Lichen nitidus is a comparatively rare, asymptomatic, chronic disease displaying small, sharpIy defined, fresh colored papules usually localized on the penis, arms and the abdomen. Waisman found immunoglobulin at the dermo-epidermaI junction in lichen planus, but not in lichen nitidus. This settled the argument whether lichen nitidus is a variant of lichen planus. A 11 year old healthy girI was brought to the clinic because of many flesh colored discrete papules on the cubital fossae and the anterior chest. The papules are skin colored. pinhead sized, round, and flat-topped The lesions appeared first at the age of 8 on the antecubital folds and in the following years, increased in number and extended slowly to the upper arms and the anteior chest.
Abdomen ; Arm ; Child ; Chronic Disease ; Humans ; Immunoglobulins ; Lichen Nitidus* ; Lichen Planus ; Lichens* ; Male ; Penis ; Skin ; Thorax

Fundamental pathologic cianges of secondary syphilid are said to be swelling and proliferation of endothelials and a predominantly parivascular infiltrates composed chiefly of lymphoid cells and plasma cells. But recentIy this theory has heen challenged. We present bistologic observation made on 10 patients who agreed to go through a biopsy, during 2 years period. from 1975 to l977. Male to female ratio was 9: 1 The age of patient ranged from 20 to 33, with a mean of 26. 8. The duration of lesion before the visit to the department ranged frorn 6 weeks to 20 weeks, with a mean of 11.9. The lesions in 2 were classified as macule, 3 as papule (1 as moist papule), and 5 as papulo-squamous lesions. The VDRL titer was higher in papular type. Dark fieId examination was performed on all patient and 6 showed positive result. The edidermal changes consist of hyperkeratosis (in 6 cases), parakeratosis (in 5), acanthosis (in 6), elongation of rete ridges (in 8) and exocytosis (in 3). The dermis showed mild to severe perivascular infiltration consist chiefly of lymphoid cells and histiocytic cells (in 10), plama cells (in 7), eosinophils (in 4), neutrophils (in 2), chromatophores (in 4), extra vasation of RBC (in 5), and dilated bload vessels endothelial swellings (in 8). Of particular interest was the finding that plasma cell infiltration is more pronounced at the lower portion of dermal infiltrate and in 3 cases plasma cell infiltration was totally absent. Vascular changes were seen in 8 cases.
Biopsy ; Chromatophores ; Dermis ; Eosinophils ; Exocytosis ; Female ; Humans ; Lymphocytes ; Male ; Neutrophils ; Parakeratosis ; Plasma Cells ; Syphilis, Cutaneous*

No abstract available.
Pneumothorax* ; Thorax*

No abstract available.
Hysterectomy* ; Venous Thrombosis*

The nevus spilus, also called speckled lentiginous nevus, presents itself as a patch of melanization dotted by smaller macules of darker color, frequently occuring on the trunk, and in some respect, resembeing the cafe au lait of von Recklinghausens disease and Albrights syndrome. We present clinical and histopathologic observation made on 14 patients, 13 male and 1 female, who agreed to go through a biopsy, during 5 years period from 1975 to 1980. The age at the visit ranged from 11 years to 61, with a mean of 22. 4. The location of lesions were shouIder (in 5 cases), neck (in 2), back (in 2), trunk (in 4),arm (in 1), and buttock (in 1). The epidermal changes consist of hypererkatosis (in 7), acanthosis (in 6), elongation of rete ridge and papillomatosis (in 9), basilar hypermelanosis (in 14), and nevus cell nests(in 3) The dermal changes consists of mild perivascular lymphoid and histiocytic cellular infiltrations (in 11), chromatophores (in 8) and dilated blood vessels (in 6). It is suggested that nevus spilus should be considered as a giant lentigo, a neoplasia of epictermal melanocytes, where junctional nevus is to develop.
Biopsy ; Blood Vessels ; Buttocks ; Chromatophores ; Female ; Humans ; Hyperpigmentation ; Lentigo ; Male ; Melanocytes ; Neck ; Neurofibromatosis 1 ; Nevus* ; Papilloma

