1.A Case of Elephantiasis Neuromatosa.
Sae Hyun PYUN ; Dong Seok KIM ; Sang Won KIM
Korean Journal of Dermatology 1988;26(2):241-246
We report herein a case of elephantiasis neuromatosa seen in neurofibromatosis patient, who was a 33-year-old male and had been diagnosed at the age of 13. Since that time on, small nodule present on the mid-back area led to develop grotesquely large, dark-brown colored, flabby mass with thick verucoid skin change, measuring about 30 * 20cm in size. Histopathologic examination of excised mass demonstrated moderate hyperplasia of epidermis and typical neurofibroma findings with soft tissue and fibrous tissue overgrowth, but no atypical cells. The electron microscopic study showed many perineurial cells surrounded by the continuous bssal lamina of fibroblsst in the dermal lesion and numerous giant pigmented granules in melanocyte and basal keratinocyte in the cafe-au-lait spot.
Adult
;
Cafe-au-Lait Spots
;
Elephantiasis*
;
Epidermis
;
Humans
;
Hyperplasia
;
Keratinocytes
;
Male
;
Melanocytes
;
Neurofibroma
;
Neurofibromatoses
;
Skin
2.Epidemiologic Survey of the Serlogic Markers of Hepatitis B Virus and Serologic Tests for Syphilis in Institutionalized Persons.
Sae Hyun PYUN ; Kyung Jae CHUNG ; Sang Won KIM
Korean Journal of Dermatology 1988;26(4):482-488
To survey the seroprevalence of hepatit!s B virus(HBV) in relation to serologic tests for syphilis(STS), using VDRL and TPHA test, the tests were done in the seri of 1252 institutionalized persons, who lived in Taegu Hope Village for the poor or crippled, and 1831 controls, who had the regular routine physical examination from March to May, 1987. The positive rates nf HBsAg and anti-HBs were 11.7%(146) and 27.0%(338'). compared with 6.25%(ll) and 18.4%(337) in controls, respectively. The prevalence of HBV including HBsAg and anti-HBs was higher in institutionalized persons (38,7+i) than in controls(24.6%)(p<0.0001). The positive rate of STS was higher in institutionalized persons(7.5%) than in controls(2.9%)(p<0.0001). There was a tvend for a higher rate of seropositivity in women than in men of institution- alized persons in the both diseases. The prevalence of HBV among STS-positive cases wa.s 42.6%(40) of instituti- onalized persons and 26.4%(14) of controls, but not, statistically significant, the gre,ater part of them distributing in 4th and 5th decades. The positive rates of I-tBi.Ag in institutionalized persons was 45.5%(5) of STS-positive cases and 25. 9%,'35) of STS-negative cases. No correlation was found between the serologic ma kers of HBV and VDRL titration.
Daegu
;
Female
;
Hepatitis B Surface Antigens
;
Hepatitis B virus*
;
Hepatitis B*
;
Hepatitis*
;
Hope
;
Humans
;
Institutionalization*
;
Male
;
Physical Examination
;
Prevalence
;
Seroepidemiologic Studies
;
Serologic Tests*
;
Syphilis*
3.Disabling Pansclerotic Morphea.
Dong Seok KIM ; Sae Hyun PYUN ; Sang Won KIM
Korean Journal of Dermatology 1988;26(6):894-900
Disibling pansclerotic morphea, a severe form of generalized morphea, has a relentless clisabling course, producing marked contract,ion and joint deformity due to sclerosis of the skin and the deeper structures. We report herein an unusual case of morphea in a 25 year old male who had suffered from chronic recurrent ulceration with scar like sclerotic changes overlying limb folds, ankles, nape and abdomen since 4 years of age. The indurated lesions on the chest and abdomen were ivory colored, sclerotic guttae and plaques having a, violac ous border. At l4 years of age, the skin lesions were diagnostically ambiguous, wherea.s the immunologic results revealed a selective IgA deficiency with partial T lymphacyte inactivation. About 10 years later, the follow up visit showed this severe form of morphea over generalized area and disabling contractures of knees, elbows and alkles, but IgA value returned nearly to the nomal level.
Abdomen
;
Adult
;
Ankle
;
Cicatrix
;
Congenital Abnormalities
;
Contracture
;
Elbow
;
Extremities
;
Follow-Up Studies
;
Humans
;
IgA Deficiency
;
Immunoglobulin A
;
Joints
;
Knee
;
Male
;
Scleroderma, Localized*
;
Sclerosis
;
Skin
;
Thorax
;
Ulcer
4.Epidemiologic Study of Paederus Dermatitis Prevailing in the Midwest Area of Kyungpuk Province.
