1.Comparison of Hirschberg Test with Prsim and Alternate Cover Test in Measuring the Ocular Deviation.
Journal of the Korean Ophthalmological Society 1993;34(3):252-256
Measurements of ocular deviation were obtained from 45 exotropes and 31 esotropes, using Hirschberg corneal reflex test, and prism and alternate cover test respectively. The mean angle of devation in exotropes was 27.42 +/- 8.60 delta by Hirschberg test, 27.80 +/- 8.11 delta by prism and alternate cover test. There was no significant difference between these two groups (p>0.05). The mean angle of deviation in esotropes was 28.55 +/- 12.92 delta by Hirschberg test, 31.58 +/- 13.08 delta by prism and alternate cover test. The difference between these two groups was significant (p<0.05). In patients whose angle kappa was zero and exotropes whose angle kappa was positive, there was no significant diHerence between the two tests. In esotropes whose angle kappa was positive, the mean angle of deviation was 29.74 +/- 15.59 delta by Hirschberg test, and 33.47 +/- 15.91 delta by prism and alternate cover test. The difference between the two groups was significant (p
2.Triple Procedure in Glaucoma Patients.
Jun Sang KIM ; Sang Don BOO ; Young Jae HONG
Journal of the Korean Ophthalmological Society 1992;33(10):964-969
The author reviewed the effectiveness of triple procedure in terms of the visual acuity and the intraocular pressure control after 6 months follow up of twenty-four consecutive glaucoma patients who was treated with triple procedure: trabeculectomy with simultaneous lens extraction and intraocular lens implanation. At 6 months after operation, the mean intraocular pressure was 7.0mmHg lower than the preoperative level, and the kind of glaucoma medication was decreased from 2.1 to 0.6. The visual acuity improved in 67% at two months and 93% at six months after operation, respectively. The several complications such as hyphema, shallow anterior chamber with wound leaking, posterior capsular opacity and uncontrolled intraocular pressure were appeared. Effectiveness of triple procedure in terms of intraocular pressure control and visual acuity improvement seems to be similar to that of the operation done separately.
Anterior Chamber
;
Cataract
;
Follow-Up Studies
;
Glaucoma*
;
Humans
;
Hyphema
;
Intraocular Pressure
;
Lenses, Intraocular
;
Trabeculectomy
;
Visual Acuity
;
Wounds and Injuries
3.Multiple Evanescent White Dot Syndrome.
Sang Don BOO ; Sahang Yeon KIM ; Oh Woong KWON
Journal of the Korean Ophthalmological Society 1992;33(9):925-929
Multipe Evanescent White Dot Syndrome is a clinical disorder of unknown etiology usually resulting in acute visual loss It affects primarily the retinal pigment epithelium and photoreceptors, Ocular manifestations may include multiple white dots at the level of the retinal pigment epithelium, granulaity of the macula, optic nerve swelling and anterior chamber and vitreous cells. Fluorescein angiogram discloses hyperfluorescence in association with the white spots and late staining and dye leakage from disc capillaries. We experienced a case of Multiple Evanescent White Dot Syndrome and reviewed the available literatures regarding this disease.
Anterior Chamber
;
Capillaries
;
Dental Caries
;
Fluorescein
;
Optic Nerve
;
Retinal Pigment Epithelium
4.A case of omphalocele and ectopia cordis with diaphragmatic defect.
Young Joo CHOI ; Kyung Don BAIK ; Hong Sup LEE ; Boo Soo HA ; Sang Kap KIM ; Jung Hee CHI
Korean Journal of Obstetrics and Gynecology 1992;35(7):1082-1087
No abstract available.
Ectopia Cordis*
;
Hernia, Umbilical*
5.Purtscher's-lke Retinopathy in Patients with Systemic Hypertension.
Sang Don BOO ; Sahng Yeon KIM ; Oh Woong KWON
Journal of the Korean Ophthalmological Society 1992;33(5):544-547
Since Purtscher's original discriptions similar clinical signs have been described following acute compressive neck or chest injuries, chest compression, val salva maneuvers, long bone fractures, acute pancreatitis and after childbirth. The appearance of Purtscher's retinopathy are believed to be due to ischemic episodes particularly in the end arterioles around the macula and disc. We experienced two cases of Purtscher's-like retinopathy in patients with systemic hypertension who had not any recent trauma history and reviewed the available literatures regarding this disease.
