1.Clinical study on fetal heart rate and fetal movement reponse to music sound stimulation.
Korean Journal of Obstetrics and Gynecology 1993;36(7):1184-1189
No abstract available.
Female
;
Fetal Heart*
;
Fetal Movement*
;
Heart Rate, Fetal*
;
Music*
;
Pregnancy
2.Soft tissue tumor of the trunk and extremities.
Byeong Mun PARK ; Seok Beom LEE ; Dong Sam WOO
The Journal of the Korean Orthopaedic Association 1993;28(5):1783-1794
No abstract available.
Extremities*
3.Poland Syndrome
Sam Hyoun KI ; Young Bok CHUNG ; Eun Woo LEE
The Journal of the Korean Orthopaedic Association 1979;14(4):691-694
The combined congenital malformation of partiaI or complete absence of the pectoralis main muscle and webbing of the fingers, on the same side, was first described by Poland in 1841. The syndrome is not hereditary and is of unknown origin and is affects male more frequently than female. The clinical features are variable but always include congenital aplasia of the stemorostal head of the pectoralls major muscle and syndactyly. The syndectely should be treated by the age of one year and complened before the preschool age. A case of Poland's syndrome is presented with a brief review of literatures.
Female
;
Fingers
;
Head
;
Humans
;
Male
;
Poland Syndrome
;
Poland
;
Syndactyly
4.A Clinical Review in 31 Patients with Ulcerative Colitis.
Sam Beom LEE ; Byeong Ik JANG ; Heon Ju LEE ; Moon Kwan CHUNG ; Hyun Woo LEE
Korean Journal of Gastrointestinal Endoscopy 1991;11(2):355-361
Ulcerative colitis is diffuse inflammatory condition at mucosal lining of the colon & rectum and rare in Korea but there are no pathognomonic features or specific diagnostic tests. However, recently the diagnostic methods for ulcerative colitis are much developed and the incidence of ulcerative colitis is increased in Korea. Therefor, an analysis of 31 cases of ulcerative colitis which was diagnosed and treated in the department of the YeungNam University Hospital from May l983 to April 1991 was reviewed. The results were as following: 1) The sex distribution assumed a ratio of 1 to 2.1 and the age distribution was vqriable but the most prevalent age group was 5th decade(29.0%). 2) The most common clinical manifestations were abdominal pain & bloody diarrhea. 3) As to the extent of disease determined by the barium enema & endoscopy, rectum or rectosigmoid colon was involved in majority of the cases 22.6%, 41.9 (respectively). 4) Significant laboratory findings were elevated ESR, anemia, leukocytosis, hypoalbuminemia. 5) The endoscopic examination was performed in all 31 cases and showed sinificant findings such as hyperemia, mucosai edema, superficial ulceration & mucosal friability. 6) 23 of 26 cases treated by sulfasalazine medication showed improved, and 3 cases were improved by steriod medication and the surgical operation was indicated in 1 case.
Abdominal Pain
;
Age Distribution
;
Anemia
;
Barium
;
Colitis, Ulcerative*
;
Colon
;
Diagnostic Tests, Routine
;
Diarrhea
;
Edema
;
Endoscopy
;
Enema
;
Humans
;
Hyperemia
;
Hypoalbuminemia
;
Incidence
;
Korea
;
Leukocytosis
;
Rectum
;
Sex Distribution
;
Sulfasalazine
;
Ulcer*
5.Atrial Morphology Related to Secretory Function and Transport of Metabolites : I. Fenestrations of Basal Lamina in Rat Atrial Endocardium.
