No abstract available.
Hysterectomy* ; Venous Thrombosis*

PURPOSE: Sexual adverse events (AEs), a major cause for discontinuing 5alpha-reductase inhibitor (5ARI) therapy for benign prostatic hyperplasia (BPH), are known to occur most frequently early in therapy and appear to decline over time. The aim of this study was to investigate the changes in sexual function occurring with dutasteride treatment during a 1-year follow-up period in Korean men. MATERIALS AND METHODS: Using the International Index of Erectile Function, we prospectively evaluated, after 1, 3, 6, 9, and 12 months of treatment, the changes in sexual function of 55 outpatients (mean age 62.3+/-7.2 years) with BPH (mean volume 48.9+/-16.0 g) who had relatively good erectile function (EF) and were treated with dutasteride for at least 1 year. RESULTS: EF scores showed the most significant decrease at 1 month (p<0.01). Function gradually recovered thereafter but was still significantly decreased after 12 months of treatment (p<0.05). The scores for orgasmic function and sexual desire also showed the most significant reduction at 1 month but were restored to the baseline level at 6 months. No significant correlation was observed between changes in sexual function and prostate-specific antigen level, prostate volume, or International Prostate Symptom Scores. CONCLUSIONS: After 1 month of treatment, dutasteride therapy resulted in a significant reduction in all investigated sexual functions. Overall, recovery in sexual function was noted at 3 months, and orgasmic function and sexual desire were restored to baseline levels at 6 months. However, EF was still significantly reduced at 12 months.
Azasteroids ; Erectile Dysfunction ; Follow-Up Studies ; Humans ; Male ; Orgasm ; Outpatients ; Prospective Studies ; Prostate ; Prostate-Specific Antigen ; Prostatic Hyperplasia ; Dutasteride

OBJECTIVE: This study examines the risk factors of the falls of the dementic elderlies in the nursing home. Especially we investigated how the psychotropics affect them in the aspect of the falling tendency. METHODS: We investigated the falls of the 262 patients living in the Seoul JungGae Nursing Home for six month since March 1 1999. Among these we recruited 182 patients whom the exclusion criteria was applied to, and then we measured the relative risks of risk factors known from the previous studies. RESULTS: The incidence rate of falls is 40.1/100person year. The relative risk of gender, age, disease of central nervous system, chronic illness, cognitive function, antipsychotics, antidepressants and anxiolytics had no significance (p>0.05). BADL, mobility, mood stabilizers were related with the falls significantly, and the relative risks were 0.904 (95%CI 0.840-0.973), 1.744 (95%CI 1.064-2.858), 4.683 (95%CI 1.412-15.532) relatively. CONCLUSIONS: The average rate of falling was 40.1/100person year showing less frequent accidents than that of other foreign studies, which was assumed the large number the care-givers and sitting life style on the floor helped preventing the elderlis' falling. Although The gender, age, disease of central nervous system, chronic illness, cognitive function, antipsychotics, antidepressants and anxiolytics did not influence the rate of the falling tendendy of the elderlies, the mobility and impaired activity of daily living increased the rate of their falling. The elderlies taking psychotropics more fell than others not taking pills. The imbalance between the mobile potency and imposed real activity causes the falls. When the psychotropics affect negatively on the mobility, it increases the falling rate of the elderlies. On the other hands, when these affect positively, these prevent elderlies falling.
Anti-Anxiety Agents ; Antidepressive Agents ; Antipsychotic Agents ; Central Nervous System ; Chronic Disease ; Dementia ; Hand ; Humans ; Incidence ; Life Style ; Nursing Homes* ; Nursing* ; Risk Factors* ; Seoul

PURPOSE: The International Prostate Symptom Score(IPSS) is the most commonly used scoring system to evaluate lower urinary tract symptoms(LUTS) in patients with benign prostatic hyperplasia(BPH). A Korean translation of the IPSS, however, has never been clearly confirmed to assess LUTS accurately. The objective of this study was to measure differences in the Korean-language IPSS when administered by the patient versus the physician, and to evaluate causes of the differences. MATERIALS AND METHODS: One-hundred-thirteen patients with symptomatic BPH completed 3 consecutive IPSS questionnaires, one self-administered at the first visit, the second self-administered at the next visit, and the last by a physician interview just after the second self-administration. We compared differences in the symptom scores between the each of the 3 administrations. In addition, the effect of age and education on the scores was analysed. RESULTS: There was no significant difference in the IPSS between the first and the second self-administration. However, physician-administered scores were significantly lower than the two self-administrations(p <0.01) for all questions except #5 regarding urinary stream. The difference in the score was higher in patients whose LUTS were more severe(p <0.01). Age and education did not affect the scores. CONCLUSIONS: There was a significant difference in the IPSS between patient and physician administration, suggesting a need for revision of the Korean version of IPSS.
Education ; Humans ; Prostate* ; Prostatic Hyperplasia ; Surveys and Questionnaires ; Rivers ; Urinary Tract

