Philadelphia chromosome-positive acute myeloid leukemia (Ph+AML) is a rare disease characterized by a poor prognosis with resistance to standard chemotherapy. We report a patient with Ph+AML with a minor BCR-ABL-positive mRNA transcript who achieved a hematologic, cytogenetic, and major molecular complete response after cytarabine-based chemotherapy followed by imatinib. After more than 6 months of continuous imatinib therapy, the patient is in continuous complete remission. Our results show that imatinib mesylate is effective in treating Ph+AML.
Benzamides ; Cytogenetics ; Humans ; Leukemia ; Leukemia, Myeloid, Acute ; Mesylates ; Philadelphia ; Philadelphia Chromosome ; Piperazines ; Prognosis ; Pyrimidines ; Rare Diseases ; RNA, Messenger ; Imatinib Mesylate

PURPOSE: The study was done to examine undergraduate student' suicidal ideation and to identify influences of individual characteristics including psychological resilience and self-control on suicidal ideation. METHODS: Data were collected from 400 students in 11 universities in D city from May 1 to June 30, 2011. Data were analyzed with t-test, one-way ANOVA and Pearson' correlation using SPSS 19.0. RESULTS: Of the students, 11.3% reported suicidal ideation levels higher than average. Woman students and those with high career anxiety, perceived poor health condition and bad relationships showed higher points on suicidal ideation. Suicidal ideation was also negatively correlated with psychological resilience and self-control. CONCLUSION: Over 10.0% of students need careful attention on suicidal ideation, especially counselling service related to suicide prevention for students with poor health, high career anxiety, and bad relationships. Various programs should be developed to promote psychological resilience to improve health and relationships, as well as job guidance for students. It is also suggested the students' experiences be examined to determine how they overcame suicidal ideation.
Anxiety ; Female ; Humans ; Resilience, Psychological* ; Suicidal Ideation* ; Suicide