Arterioles
;
Fractures, Bone
;
Humans
;
Hypertension*
;
Neck
;
Pancreatitis
;
Parturition
;
Thoracic Injuries
;
Thorax
6.A Case of Lupus Cystitis.
Bo In LEE ; Sung Kyu PARK ; Yong Hak JUNG ; Chong Hyeon YOON ; Chun Sang BANG ; Hiun Suk CHAE ; Chang Don LEE ; In Sik CHUNG ; Sang Bok CHA ; Doo Ho PARK ; Boo Sung KIM
Korean Journal of Medicine 1997;53(3):440-444
Systemic lupus erythematosus is a disease of unknown cause which involves various organs and primary involvement of urinary bladder is very rare. We experienced a case of a female patient with SLE and urologic manifestations (interstitial cystitis, hydroureters and hydronephrosis), which were resolved spontaneously without any immunosuppressive therapy. There was no significant correlation between clinical course and disease activity index.
Cystitis*
;
Female
;
Humans
;
Lupus Erythematosus, Systemic
;
Remission, Spontaneous
;
Urinary Bladder
7.Upper Gastrointestinal Bleeding in Liver Cirrhosis : clinical and endoscopic findings.
In Sik CHUNG ; Boo Sung KIM ; Chang Don LEE ; Doo Ho PARK ; Soo Hyuk OH ; Jae Kwang KIM ; Sang Won HAN ; Sung Soo KIM ; Seung Kew YOON ; Myug Gyu CHOI
Korean Journal of Gastrointestinal Endoscopy 1995;15(1):33-39
It is well known that the main source of upper gastrointestinal(UGI) bleeding in patients with liver cirrhosis is the variceal rupture of esophagus. But, peptic ulcer disease, congestive gastrophathy, and gastric varices are frequently found by endoscopic examination in patients with liver cirrhosis. These lesions are related to UGI bleeding. It is necessary to verify the causes of bleeding in liver cirrhosis, and evaluate the influencing factors related with UGI bleeding, and define the endoscopic findings of bleeding in liver cirrhosis. We reviewed the records of 145 episodes of UGI bleeding in cirrhosis, with endoscopy performed within 24 hours of entry, and report here the bleeding sites, influencing factors related with UGI bleeding, and endoscopic findings. The most common bleeding site was the esophageal varices(66.9%). Other bleeding lesions included gastric ulcer(8.3%), congestive gastrophathy(6.9%), undetermined origin(6.9%), duodenal ulcer(6.2%), gastric varices(2.1%), esophageal varices+gastric ulcer(1.4%), and esophageal varices+duodenal ulcer(1.4%). Endoscopic features of bleeding esophageal varices were identified as Spurting(2.1%), Oozing(11.3%), Red plugh(10,3 %), White plugh(14.4%), and Red-color sign(61.9%). In bleeding esophageal varices, gradeIV varices(41.2%) had a significantly higher association with bleeding than gradeI varices(2.1%), gradeII varices(22.7%), and gradeIII varices(34.0%). Endoscopic features of bleeding gastric ulcer were identified as Spurting(8.3%), Oozing(25.0%), Blood clots(58.3%), and Exposed blood vessels on ulcer base(41.7%). Endoscopic features of bleeding duodenal ulcer were identified as Oozing(44.4%), Blood clots(55.6 %), and Exposed blood vessels on ulcer base(55.6%). We found no difference in the bleeding sources according to etiology of cirrhosis(P>0.05). Bleedings due to the variceal rupture of esophagus were more frequently found in Child class B(71.2%) and C(75.0%) than A(34.8%)(P<0.05).