Recent case reports of the successful application of electroejaculation techniques for seminal emission and subsequent pregnancies have offered promising fertility alternative for the men with neurogenic anejaculation. The success of his program requires multidisciplinary couple-oriented therapy combining both turologic and gynecologic infertility therapy. However, despite obtaining often normal numbers of spermatozoa. sperm motility rarely exceeds 10-20% in electroejaculation sample. Therefore, realistic potential for pregnancy with intrauterine insemination technique is extremely low. In this report we present the first domestic successful coordination of both electroejaculation and in vitro fertilization-embryo transfer in a neurogenic anejaculation patient with severe oligoasthenospermia.
Fertility ; Humans ; Infertility ; Insemination ; Male ; Pregnancy ; Sperm Motility ; Spermatozoa

Background: Deltoid function critically influences the results of reverse total shoulder arthroplasty (RTSA), and spontaneous deltoid attrition tears are frequently detected in cuff tear arthropathy (CTA) patients; however, the clinical impacts of these tears on RTSA outcomes are undetermined. Our aim was to determine the effect of spontaneous deltoid attrition tears on postoperative outcomes after RTSA without an additional deltoid procedure. Methods: Seventy-two patients who underwent RTSA for CTA with preoperative magnetic resonance imaging (MRI) and a minimum clinical follow-up of 1 year (mean, 32 months) were retrospectively reviewed in the study. Patients with a history of previous shoulder surgery or injury were excluded. The presence and location of deltoid attrition tears were determined in preoperative MRI. Propensity score matching (1:1) was performed to construct tear and no-tear groups. Finally, 21 patients, matched with respect to age, sex, hand dominance, symptom duration, medical comorbidity (obesity, diabetes mellitus, and coronary artery disease), Hamada grade, and implant type, were assigned to each group. Clinical outcomes (functional scores, isometric power, and range of motion) in the two groups were compared. Results: Deltoid attrition tears were detected in 21 of the 72 enrolled cases (29.1%). Anterolateral deltoid was the most frequent location and no tear was detected in the posterior deltoid. The tear rate increased with disease severity (Hamada G2, 4.8%; G3, 23.8%; > G4, 71.4%). No pre- or postoperative clinical variables differed significantly between the tear and no tear groups. Conclusions Deltoid attrition tears were detected in 29% of CTA patients who underwent RTSA. The most common site was the anterolateral region and tear prevalence tended to increase with CTA progression. However, RTSA was found to provide satisfactory outcomes regardless of the presence of a deltoid attrition tear.

OBJECTIVES: The purpose of this study is to compare ultimate tensile load of newly designed loop suture technique, to those of Pulvertaft fishmouth suture technique and Kessler suture technique with core strands. MATERIALS AND METHODS: Eight week-old Habbard chickens were sacrificed to harvest flexor digitorum logus tendon of long toe. They were divided into four groups according to suture technique; interweave suture group, loop suture group, Kessler suture group, and normal control group. Twenty tendons were tested in each group. Comparison of cross-sectional areas between each technique was verified by statistical method and the difference was not statistically significant (p>0.05). Tensile load and deformed length were checked by Instron (Model 1000, Instron Corp, Canton, MA). ANOVA test was used for statistical analysis. RESULTS: Ultimate tensile loads were 22.83+/-7.89 N in interweave suture group, 30.58+/-5.96 N in loop suture group, and 10.83+/-4.47 N in Kessler suture group. These results showed statistically significant differences (p<0.001). The values were 33 % in interweave suture, 44% in loop suture, and 15 % in Kessler's suture respectively. Absorbed energy were 0.48+/-0.32 J in interweave suture group, 0.61+/-0.18 J in loop suture group, and 0.22+/-0.15 J in Kessler suture group, and 1.01+/-0.20 J in normal control group. There were statisti - cally significant differences between each groups (p<0.01). CONCLUSION: The loop suture technique showed better biomechanical properties than interweave or Kessler technique. We think the loop suture technique is a simple and useful method, especially for tendon transfer or tendon graft when tendon length is sufficiently long to make a good tendon overlap.
Chickens* ; Suture Techniques* ; Sutures* ; Tendon Transfer ; Tendons* ; Toes ; Transplants

