1.Effect of Colcemid on Frequency and Direction of Ciliary Beat in Newt Lung.
Korean Journal of Physical Anthropology 1997;10(2):265-272
No abstract available.
Demecolcine*
;
Lung*
;
Salamandridae*
2.Effect of Colcemid on Distribution and Beat Direction of Cilia from Ciliated Cell of Newt Lung.
Korean Journal of Physical Anthropology 1998;11(2):299-306
No abstract available.
Cilia*
;
Demecolcine*
;
Lung*
;
Salamandridae*
3.Progress of cellular dedifferentiation research.
Hu-xian LIU ; Da-hai HU ; Chi-yu JIA ; Xiao-bing FU
Chinese Journal of Traumatology 2006;9(5):308-315
Differentiation, the stepwise specialization of cells, and transdifferentiation, the apparent switching of one cell type into another, capture much of the stem cell spotlight. But dedifferentiation, the developmental reversal of a cell before it reinvents itself, is an important process too. In multicellular organisms, cellular dedifferentiation is the major process underlying totipotency, regeneration and formation of new stem cell lineages. In humans, dedifferentiation is often associated with carcinogenesis. The study of cellular dedifferentiation in animals, particularly early events related to cell fate-switch and determination, is limited by the lack of a suitable, convenient experimental system. The classic example of dedifferentiation is limb and tail regeneration in urodele amphibians, such as salamanders. Recently, several investigators have shown that certain mammalian cell types can be induced to dedifferentiate to progenitor cells when stimulated with the appropriate signals or materials. These discoveries open the possibility that researchers might enhance the endogenous regenerative capacity of mammals by inducing cellular dedifferentiation in vivo.
Animals
;
Cell Differentiation
;
Cells, Cultured
;
Epidermal Growth Factor
;
physiology
;
Humans
;
Regeneration
;
Salamandridae
;
physiology
;
Serum
;
physiology
;
Thrombin
;
pharmacology