1.Repolarization Abnormalities after Successful Radiofrequency Catheter Ablation of Accessory Pathway in Patients with the Wolff-Parkinson-White (WPW) Syndrome.
Jang Ho BAE ; Yoon Nyun KIM ; Seong Wook HAN ; Dae Woo HYUN ; Yi Chul SYNN ; Kee Sik KIM ; Kwon Bae KIM ; Sang Min LEE
Korean Circulation Journal 1998;28(9):1493-1501
BACKGROUND AND OBJECTIVES: The repolarization abnormalities, after radiofrequency catheter ablation (RFCA) of accessory pathway (AP) in patients with Wolff-Parkinson-White (WPW) syndrome, is commonly appeared in standard 12 lead electrocardiogram (ECG) as inverted T waves. We analyzed the serial ECGs after RFCA of AP in patients with WPW syndrome, in order to understand the repolarization abnormalities after RFCA. MATERIALS AND METHOD: The study patients were consisted of ninety two patients (mean age: 35 years old, male: 56 patients) out of 157 patients whose ECGs were taken at before, immediately after, one day, one, four, eight, twelve week (s) after RFCA from December 1992 to July 1997. RESULTS: The seventy three patients (79%) out of ninety two patients showed the repolarization abnormalities and the thirteen patients (14%) showed normalization of secondary T wave changes immediately after RFCA. In contrast, six patients (7%) did not show any T wave changes after RFCA and they had left lateral AP. The lead that most frequently showed inverted T wave changes after RFCA was lateral lead (lead I, aVL) in case of left lateral AP and inferior lead (II, III, aVF) in case of other APs. The incidence of repolarization abnormalities after RFCA was significantly higher in patients whose preRFCA QRS duration is longer (> or =0.12 sec). The concordance rate of repolarization abnormalities after RFCA was 86% (63 patients of 73 patients showing repolarization abnormalities after RFCA). The normalization of repolarization abnormalities after RFCA was acquired in sixty four patients (94%) out of sixty eight patients who showed repolarization abnormalities and followed up to twelve weeks after RFCA. The mean time interval to the normalization of repolarization abnormalities after RFCA was 4.3+/-3.2 weeks. The time interval to the normalization of repolarization abnormality after RFCA was not related with age, AP or preRFCA QRS duration. CONCLUSION: The ECG lead, in which the repolarization abnormalities occurs after RFCA , is related with the location of the AP. The repolarization abnormalities after RFCA were more common in patients with longer preRFCA QRS duration. The repolarization abnormalities after RFCA could not be understood only by cardiac memory.
Adult
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Catheter Ablation*
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Electrocardiography
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Humans
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Incidence
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Male
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Memory
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Wolff-Parkinson-White Syndrome
2.Antipsychotics and the Abnormality of Fasting Glucose, Total Cholesterol in Schizophrenia.
Joong Sun LEE ; Jae Hyun LEE ; Jeong Won JEON ; Dong Eun LEE ; Sang Chul SYNN ; Joon Ho AHN ; Oh Su HAN ; Chang Yoon KIM
Korean Journal of Psychopharmacology 2005;16(1):33-41
OBJECTIVE: The concerns about significant weight gain induced by antipsychotics have been recently increased. It raised an issue about the possible effect of antipsychotics on the glucose and lipid metabolism. To address this issue, we investigated the prevalence of abnormal glucose metabolism (impaired fasting glucose (110 mg/dl
Antipsychotic Agents*
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Blood Glucose
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Cholesterol*
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Diagnostic and Statistical Manual of Mental Disorders
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Fasting*
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Glucose*
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Haloperidol
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Humans
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Inpatients
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Lipid Metabolism
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Medical Records
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Metabolism
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Outpatients
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Prevalence
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Schizophrenia*
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Weight Gain
3.Clinical Status in Patients Who Restrictive Pattern on Doppler Transmitral Flow Pattern.
Jang Ho BAE ; Kee Sik KIM ; Chang Yeob HAN ; Seung Wook HAN ; Dae Woo HYUN ; Yi Chul SYNN ; So Young PARK ; Sang Joon LEE ; Yoon Nyun KIM ; Kweon Bae KIM
Journal of the Korean Society of Echocardiography 1997;5(1):42-50
BACKGROUND: Restrictive pattern on Doppler transmitral flow pattern represent reduced left ventricular compliance and associated with poor prognosis in patients with systolic dysfunction due to congestive heart failure or myocaridal infarction. Although there are many clinical evaluation about clinical significance of restrictive transmitral flow pattern, investigation about what kinds of disease reveal the characteristic restrictive transmitral flow pattern and significance according to criteria of restrictive transmitral flow pattern is few. Therefore, we have analyzed patients with restrictive transmitral flow pattern in order to evaluate clinical diagnosis and clinical significance according to criteria of restrictive transmitral flow pattern. METHODS: The study population consisted of 229 patients(male 129 patients, female 102 patients, mean age 40.6 years old) who show E/A ratio p 2 on Doppler echocardiography from september 1994 to aprial 1996. We have reviewed the medical records of that patients. RESULTS: 1) In case of patients more than 2 at E/A ratio, we found that subjects not related with cardiovascular diseases were 76 persons(33.2%), valvular heart disease 75 patients(32.3%), ischemic heart disease 25 patients(10.9%), cardiomyopathy 16 patients(6.9%). Among valvular heart disease, mitral regurgitation was most frequently observed(44.5%). In these patients, patients with left ventricular systolic dysfunction were 60 patients(26.2%). 2) Patients more than 2 at E/A ratio and less than 150msec at deceleration time of E wave were 126 patients(55.0%). In these patients, we found that valvular heart disease was also most frequently observed(49 patients, 38.8%), subjects not related with cardiovascular diseases 30 persons(23.8%), cardiomyopathy 15 patients(11.9%),pericarditis 7 patients(5.6%), hypertension 3 patients(2-3%). Patients with left ventricular systolic dysfunction in this group were 39 patients(31.0%). CONCLUSION: Although restrictive transmitral flow pattern on Doppler echocardiography represents reduced compliance of left ventricle or severe heart failure in patients with symptoms of congestive heart failure, this pattern also may be seen in persons not related with cardiovascular disease. Therefore, when making dicision about clinical significance of restrictive pattern, one should consider about any factors can influece the transmitral flow pattern and correlate the clinical diagnosis with mitral flow velocity.
Cardiomyopathies
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Cardiovascular Diseases
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Compliance
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Deceleration
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Diagnosis
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Echocardiography, Doppler
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Female
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Heart Failure
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Heart Valve Diseases
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Heart Ventricles
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Humans
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Hypertension
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Infarction
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Medical Records
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Mitral Valve Insufficiency
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Myocardial Ischemia
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Prognosis