BACKGROUND: Arthroscopic rotator cuff repair generally has a good clinical outcome but shoulder stiffness after surgery due to subacromial adhesion is one of the most common and clinically important complications. Sodium hyaluronate (HA) has been reported to be an anti-adhesive agent in a range of surgical procedures. However, there are few reports of the outcomes of arthroscopic rotator cuff repair of the shoulder. This study examined whether a subacromial injection of HA/carboxymethylated cellulose (CMC) affected the postoperative shoulder stiffness and healing of rotator cuff repair, as well as the safety of an injection. METHODS: Between January 2008 and May 2008, 80 consecutive patients with arthroscopic rotator cuff repair were enrolled. The patients were assigned randomly to the HA/CMC injection group (n = 40) or control group (n = 40). All patients were evaluated using the visual analog scale (VAS) for pain, passive range of motion at 2, 6 weeks, 3, 6, 12 months after surgery, and the functional scores at 6, 12 months postoperatively. Cuff healing was also evaluated using CT arthrography or ultrasonography at 6 or 12 months after surgery. RESULTS: The HA/CMC injection group showed faster recovery of forward flexion at 2 weeks postoperatively than the control group but the difference was not statistically significant (p = 0.09). There were no significant difference in pain VAS, internal rotation, external rotation and functional scores between two groups at each follow-up period. The functional scores improved 6 months after surgery in both groups but there were no differences between the two groups. The incidence of unhealed rotator cuff was similar in the two groups. There were no complications related to an injection of anti-adhesive agents including wound problems or infections. CONCLUSIONS: A subacromial injection of an anti-adhesive agent after arthroscopic rotator cuff repair tended to produce faster recovery in forward flexion with no adverse effects on cuff healing. However, its anti-adhesive effects after rotator cuff repair should be considered carefully with further studies.
Adult ; Aged ; Arthroscopy/*adverse effects/*methods ; Carboxymethylcellulose Sodium ; Drug Carriers ; Female ; Humans ; Hyaluronic Acid/adverse effects/*therapeutic use ; Male ; Middle Aged ; Pain ; Prospective Studies ; Range of Motion, Articular ; Recovery of Function ; Rotator Cuff/injuries/*surgery ; Shoulder Joint/physiology ; Tissue Adhesions/*prevention & control ; Treatment Outcome ; Viscosupplements/adverse effects/*therapeutic use

PURPOSE: The aim of this study was to evaluate the effects of the wrist stretching exercise on the results of treatment for lateral epicondylitis by comparing with wait-and-see policy. MATERIALS AND METHODS: The patients who had lateral elbow pain associated with a lateral epicondyltitis were divided into wrist extension stretching exercise group (group 1) and wait-and-see policy group (group 2). Group 1 pateitns were educated to perform the wrist stretching exercise; maintenance of the position with the elbow extended, the forearm pronated, and the wrist flexed for more than 1 minute, more than 50 times per day. Group 2 patients were educated that they reduced the activities that provoked pain. The end point of follow-up was when symptoms were disappeared completely. RESULTS: Two hundred twenty seven patients were enrolled into this study. One hundred forty eight patients were allocated to group 1, 79 patients to group 2. The mean duration of follow-up of group 1 was 10.2 weeks and group 2 was 22.6 weeks. The median survival time from symptom onset to the time of resolution was 8.0 weeks in group 1, 16.0 weeks in group 2. CONCLUSION: This study suggests that wrist stretching exercise may be more effective than the wait-and-see policy in the patients with a lateral epicondylitis. The wrist stretching exercise can be recommended as the treatment of lateral epicondylitis.
Elbow ; Follow-Up Studies ; Forearm ; Humans ; Wrist

Adipose-derived stem cells (ASCs) are believed to have potential use for treating many illnesses. Most cells, including ASCs, are generally cultured in medium containing fetal bovine serum (FBS). However, FBS, which could induce an immune response or infection, is not recommended for clinical applications. In the present study, we evaluated the morphology, proliferation rate, and characterization of rabbit ASCs grown in medium containing autologous serum (AS) and compared these cells to ones cultured with FBS. Morphological changes were monitored by microscopy and flow cytometry. Proliferation rates were assessed with cell counting and ASC phenotypes were characterized by flow cytometry using representative surface markers (CD44 and CD45). Expression of epidermal growth factor, brain-derived neurotrophic factor, and vascular endothelial growth factor was measured by reverse transcription-polymerase chain reaction. Results of our study showed that ASCs had a greater expansion rate in AS without developing morphological heterogeneity than cells grown in FBS. AS-cultured ASCs expressed representative growth factors, CD44 but not CD45, similar to cells cultured in FBS. Expression levels of some growth factors were different between AS and FBS. In conclusion, our findings indicated that AS could potentially be used as a culture medium supplement for the expansion of autologous ASCs.
Brain-Derived Neurotrophic Factor ; Bystander Effect ; Cell Count ; Epidermal Growth Factor ; Flow Cytometry ; Intercellular Signaling Peptides and Proteins ; Microscopy ; Phenotype ; Population Characteristics ; Stem Cells ; Vascular Endothelial Growth Factor A