1.Keberkesanan Antibiotik Titisan Mata Neomycin, Gentamycin & Ciprofloxacin Terhadap Sista Acanthamoeba spp.
Noradilah Samseh Abdullah ; Mohamed Kamel Abd Ghani ; Anisah Nordin ; Yusof Suboh ; Noraina Ab Rahim
Malaysian Journal of Health Sciences 2009;7(2):39-46
if not treated. This study was therefore performed to evaluate the effectiveness
of eyedrop antibiotics on eight Acanthamoeba spp. isolates, of which four
were clinical isolates and the remaining four from the environment. Three
different eyedrop antibiotics (neomycin, ciprofloxacin and gentamicin)
currently available in the market and ready for use were tested. Cyst
suspension from all strains were tested against eyedrop antibiotics,
respectively. After 48 hours of incubation period, the solutions were filtered
and the filtered membranes were put onto non-nutrient agar lawn with E. coli.
Bab 3 The plates were examined daily for Acanthamoeba trophozoites under inverted
microscope until day 14. Neomycin, ciprofloxacin and gentamicin were found
to be effective against Acanthamoeba spp. cysts for all test strains.
2. Impact of seasonality on the prevalence and risk factors of Giardia lamblia infections among the aborigines
Samseh Abdullah NORADILAH ; Norhayati MOKTAR ; Ii Li LEE ; Fatmah Md SALLEH ; Tengku Shahrul ANUAR ; Tengku Shahrul ANUAR
Asian Pacific Journal of Tropical Medicine 2019;12(7):315-320
Objective: To determine the prevalence and risk factors of Giardia (G.) lamblia infections among the aboriginal community during the wet and dry seasons. Methods: A total of 473 stool samples from the aborigines in Temerloh, Pahang, Malaysia were collected during wet (n=256) and dry seasons (n=217). Smear of all the PVA-preserved stool samples were subjected to Trichrome staining and microscopic examination under 1 000 x magnification (Nikon eclipse E100) for the detection of G. lamblia. Positivity was recorded based on the presence of G. lamblia in trophozoite and/or cyst forms. Results: The prevalence of giardiasis was 12.10% and 8.29% during the wet and dry season, respectively. Age of less or equal to 15 years old and presence of other family members with G. lamblia infection were found to be the significant risk factors to acquire G. lamblia infections during both seasons. Untreated water supply was the significant risk factor of giardiasis during the dry season. This study highlighted the possibility of anthroponotic transmission of G. lamblia during both seasons and waterborne transmission during the dry season in the aboriginal community. Conclusions: This study suggests that seasonal variation plays an important role in the prevalence and risk factor of G. lamblia infection in the aboriginal community. Therefore, close contact with Giardia-infected family members and water-related activities or usage of untreated water must be avoided to reduce the burden of G. lamblia infection in this community.