No abstract available.
Animals ; Embryonic Structures* ; Female ; Follicular Fluid* ; Humans* ; Mice*

No Abstract Available.
Hepacivirus* ; Hepatitis C* ; Hepatitis* ; Humans ; Polymerase Chain Reaction*

No Abstract Available.
Hepacivirus* ; Hepatitis C* ; Hepatitis* ; Humans ; Polymerase Chain Reaction*

We report herein a case of clear cell hidradenoma in a 65-year-old man, who had a 8-month history of a asymptomatic, smooth-surfaced, round, blue tumor mass with cystic grape-like nature on the left upper chest, measuring 2.0 x 2.0 x 1.5cm in size. A histopathological examination revealed tubular and cystic structures within the intradermal tumor composed of predominant fusiform cells and clear cells, and some transitional cells. The patient remained free of recurrence for a period of one-year follow-up after the excision.
Acrospiroma* ; Aged ; Follow-Up Studies ; Humans ; Recurrence ; Thorax

Occupational stress is associated with increased risk of cardiovascular disease (CVD), while cardiorespiratory fitness (CRF) is associated with decreased risk of CVD. We tested the hypothesis that high occupational stress would be associated with increased cardiovascular risk profiles, but CRF may attenuate this association. We conducted a cross-sectional analysis in 70 healthy office workers (male, 28; female, 42; mean age, 38±8 years). Occupational stress was assessed using a validated self-reported questionnaire. Total CVD risk score (sum of z-standardized residuals) was calculated by blood pressure, body mass index, lipid profiles and glucose. CRF was estimated by predicted equation during maximal treadmill exercise test. The results showed that an interpersonal conflict as an index of occupational stress was positively correlated with cardiovascular risk score (r=0.43, p<0.05). In contrast, Higher CRF was associated with lower occupational climate (r=−0.25, p<0.05) and total occupational stress score (r=−0.29, p<0.05). The total CVD risk score was similar between group with high stress but high fitness and group with low stress and high fitness (p>0.05). Furthermore, Participants with high stress but high CRF had lower cardiovascular risk score than those with high stress but low CRF (p<0.05). In conclusion, occupational stress is associated with an increased CVD risk, but CRF attenuated this association in office worker with increased occupational stress.
Blood Pressure ; Body Mass Index ; Cardiovascular Diseases* ; Climate ; Cross-Sectional Studies ; Exercise Test ; Female ; Glucose ; Humans ; Risk Factors*

PURPOSE: Remote ischemic preconditioning (RIPC), induced by repeated bouts of ischemia followed by reperfusion of the arm or leg is a noninvasive strategy to protect a target organ against oxidative stress and injury caused by ischemia and reperfusion. Interestingly, recent evidence suggests that RIPC may also improve exercise performance by increasing maximal oxygen consumption, but such finding remain equivocal. As such, the purpose of the study was to examine the effect of RIPC on exercise performance in healthy individuals. METHODS: In a randomized cross-over design, 17 healthy male participants (age, 23±3 years) were exposed to either a sham control (six cycles of 5 minutes bilateral thigh cuff occlusion at 20 mm Hg) or RIPC (six cycles of 5 minutes bilateral thigh cuff occlusion at 180 mm Hg) an hour before a maximal exercise test. We measured maximal oxygen consumption, power output, heat rate, blood pressure, and blood lactate as exercise performance parameters during a maximal exercise test performed on an upright bicycle. RESULTS: Compared with the sham control, RIPC improved maximal oxygen consumption (7.4%, p=0.025) and maximal power output (11.5%, p=0.010), whereas other exercise performance parameters remained unchanged with RIPC (p>0.05). CONCLUSION: Taken together, the improvements in maximal oxygen consumption and maximal power output induced by RIPC may suggest that RIPC should be considered as a method for improving exercise performance.
Arm ; Blood Circulation ; Blood Pressure ; Cross-Over Studies ; Exercise Test ; Exercise Tolerance* ; Hot Temperature ; Humans ; Ischemia ; Ischemic Preconditioning* ; Lactic Acid ; Leg ; Male ; Methods ; Oxidative Stress ; Oxygen Consumption ; Reperfusion ; Thigh ; Young Adult*

Purpose: The purpose of the study was to examine whether a 7-day ischemic preconditioning (IPC) intervention would attenuate the prolonged sitting-induced lower limb vascular dysfunction in healthy men. Methods: In a randomized control trial, 12 healthy men (age, 24.9±2.6 years) were assigned to either a 7-day IPC intervention (6×5 minutes of bilateral thigh cuff occlusions at 200 mm Hg) or a sham control group (6×5 minutes of bilateral thigh cuff occlusions at 20 mm Hg). After the 7-day IPC intervention, the participants underwent a 4-hour prolonged sitting. We measured blood pressure, central blood pressure, and superficial femoral artery flow-mediated dilation at baseline (before intervention), pre-sitting (after intervention), post-2-hour sitting, and post-4-hour sitting. Results: During the 4-hour sitting time, blood pressure and central blood pressure did not significantly change from baseline in any group. However, superficial femoral artery flow-mediated dilation decreased from baseline more so in the sham control group (5.2±1.9 to 1.7±1.2) compared with the IPC group (4.6±2.2 to 3.1±1.5, p=0.015 for interaction). Conclusion These findings demonstrate that a 7-day IPC protected against lower limb vascular dysfunction during prolonged sitting in healthy men.

Purpose: The purpose of this study was to determine whether ischemic preconditioning (IPC) improves lower limb isokinetic muscle function and blood lactate concentration. Methods: In a randomized, crossover study, 10 men, college baseball players, performed knee extension and flexion using an isokinetic dynamometer, preceded by either IPC of the right lower limb (3 repetitions of 2 minutes occlusion and 5 minutes reperfusion at 180 mm Hg) or a control intervention (at 20 mm Hg). Blood lactate concentration was examined from rest to recovery after exercise. Results: We found IPC possibly increased peak force and average power, but there is no significant difference.Also, blood lactate concentration was certainly lower at 3 minutes of recovery after IPC (p＜ 0.05) but there is no interaction effect. Conclusion As a result, IPC does not have any positive effects on isokinetic muscle function and blood lactate concentration of college baseball players.

Long COVID has emerged as a global medical challenge, characterized by persistent symptoms such as fatigue, dyspnea, and exercise intolerance following a coronavirus disease 19 (COVID-19) infection. The protracted nature of these symptoms necessitates the development of effective therapeutic approaches to alleviate the burden on individuals’ well-being and the healthcare system at large. While current pharmacological interventions offer limited efficacy, the exploration of alternative strategies becomes imperative. Exercise training has demonstrated promise in ameliorating long COVID symptoms, yet consensus regarding the optimal exercise modalities remains elusive. In light of this, the present review aims to elucidate the impact of exercise on long COVID symptoms and shed light on exercise prescriptions that have exhibited proven efficacy in the treatment and management of this syndrome.

No Abstract Available.
Histidine*