of wet wt. The average value of 2.76+/-1.00 per cent of glucose utilized by the larvae from the medium C(14)-glucose was incorporated to the glycogen. These data accounts for that only 5 per cent of the utilized glucose by the plerocercoid larvae participated in furnishing the oxidation into respiratory CO(2) and the synthetic process into glycogen.
parasitology-helminth-cestoda ; Diphyllobothrium sp. ; sparganum ; plerocercoid ; biochemistry ; autoradiography ; glucose ; metabolism ; CO(2)

The use of CT is most reliable in diagnosis and management of brain abscess. Authors analized 17 cases of pathologically and clinically proven brain abscess during the period of 39 months from Jan. 1978 to Mar, 1982 at National Medical Center. The results were as follows; 1. The sex ration 9 males to 8 females, and no sexdifference was seen, and the greatest number of cases were seen below the age of 30(65%). 2. The otogenicinfection was the most frequent predisposing factors(8 cases). Other predisposing factors were postoperative infection (2 cases), pulmonary infection (2 cases), and congenital heart disease(2 cases). The most common site ofinvolvement was posterior fossa(5 cases). Next was temporal lobe (4 cases), and temporoparietal lobe (3 cases). 3.Most common presenting symptoms were headache, fever, focal neurological signs, and dizziness. 4. Among the 22 brain abscesses of 17 patients, the msot frequent CT finding in precontrast scan was a low density surrounded by afaint dense or dense ring (11 cases). Next was purely low density (6 cases). Associated hydrocephalus was found in4 cases, and multiple or multiloculated abscess was seen in 4 cases. 5. In post contrast scan, brain abscessusually show complete, oval or round shaped, thin, evening righ enhancement with mild or moderate surroundingedema, but there was no specific enhancement.
Abscess ; Brain Abscess ; Brain ; Causality ; Diagnosis ; Dizziness ; Female ; Fever ; Headache ; Heart ; Humans ; Hydrocephalus ; Male ; Temporal Lobe

The adult trematodes, Fasciola hepatica, Eurytrema pancreaticum and Paramphistomum cervi, employed in this experiment were obtained from the cattle slaughtered at the local abbatoir. The worms selected and washed several times in normal sterilized saline solution. Each about ten of intact F. hepatica, fourty of E. pancreaticum, and twenty of P. cervi were incubated in 50 cc volume of special incubation flasks with incubation medium consisting of 10 cc. of Krebs-Ringer phosphate buffer(pH 7.4) The incubation medium was added C(14)-1-acetate and non-radioactive carrier Na-acetate so as to contain acetate concentration of 50 mg per cent . The worms were allowed to incubate for 5 hours in the Dubnoff metabolic shaking incubator at 38 C. After incubation period, respiratory CO(2) samples from central well of incubation flask were analysed for total CO(2) production rate and their specific activity of respiratory CO(2). The lactate and pyruvate appearance rates were determined by analyzing the lactate and pyruvate concentration in a medium after incubation. The glycogen samples isolated from worms were analyzed for the tissue concentration and their radioactivities in order to determine the turnover rate of glycogen pool. Radioactivities of these series of experiments were counted by an endwindow Geiger-Muller counter as an infinitely thin samples. The quantitative analysis of C(14)-acetate utilized by F. hepatica, E. pancreaticum and P. cervi were compared and discussed in this report. According to these data of the experiment, it is suggested that the fatty acid such as acetate may play a part of their oxidative process into the respiratory CO2 and the synthetic process into glycogen in the above species of trematodes.
parasitology ; helminth ; trematoda ; Fasciola hepatica ; Eurytrema pancreaticum ; Paramphistomum cervi ; acetate ; metabolism ; biochemistry ; CO(2) ; glycogen ; Krebs-Ringer phosphate buffer

The fowl nematode Ascaridia galli employed in this experiment was obtained from the intestine of domestic fowls at the local market. The worms selected and washed several times in normal sterilized saline solution. Each about thirty of intact worms were incubated in 50 cc volume of special incubation flasks with incubation mixture consisting of 10 cc of Krebs-Ringer phosphate buffer (pH 7.4) to which were added universally labeled C14-glucose and non-radioactive carrier glucose so as to contain concentration of 200 mg per cent. The worms were allowed to incubation for 3 hours in Dubnoff metabolic shaking incubator at 38 C. After incubation period, respiratory CO(2) samples from central well of incubation flask were analysed for total CO(2) production rate and their specific activity of respiratory CO(2). Glycogen samples isolated from worms were analysed for uptake rate was determined by analyzing the difference of the glucose concentration in a medium before and after incubation period . Radioactivities of these series of experiments were counted by an endwindow Geiger-Muller counter as an infinitely thin samples. The quantitative analysis of C(14)-glucose utilized by Ascaridia galli was summarized as the following . The glucose uptake rate by A. galli was a mean value of 1.73+/-0.32 micro-mole per hour per gram of wet wt. and total CO(2) production rate by the worms averaged 8.44+/-1.11 micro-mole per hour per gram of wet wt. The relative specific activity of respiratory CO(2) (R.S.A CO(2)) averaged 2.68+/-0.38 per cent . Thus , a man of 2.68 per cent of total CO(2) production rate was originated from the glucose in the medium, therefore the rate of CO(2) production derived from medium glucose was a mean of 0.23+/-0.03 micro-mole per hour per gram of wet wt. Thus, the average value of 2.58+/-0.55 percent (R.G.D CO(2))of glucose utilized by the worms from the medium glucose was oxidized to respiratory CO2. The tissue concentration of glycogen in A. galli was a mean of 22.59+/-1.18 miligram per gram of wet wt or 2.26+/-0.123 percent per gram, and the turnover rate of glycogen pool yielded with a mean of 0.17+/-0.04 percent per hour or 0.037+/-0.006 miligram per hour per gram of wet wt. Therefore, a mean value of 16.37+/-4.04 per cent (R.G.D gly) of glucose was incorporated to the glycogen. These data account for that at least 18.95 per cent of the utilized glucose by the worms participated in furnishing the oxidation into respiratory CO(2) and the synthetic process into glycogen. According to the above data of the experiment, it is suggested in the metabolic process of glucose by Ascaridia galli that the synthetic process into the glycogen is more active than the oxidative process into the respiratory CO(2).
parasitology ; helmith ; nematoda ; Ascaridia galli ; metabolism ; biochemistry ; glucose ; CO(2) ; radioactivity ; glycogen ; Krebs Rigner phosphate buffer