No abstract available.
Carcinoma, Papillary* ; Thyroid Gland* ; Tretinoin*

PURPOSE: We compared the first postoperative diagnostic and post-therapy scans of patients who received therapeutic doses of I-131, to investigate the difference in clinical outcomes between patients with concordant findings of diagnostic and post-therapy scans and patients with discrepant (more lesions in post-therapy scan) findings. MATERIALS AND METHODS: The first postoperative diagnostic and post-therapy radioiodine scans of one hundred forty three patients with well differentiated thyroid carcinoma were reviewed. Diagnostic scans were obtained following ingestion of 185 MBq of I-131 and post-therapy scans were obtained after therapeutic dose of 3.7~9.3 GBq of I-131. Successful ablation was defined as no radioiodine uptake on diagnostic radioiodine scan and normal range of serum thyroglobulin level (<10 ng/ml) during serum TSH elevation. RESULTS: Discrepant scan findings were noted in 25 (17.5%) patients. Twenty-two patients (15.4%) showed more lesions in post-therapy scan and 3 patients (2.1%) showed stunning effect. Nine (64.3%) of 14 patients with distant metastasis revealed metastatic lesion(s) only on post-therapy scan. Stunning effect was considered as sublethal damage in 1 patient and treatment by a diagnostic dose in 2 patients. Ablation was achieved in 52.4% (75/143) of all patients. Ablation rate and mean cumulative radioiodine dose were not different statistically between concordant and discrepant groups. CONCLUSION: There were 17.5% difference between diagnostic and post-therapy scan findings when using 185 MBq of I-131 as a diagnostic dose. However, 64.3% of distant metastases were revealed only on post-therapy scan. Ablation rate and mean cumulative radioiodine dose were not different statistically between concordant and discrepant groups. The stunning effect was considered as not only sublethal damage but also treatment by a small diagnostic dose of radioiodine.
Eating ; Humans ; Neoplasm Metastasis ; Reference Values ; Thyroglobulin ; Thyroid Gland* ; Thyroid Neoplasms*

No abstract available.
Gait* ; Humans ; Spinal Cord Diseases*

No abstract available.
Adult* ; Humans

No abstract available.
Cleidocranial Dysplasia*

The authors presented a clinical review on 67 cases of lagophthalmos in leprosy, who were treated in Leprosy Mission Hospital from 1970 to 1978. The static procedure was performed on 59 eyes of 45 patients. The tarsorraphy was simple and quick method, and has hitherto been the main stay of surgical procedure employed for correction of lagophthalmos. Although technically a simple procedure, its disadvantages are permanent narrowing of palpebral fissure, epiphora and chronic conjunctivitis due to exposure of the bulbar conjunctiva on effort or during sleep. The sling technique with silk was temporary in its effectiveness. The sling technique with fascia lata also tender to stretch in time resulting in recurrence of the ectropion. For these reason static procedure is considered unsatisfactory as a definite surgical procedure for the correction of lagophthalmos in leprosy. The lagophthalmos in leprosy was not found in association with temporal nerve paralysis. So authors performed temporal muscle transfer on 18 eyes of 12 patients, the same as originally devised by Gillies. 12 out of 18 eyes had no residual lagophthalmos. 3 eyes had fair results due to low tension of the transfer. One patient (2 eyes), who was operated during acute phase of lepra reaction, had poor results due to low tension of the transfer. One eye was a failure due to adhesion and infection of the transfer. Ectropion of the lower lid in one eye was produced as a result of placing the fascial strip too far away from the lid margin. The Gillies technique requires wide surgical field and takes a long time to operate. Nevertheless, this technique to activate a circumocular sling of its own attached fascia restores natural contour of the eye and enables the patient to close his eye completely on effort or during sleep. This surgical procedure was permanent in result and considered the method of choice for the correction of lagophthalmos in leprosy. Even when it fails, Gillies technique for lagophthalmos is much better than static procedure.
Conjunctiva ; Conjunctivitis ; Ectropion ; Fascia ; Fascia Lata ; Humans ; Lacrimal Apparatus Diseases ; Leprosy* ; Missions and Missionaries ; Paralysis ; Recurrence ; Silk ; Temporal Muscle

