1.A Case of Pulmonary Microsporidiasis in an Acute Myeloblastic Leukemia (AML) -M3 Patient.
Suleyman YAZAR ; Bulent ESER ; Saban YALCIN ; Izzet SAHIN ; A Nedret KOC
Yonsei Medical Journal 2003;44(1):146-149
Reported here is a case of microsporidiasis that occurred in an acute myeloblastic leukemia (AML) -M3 patient who underwent chemotherapy. Fever, cough, expectorate and dyspnea were observed during the therapy. Since this case was considered as adult respiratory distress syndrome due to the chest X-ray and arterial blood gas findings, the male patient was bounded to a mechanical ventilator. As coagulation tests showed compatible findings with disseminate intravascular coagulation (DIC), it was thought to be a case of sepsis originating from the lungs and DIC. Pseudomonas aeruginosa and Staphylococcus aureus were found in the sputum of the patient. Although he was given combined antibiotic therapy, there was no reduction in the fever. A bronchoalveolar lavage (BAL) sample was taken and Microsporidia sp. was found upon staining with Giemsa. The patient died due to sepsis and DIC just before receiving therapy for microsporidiasis. Pulmonary infection with Microsporidia, although classically occurring in patients with HIV infection, may occur rarely in leukemia patients, especially if previously treated with systemic immune suppression. This case reinforces the need to consider Microsporidia as a possible pathogen in immunocompromised patients with pulmonary infections.
Diagnostic Errors
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Fatal Outcome
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Human
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Immunocompromised Host
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Leukemia, Myelocytic, Acute/*complications
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Lung Diseases, Parasitic/*complications/diagnosis
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Male
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Microsporidiosis/*complications/diagnosis
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Middle Aged
2.Anti-Toxoplasma gondii Antibodies in Haemodialysis Patients with Chronic Renal Failure.
Suleyman YAZAR ; Funda DEMIRTAS ; Saban YALCIN ; Ozan YAMAN ; Bulent TOKGOZ ; Cengiz UTAS ; Izzet SAHIN
Yonsei Medical Journal 2003;44(2):288-292
This study aimed to determine the prevalence of anti- Toxoplasma gondii antibodies in haemodialysis patients with chronic renal failure (CRF). Methods: One hundred and seventy three haemodialysis patients, and 40 healthy controls, were studied for the prevalence of anti-Toxoplasma gondii antibodies by a micro enzyme-linked immunosorbent assay (ELISA). Anti-T. gondii IgG antibodies were detected in 97 (56.06%) haemodialysis patients and 8 (20%) controls with a statistical significance. In addition, anti-T. gondii IgM antibodies were detected in 1.73% of patients, but none of the controls. In conclusion, a high percentage of positivity for Toxoplasma antibodies in patients with CRF undergoing haemodialysis was noticed, thus parasitological surveys of CRF patients should be periodically performed to prevent the possible dissemination of toxoplasmosis through the dialysis procedure.
Adolescent
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Adult
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Aged
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Aged, 80 and over
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Animals
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Antibodies, Protozoan/*blood
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Human
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Kidney Failure, Chronic/*immunology/therapy
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Middle Aged
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*Renal Dialysis
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Toxoplasma/*immunology
3.Nosocomial Oral Myiasis by Sarcophaga sp. in Turkey.
Suleyman YAZAR ; Bilal DIK ; Saban YALCIN ; Funda DEMIRTAS ; Ozan YAMAN ; Mustafa OZTURK ; Izzet SAHIN
Yonsei Medical Journal 2005;46(3):431-434
We present a case of oral myiasis in a 15-year-old boy with tuberculosis meningitis. The diagnosis was based on the visual presence of wriggling larvae about 1 cm in size and on the microscopic features of the maggots, especially those relating to stigmatic structures. The larvae were identified as third stage larvae of Sarcophaga sp.
Adolescent
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Animals
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Cross Infection/microbiology/*parasitology
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*Diptera
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Fatal Outcome
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Humans
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Male
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Mouth Diseases/complications/*parasitology
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Myiasis/complications/*diagnosis
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Tuberculosis, Meningeal/complications
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Turkey