Objective To analyze the research status of domestic adverse nursing events and explore the hotpots in this field.Methods The research papers about adverse nursing events were searched in 2006—2016 for bibliometric study with the use of NoteExpress reference management software,literature metrology method (Bicomb 2.0 and Ucinet) and social network analysis method (NetDraw) based on CNKI and Wanfang Data knowledge service platform.Results A total of 5384 literatures were retrieved,and the total amount of literatures presented the increasing trend. We selected 11 peer reviewed journals including The Chinese and foreigh health abstract,Guide of China Medicine,Medical Information,etc.,and 28 high frequency key words like "safety management","nursing administration","nursing strategy",etc.. A total of 11 main research institutions included the Tenth People′s Hospital of Tongji University,the People′s Hospital of China Three Gorges University,Hangzhou First People′s Hospital,etc.. After the creation of network relationship picture,the hotspots were found out as follows:the causes analysis of clinical nursing adverse events and countermeasures research;prevent application research of the method of nursing adverse events;nursing safety management related research.Conclusions The research of adverse nursing events has developed quickly from 2010,and now has been concerned widely by domestic scholars,but dispersed geographical distribution and institutions, and high-level journals appear rarely.

Objective To analyze the research status of infants' complementary feeding and to summarize the research hotspots in this field.Methods Literature related to infants' complementary feeding was retrieved published in CNKI and WanFang date knowledge service platform from database created to May 2017. The method of bibliometrics and social network analysis were used to analyze these articles retrieved in publishing year, agencies, journals.Results A total of 1595 articles were searched publishing in 477 periodicals. The quantity of literature showed an increasing trend. There were 30 high-frequency keywords such as complementary feeding, breast feeding, growth and development as well as iron-deficiency anemia. A total of 10 major research institutions were included, for example, the Chinese Center for Disease Control and Prevention, Chinese Academy of Preventive Medicine and Sichuan University.Conclusions The current research hotspots focus on the effects of complementary feeding on infants' growth and development as well as nutrition, investigation analysis on infants' complementary feeding in the countryside, correlation analysis between complementary feeding and iron-deficiency anemia. Various research methods should be taken to carry studies related to knowledge on complementary feeding for infants' parents and behavior on complementary feeding.

Objective:To explore the research hotspots and development trends in the field of domestic disinfection supply in the past 10 years.Methods:We systematically searched the article in the field of disinfection supply included in the core journal database of China National Knowledge Infrastructure (CNKI) . The search subject was "disinfection supply" and "Supply Room", and the search time limit was from January 1, 2011 to September 1, 2021. The CiteSpace software was used to conduct keyword co-occurrence, keyword clustering, time-line map and keyword emergence analysis, and explore the research hotspots and development trends in the field of disinfection supply.Results:A total of 1 126 articles were retrieved. The bibliometric analysis showed that the domestic research in the field of disinfection supply in the past 10 years mainly focused on 10 aspects. Cleaning quality, disinfection and sterilization quality control, and nosocomial infection in Central Sterile Supply Department were still current research hotspots. The prevention and control of the COVID-19 epidemic was the focus of research in 2020 and 2021.Conclusions:The overall number of publications in the field of disinfection supply tends to be stable, and the prevention and control of nosocomial infection has been the focus of researchers in the past 10 years. It is recommended that future researchers strengthen multi-center cooperation and conduct experimental research and qualitative research on practitioners in the field of disinfection supply.

