No abstract available.
Anemia* ; Child* ; Humans

No abstract available.
Leukemia, Erythroblastic, Acute*

No abstract available.
Anemia, Hemolytic, Congenital Nonspherocytic*

PURPOSE: To compare the efficacy, predictability, stability and safety of excimer laser photorefracive keratectomy(PRK) for mypia and photoastigmatic refractive keratectomy(PARK) for compound myopic astigmatism. METHODS: Two-hundred-three eyes(118 eyes <-7D spherical equivalent, 85 eyes> or =-7D spherical equivalent) received excimer laser correction for compound myopic astigmatism and 152 eyes(116 eyes <-7D, 36 eyes > or =-7D) for simple myopia. A VISX 20/20B VisionKeyTM excimer laser was used to perform either PARK or PRK. Visual acuity with and without correction, refraction, IOP, corneal haze, and topography were evaluated at 1, 3, 6, and 12 months postoperatively. All patients were followed up for more than 12 months. RESULTS: Postoperative refraction were generally stable after 3 months without significant early overcorrection. At 12 months, 110(94.8%) eyes that underwent PRK and 104(88.1%) eyes that underwent PARK achieved UCVA of 20/30 or better in the group who had lower than -7D correction. For eyes treated with -7D or more, these figures were 31(86.1%) eyes after PRK and 57(67.1%) eyes after PARK. The incidence of within 1D of plano refraction at 1 year follow-up were 97.4% after PRK and 93.2% after PARK in group who had lower than -7D correction. For eyes treated with -7D or more, there figures were 80.6% after PRK and 70.6% after PARK. CONCLUSIONS: Myopia with or without astigmatism was successfully treated in most of the eyes using PRK or PARK with VISX 20/20B VisionKeyTM excimer laser. The predictability and stability of the postoperative refraction during the first 12 months seem to be quite reliable. Futher improvement of excimer laser system and software should increase the clinical outcomes and safety of refractive procedures.
Astigmatism* ; Follow-Up Studies ; Humans ; Incidence ; Lasers, Excimer* ; Myopia* ; Photorefractive Keratectomy ; Visual Acuity

The purpose of this study was to evaluate the occurrence of delayed epithelial healing(DEH) and the factors associated with it after excimer laser photorefractive keratectomy(PRK) and to assess whether there are any difference in the clinical outcomes between the eyes of DEH group and normal epithelial healing(NEH) group. This retrospective study was done in 554 consecutive eyes which had eximer laser PRK(VISX 20/20B WisionKey system with central island removal program) by one surgeon(S.B.L) between September 1994 and April 1997 at Yeungnam University Medical Center. Mean reepithelializion time of all 554 eyes was 3.1+/-1.3 days. Delayed epithelial healing beyond postoperative 5 and 7 days after exicimer laser PRK were noted in 30 eyes(5.4%) and 8 eyes(1.4%) of all 554 eyes, respectively. Mean reepithelialization time of DEH group was 7.1 days(range 5~12 days). Occurrence of DEH after excimer laser PRK was not depending on sex, age, laterality, amount of attempted correction(-6D or -6D), type of procedure(PRK vs. PARK), use of Maclof, the order of operation(type eye vs. second eye) or the type of soft ware(version 3.20 vs. 4.01)(All: p>0.05). At 6 months after surgery, 16 eyes(64%) of total 25 eyes of DEH group achieved UCVA of 0.7 or better, and 14 eyes(56%) were within +/-1D of emmetropia. In the NEH group. 349 eyes(84.7%) were UCVA of 0.7 or better, and 365 eyes(88.4%) were within +/-1D of emmetropa. There was statistically significant decrease in the clinical outcome of DEH group being compared with NEH group(p<0.05) In conclusion, prompt management for complete epithelial wound healing should be done in the cases of delayed epithelial healing after excimer laser PRK because it can cause the decrease in clinical outcome. Further studies assessing the effects of numerous topical medications, preservatives and software on epithelial healing after exicimer laser PRK would be performed.
Academic Medical Centers ; Emmetropia ; Lasers, Excimer* ; Photorefractive Keratectomy* ; Retrospective Studies ; Wound Healing* ; Wounds and Injuries*

A 24-year-old female was seen with multiple, pinkish to skin colored and brownish to black pigmented macules, papules, patch and plaque on the face, neck, upper chest, extensor surface of both forearms and dorsal hands. Histopathological diagnoses from the 75 skin biopsy specimens taken during the follow-up period of 22 months include 29 skin tumors : one malignant melanoma, one precancerous melanosis, 16 basal cell carcinamas, four squamous cell carcinomas, four actinic keratoses, one melanoacanthoma, one keratoacanthoma and one angiofibroma. It was discussed that melanoacanthoma would be considered as the one of the associated beniign skin tumors in xeroderma pigmentosum.
Angiofibroma ; Biopsy ; Carcinoma, Squamous Cell ; Diagnosis ; Female ; Follow-Up Studies ; Forearm ; Hand ; Humans ; Ichthyosis* ; Keratoacanthoma ; Keratosis, Actinic ; Melanoma ; Melanosis ; Neck ; Skin* ; Thorax ; Xeroderma Pigmentosum* ; Young Adult