Moo Sam LEE ; Chang Ho SONG ; Hyung Tae KIM ; Gyung Woo JO ; Chang Hyun LEE
Korean Journal of Anatomy 1997;30(2):191-198
It was well known that atrial myocytes systhesize atrial natriuretic peptide[ANP], and secrete it into the atrial lumen through the atrial endocardium. But the mechanism for regulation of ANP secretion has not been clearly elucidated, because there was little information of the atrial morphology concerning basal lamina. Basal lamina is surmised as one of barriers that control the movement of ANP, a large molecule. This study was attempted to elucidate the morphological characteristics of basal lamina and connective tissue fibers of atrial endocardial layer by scanning electron microscopy. Basal lamina was exposed by removal of the overlying endothelium. This was achieved by using OsO4 maceration, immersion in aqueous boric acid or EDTA treatment. After removal of the endothelial cell, the specimens were exposed to ultrasonic vibration in case of need. The external surface of basal lamina showed a fairly smooth appearance on the whole, although a few irregular folds are often encountered. Fenestrations, 0.1-1 micrometer in diameter, were randomly observed on the basal lamina, and they were circular to oval in shape. Margin of fenestrations was somewhat distinct and some was divided into two parts by linear structures. The structural differences of fenestrations between right and left atria were not found. The fibroreticular lamina under the basal lamina was revealed by removal of the endothelial cells and their basal lamina. This layer was consisted of interwoven fine fibers. These fine fibers were repeatedly divided and fused, forming reticular network. Some fine fibers connected with basal lamina. Some connective tissue fibers below fibroreticular layer were collected into thick bundles running parallel to myocytes. Above results may serve as a basis for the physiological and morphological studies of atrium.
Animals
;
Atrial Natriuretic Factor
;
Basement Membrane*
;
Connective Tissue
;
Edetic Acid
;
Endocardium*
;
Endothelial Cells
;
Endothelium
;
Immersion
;
Microscopy, Electron, Scanning
;
Muscle Cells
;
Rats*
;
Running
;
Ultrasonics
;
Vibration
6.Pressor Effect of Intracerebroventricular Diphenhydramine and Ranitidine in Rabbits.
Han Ho CHO ; Soo Han KIM ; Sam Suk KANG ; Je Hyuk LEE ; Jung Hyun WOO
Journal of Korean Neurosurgical Society 1991;20(10-11):905-910
This study was undertaken to observe the effects of centrally administred antihistamines on the blood pressure. Diphenhydramine(DPH), a H1-receptor antagonist, and ranitidine(RAN), a H2-receptor antagonist were administered intracerebroventricularly(icv) on urethane-anesthetized rabbits. 1) Both DPH and RAN administered intraccebroventricularly increased blood pressure, however the intravenous(iv) adminstration of them did not affect blood pressure. The pressor response to icv DPH was dose-dependent, but that to icv RAN was not. 2) The pressor response to icv DPH(1mg) was either markedly attenuated or reversed to depressor response by the pretreatment with icv phentolamine(250,500ug), and iv chlorisondamine(0.1, 1mg/Kg) and iv phenoxybenzamine(1mg/Kg). In cord-sectioned rabbtis, icv RAN) 1mg) did not produce pressor response. 3) The pressor responsr to icv RAN(1mg) was not affected by the pretreatment with icv phentolamine(500ug), iv chlorisondamin(1mg/Kg) and iv phenoxybenzamine(1mg/Kg), and iv phenoxybenzamine(1mg/Kg). RAN also producted pressor response in cordsectioned rabbits. These results suggest that the pressor response to icv DPH is elecited by increasing peripheral sympathetic tone via the stimulation of central alpha-adrenoreceptors and the pressor response to icv RAN is produced by releasing some humoral facotr which can increase blood pressure.
Blood Pressure
;
Diphenhydramine*
;
Histamine Antagonists
;
Rabbits*
;
Ranitidine*
7.A clinicopathologic review of the early gastric adenocarcinoma (231 cases).
Byeung Ahm LEE ; Woo Young KIM ; Yoon Kyu PARK ; Eul Sam CHUNG
Journal of the Korean Cancer Association 1992;24(1):130-139
No abstract available.
Adenocarcinoma*
8.Clinical experience of atelectasis.
Sam Ryul RYU ; Byung Woo BAE ; Jong Won KIM ; Seong Kwang LEE ; Hwang Kiw CHUNG
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(11):1098-1106
No abstract available.
Pulmonary Atelectasis*
9.An Immunohistochemical study on distribution of natural killer(NK) cell in patients with cervical dysplasia and cervical cancer.