Objective:To analyze the characteristics of clinical distribution and change of aeroallergens in children with allergic diseases from 2015 to 2020.Methods:Children who visited Capital Institute of Pediatrics affiliated Children′s Hospital, suspected of allergic diseases and received serum aeroallergens specific immunoglobulin E (sIgE) test were retrospectively enrolled (1 to 14 years old). sIgE was detected by Phadia1000 system with radioallergosorbent test fluorescent enzyme-linked immunoassay. The characteristics and change of the aeroallergens among the 6 years was analyzed. Enumeration data were expressed by percentage and categorical variables were compared by the independent samples t-test and Pearson χ 2 test. Results:In total 4 608 tests (4 575 patients) of children were enrolled, the average age was (5.4±2.9) years old, with the median age of 5.0 years old. 3 176 were boys (68.9%), and 1 432 were girls (31.1%). 4 294 children were from the north of China (93.2%), 295 children were from the south of China (6.4%), and 19 children were from unknown regions (0.4%). In total the most common aeroallergen was mold mixture (1 956/4 457 tests, 43.9%) and Alternaria alternata (276/630 tests, 43.8%), followed by Artemisia (300/889 tests, 33.7%), Humulus scandens (12/38 tests, 31.6%) and grass mixture (909/2 874 tests, 31.6%). Among the 6 years, mold, grass pollen and tree pollen sensitization increased, and mold [38/130 (29.2%) vs 1 574/3 233 (48.7%)], grass pollen [11/77 (14.3%) vs 1 069/3 072 (34.8%)] increased significantly (χ 2 was 18.953 and 49.559, respectively, P=0.000). Positive rate of tree pollen increased [1/10 (10.0%) vs 516/2 122 (24.3%)], but did not have statistical significance (χ2=1.111, P=0.292). Dust mite [36/146 (24.7%) vs 321/1 408 (22.8%)] and hair of pets [7/33 (21.2%) vs 321/1 408 (17.1%)] sensitization didn′t change greatly (χ 2 =0.258, P =0.611; χ 2 =0.379, P =0.538). In 2015, the most common aeroallergens was mold (38/130, 29.2%), followed by dust mite (36/146, 24.7%), while in 2020, the most common aeroallergens was still mold (1 574/3 233, 48.7%), with grass pollen (1 069/3 072, 34.8%) and tree pollen (516/2 122, 24.3%) ranked after. Conclusion:Mold might be the most common aeroallergens in allergic children in Beijing area. With time went on, dust mite was gradually exceeded by grass pollen and tree pollen.

Objective:To analyze the characteristics of clinical distribution and change of aeroallergens in children with allergic diseases from 2015 to 2020.Methods:Children who visited Capital Institute of Pediatrics affiliated Children′s Hospital, suspected of allergic diseases and received serum aeroallergens specific immunoglobulin E (sIgE) test were retrospectively enrolled (1 to 14 years old). sIgE was detected by Phadia1000 system with radioallergosorbent test fluorescent enzyme-linked immunoassay. The characteristics and change of the aeroallergens among the 6 years was analyzed. Enumeration data were expressed by percentage and categorical variables were compared by the independent samples t-test and Pearson χ 2 test. Results:In total 4 608 tests (4 575 patients) of children were enrolled, the average age was (5.4±2.9) years old, with the median age of 5.0 years old. 3 176 were boys (68.9%), and 1 432 were girls (31.1%). 4 294 children were from the north of China (93.2%), 295 children were from the south of China (6.4%), and 19 children were from unknown regions (0.4%). In total the most common aeroallergen was mold mixture (1 956/4 457 tests, 43.9%) and Alternaria alternata (276/630 tests, 43.8%), followed by Artemisia (300/889 tests, 33.7%), Humulus scandens (12/38 tests, 31.6%) and grass mixture (909/2 874 tests, 31.6%). Among the 6 years, mold, grass pollen and tree pollen sensitization increased, and mold [38/130 (29.2%) vs 1 574/3 233 (48.7%)], grass pollen [11/77 (14.3%) vs 1 069/3 072 (34.8%)] increased significantly (χ 2 was 18.953 and 49.559, respectively, P=0.000). Positive rate of tree pollen increased [1/10 (10.0%) vs 516/2 122 (24.3%)], but did not have statistical significance (χ2=1.111, P=0.292). Dust mite [36/146 (24.7%) vs 321/1 408 (22.8%)] and hair of pets [7/33 (21.2%) vs 321/1 408 (17.1%)] sensitization didn′t change greatly (χ 2 =0.258, P =0.611; χ 2 =0.379, P =0.538). In 2015, the most common aeroallergens was mold (38/130, 29.2%), followed by dust mite (36/146, 24.7%), while in 2020, the most common aeroallergens was still mold (1 574/3 233, 48.7%), with grass pollen (1 069/3 072, 34.8%) and tree pollen (516/2 122, 24.3%) ranked after. Conclusion:Mold might be the most common aeroallergens in allergic children in Beijing area. With time went on, dust mite was gradually exceeded by grass pollen and tree pollen.