Jang Oh KIM ; Sang Won KIM ; Dong Seok KIM ; Sae Hyun PYUN
Korean Journal of Dermatology 1995;33(5):821-829
BACKGROUND: Paederus derriattis is a peculiar linear lesion caused by an insect belonging to genus Paederus, family Staptylinidae, order Coleoptera. The deliberate or accidental contact of crushed coelomic fluid of th insect, on the skin causes acute lesions due to a t.oxin(pederin) being released. OBJECTIVE: The study was nade in order to investigate an epidemic status of the peculiar der matitis and its causative agent of factor prevailing in the midwest area of Kyungpuk province. METHODS: We performed field approaches on 633 cases(M: 303, F: 330) including cases enrolled in a local clinic, teamiring up with a local skin clinician over the 3-month period of August November in 1994. RESULTS: 1. The captive insect causing the present dermatits, was identified as Paederus fuscipes(PF). The epidemic might be attributeid to the climatic conditions with higher temperature than usual during the period of July-eary September in the past year by 3-4degrees C as well as a lower relative humidity. The active temperature zone for PF was presumed to be about 15.5+1.2degrees C to 28.9+1.0degrees C 2. There was the highest p;evalence of 412 cases(65.1%) in early September, followed by mid September, late August, early October and mid August in a small number of cases in decreasing order. The cases were not found after mid October. 3. All age groups were evealy represented. The sex ratio was 1: 1.1 with little difference. The majority of cases lived in Kiriich on city(80.3%), with a lesser outbreak in the neighboring coun ties and Kumi city. 4. The preferred site was the mainly exposed area such as face, neck and extremities. The number of lesion was single(60%) and multiple(40%). The lesion showed a common linear con figuration and acute irritant contact dermatitis consistent with the histologic finding. CONCLUSION: The unusual wiather conditions and poor environmental hygiene help to develop an ecosystem breakdown, which, in turn, sometimes influences the innocuous insects life to be harm ful being on humans, as like outbreak of PF dermatitis.
Beetles
;
Dermatitis*
;
Dermatitis, Contact
;
Ecosystem
;
Epidemiologic Studies*
;
Extremities
;
Gyeongsangbuk-do
;
Humans
;
Humidity
;
Hygiene
;
Insects
;
Neck
;
Sex Ratio
;
Skin
5.A Case of Clear Cell Hidradenoma.
Kwang Young PARK ; Jae Kyung PARK ; Sang Won KIM ; Sae Hyun PYUN
Korean Journal of Dermatology 1990;28(5):651-655
We report herein a case of clear cell hidradenoma in a 65-year-old man, who had a 8-month history of a asymptomatic, smooth-surfaced, round, blue tumor mass with cystic grape-like nature on the left upper chest, measuring 2.0 x 2.0 x 1.5cm in size. A histopathological examination revealed tubular and cystic structures within the intradermal tumor composed of predominant fusiform cells and clear cells, and some transitional cells. The patient remained free of recurrence for a period of one-year follow-up after the excision.
Acrospiroma*
;
Aged
;
Follow-Up Studies
;
Humans
;
Recurrence
;
Thorax
6.A Case of Median Raphe Cysts and Canal of the Scrotum.
Jae Kyung PARK ; Sae Hyun PYUN ; Soo Chan KANG ; Sang Won KIM
Korean Journal of Dermatology 1989;27(3):334-337
We reported herein a case of median raphe cysts and canal of the scrotum. The 7-year-old patient had had the beaded cysts of 0.1 to 0.5cm in size slong a cord-like canal measuring about 8cm in the median raphe of the scrotum since the birth on. The cystic wall was unilocular and lined by pseudostratified columnar epitheliurn of one to four cells in thickness.
Child
;
Humans
;
Parturition
;
Scrotum*
7.A Case of Median Raphe Cysts and Canal of the Scrotum.
Jae Kyung PARK ; Sae Hyun PYUN ; Soo Chan KANG ; Sang Won KIM
Korean Journal of Dermatology 1989;27(3):334-337
We reported herein a case of median raphe cysts and canal of the scrotum. The 7-year-old patient had had the beaded cysts of 0.1 to 0.5cm in size slong a cord-like canal measuring about 8cm in the median raphe of the scrotum since the birth on. The cystic wall was unilocular and lined by pseudostratified columnar epitheliurn of one to four cells in thickness.
Child
;
Humans
;
Parturition
;
Scrotum*
8.Three Cases of Superficial Migratory Thrombophlebitis.
Jae Kyung PARK ; Sae Hyun PYUN ; Soo Chan KANG ; Sang Won KIM
Korean Journal of Dermatology 1989;27(5):626-632
We report herein three cases of superficial migratory thrornbophlebitis, who were all male, aged 33(Case 1), 49(Case 2), and 41(Case 3), respectively. Common to all three cases were the lesions which were multiple tender superfieial erythematous nodules, about 0.5 to 1.5cm in diameter, in cord-like indurations slong the superficial veins over the legs and feet. Histopathologically, the deep dermal veins commonly showed luminal occlusions by thrombi, and inflarnmstory infiltrates of a fairly large number of lyrnphohistiocytes and a few giant cells in their walls and surrounding tissues. Cases 1 and 2 were with idiopathic type, and Cage 3was associated with Buergers disease. The systemic therapy with dipyridamole, nicotinamide, aspirin and piraicam had been tried with unsatisfactory results.
Aspirin
;
Dipyridamole
;
Foot
;
Giant Cells
;
Humans
;
Leg
;
Male
;
Niacinamide
;
Phenobarbital
;
Thromboangiitis Obliterans
;
Thrombophlebitis*
;
Veins