1.Knowledge and Attitude of Women Regarding the Human Papillomavirus (HPV) Infection, Its Relationship to Cervical Cancer and Prevention Methods
Farah Farzaneh ; Hamidreza Esmaeilnia Shirvani ; Esmat Barouti ; Saghar Salehpour ; Nahid Khodakarami ; Kamyab Alizadeh
The Medical Journal of Malaysia 2011;66(5):468-473
This study aimed to determine knowledge and attitude of
women to HPV and its association with cervical cancer and
prevention methods. In a cross-sectional study, 500 women,
aged between 20 and 50 presenting to local health centers
in Tehran, were asked about demographic factors and
questioned about cervical cancer, HPV, and prevention
methods. Responses were tabulated and summarized.
Although knowledge of HPV, its relation to cervical cancer
and prevention methods among Iranian women is not
enough, their attitude towards education in this regards is
extremely high. The results reflect the need of advertising
and educational programs for public about HPV prevention
methods, to reduce the prevalence of this infection and its
severe consequences.
2.Effect of autologous platelet-rich plasma for treatment of recurrent pregnancy loss: a randomized controlled trial
Leila NAZARI ; Saghar SALEHPOUR ; Sedighe HOSSEINI ; Teibeh HASHEMI ; Nasrin BORUMANDNIA ; Elham AZIZI
Obstetrics & Gynecology Science 2022;65(3):266-272
Objective:
Recurrent pregnancy loss (RPL) is a fertility problem for which no exact mechanism of abortion or efficient treatment has been described. This study was conducted between 2018 and 2019 to investigate the effectiveness of autologous platelet-rich plasma (PRP) in improving the live birth rate of women with RPL who required in vitro fertilization (IVF).
Methods:
A total of 63 patients with at least two previous pregnancy losses and no specific cause detected for the RPL were included and randomly assigned into two groups (PRP and control). Intrauterine infusion of 0.5 mL of autologous PRP was performed 48 hours before embryo transfer in the PRP group. Women in the control group received standard treatment.
Results:
Forty patients completed the study. The baseline and cycle characteristics of the participants did not differ significantly between the PRP and control groups. The clinical pregnancy rate was higher in the PRP group (35% vs. 20%, P=0.288). The live birth rate was 15% in the PRP group, but no live births were recorded in the control group (P=0.231).
Conclusion
This is the first study to show that intrauterine infusion of PRP in patients with RPL who undergo IVF may increase the chance of live birth.
3.Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection.
Mohammad Hassan HEIDARI ; Marefat Ghaffari NOVIN ; Farzaneh AHMADI ; Mehran KHORSHID ; Tohid NAJAFI ; Aidin MOLOUKI ; Saghar SALEHPOUR ; Mojgan BANDEHPOUR ; Matineh HEIDARI ; Eimi SATO
Anatomy & Cell Biology 2011;44(4):331-336
Non-invasive methods are normally preferred to conventional invasive methods when selecting suitable embryos to improve pregnancy rates after assisted reproduction techniques. One of the most recognized non-invasive methods is to examine the supernatants of embryo culture media. Soluble human leukocyte antigen, class I, G (sHLA-G) antigen is a non-classical class I molecule that has been widely considered as a marker of pregnancy failure or implantation success. In the current study of some Iranian patients, we examined the concentration of sHLA-G at different time points after intracytoplasmic sperm injection and compared the rates to the morphology and quality of the selected embryos. We showed that the concentration of sHLA-G increases over time in high-quality embryos. We conclude that there is a positive relationship between morphology, quality, and sHLA-G concentration. We suggest that this relationship can be used to increase the chance of a successful pregnancy.
Culture Media
;
Embryonic Structures
;
HLA-G Antigens
;
Humans
;
Leukocytes
;
Pregnancy
;
Pregnancy Rate
;
Reproductive Techniques
;
Reproductive Techniques, Assisted
;
Sperm Injections, Intracytoplasmic