The gate control theory was proposed by Melzack & Wall in 1965. This theory implies that selective stimulation of cutaneous afferent fibers of large diameter inhibits pain. Transcutaneous electrical stimulation(TNS) is a practical employment of this concept. TNS was used on 14 herpes zoster patients to relieve associated pain. Good effeet was obtained in 13 patients. They experienced relief of their pain for 1-4 hours after 20 minutes of application. TNS has many advantages over analgesic drugs in the control of pain in herpes zoster.
Analgesics ; Employment ; Herpes Zoster* ; Humans

In this study, the glycogen depletion and repletion of 4 hind limb skeletal muscles which are composed of different type of muscle fibers were investigated in the streptozotocin induced diabetic rats. At sixth day after intraperitoneal injection of streptozotocin (65mg/kg, BW), the plasma insulin level was decreased to 28.2 ±4.16u U/ml comparing with the level of 49.3 ±9.41 in control rats, And it showed approximatly 300% increment of the level of blood glucose concentration in the sedentary diabetic rats. The soleus (slow oxidative), rad gastrocnemius (fast oxydtive glycolytic), extensor digitorum longus (fast oxidative glycolytic and fast glycolytic mixed), and white gastrocnemius (fast gltycolytic) were subjected in this study. The decreased amount of glycogen in the muscles by 3 minutes treadmill running in disbetic rats was larger than that of control rats. The largest amount of depletion was observed in the soleus in diabetic rats. The repleted amount of muscle glycogen was measured at 2 hours after glucose ingestion (25% glucose sol., 2ml/10gm BW). In the control rats, the highest amount of glycogen was repleted in the soleus, but lowest in white gastrocnemius. The repleted amount of glycogen in soleus, red gastrocnemius, and extensor digitorum longus was lower in the muscles of diabetic rats than in control rats, but no difference was observed in white gastroenemius muscles. These data suggest that glycogen synthetic activities of all of muscles except the muscles which are composed of fast glycolytic fiber, were stimulated by insulin.
Animals ; Blood Glucose ; Eating ; Extremities ; Glucose ; Glycogen ; Injections, Intraperitoneal ; Insulin ; Muscle Fibers, Skeletal ; Muscle, Skeletal ; Muscles ; Plasma ; Rats ; Running ; Streptozocin

No abstract available.
Drainage*

The bilateral vanishing testes syndrome is a rare condition in which the vanishing testes were once present but atrophied due to compromise in blood supply. We present a case of bilateral vanishing testes syndrome which was confirmed with laparoscopy and exploratory laparotomy following hormonal therapy The diagnosis of vanishing testes syndrome can be established by following criteria without surgical exploration. These criteria include a normal male phenotype with XY karyotype, absence of Mullerian structures on rectal examination or ultrasonography, elevated gonadotropins(FSH alone or FSH and LH), and no significant increase in serum testosterone after hCG stimulation. However, patients who do not fit these criteria should have laparoscopy or exploration to look for occult gonadal tissue and spermatic vessels.
Diagnosis ; Gonads ; Humans ; Karyotype ; Laparoscopy ; Laparotomy ; Male ; Phenotype ; Testis* ; Testosterone ; Ultrasonography

From February 1987 to December 1990, 654 patients with renal stones completed the multiple ESWL monotherapies using the EDAP-LT01 piezoelectric lithotriptor. The location of stones was calyx in 452 patients. pelvis in 1O8. calyx and pelvis in 94 and the stone size ranged from 0.6 to 4.8cm (mean 1.9cm). The number of treatment sessions was 2 to 19 sessions (mean 4.7) with 72.2% of re-treatment rate. In accordance with increment of stone size, number of treatment increased but success rate decreased; 2.8 sessions. 96.2% for 0.6-<1 cm. 4.4, 93.2% for 1-<2 cm, 5.5. 87.7% for 2-<3 cm. 6.3, 65.5% for 3-<4 cm and 6.4, 58.8% for stones larger than 4 cm. Supposing 654 patients had been completed by 5 sessions only. 67.9% of success rate would have been expected. But. 88.4% (578,654) of success rate was obtained by multiple treatment up to 19 sessions, adding 20.5%. Auxiliary ureteral manipulations were required in 88 (13.5%) patients and there were no significant complications. Therefore. multiple ESWL monotherapy is considered to be a efficient. safe procedure as the first applicable method for treatment of larger renal stones and to extend the indications of ESWL for renal stone.
Humans ; Pelvis ; Ureter