No abstract available.
Meconium*

Our purpose is to describe a successful twin pregnancy and delivery after intracytoplasmic sperm injection (ICSI) followed by calcium ionophore with spermatozoa from a globozoospermic man. On the second attempt of ICSI, all of eight metaphase II oocytes were fertilized with treatment with calcium ionophore. Day 3 transfer of six normally developing embryos resulted in an ongoing twin pregnancy, and two preterm healthy babies were born in the 33th week of gestation. To the best of our knowledge, this is the first report of pregnancy and delivery after ICSI followed by calcium ionophore with spermatozoa from a globozoospermic man in Korea.
Calcium* ; Embryonic Structures ; Humans ; Metaphase ; Oocytes ; Pregnancy ; Pregnancy, Twin* ; Sperm Injections, Intracytoplasmic* ; Spermatozoa*

No abstract available.
Bronchopulmonary Sequestration*

Succinylcholine-induced prolonged neuromuscular blockade may occur in patients with either a low level of plasma cholinesterase activity or genotypically abnormal form of that enzyme. We experienced a case of succinylcholine-induced prolonged apnea due to a low level of plasma cholinesterase activity. A 31-year-old woman, full term primigravida, underwent cesarean section for breech presentation under general anesthesia. Familial and past medical history were nonspecific and preoperative physical and laboratory findings were within normal range. After operation, delayed apnea was detected and lasted for about one hour. We performed controlled and assisted ventilation for two and half hours. Plasma cholinesterase activity measured 30.00 IU/L (colorimetric method, normal value: 1130~1960 IU/L) at the first postoperative day. She was discharged on 7th postoperative day without any sequelae. From follow-up study after six months, it measured 1.02 U/ml (EIA, normal value: 7~9 U/ml).
Adult ; Anesthesia, General ; Apnea* ; Breech Presentation ; Cesarean Section* ; Cholinesterases* ; Female ; Follow-Up Studies ; Humans ; Neuromuscular Blockade ; Plasma* ; Pregnancy ; Reference Values ; Ventilation

BACKGROUND AND OBJECTIVES:The chemical labyrinthectomy with aminoglycoside is a good method for vertigo control in Meniere's disease. It is relatively non-invasive and easy procedure, but hearing loss is a awful complication. We aimed to evaluate the relationship between the change in the degree of canal paresis in bithermal caloric test and the degree of hearing change. MATERIALS AND METHODS:Sixty-five patients of Meniere's disease who underwent chemical labyrinthectomy with streptomycin between October 1997 and December 2001 were included in this study. The minimum follow-up period for the patients was 24 months. Medical records were analyzed retrospectively. Criteria had been prescribed in 1995 by the American Academy of Otolaryngology-Head and Neck Surgery were used. Forty patients were tested a caloric response before and after the chemical labyrinthectomy. We analyzed the vertigo control rate, the change of the canal paresis and the change of hearing level. RESULTS:Vertigo was controlled in 90.8% of the 65 patients. Twelve patients of total 65 patients were decreased hearing level more than 10 dB after this procedure. Even though the severity of canal paresis increased, the hearing ability of most patients was unaffected. Some patients who had only slight canal paresis happened to suffer from hearing loss. CONCLUSION:There was no correlation between the change in the degree of canal paresis in the bithermal caloric test and the degree of the hearing change.
Caloric Tests* ; Ear, Inner ; Follow-Up Studies ; Hearing Loss* ; Hearing* ; Humans ; Medical Records ; Meniere Disease* ; Neck ; Paresis* ; Retrospective Studies ; Streptomycin ; Vertigo

No abstract available.
Animals ; Brain Stem* ; Brain* ; Electroshock* ; Hypothalamus* ; Mice*

No abstract available.
Glomerulonephritis*

BACKGROUND: Bentonite clay, which is a major component of mud pack, has been used for various purposes in cosmetics. Glycolic acid is known to be effective in the treatment of acne. Al-though those products are used widely, information on the mode of action and effects on the skin are little and controversial till now. OBJECTIVE: To investigate whether bentonite alone, or bentonite with glycolic acid in mixed formulation affect the stratum corneum leading to alteration on cutaneous barrier function and whether those products alter the lipid lamellae and desmosomes of corneocytes. MATERIALS AND METHODS: Mud pack-type ointment of bentonite, bentonite and 5% glycolic acid formulation, bentonite and 10% glycolic acid formulation were applied on the volar fore-arm of the five healthy men and flank skin of five 6-8 week old hairless mice. Transepidermal water loss and capacitance were measured. Electron microscopic examination after ruthenium tetroxide postfixation was performed on the flank skin of the mice. RESULTS: Transepidermal water loss(TEWL) increased immediately and normalized 4 to 6 hours later after removal of vapor permeable membrane in both mouse and human. Capacitance did not show any evidence of change in the water content of the stratum corneum. Electron microscopic examination revealed that lipid lamellae and desmosome of corneocytes were not de-graded, but lamellar body secretion and partially electron-lucent material was-increased in 10% glycolic acid and bentonite mixture-treated area. CONCLUSION: Barrier function of stratum corneum is not disturbed by bentonite and glycolic acid formulations at the concentration used. Barrier structures are not disrupted, but lamellar body secretion and partially electron-lucent material was increased by bentonite and glycolic acid formulations at higher concentration.
Acne Vulgaris ; Animals ; Bentonite* ; Desmosomes ; Humans ; Male ; Membranes ; Mice ; Mice, Hairless ; Mud Therapy ; Ruthenium ; Skin ; Water

No abstract available.
Esophageal Atresia* ; Tracheoesophageal Fistula*

No abstract available.
Cleidocranial Dysplasia*