Kyu Wan LEE ; Hai Joong KIM ; Pyoung Sam KU ; Bom Woo YEOM
Korean Journal of Gynecologic Oncology and Colposcopy 1993;4(1):19-31
Natural Killer (NK) cells are a subpopulation of in vivo activated lymphocytes that display spontaneous cytotoxicity against a variety of targets as virus-infeeted, and transformed neoplastic cells, in major histocompatibility-unrestricted fashion. Depression of the NK aetivity in patients with advanced stages of various types of solid neopls,sms appears to be dependent upon the prcgressive growth and metastatic spread of the tumor. There are many reports that different distribution of subpopulations of lymphocytes in neopiastic tissue may influence the prognosis of the patients, In this study, we have performed immunohistochemieal study with Leu-7, MT1, LN2, and antilysozyrne antiserum on the tissue of uterine cervieal dysplasia and cancer to investigate the distribution of the NK cell, T cell, B cell, and macrophage. The results were as follows ; 1. The major subpopulation of lymphocytes infiltrating the lesion of intraepithelial neoplasia and squamous cell carcinama was T cell. 2. The number of infiltrated. lymphocytes was layer in the lesion of keratinzing type than in that of non keratinizing and small cell earcinorna of the uterine cervix. 3. NK cell was more frequently noted in the malignant lesion than the dysplastic lesion.
Cervix Uteri
;
Depression
;
Female
;
Humans
;
Killer Cells, Natural
;
Lymphocytes
;
Macrophages
;
Prognosis
;
Uterine Cervical Neoplasms*
10.The Expression and Correlation of Cyclin E, P21WAF1Protein and P53 Variant Protein in Colorectal Adenoma and Carcinoma.
Jong Woo KIM ; Hee Jung AHN ; Sung Woo CHOI ; Dae Ho AHN ; Jae Sam CHUNG ; Kyung Po LEE
Journal of the Korean Society of Coloproctology 1998;14(1):51-58
Cyclins are proteins that activate different cyclin-dependent kinases(CDKs) and promote the cell cycles. Their correlations with several human cancers have been identified. Cyclin E, as one of G1 cylins, produces DNA replication through the progression of cell cycle G1 --> S phase. In contrast, cyclin-dependent kinase inhibitors(CDKI) bound with cyclin E-cdk2 complex control the cell cycle and inhibit the cell proliferation. P21(WAF1) proteins, which are CDKIs, are transcripted by a p53 gene and participate in the cell cycle inhibition. Variant p53 proteins produced by a mutated p53 gene lose the ability to control of the cell cycle resulting in cell proliferation. This study is aimed to reveal the expressions of cyclin E, p21(WAF1) protein, p53 variant protein in colorectal adenomas and carcinomas, and also reveal their correlations in the process of carcinogenesis. Twenty-one colorectal adenomas or adenomatous polyps, and thirty colorectal carcinoma tissues were obtained by operative resections or endoscopic polypectomies. Immuno histochemical stains of the above-mentioned three proteins and a statistical analysis of their correlations were made. The results were as follows: 1. P21 proteins were expressed in the upper-one third layer of all normal colonic mucosa, but cyclin E and variant p53 protein were not identified. 2. Cyclin E was expressed in 23.8% of adenomas and 76.7% of carcinomas. Variant p53 protein was expressed in 71.4% of adenomas and 83.3% in carcinomas. The degree of positivity of variant p53 expression was correlated with cancer staging. P21 protein was expressed in all adenomas, similar to normal mucosa, but was not expressed in 43.3% of carcinomas. 3. Expression of cyclin E was increased as to the positivity of variant p53 proteins but the correlations of p21 proteins and cyclin E, and p21 proteins and variant p53 proteins were not identified. Cancer staging was not correlated with the expressions of the three proteins. In conclusion, it can be thought that the overexpression of cyclin E and variant p53 proteins, and the loss of p21 proteins are related with the colorectal carcinogenesis. We can also identify the relationship of cyclin E and variant p53 proteins.
Adenoma*
;
Adenomatous Polyps
;
Carcinogenesis
;
Cell Cycle
;
Cell Proliferation
;
Colon
;
Colorectal Neoplasms
;
Coloring Agents
;
Cyclin E*
;
Cyclins*
;
DNA Replication
;
Genes, p53
;
Humans
;
Mucous Membrane
;
Neoplasm Staging
;
Phosphotransferases
;
S Phase