1.Prevalence of bony septa, antral pathology, and dimensions of the maxillary sinus from a sinus augmentation perspective: A retrospective cone-beam computed tomography study.
Aditya TADINADA ; Elnaz JALALI ; Wesam AL-SALMAN ; Shantanu JAMBHEKAR ; Bina KATECHIA ; Khalid ALMAS
Imaging Science in Dentistry 2016;46(2):109-115
PURPOSE: Sinus elevation procedures have become a routine and reliable way to gain bone volume in the edentulous maxilla for dental implant placement. Presence of bony septations and pathology in the maxillary sinus often cause complications leading to graft or implant failure or both. The aim of this study was to retrospectively evaluate the prevalence of pathology, direction of the septa, and sinus width measured at 2 mm, 5 mm, and 10 mm from the sinus floor in maxillary sinuses using cone-beam computed tomography (CBCT). MATERIALS AND METHODS: Seventy-two sinuses from 36 random preoperative CBCT scans referred for implant therapy were retrospectively evaluated for the number, prevalence, and direction of bony septations and presence of pathology. Width of the sinus was also measured at 2 mm, 5 mm, and 10 mm from the sinus floor to account for the amount of bone available for implant placement. RESULTS: Maxillary sinus septa were found in 59.7%. Presence of a single septum was noted in 20 sinuses (27.7%), followed by two septa in 17 sinuses. The most common direction of the septum was the transverse direction. Retention pseudocyst and mucosal thickening were the most commonly seen abnormality/pathology. CONCLUSION: Based on the high prevalence of septa and sinus pathology in this sample, a preoperative CBCT scan might be helpful in minimizing complications during sinus augmentation procedures for dental implant therapy.
Cone-Beam Computed Tomography*
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Dental Implants
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Maxilla
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Maxillary Sinus*
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Pathology*
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Prevalence*
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Retrospective Studies*
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Transplants
2.Defining Coronary Artery Perforation with Ultrasound Contrast Agent
Young Jin YOUN ; Salman KHALID ; Michael AZRIN ; Juyong LEE
Korean Circulation Journal 2018;48(11):1028-1029
No abstract available.
Coronary Vessels
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Ultrasonography
4.Quantitative estimation of hesperidin by HPTLC in different varieties of citrus peels.
Prawez ALAM ; Aftab ALAM ; Md Khalid ANWER ; Saleh I ALQASOUMI
Asian Pacific Journal of Tropical Biomedicine 2014;4(4):262-266
OBJECTIVETo develop a simple, selective, sensitive and accurate high-performance thin layer chromatography (HPTLC) method to determine the quantity of hesperidin in different varieties of citrus fruits.
METHODSThe method was carried out in aluminum-backed silica gel 60 F254 plates with ethyl acetate-methanol-water 15:3:2 (%, v/v) as mobile phase.
RESULTSA compact band was obtained for hesperidin at Rf value of (0.40±0.04). The calibration plot was linear in the range of 100-800 ng/spot of hesperidin and the correlation coefficient of 0.998 6 was indicative of good linear dependence of peak area on concentration. Limit of detection (8.87 ng/spot), limit of quantification (23.21 ng/spot), accuracy (less than 2%) and recovery (ranging from 98.55-99.38) were found satisfactory.
CONCLUSIONSThe method developed can be used for routine analysis of hesperidin in crude drug as well as in herbal and pharmaceutical dosage form containing citrus fruits as an ingredient.
5.Molecular differentiation of coagulase-positive staphylococcal isolates carrying mecA- and PVL-encoding genes among healthy males
Ahmed Medhat Hanafy ; Khalid Rashad Al-Jabri ; Riyad Ali Al-Ahmadi ; Ahmed Mubrik Al-Matrafi
Malaysian Journal of Microbiology 2024;20(no.1):100-111
Aims:
This study was aimed to monitor the asymptomatic carriage of coagulase-positive staphylococcal bacteria among university male students and detect the prevalence of virulence marker genes that encode methicillin resistance (mecA) and Panton-Valentine leukocidin (PVL) toxin among the isolates.
Methodology and results:
Single nasal swaps were collected from 144 participating students who resided at four different locations within Al-Madinah city. A total of 112 Gram-positive staphylococcal isolates were recovered from the 144 participants (carriage rate of 77.8%). Coagulase-positive staphylococci were differentiated using duplex PCR amplification of the 16S rRNA and nuc genes and accounted for 30 isolates (carriage rate of 20.8%). These isolates were most prevalent in the northern and southern parts of Al-Madinah city, while the lowest numbers of isolates were detected in students of the eastern part. Coagulase-positive isolates were further phenotypically characterized for methicillin resistance by the disc diffusion method. Uniplex PCR assays were conducted to screen for mecA- and PVL toxin-encoding genes. The mecA gene was amplified from all 15 (50%) methicillin-resistant coagulase-positive isolates, while the PVL toxin-encoding gene was detected in 19 isolates (63.3%), 10 (33.3%) of which contained the mecA gene. Lastly, PCR amplification of the NRPS gene from coagulase-positive isolates revealed the absence of Staphylococcus argenteus, the recently discovered genetically divergent lineage of Staphylococcus aureus.
Conclusion, significance and impact of study
An elevated prevalence of coagulase-positive isolates harboring mecA and PVL virulence genes was observed compared with previous investigations. This poses a potential threat if they spread among the population, resulting in outbreaks of community-acquired infections.
6.Susceptibility Profiles of Bacterial Pathogens Causing Community-Acquired Urinary Tract Infections
Salman Sahab Atshan ; Zohier B Salah ; Khalid Jameel Kadhim Al-Zihirye ; Alreshidi Mateg Alif ; Rukman Awang Hamat
Malaysian Journal of Medicine and Health Sciences 2021;17(No.4):3-7
Introduction: Uncontrolled empirical treatment of urinary tract infections (UTIs) has negative aspect on predicting
the emergence of antimicrobial resistance and knowledge of those patterns has become extremely important
from time to time. Therefore, the aim of the present study was to check the prevalence and resistance patterns of
uropathogens in the community acquired UTIs. Methods: A total of 7132 urine samples were combined from male
3131 (43.9%) and female 4001 (56.1%) outpatients suspected of having UTIs, respectively over a three-year period
and cultured on routine culture media. The bacteria have been identified using basic biochemical tests, and sensitivity
to various antibiotics was determined by the method of disk diffusion. Results: Of 7132 urine samples 797
(11.2%) yielded significant uropathogens. Among the bacterial species, Escherichia coli was the major causative
agent of UTIs for both gender (63.7%), followed by Klebsiella spp (20.8%), Enterococcus faecalis (5.3%), Pseudomonas
spp (4.1%), Proteus spp (3.1%), Enterobacter spp (1.5%), Candida albicans (0.6%), Staphylococcus saprophyticus
(0.5%), Providencia spp (0.1%) and Staphylococcus aureus (0.1%). The antibacterial sensitivity testing
for E. coli, to commonly used antibiotics were showed variable resistant as follows: Ampicilln (78%), Amoxicillin
(71%), trimethoprim sulfamethoxazole (42%), Amox/clav. (14%) gentamicin (20%), nitrofurantoin (11%), nalidixic
acid (22%), ciprofloxacin (20%), Imipenem (16%),Ceftazidim (26%),Cefotaxim (25%),Ceftriaxon (21%),Cefuroxim
(33%). Conclusions: The findings showed that antimicrobial resistance patterns of uropathogens in variable, and
continuous monitoring of resistance patterns by using of antibiotic susceptibility testing in the laboratory is the most
appropriate to treat UTIs rather than the choice of UTIs empirical treatment.