1.Renal oncocytoma (report of 3 cases and review of literature)
Yinglong SA ; Yuemin XU ; Youzhang XU
Chinese Journal of Urology 2000;0(12):-
Objective To improve the diagnosis and treatment of renal oncocytoma. Methods The clinical data of 3 cases with renal oncocytoma treated from 1999 to 2002 were retrospectively analyzed and discussed with literature reviewed. The 3 tumors’size was 7.6 cm?8.5 cm?6.8 cm,10.0 cm?11.5 cm?9.8 cm,10.0 cm?8.0 cm?6.8 cm,respectively.The clinical features were atypical.Renal oncocytoma was characterized by homogeneous attenuation with a central, margined stellate area on CT scan. Results The 3 cases underwent nephrectomy,and the resected tumors were examined by pathology.On light microscopy,there was strong eosinophilic cytoplasm with granules,the tumor cells being tubular or adenoid in pattern with no necrosis and very rare or no mitosis.Enormous mitochondria were noted on electron microscopy.The immunohistochemical staining was positive for cytokeratin and EMA,whereas it was negative for vimentin.The follow-up lasted for 16 to 30 months without recurrence or metastasis. Conclusions Renal oncocytoma is a type of benign,parenchymatous tumor,and it has no specific clinical feature.The diagnosis can be established on histopathologic,immunohistochemical and electron microscopic studies.
2.Ultrasound guided transperineal prostatic biopsy for the diagnosis of prostatic cancer
Yinglong SA ; Yuemin XU ; Yajing CHENG
Chinese Journal of Urology 2001;0(11):-
10 ng/ml). Results The diagnost ic rate of 3 groups was 44.5%,29.8%,57.4% respectivly. Conclusions The advantages of the procedure were correct acquiring of prastate ti ssue,more accurate approach and depth of the puncturing needle,avoiding injury t o the nearby tissue and raising the diagnosis rate of prostatic carcinoma.
3.Enhanced continent mechanism of tapered ileum by suspension technique
Yuemin XU ; Yong QIAO ; Yinlong SA
Chinese Journal of Urology 2000;0(12):-
Objective To construct a reliable and continent urinary reservoir,which is surgically simple. Methods (8 adult mongrel female dogs underwent a procedure in which an ileal segment was tapered as an efferent tube and a 1.5 cm in width of Dilurn polyester with a tension of 400g was used to suspend the efferent tube to enhanced the continent mechanism of the tapered ileum.) Urodynamic and radiological studies were carried out postoperatively in all. Results All the stomas could be easily catheterized with a 14 F catheter. The urodynamic study of the efferent tubes showed the maximum close pressure ranged from 117 cmH 2O to 157 cmH 2O,with a mean of 137 cmH 2O.Retrograde radiogram showed perfect canalization of the efferent tube without stenosis and pouchgram revealed no contrast medium in the efferent tube. Conclusions This study suggested that the continent mechanism of tapered ileum can be greatly enhanced by the suspension technique.
4.The bulbourethral sling procedure for post-prostatectomy incontinence
Yuemin XU ; Xinru ZHANG ; Yinglong SA
Chinese Journal of Urology 2001;0(03):-
Objective To evaluate bulbourethral sling procedure in the treatment of post prostatectomy incontinence. Methods 5 patients with post prostatectomy incontinence underwent the bulbourethral sling procedure.Preoperatively 1 patient was completely incontinent and 4 patients required a mean of 3.5 pads per day.The mean duration of incontinence was 4.5 years. A sling tension of a mean of 500 g was used to correct incontinence. Results 4 patients have been completely dry,whereas postoperative difficulty in voiding occurred in the other patient and was corrected by subsequent transurethral bladder neck revision resulting in free passage of urine and continence. Conclusions The bulbourethral sling procedure is an effective means in the treatment of post prostatectomy incontinence.
5.Nonspecific granulomatous prostatitis (report of 26 cases)
Yinglong SA ; Yuemin XU ; Yong QIAO
Chinese Journal of Urology 2001;0(11):-
Objective To elucidate the clinical features of nonspecific granulomatous prostatitis(NSGP). Methods From February 1994 to February 2002,26 cases of NSGP confirmed histologically were retrospectively analysed.Of them 20 cases were treated with anti-inflammatory therapy alone;4 cases with anti-inflammatory therapy plus ?-receptor blocker,and 2 cases who concomitantly had retention of urine underwent TURP. Results All the 26 patients were followed up for 6 to 42 months.The therapeutic results were satisfactory.The Qmax increased from 4.6~12.8 ml/s to 16~28 ml/s,and the hard prostate mass became soft,with reduction from 2.5 cm?3.5 cm to 0.5 cm?1.0 cm.The serum PSA decreased from 15.5~60.8 ng/ml to 1.5~10.6 ng/ml. Conclusions In clinical practice NSGP is often mistaken for prostatic carcinoma,so special attention should be paid to the differential diagnosis.The definite diagnosis depends on histopathological examination.