An analytic study on 431 cases of cardiac conduction disturbance has been made by review of the clinical records and electrocardiograms taken from the adult patients registered at Kyung Hee University Hospital for 3 years from May, 1973 to April, 1976. 1. The total incidence of conduction disturbance was 6.50%, the atrioventricular block 3.14% and the intraventricular block was 3.36% of total 6,616 cases of E.C.G. reviewed. Among of these, the first degree atrioventricular block was 3.02% which was the most common occurred one, the incomplete right bundle branch block was 2.25% and the complete right bundle branch block was 0.57%. 2. The ratio of male to female was 1.6:1 for the first degree atrioventricular block, and 1.6:1 for the incomplete right bundle branch block, 2.5:1 for the complete atrioventricular block, 2:1 for the left bundle branch block, and 1.7:1 for the complete right bundle branch block. The first degree atrioventricular block was seen most frequently in the fifth and sixth decade of age group, and the third degree block was over 40 years. The incomplete right bundle branch block in order was forth decade, third decade and fifth decade. The complete right bundle branch block and left posterior hemiblock were common in the sixth decade. The left bundle block and the posterior hemiblock were common in fifty years of age group. 3. The cardinal underlying diseases of the first degree atrioventricular block among cardiac diseases group in order of frequency were: hypertensive heart disease (25.0%) arteriosclerotic heart disease (8.0%) and rheumatic valvular heart disease (5.0%). The most common etiology of those non-cardiac disease group was neuropsychiatry disorder (11.5%) and the next was infection (11.0%). 4. All of the complete atrioventricular block were associated with the cardiac disease, that is, 57.0% with arteriosclerotic heart disease, 28.5% with pericarditis and 14.3% with hypertensive heart disease, respectively. 5. The cardinal underlying disease of the incomplete right bundle branch block in order of frequency were: hypertensive heart disease (10.7%), arteriosclerotic heart disease (8.1%) among the cardiac disease group, and infections (15.4%) among the non-cardiac disease group. The incidence of healthy persons was 14.1%. 6. Those of complete right bundle branch block in order of frequency were: arteriosclerotic heart disease (13.2%), and hypertensive heart disease (10.1%) among the cardiac disease group, and infection(13.2%) and neurosis (10.1%), respectively among the non-cardiac disease group. 7. The major etiologies of the left bundle branch block was hypertensive heart disease and arteriosclerotic heart disease (33.3% each), and that of left posterior hemiblock was showed arteriosolerotic heart disease and cor-pulmonale. The most common etiological disease of the left anterior hemiblock was hypertensive heart disease in cardiac disease group, and infection and gatrointestinal disease in non-cariac disease group. 8. The abnormal electrocardiographic findings with the first degree atrioventricular block were left ventricular hypertrophy (24.8%), sinus tachycardia (11.0) and sinus bradycardia (5.8%). Those with the complete atrioventricular block were right ventricular hypertrophy (15.8%) and left bundle branch block (15.8%). In complete right bundle branch block, the majority (52.5%) showed single sign without other abnormality on E.C.G. In the left bundle branch block, there were 18.9% of left ventricular hypertrophy and 15.7% of first degree atrioventricular block. In the left anterior hemiblock, there were 28.5% of right bundle branch block, and 19.0% of right ventricular hypertrophy. In the left posterior hemiblock, there were 40.0% of atrial fibrillation and 20.0% of left atrial hypertrophy.
Adult ; Male ; Female ; Humans ; Incidence

No abstract available.
Marchiafava-Bignami Disease ; Wernicke Encephalopathy

OBJECTIVE: The purpose of this study was to investigate a correlation between the muscle strength of trunk and bone mineral density (BMD) in women. METHOD: A total of 218 healthy women participated in the study. Their age ranged from 26 to 72 years. Dual X-ray absorptiometry was used to measure the BMD of lumbar spine and the trunk muscle strength was assessed by a Cybex NORMTM system. Under the standard criteria of World Health Organization for the dual X-ray absorptiometry analysis, we divided spine T-score into three groups(group 1: osteoporosis, group 2: osteopenia, and group 3: normal). RESULTS: The data revealed a siginificant correlation (r= 0.455, p=0.0001) between the age and BMD of lumbar spine. Trunk extensor muscle strength revealed 56.27+/-18.08 Nm (mean+/-SD) in osteoporosis group, 72.84+/-21.69 Nm in osteopenic group, and 77.90+/-22.28 Nm in normal group. Trunk flexor muscle strength was 82.73+/-23.30 Nm in osteoporosis group, 86.00+/-19.77 Nm in osteopenic group, and 98.91+/-18.29 Nm in normal group. CONCLUSION: These results indicated that the trunk extensor muscle was weaker than the flexor muscle in osteoporotic group. As the bone mineral density reduced, the strength of both trunk extensor and flexor decreased. However the weakness of trunk flexor occurred at the earlier stage of osteoporosis than the weakness of trunk extensor.
Absorptiometry, Photon ; Bone Density* ; Bone Diseases, Metabolic ; Female ; Humans ; Muscle Strength* ; Osteoporosis ; Spine ; World Health Organization

OBJECTIVE: To evaluate (1) the effect of chronic low back pain on bone mineral density, and (2) the effect of chronic low back pain on trunk muscle strength in women. METHOD: Subjects were 118 women patients (ages of 28~65 years) suffering from chronic low back pain more than three months and control groups were 218 healthy women (age of 26~72 years). We measured bone mineral density (BMD) at the lumbar spine and proximal femur using Dual X-ray absorptiometry and trunk muscle strength using Cybex 660 dynamometer. RESULTS: There was no significant difference between groups in lumbar spine BMD, in proximal femur BMD, or in trunk flexor muscle strength. However, trunk extensor muscle strength was reduced significantly in patient group. Trunk extensor muscle peak torque was 64.69+/-18.48 Nm in the patient group and 73.84+/-22.50 Nm in the control group in 30 degrees/sec, and 58.65+/-18.59 Nm in the patient group and 65.68+/-20.28 Nm in the control group in 60 degrees/sec. CONCLUSION: The results suggest that chronic low back pain does not affect the BMD. However, it causes trunk extensor muscle weakness; therefore, trunk extension exercise will be help to the patients with chronic low back pain.
Absorptiometry, Photon ; Back Pain ; Bone Density* ; Female ; Femur ; Humans ; Low Back Pain* ; Muscle Strength* ; Muscle Weakness ; Spine ; Torque