1.Clomerular deposition of fibrin(Ogen) in glomerulonephritis.
Dong Ho YANG ; Sae Yong HONG ; Chang Jin KIM
Korean Journal of Nephrology 1991;10(3):336-342
No abstract available.
Glomerulonephritis*
2.Prospective trial of lumbricus rubellus in patients with chronic renal insufficience.
Sae Yong HONG ; Dong Ho YANG ; Sun Yang PARK
Korean Journal of Nephrology 1992;11(4):411-416
No abstract available.
Humans
;
Oligochaeta*
;
Prospective Studies*
3.Idiopathic cyclic edema : clinical evaluation.
Mi Kyung CHA ; Dong Ho YANG ; Sae Yong HONG
Korean Journal of Nephrology 1993;12(3):426-432
No abstract available.
Edema*
4.Primary Carcinoma Arising in Vesical Diverticula.
Sae Yong CHANG ; Eun Kyung HONG ; Soo Eung CHAI ; Jung Dal LEE ; Tai Chin KIM
Korean Journal of Urology 1982;23(8):1205-1208
Primary carcinoma arising in the diverticular wall of the urinary bladder is the most serious complication. The clinical importance is that the carcinoma is difficult to diagnose early, widespread at diagnosis and has poor prognosis. Recently, vigilant studies including bladder mapping reveal premalignant changes and carcinoma in situ adjacent to carcinoma and suggest these premalignant changes evolve to flank carcinoma. For early detection and improving the prognosis, be required through cystoscopic examination including diverticular wall and multiple punch biopsies as well as consecutive urine cytologic examination. Author report two cases of primary carcinoma arising in bladder diverticulum. One revealed carcinoma in situ accompanied with adjacent atypical hyperplasia in diverticula mucosa incidentally found at the pathologic examination on the divertiuclectomy specimen. The other case showed invasive transitional cell carcinoma(Grade IV, Stage D) of diverticulum. The two cases described suggest that vesical diverticulum should be removed into to with a good amount of surrounding bladder wall.
Biopsy
;
Carcinoma in Situ
;
Diagnosis
;
Diverticulum*
;
Hyperplasia
;
Mucous Membrane
;
Prognosis
;
Urinary Bladder
5.Clinical Observation of Anticholinesterase-inhibitor Insecticides Poisoning.
Joo Ho HWANG ; Dong Ho YANG ; Sae Yong HONG
Korean Journal of Medicine 1998;55(2):149-157
BACKGROUND: Organophosphate and carbamate insecticides have been used extensively in agriculture resulting in serious increases in poisoning. Levels of poisoning by carbamates and organic phosphorus compounds and the severity of associated symptoms are dependent not only on the degree of reduction of acetylcholinesterase activity in the nervous system but also on the rate of inhibition and the type of inhibitive action. The most striking differences between the clinical effects of the two groups of compounds are the much more rapid and spontaneous recovery from poisoning by carbamates and the relatively large difference between the smallest dosage of any carbamate that will cause mild illness and the lethal dosage of the same compound. The purpose of this study is to compare the clinical characteristics of acute intoxication by organophosphate and carbamate insecticides. METHOD: We retrospectively analyzed the clinical characteristics of 41 patients poisoned with organophsphates and 12 patients poisoned with carbamates, who were admitted to the department of internal medicine, Soonchunhyang Chunan hospital from January 1995 to December 1996. RESULTS: 1) The most common organophosphate was EPN (9 cases) followed by Dichlorvos (7 cases). In the carbamates group, Carbofuran (5 cases) was the most common followed by Methomyl (3 cases).2) The main cause of poisoning was ingestion for the purpose of suicide in both groups.3) The severity of poisoning was more acute in the organophosphate group than in the carbamate group.4) Altered consciousness and respiratory depression occurred more frequently in the organophosphate group than in the carbamate group. Six cases out of the organophosphate group suffered from respiratory depression 24 hours to 96 hours after poisoning.5) The activity of serum cholinesterase showed no significant difference between poisoning with organophosphates and with carbamates.6) The mortality rate was 22% in organophosphate intoxication and 16.7% in carbamate intoxication. The most common complication of organophosphate and carbamate intoxication was aspiration pneumonia. CONCLUSION: Carbamate insecticides exhibited less toxicity than organophosphates.
Acetylcholinesterase
;
Agriculture
;
Carbamates
;
Carbofuran
;
Cholinesterases
;
Chungcheongnam-do
;
Consciousness
;
Dichlorvos
;
Eating
;
Humans
;
Insecticides*
;
Internal Medicine
;
Methomyl
;
Mortality
;
Nervous System
;
Organophosphates
;
Phosphorus Compounds
;
Pneumonia, Aspiration
;
Poisoning*
;
Respiratory Insufficiency
;
Retrospective Studies
;
Strikes, Employee
;
Suicide
6.Dialyzer Thrombogenicity and Heparinized.