6.Effect of Electroacupuncture at Point Zusanli (ST36) on Gastric HSP70 mRNA in Rats with Stress Gastric Ulcer
Xiaoxiang ZHU ; Zheyan SA ; Shuxia ZHENG ; Xiaohua PAN ; Jinsen XU
Shanghai Journal of Acupuncture and Moxibustion 2015;(6):585-587
Objective To investigate the effect of electroacupuncture at point Zusanli (ST36) on gastric expression of heat shock protein 70 (HSP70) mRNA in rats with stress gastric ulcer and explore the molecular mechanism of its prevention and treatment of gastric ulcer. Method Fifty-one SD rats were randomly allocated to normal control (normal), stress gastric ulcer (model) and electroacupuncture at point Zusanli (electroacupuncture) groups. A model of stress gastric ulcer was made by cold restraint. From the second day after model making, the electroacupuncture group received electroacupuncture at point Zusanli 20 min once daily for three consecutive days, with left and right points Zusanli alternately needled; the model group, the same restraint treatment as in the electroacupuncture group; the normal group, no treatment. Gastric mucosal ulcer index (UI) was calculated using the GUTH’s method. The pathological morphology of gastric tissue was observed by HE staining. Gastric HSP70 mRNA expression was determined by RT-PCR. Result Different numbers and sizes of obvious gastric mucosal ulcers were observed, UI increased significantly (P<0.001) and HSP70 mRNA expression decreased significantly (P<0.05) in the model group compared with the normal group. The pathological change in gastric tissue improved somewhat, gastric mucosal UI decreased significantly (P<0.05) and HSP70 mRNA expression increased significantly (P<0.01) in the electroacupuncture group compared with the model group. Conclusion Electroacupuncture at point Zusanli can upregulate gastric HSP70 mRNA expression and promote the repair of gastric mucosa injuries in rats with stress gastric ulcer.
7.Trauspubic access using pedicle labial skin flap urethroplasty for the treatment of female urethral stric-tures associated with urethrovaginal fistulas
Yuemin XU ; Yinglong SA ; Qiang FU ; Jiong ZHANG ; Sanbao JIN
Chinese Journal of Urology 2008;29(12):853-854
Objective To evaluate the efficacy of transpubie access using pedicle tabularized la-bial urethroplasty for urethral reconstruction in female patients with urethral strictures associated with urethrovaginal fistulas.Methods Eight cases of urethral strictures were treated using pedicle labial skin flaps for urethral reconstructions.All cases were the mid-urethral strictures associated with ure-throvaginal fistulas.A single face pedicle flap was obtained from the labia minus or majus in 5 women,and double face pedicle labial flaps were used in 3 patients.Results There were no serious complica-tions.Two patients complained of dysuria symptoms for 2 weeks and one patient experienced stress incontinence which resolved after 4 weeks.The patients were followed up for 6 to 130 months (mean 52) postoperatively.All patients had normal micturition following catheter removal with urinary peak flow greater than 15 ml/s(17.4-42.0 ml/s).Conclusion Pedicle labial urethroplasty might be a reliable technique for the management of complex urethral strictures associated with urethrovaginal fis-tulas.
8.Selection of operative approaches for the treatment of complicated urethral strictures
Yuemin XU ; Yinglong SA ; Qiang FU ; Jiong ZHANG ; Sanbao JIN
Chinese Journal of Urology 2009;30(12):856-858
Objective This study was to discuss various operative approaches for the repair complicated posterior urethral strictures. Methods 34 patients with posterior urethral strictures and associated ure-throrectal fistulas (URFs) were reviewed. The etiology of urethral strictures and fistula was due to pelvic fracture in 26 patients, iatrogenic in 6 cases and fall injury in the remaining 2 cases. The patients were treated by using a simple perineal approach (4 patients), a transperineal inferior pubectomy approach (21 patients) and combined abdominal transpubic perineal approach (9 patients) and URF repair and anastomotic urethroplasty were performed simultaneously in all cases. Results One-stage repair was successful in four patients (100%) using a simple perineal approach, in 19 of 21 (90. 48%) using the transperineal-inferior pubectomy approach and 7 of 9 (77. 78%) using the transpubic-perineal approach. Of the 34 patients, recurrent urethral strictures developed in two cases, recurrent URFs developd in two patients. Conclusions Surgical approaches for the special complex urethral strictures should be based on the location of the URF, its etiology and length of the urethral strictures, as well as a history of previous repairs. The transperineal-inferior pubic approach may be appropriate as a first-line procedure.