The relationship between intraorbital hydroxyapatite implantation and drilling was studied in 85 cases of 85 patients from September 1991 through December 1996 in the Separtment of Ophthalmology, Yeungnam University College of Medicine. The incidence of drilling after intraorbital implantation and the causes of not being able to drill were evaluated. Postoperative extraocular muscle and prosthetic motility of the cases with and without drilling were reviewed. Drilling was performed in 39 cases(45.9%). Forty-six cases were not received drilling due to mildly contracted, tight socket(17 cases), satisfactory prosthetic motility without drilling (13 cases), limitation of extraocular muscle motility(9 cases), thin prosthesis(4 cases) and exposure of implant(3 cases). A fter the follow-up period of 6-56 months(mean 18 months), postoperative prosthetic motility was satisfactory in 30 cases(76.9%) in drilling cases and 12 cases(26.1%) in non-drilling cases.
Durapatite ; Follow-Up Studies ; Humans ; Incidence ; Ophthalmology ; Orbit* ; Orbital Implants*

PURPOSE: There are no clear-cut guidelines of how to treat patients who have failed after a tension-free midurethral sling (MUS) procedure. We describe our experience with repeat MUS procedures and transvaginal shortening of the previously implanted tape for those patients with an initially failed MUS procedure. MATERIALS AND METHODS: We reviewed the medical records of the patients who failed with their initial MUS procedure and then had a second operation. Of the 20 women, 14 patients had repeat MUS and another 6 patients underwent shortening of the implanted tape. Repeated MUS was done by either the retropubic or transobturator pathway. Shortening of the tape was done with a metal hemoclip to shorten the previously implanted tape. The preoperative characteristics and the intraoperative and postoperative data were assessed by reviewing the operative notes, medical records and office notes. RESULTS: The mean interval between the first and repeat procedures was 8.4 months (range: 1-48). The mean follow up time after the second operation was 29.9 months (range: 7-70). Seven patients underwent repeat MUS instead of tape shortening because the implanted tape had migrated or severe adhesions were noted on the intraoperative findings. Ten (71.4%) of 14 patients who underwent repeat MUS achieved full continence, while 4 patients (28.6%) had significant improvement. Of the patients with tape shortening, 4 (66.6%) achieved full continence, one (16.7%) improved and one (16.7%) was failed. CONCLUSIONS: Based on our limited experience, a repeat MUS sling procedure or tension revision of the tape might be an effective treatment for the patients with failed MUS.
Animals ; Female ; Follow-Up Studies ; Humans ; Medical Records ; Mice ; Reoperation ; Suburethral Slings* ; Treatment Failure ; Urinary Incontinence*

Clinical and bacteriological studies were made on 37 cases of infantile and childhood shigellosis treated at pediatric department of St. Mary's hospital in Dae Jon from Jan. 1978 to Dec. 1978. The following results were obtained. 1. In sex distribution 21 were male and rest of them were female, and the M/F ratio was 1.8:1.0. 2. The peak age incidence showed the children of 1 to 6 years old. 3. The most frequent symptom was fever(76%) and abdominal pain was next. 4. S. flexneri was most frequentkly isolated (62.2%) and the next was S. sonnei(35.1%). 5. The result of sensitivity test in this study revealed that tobramycin was most commonly effective (92%) and cephaloridin was next. Ampicillin was less sensitive (22%) than the previous reports.
Abdominal Pain ; Ampicillin ; Cephaloridine ; Child ; Daejeon* ; Dysentery, Bacillary* ; Female ; Humans ; Incidence ; Male ; Sex Distribution ; Tobramycin

PURPOSE: Extra-thyroidal extension has been recognized as a poor prognostic factor for increased regional recurrence risk in papillary thyroid carcinoma, and is known to require treatment that is more aggressive. In the recent UICC TNM 6th Classification, an extra-thyroidal extension was divided into a minimal extra-thyroidal extension (T3) and a massive extra-thyroidal extension (T4). The aim of this study was to investigate the clinical effect of a minimal extra-thyroidal extension of a papillary carcinoma for the recurrence of regional cervical lymph nodes. METHODS: We retrospectively studied 154 patients with papillary thyroid carcinoma where a thyroidectomy was performed from Feb. 2003 to May. 2006 at the Department of Surgery, with the exclusion of 6 patients with a massive extra-thyroidal extension. We divided the cases into a no extra-thyroidal extension group and a minimal extra-thyroidal extension group according to the grading of the extra-thyroidal extension. The grading of the extra-thyroidal extension was based on both pathological findings and intraoperative surgical findings. Clinicopathological factors associated with each group were analyzed by univariate and multivariate analysis. We divided the cases into two groups according to age (<45 yrs, > or =45 yrs) and lymph node status (positive, negative), and compared each group with regards to disease free survival according to the grading of the extra-thyroidal extension. RESULTS: By univariate analysis, a minimal extra-thyroidal extension was related to lymph node metastasis, tumor size, mutifocality (P<0.05), and was not related to cervical lymph node recurrence statistically (P=0.108). Cervical lymph node recurrence was related to being male, lymph node metastasis and tumor size (P<0.05). By multivariate analysis, a minimal extra-thyroidal extension was independently related to tumor size, multifocality, and lymph node metastasis (P<0.05). In both groups with regards to age and lymph node status, a minimal extra-thyroidal extension was not statistically related to disease free survival (P>0.05). CONCLUSION: We need to downstage to less than T3 for a minimal extra-thyroidal extension because there is no significant difference in disease free survival according to the grading of an extra-thyroidal extension in patients with papillary thyroid carcinoma.
Carcinoma, Papillary ; Classification ; Disease-Free Survival ; Humans ; Lymph Nodes* ; Male ; Multivariate Analysis ; Neoplasm Metastasis ; Recurrence* ; Retrospective Studies ; Thyroid Gland* ; Thyroid Neoplasms* ; Thyroidectomy