Korean Journal of Nephrology 2003;22(4):337-339
No abstract available.
Heparin*
7.The survival rate and causes of death in patients with chronic renal failure on hemodialysis.
Won Suk CHOO ; Ki Woun KIM ; Dong Ho YANG ; Sae Yong HONG
Korean Journal of Nephrology 1992;11(1):56-61
No abstract available.
Cause of Death*
;
Humans
;
Kidney Failure, Chronic*
;
Renal Dialysis*
;
Survival Rate*
8.The Effects of Hantaan Virus on the Expression of Platelet Activating Factor Receptor and on the Activity of Platelet Activating Factor Acetylhydrolase.
Ji Young HWANG ; Jong Won PARK ; Sae Yong HONG ; Ho Sun PARK
Yeungnam University Journal of Medicine 2008;25(1):41-49
BACKGROUND: The central physiological derangement of hemorrhagic fever with renal syndrome (HFRS) caused by hantaan virus (HTNV) is a vascular dysfunction, manifested by hemorrhage, impaired vascular tone and increased vascular permeability. Platelet activating factor (PAF), whose actions are mediated through a specific receptor, is a potent bioactive lipid. PAF has diverse biological functions in the vascular system, such as increasing vascular permeability, adhesion of leukocytes to the endothelium and reduction of cardiac output, which result in hypotension and shock. The goal of the present study was to investigate whether PAF is involved in the pathogenesis of HFRS. For this purpose, we evaluated the effect of HTNV on the expression of PAF receptor (PAF-R) and on the activity of PAF-acetylhydrolase (PAF-AH) instead of PAF because PAF is rapidly degraded by PAF-AH in vivo. MATERIALS AND METHODS: To evaluate the expression of PAF-R, we performed reverse-transcription PCR, western blot and FACS analyses using HTNV-infected human umbilical vein endothelial cells (HUVECs) and non-infected (control) HUVECs. In addition, we measured the activity of plasma PAF-AH in HFRS patients and normal healthy persons. RESULTS: The mRNA and protein expression of PAF-R was increased in HTNV-infected HUVECs compared with control HUVECs at 2 and 3 days post-infection (d.p.i.). FACS analysis showed that HTNV induced the surface expression of PAF-R in HUVECs from 2 d.p.i. The activity of plasma PAF-AH was 2.5-fold lower in HFRS patients than in normal healthy persons. CONCLUSION: Increased PAF-R expression by HTNV might increase the responsiveness to PAF in endothelial cells. Reduced PAF-AH activity in the blood of HFRS patients might delay PAF degradation. These results suggest that changes in PAF-R and PAF-AH by HTNV might influence to PAF activity and might be involved in the vascular dysfunction of HFRS.
Blood Platelets
;
Blotting, Western
;
Capillary Permeability
;
Cardiac Output
;
Endothelial Cells
;
Endothelium
;
Hantaan virus
;
Hemorrhage
;
Hemorrhagic Fever with Renal Syndrome
;
Human Umbilical Vein Endothelial Cells
;
Humans
;
Hypotension
;
Leukocytes
;
Plasma
;
Platelet Activating Factor
;
Platelet Membrane Glycoproteins
;
Polymerase Chain Reaction
;
Receptors, G-Protein-Coupled
;
RNA, Messenger
;
Shock
9.Paraquat-Induced Pulmonary Lesions: HRCT Findings in Long-Term Follow-up: A Case Report.
Young Tong KIM ; Sae Yong HONG ; Il Young KIM
Journal of the Korean Radiological Society 1997;36(3):451-453
We illustrate serial HRCT findings over a 16-month period in a 35-year-old woman who had ingested paraquat. Initial areas of ground-glass opacity changed into areas of multiple air cysts on follow up scan obtained five months after ingestion. A further follow-up scan obtained 16 months after ingestion showed improvement, with increased lung volume and normalized lung architecture.
Adult
;
Eating
;
Female
;
Follow-Up Studies*
;
Humans
;
Lung
;
Paraquat
10.Paraquat-Induced Pulmonary Lesions: HRCT Findings in Long-Term Follow-up: A Case Report.
Young Tong KIM ; Sae Yong HONG ; Il Young KIM
Journal of the Korean Radiological Society 1997;36(3):451-453
We illustrate serial HRCT findings over a 16-month period in a 35-year-old woman who had ingested paraquat. Initial areas of ground-glass opacity changed into areas of multiple air cysts on follow up scan obtained five months after ingestion. A further follow-up scan obtained 16 months after ingestion showed improvement, with increased lung volume and normalized lung architecture.
Adult
;
Eating
;
Female
;
Follow-Up Studies*
;
Humans
;
Lung
;
Paraquat