9.Application of 3-dimensional CT reconstruction in the diagnosis of posterior urethral strictures or ankylurethria
Yagang XUE ; Yinglong SA ; Lujie SONG ; Jiemin SI ; Yuemin XU
Chinese Journal of Urology 2010;31(1):59-62
Objective To study the diagnostic value of 3-dimensional CT reconstruction in posterior urethral strictures or ankylurethria.Methods Thirty patients with strictures or ankylurethria of posterior urethra caused by pelvic fracture underwent helical CT scan and 3-dimensional reconstruction of the urethral canal as well as radiographic urethrography before and post open urethral reconstruction to observe the urethral anatomy,the length and position of the urethral strictures,the depth of periurethral scar.Results The mean stricture or ankylurethria length measured by radiographic urethrography was 4.0 cm (range from 1.0 cm to 7.0 cm),and the correlation coefficient of stricture or ankylurethria length was 0.92,21 (70%) patients were diagnosed accurately by radiographic urethrography.The mean stricture or ankylurethria length measured by 3-dimensional CT reconstruction was 4.3 cm (range from 1.2 cm to 7.6 cm),and the correlation coefficient of stricture or ankylurethria length was 0.96,there were 28(93%) patients diagnosed accurately by 3-dimensional CT reconstruction.The mean stricture or ankylurethria length measured by open urethral reconstruction was 4.2 cm (range from 1.5 cm to 7.5 cm).Five patients with urethrorectal fistula were also diagnosed accurately by 3-dimensional CT reconstruction rather than by radiographic urethrography.Conclusions 3-dimensional CT reconstruction of the urethral canal can accurately evaluate the urethral anatomy,the length and position of the urethral strictures,as well as the depth of periurethral scar after crush injury and provide useful information for operation that may not be provided by radiographic urethrography.3-dimensional CT reconstruction may become the most valuable means for detecting posterior urethra strictures or ankylurethria with urethrorectal fistula.
10.Effect of Electroacupuncture of Different Acupoints on Electroretinogram and Cerebral Visual Evoked Potentials in Healthy Subjects
Jinsen XU ; Xiaohua PAN ; Xianglong HU ; Zheyan SA ; Shuxia ZHENG
Acupuncture Research 2010;0(01):-
Objective To observe the effect of electroacupuncture(EA) of different acupoints on electroretinogram(ERG) and cerebral visual evoked potentials(VEP) in healthy subjects so as to evaluate the relative specificity of the function of acupoints.Methods A total of 33 healthy adult volunteers were observed in the present study.The subject was asked to lie on a testing bed for a while,two disk electrodes were respectively fixed to the suborbital region and the occiput(the crossing point,5cm apart from the right median line of the head and 5cm above the ear),and the reference electrode was fixed to the medial side of the earlobe for recording ERG and cerebral VEP separately.The testing room was asked to keep faint light during the whole recording process.A flash stimulation(frequency 1 Hz) was applied to the subject's eye(with a distance of about 50 cm between the light source and the tested eye,and the other eye was covered by an eyepatch).EA(0.5 Hz,0.2 ms and 3-4 V) was applied to Guangming(GB 37),Neiguan(PC 6) and Zusanli(ST 36) for 30 min respectively in different testing days(with the interval being 3 days at least).ERG and cerebral VEP were recorded by using Polygraphy(RM-6200).Results Following EA of Guangming(GB 37),Neiguan(PC 6) and Zusanli(ST 36),the changing values(increase and decrease) of the amplitude of b waves of ERG and P100 waves of cerebral VEP were(19.68?12.61)% and(12.84?14.08)%,(6.09?14.06)% and(5.61?8.01)%,(2.39?3.52)% and(5.43?8.22)%,respectively,while those of b waves of ERG and P100 waves of cerebral VEP of GB 37 were significantly bigger than those of PC 6 and ST 36(P