1.A Case of Early Infantile Epileptic Encephalopathy with Suppression-burst.
Journal of the Korean Pediatric Society 1989;32(9):1321-1324
No abstract available.
2.Auditory Brain Stem Responses and Neurological Disorders in Children.
Journal of the Korean Pediatric Society 1994;37(2):149-156
No abstract available.
Child*
;
Evoked Potentials, Auditory, Brain Stem*
;
Humans
;
Nervous System Diseases*
3.Changes in somatostatin immunoreactive neurons in rat cerebral cortex after systemic kainic acid administration.
Myung Yeun LEE ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1993;36(9):1279-1290
This study was aimed to clarify the effects of systemic kainic acid (KA) administration (10 mg/kg i.p.) on somatostatin containing neurons, and to examine the distribution of somatostain immunoreactive neurons in the cerebral cortex of the rats. Animals were sacrificed at three time points at the two, six, and ten days after the injection of KA. Thirty-six rats were observed by using the free-floating immunohistochemical method (modified ABC method). The results were as follows: 1) In the anterior and posterior cingulate cortex, somatostatin immunoreactive neurons were not observed in 2,6,10days after treatment of KA including control group except Cg 1 showing some somatostatin immunoreactive neurons in 10days and control groups. 2) In the insular cortex, somatostatin immunoreactive neurons also were not observed in any groups except AIV showing few somatostatin immunoreactive neurons in control group. 3) In the perirhinal cortex, few somatostatin immunoreactive neurons were observed in 2 days and 6 days groups. In control group, a number of somatostatin immunoreactive neurons observed. 4) A strong decrease of somatostatin immunoreactive neurons were observed in the frontal, arietal, temporal and occipital cortex 2 days after treatment of KA. Initially decreased somatostatin immunoreactive neurons had recovered to control 10 days after treatment. 5) Distribution of the somatostatin immunoreactive neurons was observed marked difference according to the cortical areas. Somatostatin immunoreactive neurons in isocortex were more increased in number than the allcotex by control study. The changes in somatostatin immunoreactive neurons after systemic treament of KA were marked in 2 days and 6 days, but these had recovered to control 10 days the treatment of KA. It suggested the normalization of the cerebral function 10 days after seizure. According to the cerebral cortex, the different distribution of somatostatin immunoreactive neurons in number was observed.
Animals
;
Cerebral Cortex*
;
Gyrus Cinguli
;
Kainic Acid*
;
Neurons*
;
Rats*
;
Seizures
;
Somatostatin*
4.Changes in Auditory Brainstem Reponses (ABR) in Severe Hyperbilirubinemic Neonates with Transient Bilirubin Encephalopathy.
Chong Woo BAE ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1990;33(9):1216-1222
No abstract available.
Bilirubin*
;
Brain Stem*
;
Humans
;
Infant, Newborn*
;
Kernicterus*
5.Postictal Serum Prolactin Values and Its Significance in Convulsive Disorder.
Wan Yong SHIN ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1994;37(11):1573-1578
The authors analysed 196 cases of convulsive disorder in children who were admitted to the pediatric department of Kyunghee Hospital from June 1993. Blood samples were drawn immediately following seizures on arrival. Serum prolactin values were measured by radioimmunoassay. The results obtained were as follows: 1) Mean serum prolactin value was 55.4+/-20.8ng/ml in generalized seizures within 1 hr following seizures, 22.5+/-3.9ng/ml in partial seizures. There was a significant difference between generalized scizures and partial scizures (p<0.05). 2) Mean serum prolactin value was 23.5+/-9.7ng/ml in generalized seizures within 1~3 hrs following seizures, 10.4+/-4.9ng/ml in partial seizures. There was a significant difference between generalized seizures and partial seizures (p<0.05). 3) Mean serum prolactin value was 9.5+/-4.4ng/ml in generalized seizures 3 hrs following seizures, 9.8+/-4.8ng/ml in partial seizures. There was no significant difference between generalized seizures and partial seizures (p>0.05). We found transient hyperprolactinemia following generalized seizures but a little change following gartial seizures. Postictal elevation of serum prolactin may represent a biochemical marker of generalized and partial seizures.
Biomarkers
;
Child
;
Humans
;
Hyperprolactinemia
;
Prolactin*
;
Radioimmunoassay
;
Seizures
6.Experimental study on the effect of phenobarbital on Na+, K+-activated adenosine triphosphatase in microsome fractions of mouse brain.
Seo Kyu KIM ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1991;34(7):959-970
No abstract available.
Adenosine Triphosphatases*
;
Adenosine*
;
Animals
;
Brain*
;
Mice*
;
Microsomes*
;
Phenobarbital*
7.An experimental study on the effect of diphenylhydantoin and gaba on Na+, K=+ - atpase in microsomal fraction of rat brain.
Sa Jun CHUNG ; Kyun Kil YOON ; Chang Il AHN
Journal of the Korean Child Neurology Society 1993;1(1):33-40
No abstract available.
Adenosine Triphosphatases*
;
Animals
;
Brain*
;
gamma-Aminobutyric Acid*
;
Phenytoin*
;
Rats*
8.Two Case of Transient Bilirubin Encephalopathy in Newborn.
Eun Kyoung SOHN ; Chong Woo BAE ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1989;32(9):1295-1299
No abstract available.
Bilirubin*
;
Humans
;
Infant, Newborn*
;
Kernicterus*
9.A Case of Lissencephaly with West Syndrome.
Byoung Yul LIM ; Ji Ho SONG ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1990;33(10):1413-1417
No abstract available.
Infant
;
Infant, Newborn
;
Lissencephaly*
;
Spasms, Infantile*
10.A case of congenital goiter with congenital hypothyroidism due to organification defect.
Ik Hee LEE ; Sung Yong JUNG ; Thi Hyung PARK ; Sa Jun CHUNG ; Chang Il AHN
Journal of the Korean Pediatric Society 1993;36(7):1002-1008
We experienced a case of congenital goiter with congenital hypothyroidism in 45 day-old male, who complained of respiratory difficulty and anterior neck mass. After admission, he was diagnosed congenital hypothyroidism by the clinical manifestations and laboratory tests including biochemistry, radioimmunoassay, radioisotope study, perchlorate discharge test, and bone radiography. We obtained positive finding at the perchlorate discharge test and found that his congenital goiter with congenital hypothyroidism was manifested by organification defect. We started treatment with L-thyroxine orally at 6th hospital day. The case was presented with brief review of literatures.
Biochemistry
;
Congenital Hypothyroidism*
;
Goiter*
;
Humans
;
Male
;
Neck
;
Radiography
;
Radioimmunoassay
;
Thyroxine