Blood Vessels
;
Child
;
Duodenal Ulcer
;
Endoscopy
;
Esophageal and Gastric Varices
;
Esophagus
;
Estrogens, Conjugated (USP)
;
Fibrosis
;
Hemorrhage*
;
Humans
;
Liver Cirrhosis*
;
Liver*
;
Peptic Ulcer
;
Rupture
;
Stomach Ulcer
;
Ulcer
8.Comparison on the Efficacy and Safety of Biphenyl Dimethyl Dicarboxylate and Ursodeoxycholic Acid in Patients with Abnormal Alanine Aminotransferase: Multicenter, Double-blinded, Randomized, Active-controlled Clinical Trial
Sae Hwan LEE ; Gab Jin CHEON ; Hong Soo KIM ; Young Don KIM ; Sang Gyune KIM ; Young Seok KIM ; Soung Won JEONG ; Jae Young JANG ; Boo Sung KIM
The Korean Journal of Gastroenterology 2022;79(1):52-53
9.A Case of Strongyloides Stercoralis Infection of Stomach in Association with Meningitis.
Chong Hyeon YOON ; Hyung Ook KIM ; Mi Young KIM ; Won Young LEE ; Sung Soo KIM ; Sang Won HAN ; Young Sang YANG ; Seung Kew YOON ; Chang Don LEE ; Doo Ho PARK ; Boo Sung KIM
Korean Journal of Medicine 1997;52(4):550-553
Strongyloides stercoralis hyperinfection syndrome is a rare complication of strongyloidiasis that frequently occurs in immunosuppressed patients. The parasite ordinarily localizes in the small intestines, especially in the duodenal and jejunal part. Reports of gastric involvement are rare. We report a case of an immunosuppressed patient who had severe S. stercoralis infection of the stomach in association with purulent meningitis.
Gastritis
;
Humans
;
Intestine, Small
;
Meningitis*
;
Parasites
;
Stomach*
;
Strongyloides stercoralis*
;
Strongyloides*
;
Strongyloidiasis
10.Mutations of hepatitis C virus 1b NS5A 2209-2248 amino acid sequence is not a edictive factor for response to interferon-alpha therapy and development of patocellular carcinoma.
Si Hyun BAE ; Young Min PARK ; Duck Gi YOO ; Jong Young CHOI ; Byung Hun BYUN ; Jin Mo YANG ; Chang Don LEE ; Sang Bok CHA ; Doo Ho PARK ; Boo Sung KIM
Journal of Korean Medical Science 2000;15(1):53-58
Genetic changes between codons 2209 and 2248 of NS5A of genotype 1b hepatitis C virus (HCV-1b) have been reported to be associated with the sensitivity to interferon-alpha (IFN-alpha). The present study was performed to analyze such relationship in Korean patients with chronic hepatitis C and HCV-1b (n=19), including 12 chronic hepatitis C patients treated with IFN-alpha, 3 chronic hepatitis C patients without treatment as controls, and 4 patients with hepatocellular carcinoma (HCC). Two serum samples, before and after the treatment, were analyzed for the mutations by reverse transcription-polymerase chain reaction, cloning and sequencing. The mutations were identified in 32% (6/19), including five intermediate type (1-3 mutations) and one mutant type (4 or more). In 12 patients treated with IFN-alpha, the number of amino acid substitutions in NS5A2209-2248 was not associated with outcome of the treatment.
Adult
;
Aged
;
Amino Acid Sequence
;
Antiviral Agents/therapeutic use*
;
Base Sequence
;
Carcinoma, Hepatocellular/virology*
;
Carcinoma, Hepatocellular/blood
;
Codon
;
Female
;
Genotype
;
Hepatitis C, Chronic/virology*
;
Hepatitis C, Chronic/drug therapy*
;
Hepatitis C, Chronic/blood
;
Hepatitis C-Like Viruses/isolation & purification
;
Hepatitis C-Like Viruses/genetics*
;
Hepatitis C-Like Viruses/classification
;
Human
;
Interferon-alpha/therapeutic use*
;
Liver Neoplasms/virology*
;
Liver Neoplasms/blood
;
Male
;
Middle Age
;
Molecular Sequence Data
;
Mutation*
;
Prognosis
;
Reverse Transcriptase Polymerase Chain Reaction