Objective:To explore the effect of Teach-Back model on oral health behavior among the middle-aged and aged.Methods:From March 2017 to June 2018, 150 middle-aged and elderly patients undergoing oral examinations from the Department of Preventive Dentistry, Hospital of Stomatology, Sun Yat-sen University were selected as the survey subject by convenience sampling. Patients were divided into experimental group ( n=70) and control group ( n=80) . Control group was given regular oral health guidance, and experimental group implemented Teach-Back nursing care on the basis of control group. After 6 months of intervention, we compared the cognition of periodontal disease, oral health behavior, and periodontal health status of middle-aged and elderly patients between two groups. Results:After 6 months of intervention, the scores of daily oral hygiene habits, periodontal disease cognition and periodontal disease treatment behavior of experimental group were higher than those of control group, and the differences were statistically significant ( P<0.05) . The Debris Index-Simplified (DI-S) , Calculus Index-Simplified (CI-S) , Gingival Index (GI) , Bleeing Index (BI) and Depth of Periodontal Pocket (PD) of experimental group were lower than those of control group with statistical differences ( P<0.05) . Conclusions:Middle-aged and elderly people have poor periodontal disease cognition and need nursing intervention. Teach-Back model can improve the daily oral hygiene habits of middle-aged and elderly patients, improve their correct understanding of periodontal disease, and improve their oral health behavior and quality of life.